Current Advances in Endodontics and Dental Traumatology

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dentistry, Oral Surgery and Oral Medicine".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 3296

Special Issue Editor


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Guest Editor
Department of Conservative Dentistry and Periodontology, LMU University Hospital, LMU Munich, Goethestr 70, D-80336 Munich, Germany
Interests: navigation in endodontics and implantology; regeneration; biocompatibility and toxicology of dental materials; antimicrobial agents; research in dental education; endodontics and traumatology in children and adolescents; autotransplantation

Special Issue Information

Dear Colleagues,

While the progress in endodontics and traumatology is remarkable, various recent treatment methods, materials, and imaging approaches await thorough evaluation to fully elucidate their benefits for patients of all ages. In particular, regenerative and minimally invasive treatment options, along with possibilities to preserve pulp tissue, may facilitate better lifelong outcomes. Research on biocompatible and effective materials—especially those with antimicrobial and anti-inflammatory properties and those concerning density and stability at the interfaces between the pulp and the respective hard tissues—is of utmost importance. Advanced in vitro models and imaging are just as crucial as well-designed clinical studies and efforts to gather big data to collaboratively gain deeper insights using artificial intelligence applications. Finally, action is needed to broaden worldwide recognition and the actual application of these specific techniques, beginning with enhanced educational efforts for undergraduate and postgraduate students.

Prof. Dr. Karin Christine Huth
Guest Editor

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Keywords

  • endodontology
  • traumatology
  • regeneration
  • biocompatibility
  • dental materials
  • antimicrobial
  • dynamic and static navigation in endodontics
  • under- and postgraduate education in endodontology and traumatology
  • artificial intelligence
  • autotransplantation

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Published Papers (6 papers)

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16 pages, 605 KiB  
Article
Maxillary Incisor Fragment Reattachment Protocols: Influence on Tooth Fracture Resistance and Strength of Bonding to Orthodontic Brackets
by Moataz Elgezawi, Rasha Haridy, Khalid S. Almulhim, Moamen A. Abdalla, Ahmed A. Alsulaiman, Laila Al Dehailan, Rasha Alsheikh, Shahad Alotaibi, Deena Alghamdi, Ohud Almutairi, Sahar F. Alwehaibi, Ala’a Kamal and Dalia Kaisarly
J. Clin. Med. 2025, 14(9), 3220; https://doi.org/10.3390/jcm14093220 - 6 May 2025
Viewed by 163
Abstract
Objectives: Trauma to maxillary incisors is frequent, and requires timely, conservative management for optimal prognosis. This in vitro study evaluated the fracture resistance (FR) and orthodontic bracket bond strength (BS) of incisors following incisal fragment reattachment using various restorative techniques. Materials and [...] Read more.
Objectives: Trauma to maxillary incisors is frequent, and requires timely, conservative management for optimal prognosis. This in vitro study evaluated the fracture resistance (FR) and orthodontic bracket bond strength (BS) of incisors following incisal fragment reattachment using various restorative techniques. Materials and Methods: Two independent tests—FR testing (Newtons) and BS testing (megapascals)—were conducted. Eighty intact human maxillary central incisors (n = 40/test), standardized in size and shape using a digital caliper (Mitutoyo, ±0.01 mm), were embedded in acrylic resin and numbered. An uncomplicated crown fracture was induced in 64 teeth (n = 32/test), and the teeth were randomly assigned (simple randomization using Excel’s RAND function) to five groups (n = 8/group/test): (1) intact teeth (negative control, NC); (2) nanohybrid composite buildup using Filtek Z250 and Single Bond 2 (positive control, CB); (3) fragment reattachment using flowable composite (Filtek Supreme, FL); (4) reattachment with a palatal veneer using a nanohybrid composite (PV); and (5) reattachment reinforced with a polyethylene fiber band (Ribbond Inc., RB). In BS testing groups, stainless steel orthodontic brackets (PINNACLE) were bonded using Transbond XT, centered over the fracture line. Light curing was performed using an LED unit (Mini LED Standard, Acteon, 1250 mW/cm2, 20 s/bond, 40 s/composite, 2 mm curing tip distance). Specimens were stored in distilled water at room temperature for 24 h before reattachment. FR and BS were evaluated using a universal testing machine (Instron) until failure. Failure modes were analyzed, and data were statistically evaluated using one-way ANOVA, Tukey’s post hoc test, and Pearson’s correlation analysis. Results: Significant differences were observed among groups for both FR and BS (p < 0.05). The NC group exhibited the highest FR (514.4 N) and BS (17.6 MPa). The RB group recorded the second-highest FR (324.6), followed by the PV (234.6), CB (224.9), and FL (203.7) groups. The CB group demonstrated the second-best BS (16.6), followed by the RB (15.2), FL (13.4), and PV (6.5) groups. FR and BS were negatively correlated. Mixed failures predominated in the reattachment groups, except for the PV group, which showed mainly adhesive failures. In BS testing, mixed failures dominated in the NC and CB groups, while adhesive failures predominated in the PV and FL groups. Conclusions: Ribbond reinforcement improves the mechanical performance of reattached incisal fragments, and composite buildup may provide more reliable bracket bonding than fragment reattachment. Clinical Relevance: In cases where biomimetic, minimally invasive reattachment is indicated, Ribbond fiber reinforcement appears to offer a reliable restorative solution. Full article
(This article belongs to the Special Issue Current Advances in Endodontics and Dental Traumatology)
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17 pages, 6079 KiB  
Article
Retrieval of AH Plus Bioceramic and Ceraseal Versus AH Plus in Endodontic Retreatment
by Eurok Shim, Jee Woo Son, Jiyoung Kwon, Hyun-Jung Kim, Ji-Hyun Jang, Seok Woo Chang and Soram Oh
J. Clin. Med. 2025, 14(6), 1826; https://doi.org/10.3390/jcm14061826 - 8 Mar 2025
Viewed by 609
Abstract
Background/Objectives: Since biomineralization by calcium silicate-based sealers (CSBSs) was reported, retrieving canal filling materials may be challenging during endodontic retreatment due to their adhesion to dentin. This study aimed to evaluate the possibility of removing residual mineral deposits from two kinds of CSBSs [...] Read more.
Background/Objectives: Since biomineralization by calcium silicate-based sealers (CSBSs) was reported, retrieving canal filling materials may be challenging during endodontic retreatment due to their adhesion to dentin. This study aimed to evaluate the possibility of removing residual mineral deposits from two kinds of CSBSs compared to the AH Plus Jet (AHJ). Methods: Root canals of mandibular premolars were prepared, obturated with the sealer-based obturation method using a WOG medium gutta-percha cone and one of the following sealers: AHJ, AH Plus Bioceramic (AHB), and Ceraseal (CER) (n = 12/group). After 3 weeks, endodontic retreatment was conducted with the WOG files, followed by instrumentation with XP-endo Finisher (XPF). Micro-computed tomography scanning was obtained after canal filling, after retreatment with WOG, and after the use of XPF. The percentage of the removed filling volume was calculated. One-way ANOVA with Tukey’s test and a non-parametric test with Bonferroni’s correction were performed. Root canal dentin after retreatment was examined using a scanning electron microscope (SEM). Results: After supplementary instrumentation with XPF, the mean residual filling volumes for the AHJ, AHB, and CER groups were 1.35 mm3, 0.55 mm3, and 0.82 mm3, respectively. The AHJ group showed greater residual volume compared to the AHB group (p < 0.05). The AHB and CER groups demonstrated higher mean percentages of removed filling volume at 94.8%, and 92.5%, respectively, compared to 87.1% for the AHJ group (p < 0.05). More mineral deposits were observed in the CER group with SEM. Conclusions: AHB and CER are retrievable during endodontic retreatment, with CER preferable due to greater mineral deposits in dentinal tubules. Full article
(This article belongs to the Special Issue Current Advances in Endodontics and Dental Traumatology)
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15 pages, 1534 KiB  
Article
Autogenous Tooth Transplantation of Canines—A Prospective Clinical Study on the Influence of Adjunctive Antibiosis and Patient-Related Risk Factors During Initial Healing
by Sebastian Meinzer, Dirk Nolte and Karin Christine Huth
J. Clin. Med. 2025, 14(3), 821; https://doi.org/10.3390/jcm14030821 - 26 Jan 2025
Viewed by 872
Abstract
Objectives: This prospective clinical study investigated the efficacy of adjunctive antibiotic therapy (doxycycline) and the patient’s risk factors during initial healing of autogenous canine tooth transplantations. Methods: Sixty-seven patients (ranging from 11 to 37 years of age) treated with tooth transplantations [...] Read more.
Objectives: This prospective clinical study investigated the efficacy of adjunctive antibiotic therapy (doxycycline) and the patient’s risk factors during initial healing of autogenous canine tooth transplantations. Methods: Sixty-seven patients (ranging from 11 to 37 years of age) treated with tooth transplantations were allocated to three parallel groups based on the tooth’s intraoperative extraoral storage time (EST 0–3, 4–6, and 7–15 min) receiving different antibiotic regimens: (1) no antibiotics; (2) intraoperative intravenous (i.v.) single-shot antibiotics; and (3) intraoperative i.v. single-shot plus postoperative oral antibiotics for five days. Initial healing was rated according to pain intensity and clinical signs of pathology over a 21-day period. The influence of the following parameters was investigated using RStudio (linear regression and partial eta squared statistics): group, sex, age, nicotine abuse, tooth apex condition, preoperative ankylosis, displacement severity, jaw location, the number of simultaneous transplantations and other interventions, preoperative orthodontic extrusion, EST, and intraoperative complications. Results: No significant influence for sex (43 females, 24 males), tooth apex condition (19 open, 48 closed), displacement severity, jaw location (51 upper, 16 lower jaw), EST (mean 4.99 min), intraoperative complications (n = 13), or antibiotic regimen on pathology signs or pain intensity were found. Six patients reported medication side effects. Preoperative ankylosis (n = 15) and unsuccessful orthodontic extrusion (n = 16) increased postoperative pain (p = 0.020, ηP2 = 0.08; p = 0.035, ηP2 = 0.07). Multiple transplants (n = 14) and interventions in multiple regions (n = 27) affected pain and pathology (p = 0.002, ηP2 = 0.14; p = 0.001, ηP2 = 0.17). Increased age and nicotine abuse (n = 6) were associated with increased pathology signs (p = 0.024, ηP2 = 0.08; p = 0.029, ηP2 = 0.07). Conclusions: The results suggest that personalized rather than routine antibiotic therapy might be sufficient for initial healing in canine tooth transplantation. Deteriorating factors include preoperative ankylosis, orthodontic extrusion, an increased number of surgical sites, age, and nicotine abuse. Clinical Significance: Routine antibiotic prevention regimes may not be mandatory for initial healing in autogenous tooth transplantation, but a nuanced antibiotic strategy tailored to each patient’s specific risk factors, which is in line with the principle of antibiotic stewardship, is needed. Full article
(This article belongs to the Special Issue Current Advances in Endodontics and Dental Traumatology)
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8 pages, 2726 KiB  
Communication
The Regensburg Dental Trauma Registry: Methodical Framework for the Systematic Collection of Dentoalveolar Trauma Data
by Matthias Widbiller, Gunnar Huppertz, Karolina Müller, Michael Koller, Torsten E. Reichert, Wolfgang Buchalla and Martyna Smeda
J. Clin. Med. 2024, 13(23), 7196; https://doi.org/10.3390/jcm13237196 - 27 Nov 2024
Viewed by 697
Abstract
Objectives: Traumatic dental injuries (TDIs) are common, particularly in children and adolescents, and require timely, well-documented treatment for optimal long-term functional and esthetic outcomes. Despite their prevalence, comprehensive data on TDI remain limited. The Regensburg Dental Trauma Registry (RDTR) was established to enable [...] Read more.
Objectives: Traumatic dental injuries (TDIs) are common, particularly in children and adolescents, and require timely, well-documented treatment for optimal long-term functional and esthetic outcomes. Despite their prevalence, comprehensive data on TDI remain limited. The Regensburg Dental Trauma Registry (RDTR) was established to enable structured data collection, documentation and analysis of dentoalveolar trauma cases to improve both research and clinical practice. Methods: The RDTR was developed at the Centre for Dental Traumatology at the University Hospital Regensburg as part of a multi-stage implementation process, which involved creating clinical infrastructure, establishing treatment protocols, providing continuous clinician training, and designing a standardized documentation form to capture essential data, including patient demographics, accident details, clinical assessments, and initial treatment. Data are transferred into a REDCap electronic case report form (eCRF), which is hosted on secure university servers, ensuring efficient administration, controlled access and high data integrity. Quality assurance measures, including automated and manual data checks and regular treatment protocol updates, maintain high data accuracy and consistency. Results: This initial methodological report outlines the systematic approach of the RDTR and its potential to generate large datasets. These will enable in-depth analyses of injury patterns, treatment effectiveness, risk factors, and more. Future expansion includes collaboration with additional university hospitals to broaden the dataset and support multi-center approaches. Conclusions: The RDTR offers a framework for consistent data collection and quality control, laying the foundation for comprehensive analyses that contribute to the development of preventive strategies and treatment protocols. Full article
(This article belongs to the Special Issue Current Advances in Endodontics and Dental Traumatology)
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10 pages, 8316 KiB  
Case Report
Long-Term Outcomes of Maxillary Alveolar Process Trauma and Primary Incisor Injury in Early Childhood: A Case Report
by Sanja Vujkov, Stojan Ivic, Bojan Petrovic, Duska Blagojevic, Isidora Neskovic, Ana Tadic and Jelena Komsic
J. Clin. Med. 2025, 14(10), 3275; https://doi.org/10.3390/jcm14103275 - 8 May 2025
Abstract
Background: Traumatic injuries to the alveolar process and primary teeth in early childhood can have long-term consequences on the development of permanent dentition and eruption pathways. Objective: This case report aims to illustrate the impact of early orofacial trauma on the [...] Read more.
Background: Traumatic injuries to the alveolar process and primary teeth in early childhood can have long-term consequences on the development of permanent dentition and eruption pathways. Objective: This case report aims to illustrate the impact of early orofacial trauma on the eruption and development of permanent maxillary incisors and to emphasize the importance of timely interdisciplinary management. Case Presentation: An 8-year-old female patient presented to a pediatric dentistry clinic with delayed eruption of the maxillary anterior permanent teeth. In contrast, her monozygotic twin sister exhibited complete eruption of all permanent anterior teeth, raising parental concern regarding a possible pathological delay. Her medical history revealed orofacial trauma at the age of two, resulting in an alveolar process fracture, avulsion of the primary maxillary left central incisor (tooth 61), and luxation of the primary maxillary right central incisor (tooth 51). A clinical examination demonstrated sufficient arch space without signs of eruption and enamel defects on tooth 52. Radiographic evaluations, including panoramic imaging and cone beam computed tomography (CBCT), confirmed the presence of impacted permanent teeth with structural anomalies suggestive of trauma-related developmental disturbances. Results: The patient underwent a multidisciplinary treatment over a three-year period involving pediatric dentistry, oral surgery, and orthodontics. Management included surgical exposure of the impacted teeth followed by orthodontic traction to guide the eruption and treatment of enamel hypoplasia. Conclusions: This case highlights the long-term consequences of early traumatic dental injuries on permanent dentition development. It underscores the necessity of early diagnosis and a coordinated interdisciplinary approach to optimize outcomes and enhance the long-term oral health and quality of life of affected individuals. Full article
(This article belongs to the Special Issue Current Advances in Endodontics and Dental Traumatology)
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15 pages, 386 KiB  
Systematic Review
The Washout Resistance of Bioactive Root-End Filling Materials—A Systematic Review
by Joanna Falkowska-Ostrowska and Włodzimierz Dura
J. Clin. Med. 2025, 14(7), 2446; https://doi.org/10.3390/jcm14072446 - 3 Apr 2025
Viewed by 327
Abstract
When performing an apicoectomy avoiding the microleakage is desired. That is why materials used for this procedure should be resistant to washout. Washout refers to the tendency of freshly prepared materials to disintegrate upon contact with fluids. Background/Objectives: The aim [...] Read more.
When performing an apicoectomy avoiding the microleakage is desired. That is why materials used for this procedure should be resistant to washout. Washout refers to the tendency of freshly prepared materials to disintegrate upon contact with fluids. Background/Objectives: The aim of this paper is to provide a literature review on the washout resistance of bioactive root-end filling materials. Methods: This systematic review was conducted following the PRISMA 2020 guidelines. International databases (PubMed, Google Scholar, ScienceDirect, and Wiley Online Library) were searched, and articles published in the last 20 years were selected for analysis. The following keywords were used “antiwashout”, “washout resistance”, “washout in dentistry”, “root-end filling materials”, “calcium silicate-based cements”, “bioceramic materials”. A total of 6 in vitro studies that met all the inclusion criteria were included in the analysis. The overall risk of bias was low in all six studies. Results: Most tested bioceramic materials are Endocem, Capasio, and Ceramicrete-D. Generex-A, MTA-Plus, MTA-AW, Bioaggregate, and MTA HP usually demonstrate very good washout resistance. ProRoot and MTA Angelus performed differently depending on the test; however, generally they showed good washout resistance. The Biodentine material showed significant washout, and requires further research. There is still a lack of a unified method for washout evaluation in dentistry, which makes it difficult to compare different studies. Conclusions: The study the confirmed excellent washout resistance of EndoCem, Capasio, Ceramicrete-D, Generex-A, Bioaggregate, MTA-Plus, and MTA HP. ProRoot, MTA-Angelus, and MTA Angelus White exhibited lower washout resistance. Biodentine shows poor washout resistance, and requires further research. A unified method for assessing washout would be beneficial for comparing different studies. Full article
(This article belongs to the Special Issue Current Advances in Endodontics and Dental Traumatology)
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