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Comparing the Metabolic Capabilities of Bacteria in the Mycobacterium tuberculosis Complex

Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14850, USA
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Microorganisms 2019, 7(6), 177; https://doi.org/10.3390/microorganisms7060177
Received: 9 May 2019 / Revised: 10 June 2019 / Accepted: 15 June 2019 / Published: 18 June 2019
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Abstract

Pathogenic mycobacteria are known for their ability to maintain persistent infections in various mammals. The canonical pathogen in this genus is Mycobacterium tuberculosis and this bacterium is particularly successful at surviving and replicating within macrophages. Here, we will highlight the metabolic processes that M. tuberculosis employs during infection in macrophages and compare these findings with what is understood for other pathogens in the M. tuberculosis complex. View Full-Text
Keywords: Mycobacterium tuberculosis complex; carbon metabolism; macrophages; tuberculosis; cholesterol; fatty acids Mycobacterium tuberculosis complex; carbon metabolism; macrophages; tuberculosis; cholesterol; fatty acids
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Fieweger, R.A.; Wilburn, K.M.; VanderVen, B.C. Comparing the Metabolic Capabilities of Bacteria in the Mycobacterium tuberculosis Complex. Microorganisms 2019, 7, 177.

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