- 3.4Impact Factor
- 9.9CiteScore
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Vaccines, Volume 13, Issue 6
June 2025 - 114 articles
Cover Story: Chlamydia abortus is a major bacterial pathogen of sheep worldwide, causing the death of lambs in utero. Current live vaccines have safety issues, causing disease in some animals. A new, safer and efficacious vaccine has been developed that cannot cause disease, and reduces the shedding of the pathogen in vaginal excretions following parturition, thus limiting potential transmission to other animals. The vaccine is based on a preparation of the outer membrane of the bacteria and has been optimised to determine an appropriate dose that can be delivered in a single inoculation to sheep. In the study reported here, the vaccine has been optimised further by comparing the effects of different adjuvants on its protective efficacy in order to identify the best adjuvant to include in the final formulation for commercialisation. View this paper
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Vaccines - ISSN 2076-393X