2026 July-2 - 435 articles
Background/Objectives: Bilateral thoracoscopic sympathectomy (BTS) is the definitive treatment for primary focal hyperhidrosis, yet postoperative pain remains an undertreated consequence with no established analgesic consensus. This study compared th...
Background: The alarming trend of rising depression and insomnia among the world’s population, especially in young adults, demands urgent attention from both clinical and lifestyle medicine perspectives. This study aimed to evaluate whether hab...
Background: This retrospective study introduces an AI-driven VitalCare-Major Adverse Event Score (VC-MAES) developed to predict major in-hospital adverse events and determine optimal cutoff thresholds. VC-MAES was originally developed to predict a co...
Background/Objectives: Some patients with severe hypoxic–ischemic brain injury after out-of-hospital cardiac arrest (OHCA) progress toward brain death, a trajectory not adequately captured by the conventional classification of favorable versus...
Background/Objectives: Systemic inflammation is common in patients with cancer and may reflect tumor activity, disease extent, and the patient’s overall clinical condition. The systemic immune-inflammation index (SII), calculated from neutrophi...
Hypochloremia has recently emerged as an independent prognostic marker in heart failure (HF), which is especially common in older adults, where it represents a main cause of death and hospitalization. This narrative review of the literature aims to s...
Background/Objectives: Migraine is a complex neurovascular disorder with a multifactorial genetic basis and remains a leading cause of neurological disability worldwide. The angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism ha...
Heart failure (HF) remains a major global health burden despite substantial therapeutic advances. Vericiguat, an oral soluble guanylate cyclase (sGC) stimulator, represents a distinct pharmacological strategy targeting impaired nitric oxide–sGC...
Background/Objectives: Chronic kidney disease is a growing global health concern, necessitating effective tools for early detection and monitoring. While non-contrast T1-weighted magnetic resonance imaging offers a non-invasive means to assess kidney...
Background: Pathological N staging remains central to prognostic assessment in colorectal adenocarcinoma; however, it captures nodal disease as an absolute count and does not account for the total number of examined lymph nodes. The lymph node ratio...
Background and Objectives: The effect of suture material on clinical outcomes in cervical cerclage remains debated. This pilot study compared two braided polyester suture materials with different manufacturing characteristics (Mersilene® and Unie...
Background/Objectives: The increasing use of cardiovascular implantable electronic devices has increased the need for transvenous lead extraction (TLE), which carries a relevant complication risk. The SAFeTY score was developed to predict procedure-r...
Background: Decellularized extracellular matrix (ECM) patches have emerged as a potential alternative to synthetic and autologous materials in pediatric cardiac surgery; however, clinical data on their use in septal defect repair remain limited. Meth...
Background/Objectives: Intra-abdominal hypertension (IAH) is a common but under-recognized condition in critically ill patients and is associated with adverse outcomes, particularly acute kidney injury (AKI) and mortality. However, the prognostic val...
Background/Objectives: The clinical management of hemophilia has evolved with the introduction of innovative therapies that are reshaping treatment paradigms. Real-world implementation of these approaches may vary across centers. This modified Delphi...
Background: Atypical hemolytic uremic syndrome (aHUS) is a life-threatening thrombotic microangiopathy driven by uncontrolled activation of the complement alternative pathway, with pregnancy triggering 10–20% of cases (pregnancy-associated aHUS...
Background: Breast cancer patients are exposed to cardiovascular complications related to both pre-existing cardiovascular risk factors and cardiotoxic cancer therapies. Heart failure with preserved ejection fraction (HFpEF) is an emerging and often...
Bleeding is one of the most common and feared complications after coronary angiography and percutaneous coronary intervention (PCI). It is associated with longer hospital stays, higher mortality, and worse clinical outcomes. As the number of patients...
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) affects nearly one-fourth of the world population and is closely linked to obesity, metabolic syndrome, and poor diet. We conducted a systematic review and meta-analysis to...
Background: Anorexia Nervosa (AN) triggers profound metabolic and psychological adaptations during adolescence. This study investigated the relationships between resting energy expenditure (REE), body composition, physical activity (PA), and specific...
Background and Objectives: Foot bone marrow edema of presumed algodystrophic or bone marrow edema syndrome-like origin is clinically difficult to classify, and the relationship between MRI extent, pain severity, and functional impairment remains insu...
Background/Objectives: Hidradenitis suppurativa (HS), a chronic, inflammatory skin condition, severely affects quality of life. Despite advances in understanding its pathophysiology, major gaps persist in diagnosis and management. This study examined...
Background/Objectives: Placental abruption has a high risk of recurrence, but the timing of recurrence relative to the previous episode remains unclear. This study described the gestational-age distribution of recurrent placental abruption and compar...
Background: This study aimed to investigate the association between serum potassium levels and the risk of cardiac arrest in patients admitted to the emergency resuscitation room and to identify the optimal potassium range associated with the lowest...
Background/Objectives: The safety of hypofractionated postmastectomy radiotherapy (HF-PMRT) in patients undergoing implant-based breast reconstruction remains uncertain because of concerns regarding radiation-related reconstructive complications. We...
Objective: The aim of this study is to identify clinical and obstetric factors associated with acute postoperative pain in pregnant women undergoing primary elective cesarean section and, in particular, to investigate the relationship between intraop...
Background/Objectives: To assess the refractive and visual outcomes after implantation of an isofocal optic-design intraocular lens (IOL) with double C-loop haptics following cataract surgery in eyes with primary open-angle glaucoma (POAG). Methods:...
Background: Recurrent lumbar disc herniation (rLDH) significantly impairs outcomes following percutaneous endoscopic lumbar discectomy (PELD). Accurate individualized risk prediction remains challenging. This study aimed to develop and compare multip...
Background: Accurate pedicle screw placement remains essential in spinal instrumentation, and robotic navigation has been introduced to improve safety, reproducibility, and workflow standardization. This study evaluated the accuracy of robot-assisted...
Background: Alcohol-associated fatty liver disease (AFLD) is a major public health concern and remains one of the leading causes of chronic liver disease in the United States. Understanding the interplay between obesity, metabolic dysfunction, and li...
Community-acquired pneumonia is one of the main causes of morbidity and mortality due to infections worldwide. This has led to the study of the use of corticosteroids as adjunctive therapy, which has shown an inclination to provide clinical benefits....
Purpose: The aim of this study was to test the hypothesis that Tenascin-C (TNC) levels increase following thoracic radiotherapy (RT), and that elevated serum TNC levels are associated with corresponding increases in myocardial TNC expression in histo...
Background: Invasive coronary angiography has historically been the reference standard for coronary, valvular, and structural heart disease. Over the past decade, coronary computed tomography angiography (CCTA), CT-derived fractional flow reserve (CT...
Background/Objectives: Acute heart failure (AHF) is a leading cause of global morbidity, necessitating the search for reliable biomarkers to guide risk stratification. While hyperuricemia is highly prevalent in heart failure patients and historically...
Background/Objectives: Intracochlear electrocochleography (ECochG) is increasingly used to monitor cochlear function during cochlear implantation, particularly in patients with residual hearing. However, optimal acquisition parameters and interpretat...
Breast implant illness (BII) describes a constellation of systemic symptoms reported by some patients after breast implantation, including fatigue, cognitive dysfunction, arthralgia, myalgia, sicca symptoms, skin manifestations, and mood disturbance....
Background: Repeated radiographic monitoring exposes scoliosis patients to cumulative radiation. Dynamic infrared thermography (DIT) may provide a non-invasive alternative by characterizing thermal recovery behavior following controlled cooling. This...
Background: Coronary artery bypass grafting (CABG) is the standard revascularization procedure, and the left internal mammary artery (LIMA) is the most widely used conduit owing to its long-term patency and favorable impact on survival. Although fibr...
Diabetes Mellitus (DM) is becoming increasingly prevalent among young men. While DM is known to cause a myriad of health issues ranging from cardiovascular complications to vision loss, its impact on male reproductive health is often unrecognized. In...
Background/Objectives: Reflux remains one of the main limitations of one-anastomosis gastric bypass (OAGB), potentially impairing postoperative quality of life and requiring revisional surgery in refractory cases. Conversion to Roux-en-Y gastric bypa...
Background/Objectives: The aim of this study was to evaluate the efficacy and safety of avatrombopag in patients with chronic liver disease (CLD) and thrombocytopenia scheduled for elective invasive/minimally invasive procedures, providing clinical g...
Background: Due to inconsistent evidence regarding oral P2Y12 inhibitors in patients with ACS, we critically assessed the results of the PL-ACS registry in comparison to the results of randomized clinical trials (RCTs). Methods: Publications describi...
Background/Objectives: Rectal gastrointestinal stromal tumors (GISTs) near the dentate line (DL) present significant surgical challenges due to anatomical constraints and difficulty preserving anal function. Endoscopic intermuscular dissection (EID)...
Objective: We aimed to quantify the prognostic value of glucose monitoring-derived time in range (TIR), including continuous glucose monitoring (CGM), flash glucose monitoring (FGM), and fingertip capillary glucose monitoring (FCGM), for predicting a...
Respiratory medicine is transitioning from symptom-driven, standardized care to a more precise, patient-specific approach guided by molecular profiling. This evolution is being enabled by advances in liquid biopsy, multiomics, and artificial intellig...
Background: The clinical presentation of nasal mucosal necrosis, an exceedingly rare manifestation of secondary antiphospholipid syndrome (APS) in patients with systemic lupus erythematosus, often mimics invasive fungal sinusitis (IFS), causing diagn...
Background/Objectives: Pain and psychosocial distress are highly prevalent across acute and chronic medical conditions and may negatively affect quality of life, treatment adherence, and clinical outcomes. Green light therapy has emerged as a non-pha...
Background/Objectives: Hallux valgus is a common forefoot deformity whose surgical correction generally yields favorable functional outcomes. However, postoperative complications remain a clinically relevant concern, and the contribution of preoperat...
Background: Friedreich’s ataxia (FRDA) is a neurodegenerative disorder driven by frataxin deficiency, resulting in mitochondrial dysfunction and reduced nuclear factor erythroid 2-related factor 2 (Nrf2) signaling. Pharmacologic trials have yie...
Background: Surgical sepsis complicated by acute kidney injury (AKI) is associated with high mortality, and early risk stratification remains challenging. The prognostic nutritional index (PNI), derived from serum albumin and lymphocyte count, reflec...
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