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Journal of Clinical Medicine, Volume 14, Issue 11

June-1 2025 - 396 articles

Cover Story: Inflammatory arthritides (IAs) are systemic inflammatory syndromes affecting various organs. Although brain involvement has already been reported, it is considered a rare complication. In this study, we investigated the relationship between cardiac and subclinical brain involvement in patients with IAs. We consecutively evaluated 25 patients with IAs and 31 disease controls with non-autoimmune cardiovascular diseases (CVDs) reporting cardiac symptoms and 25 consecutive asymptomatic healthy controls without CVDs using combined brain/heart magnetic resonance imaging (MRI). Amongst patients with IA, increased cardiac T2 ratio, T2 mapping, and ECV were associated with an increased probability of WMH occurrence. In IA patients with cardiac symptoms, myocardial edema was associated with a greater WMH burden, potentially suggesting shared pathophysiologic substrates. View this paper
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Articles (396)

  • Article
  • Open Access
1,927 Views
14 Pages

The Hungry Heart: Managing Cardiogenic Shock in Patients with Severe Anorexia Nervosa—A Case Report Series

  • Manuela Thienel,
  • Rainer Kaiser,
  • Jonas Gmeiner,
  • Martin Orban,
  • Stefan Kääb,
  • Tobias Petzold,
  • Steffen Massberg and
  • Clemens Scherer

5 June 2025

Background: Cardiogenic shock is a life-threatening condition characterized by the failure of the heart to maintain adequate circulation, leading to multi-organ dysfunction. While it is most commonly associated with acute myocardial infarction or car...

  • Article
  • Open Access
2,539 Views
10 Pages

5 June 2025

Background/Objectives: This study assessed the reliability of the Barrett True-K formula in patients who had undergone laser-based corneal refractive surgery by comparing outcomes using measured vs. predicted posterior corneal astigmatism (PCA) withi...

  • Review
  • Open Access
3 Citations
1,447 Views
14 Pages

5 June 2025

Postoperative pain management after hospital discharge remains one of the main clinical challenges. The use of digital and telemedicine tools offers new opportunities for the continuous monitoring of, and timely intervention in, patients discharged a...

  • Case Report
  • Open Access
1,136 Views
8 Pages

5 June 2025

Background/Objectives: Horseshoe kidney is a congenital anomaly characterized by the fusion of the kidneys at the lower pole. Polycystic kidney disease with horseshoe kidney is called polycystic horseshoe kidney. Genetic testing is essential for the...

  • Article
  • Open Access
1 Citations
1,482 Views
16 Pages

Oxidative Stress and Risk Factors in Adult Patients with Bronchial Asthma: A Clinical Analysis of Representative Biomarkers

  • Oana-Elena Melinte,
  • Emanuel Ioan Stavarache,
  • Mona Elisabeta Dobrin,
  • Andrei Tudor Cernomaz,
  • Ionel-Bogdan Cioroiu,
  • Daniela Robu Popa,
  • Ionela-Alina Grosu-Creanga,
  • Andreea Zabara Antal and
  • Antigona Carmen Trofor

5 June 2025

Background: Asthma is a chronic inflammatory airway disease in which oxidative stress and antioxidant imbalance play a critical role in disease progression and therapeutic response. This study aimed to evaluate oxidative stress and antioxidant status...

  • Article
  • Open Access
1,215 Views
15 Pages

Heart Failure, Kidney Function, and Elderly Age, Rather than Levofloxacin Therapy, Are Associated with QTc Prolongation in COVID-19 Patients

  • Katarzyna Wilk-Śledziewska,
  • Rafał Śledziewski,
  • Małgorzata Gryciuk,
  • Piotr Jan Sielatycki,
  • Aleksandra Zbroch,
  • Franciszek Kukliński and
  • Edyta Zbroch

5 June 2025

Background: Prolongation of the QT interval is directly related to the risk of ventricular arrhythmias and sudden cardiac death. Age, comorbidities, and treatment schemes have been shown to influence its prolongation and may also significantly affect...

  • Article
  • Open Access
1,245 Views
12 Pages

Diagnostic Utility of Intratumoral Susceptibility Signals in Adult Diffuse Gliomas: Tumor Grade Prediction and Correlation with Molecular Markers Within the WHO CNS5 (2021) Classification

  • José Ignacio Tudela Martínez,
  • Victoria Vázquez Sáez,
  • Guillermo Carbonell,
  • Héctor Rodrigo Lara,
  • Florentina Guzmán-Aroca and
  • Juan de Dios Berna Mestre

5 June 2025

Background/Objectives: This study evaluates intratumoral susceptibility signals (ITSS) as imaging markers for glioma grade prediction and their association with molecular and histopathologic features, in the context of the fifth edition of the World...

  • Systematic Review
  • Open Access
1 Citations
2,350 Views
47 Pages

5 June 2025

Introduction: Infrazygomatic crest (IZC) miniscrews are widely used for skeletal anchorage in orthodontics. Despite their growing popularity, the optimal insertion parameters—such as height, angulation, and anatomical position—remain cont...

  • Systematic Review
  • Open Access
3 Citations
2,920 Views
15 Pages

Adjuvant Radiotherapy for Intermediate-Risk Early-Stage Cervical Cancer Post Radical Hysterectomy: A Systematic Review and Meta-Analysis

  • Pedro Henrique Costa Matos da Silva,
  • Gabriela Oliveira Gonçalves Molino,
  • Maírla Marina Ferreira Dias,
  • Ana Gabriela Alves Pereira,
  • Nicole dos Santos Pimenta,
  • Deivyd Vieira Silva Cavalcante,
  • Ana Clara Felix de Farias Santos,
  • Sarah Hasimyan Ferreira,
  • Rodrigo da Silva Santos and
  • Angela Adamski da Silva Reis

5 June 2025

Background: The risk of recurrence of early-stage cervical cancer (CC) is associated with prognostic factors such as tumor size, lymphovascular space invasion (LVSI), and deep stromal invasion (DSI). However, the adjuvant pelvic radiotherapy (RT) fol...

  • Article
  • Open Access
1,743 Views
13 Pages

Temporal Patterns of Air Leak Resolution in Secondary Spontaneous Pneumothorax: A Hazard Function Analysis for Optimal Intervention Timing

  • Ryo Takeyama,
  • Yoshikane Yamauchi,
  • Shinya Kohmaru,
  • Shizuka Morita,
  • Hikaru Takahashi,
  • Tomoki Nishida,
  • Yuichi Saito and
  • Yukinori Sakao

5 June 2025

Objectives: This study was aimed to identify risk factors for persistent air leak after chest tube placement for secondary spontaneous pneumothorax and to determine the optimal timing of treatment. Methods: We retrospectively analyzed 221 cases of se...

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J. Clin. Med. - ISSN 2077-0383