Table of Contents
Microorganisms, Volume 7, Issue 6 (June 2019)
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Cover Story (view full-size image) The human gut is inhabited by overcrowded prokaryotic communities, a major component of which is [...] Read more. The human gut is inhabited by overcrowded prokaryotic communities, a major component of which is the virome, comprising viruses, bacteriophages, archaea, eukaryotes, and bacteria. The phageome is required for luminal homeostasis and, by their lytic or synergic capacities, can regulate the microbial community structure and activity. Dysbiosis is associated with numerous chronic human diseases, and enteric viral abnormal prints are just starting to emerge. Because the virome can impact microbial genetics and behavior, understanding its biology, composition, cellular cycle, regulation, mode of action, and potential beneficial or hostile activities can change the present paradigm of cross-talks in the luminal gut compartment. Celiac disease is a common autoimmune disease in which viruses are suggested to play a role in disease development. View this paper.