Advance in Nanoparticles as Vaccine Adjuvants

Dear Colleagues,  

Remarkable efforts have been made to develop new and improved vaccines attending antigen’s nature and immune mechanisms involved. To obtain an appropriate humoral and cell-mediated immunity, risk-free and effective vaccines are needed against infectious diseases and tumoral processes. In the last years, nanoparticles have gained much interest in new vaccines generation since they can protect the antigen targets from premature proteolytic degradation, lead to a homogeneous uptake of antigens by immune cells, and facilitating their processing and presentation. Nanoparticles composed of lipids, proteins, metals or polymers have already been used to attain some of these attributes.  This special issue aims to collect recent original research and reviews on nanoparticulate-loaded vaccines attain their nature, formulation, delivery, their safe and efficacy, and induced immune responses to accomplish efficient and long-lasting protection against infectious diseases and tumors. I look forward to receiving your contributions. 

Dr. Eduardo Gomez-Casado
Dr. Sohrab Ahmadivand
Guest Editors

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