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Clinical Innovations in Dental Implant: Expanding Possibilities for Oral Rehabilitation
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Clinical Innovations in Dental Implant: Expanding Possibilities for Oral Rehabilitation

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dentistry, Oral Surgery and Oral Medicine".

Deadline for manuscript submissions: 20 December 2025 | Viewed by 646

Special Issue Editor

Dr. Marco Severino

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Guest Editor
Section of Odontostomatologic Surgery, University of Perugia, 06123 Perugia, Italy
Interests: dental; dental implant; oral rehabilitation; rehabilitations

Special Issue Information

Dear Colleagues,

This Special Issue of the Journal of Clinical Medicine, entitled ‘Clinical Innovations in Dental Implant: Expanding Possibilities for Oral Rehabilitation’, aims to explore the latest clinical innovations in the field of dental implants, which are transforming the landscape of oral rehabilitation. Emerging technologies and advanced methods are greatly expanding therapeutic possibilities, improving patient outcomes and optimising clinical protocols. The introduction of innovative materials, minimally invasive approaches, and digital design techniques has enabled more precise, durable and customised solutions.

This Special Issue features articles examining improved biocompatibility of implants, innovations in guided surgery, the use of advanced imaging technologies, and integration with regenerative treatments. It also discusses developments in strategies for managing postoperative complications and customising treatment for different clinical needs. Helping to define new frontiers in oral rehabilitation, this Special Issue offers an important opportunity for professionals to keep up to date, encouraging the continuous advancement of clinical practice in the field of dental implants.

Dr. Marco Severino
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dental implants
  • oral rehabilitation
  • computer-guided surgery
  • biocompatibility
  • regenerative treatments
  • mini-implants
  • minimally invasive surgery

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Published Papers (1 paper)

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47 pages, 2409 KiB  
Systematic Review
Optimizing Infrazygomatic Miniscrew Insertion Parameters: Systematic Review and Meta-Regression Analysis of Bone Thickness by Insertion Height, Angulation, and Anatomical Position
by Kais Hijazi Muwaquet, Susana Muwaquet Rodriguez, Marcela Ferrer Molina and Tawfiq Hijazi Alsadi
J. Clin. Med. 2025, 14(11), 4005; https://doi.org/10.3390/jcm14114005 - 5 Jun 2025
Viewed by 519
Abstract
Introduction: Infrazygomatic crest (IZC) miniscrews are widely used for skeletal anchorage in orthodontics. Despite their growing popularity, the optimal insertion parameters—such as height, angulation, and anatomical position—remain controversial, with existing studies offering inconsistent and fragmented data. Aim: To determine the optimal insertion position, [...] Read more.
Introduction: Infrazygomatic crest (IZC) miniscrews are widely used for skeletal anchorage in orthodontics. Despite their growing popularity, the optimal insertion parameters—such as height, angulation, and anatomical position—remain controversial, with existing studies offering inconsistent and fragmented data. Aim: To determine the optimal insertion position, height, and angulation of infrazygomatic miniscrews to maximize bone insertion using cone-beam computed tomography (CBCT) analysis and to investigate the influence of facial skeletal patterns on IZC bone morphology. Methods: This review was conducted according to the PRISMA 2020 guidelines. A comprehensive electronic search was performed across six databases: PubMed, Scopus, Web of Science, Cochrane, EBSCO, and Google Scholar. Studies reporting CBCT-based IZC bone thickness were included. A meta-analysis was conducted using a random-effects model, and meta-regression was applied to assess the relationship between insertion height, angulation, and bone thickness. The STROBE checklist was used to assess the quality of the included observational studies. Results: Seventeen studies comprising a total of 1840 CBCT-based measurements were included. The meta-regression revealed a significant inverse relationship between insertion height and bone thickness (β = −0.53; p < 0.001) and a positive correlation with angulation (β = 0.09; p < 0.001). The U67 region refers to the anatomical area between the maxillary first and second molars, adjacent to the infrazygomatic crest and zygomatic buttress, which with an insertion height of 9.9 mm and 80° angulation, demonstrated the highest mean cortical bone thickness (3.52 mm). There was no evidence of a significant association between facial pattern and bone thickness (p = 0.878). Conclusions: This review presents the first predictive model for IZC miniscrew placement based on meta-regression. The findings support the U67 site at 9.9 mm height and 80° angulation as the optimal insertion protocol. These data-driven guidelines provide clinicians with practical, evidence-based direction for improving miniscrew stability and minimizing complications. Full article
(This article belongs to the Special Issue Clinical Innovations in Dental Implant: Expanding Possibilities for Oral Rehabilitation)
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