Microorganisms, Volume 13, Issue 12

Oral candidiasis, mainly from Candida albicans, affects immunocompromised individuals, the elderly, and denture wearers. Probiotics offer immunomodulatory and microbiota-balancing benefits as potential antifungal alternatives. However, the comparativ...

Understanding the drivers of average daily gain (ADG) is key to enhancing the productivity of Tan sheep. This study employed an integrated multi-omics approach to compare rumen microbial communities (16S rRNA sequencing) and metabolomic profiles betw...

Diabetes mellitus is a common endocrine disorder in dogs and cats, and achieving stabilization with insulin alone can be challenging. This study evaluated the glucose-lowering efficacy and safety of Bifidobacterium longum CKD1 in diabetic companion a...

The gastrointestinal microbiota of ruminants constitutes a complex invisible organ, which converts plant fibers into volatile fatty acids (VFAs) and microbial protein through fermentation, serving as the primary energy and protein sources for the hos...

The fungus Penicillium digitatum causes citrus green mold, a major postharvest disease. Understanding the molecular mechanisms underlying its development is crucial for devising effective control strategies. In this study, we performed a comprehensiv...

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Monascus pigments (MPs) are valuable natural colorants, but their industrial production is often hampered by scarce high-yield strains and inefficient processes. In this study, a novel MPs-producing strain was isolated from red yeast rice and named a...

Ballast water (BW) is a major pathway for the spread of invasive microorganisms and pathogens, posing significant ecological and public health risks. The International Maritime Organization (IMO) has established strict discharge standards, yet routin...

Anthracnose is one of the major diseases affecting Dalbergia odorifera T. Chen. However, the soil microbial mechanisms underlying D. odorifera responses to anthracnose remain largely unexplored. This study investigated three planting systems: a Dalbe...

Natural humus, characterized by its high organic carbon content and high degree of humification, is widely used in soil improvement. However, the impact of natural humus on the multifunctionality of saline–alkali soils and its relationship with...

Plant diseases caused by a wide range of pathogens—including fungi, bacteria, viruses, and fungus-like organisms (oomycetes)—represent one of the most significant threats to global food security, agricultural sustainability, and ecosystem...

Brucella are intracellular pathogens that use flexible respiratory strategies to adapt to oxygen-limited conditions. The nor operon encodes components of nitric oxide reductase (Nor), which are involved in denitrification and nitric oxide (NO) detoxi...

The endophytic Streptomyces sp. PRh3 (PRh3), isolated from Dongxiang wild rice (DXWR), exhibited impaired biosynthetic capacity in the laboratory. To address this defect, rifampicin-based ribosome engineering was first applied to PRh3 to generate PRh...

Soil microbial carbon use efficiency (CUE) is the core of the soil carbon (C) cycle that captures a dual microbial control point between soil organic C (SOC) accumulation and loss. The interpretation of these patterns and drivers of microbial CUE aft...

The seasonal freeze–thaw cycle induces a fundamental regime shift in lake ecosystems, primarily through the restructuring of microbial communities. This study investigated the dynamics and mechanisms of species diversity maintenance in protista...

Japanese encephalitis (JE) caused by Japanese encephalitis virus (JEV) is a dominant arthropod-borne disease in Asian countries. However, effective antiviral treatment for JEV has not yet been established. 2H4 is a previously identified mouse monoclo...

Extreme hypersaline environments harbour a unique biodiversity capable of surviving in such habitats, including halophilic and halotolerant bacteria. Microbial adaptations to these environments comprehend two main strategies: the “salt-in&rdquo...

No vaccines are licensed against enterotoxigenic Escherichia coli (ETEC), a leading diarrheal cause in children and travelers. ETEC adhesins and enterotoxins are the virulence determinants and become the primary targets in ETEC vaccine development. H...

Congenital toxoplasmosis presents with a wide clinical spectrum, ranging from asymptomatic infection to severe disease with multi-organ failure. We report a rare fatal case of disseminated congenital toxoplasmosis in a human neonate. The infant initi...

Inflammatory bowel diseases (IBDs), including Crohn’s disease and ulcerative colitis (UC), are characterized by chronic gastrointestinal inflammation and involve complex interactions of genetic, environmental, and immune factors. Enterococcus f...

Aeromonas salmonicida is a major pathogen in aquaculture, and its ability to form biofilms contributes significantly to antibiotic resistance and chronic infections. This study investigated the effects of four antibiotics—ampicillin, amoxicilli...

Ticks transmit diverse pathogens, posing significant public health threats in northeastern China; clarifying human-biting tick species and their carried pathogens is crucial for risk assessment and prevention. This study was designed as a pathogen de...

The research employed Caenorhabditis elegans to compare the anti-infection and lifespan-extending properties of Bifidobacterium. The results demonstrated that BL-99 and YLGB-1496 intervention improved the nematodes’ resistance to Staphylococcus...

Desertification poses a severe challenge in China. Although long-term sand control measures have proven effective, the extensive and challenging nature of sandy land necessitates systematic research to identify optimal sand control measures for soil...

In the original publication [...]

Purpureocillium lilacinum is an emerging pathogen that can cause severe ocular infections. This study aimed to investigate the risk factors, clinical manifestations, antifungal susceptibilities, and outcomes of ocular infections caused by P. lilacinu...

Lead and zinc pollution is a prevalent issue in agricultural soils surrounding lead and zinc mines, posing a serious risk to crop growth and soil health. Heavy metal-resistant, plant growth-promoting bacteria (PGPB) capable of supporting plant develo...

Fungal aerosols are critical yet understudied bioaerosol components in enclosed poultry environments, particularly during winter when ventilation is restricted. This study investigated stage-specific variations in fungal aerosol concentration, size d...

Fertilization is an effective measure to rapidly improve soil quality in reclaimed mining areas. However, the combined effects of fertilization regimes and reclamation age on phosphorus (P) fraction transformation and the pqqC-harboring microbial com...

Probe-based capture represents a highly sensitive and cost-effective approach for overcoming host background and enriching viruses in metagenomic NGS (mNGS) libraries. Using clinical specimens collected globally from patients with fever or respirator...

Tuberculosis remains one of the most prevalent infectious diseases, and the only currently available vaccine is the Mycobacterium bovis bacillus Calmette–Guèrin (BCG) vaccine. The uncontrolled passaging of the BCG strain led to genetical...

The soil-borne fungus Verticillium dahliae is a devastating pathogen responsible for substantial losses in cotton production. This study elucidated the key functions of VdARO2 and VdCPC1 in fungal pathogenicity. VdARO2 encodes a Chalmoic acid synthas...

Human West Nile virus (WNV) infections can have severe neurological health effects, especially among those over 50 years of age. As changes in weather patterns lead to more frequent and intense droughts, there is a public health need for improved und...

The aim of this study was to investigate differences in the dynamics of ochratoxin A (OTA) production by various Aspergillus isolates under different cultivation conditions. Nine strains representing A. westerdijkiae, A. ochraceus, A. sulphureus, A. ...

Human infections caused by pathogenic bacteria remain a major global health concern. Among them, Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, and Salmonella typhi are particularly prevalent and associated with significant morbidity...

Klebsiella pneumoniae (K. pneumoniae) is an opportunistic bacteria that can result in severe liver abscesses, pulmonary damage, and potentially fatal outcomes. Research has demonstrated that the outer membrane vesicles (OMVs) released by it can provi...

Biological soil amendments of animal origin (BSAAOs) provide risk for foodborne contamination. Soils are often enriched with BSAAOs to increase nutrient value, enhance and support crop growth and yield. Little is known about the interactions of soil...

Type I-E and I-F CRISPR-Cas systems were identified in 237 E. coli strains isolated from patients with urinary tract infections (UTIs) between 2004 and 2019. The strains were classified into nine distinct groups (I–IX) based on the presence or...

Resveratrol (RES), a natural polyphenol, and β-hydroxy-β-methylbutyric acid (HMB), a key metabolite of leucine, are emerging as potent feed additives in animal production. This study investigated the individual and combined effects of dieta...

Soil microbial communities face the combined pressures of climate change and biodiversity loss, yet how these stressors interact to shape ecosystem function remains a critical uncertainty. To investigate this, we established a constructed grassland p...

Peganum harmala (L.) Schrad., a perennial medicinal plant thriving in arid Moroccan soils, represents a natural reservoir of unexplored bacterial diversity. To uncover its hidden foliar endosphere microbiota, we isolated and characterized two Acineto...

To tackle grape branch and leaf waste and alleviate global feed shortages, this study tested silage made from Xinjiang ‘Seedless White’ grape foliage. Three treatments were established: CK (control, only grape branches and leaves), PL (in...

Fertilization plays a vital role in replenishing soil nutrients, shaping microbial community composition, and enhancing agricultural productivity. Castor bean cake (CBC) is a nitrogen- and carbon-rich by-product increasingly used as an organic amendm...

The gut microbiota forms early in life and undergoes dynamic changes that are essential for host health and development. Although body condition is a key fitness-related trait and predictor of viability in many animal species, its association with gu...

Olive anthracnose is a major disease worldwide; although once chiefly attributed to Colletotrichum acutatum, it is now clear that the predominant pathogen varies among regions. In this study, we identified Colletotrichum scovillei for the first time...

The 21st century calls for a paradigm shift in agricultural practices to address the pressing issues of regeneration of soil health, climate change, environmental degradation, sustainability under growing population pressures, and food security chall...

Deep tissue infection is a serious complication following operative fixation of pilon fractures, yet the influence of intraoperative factors and microbial characteristics remains underexplored. In this retrospective review of 123 patients treated wit...

Grape harvest time influences the berry composition, which impacts the organoleptic wine characteristics. Winemakers monitor technological, phenolic, and aromatic grape maturity to decide the harvest date. Little is known about the evolution of yeast...

Arcobacter butzleri and Arcobacter cryaerophilus are emerging foodborne and waterborne pathogens associated with enteritis and extraintestinal infections in humans. Their persistence in the environment and resistance to antimicrobial treatment are cl...

Yeast culture (YC) is a microbial product that enhances ruminal fiber breakdown and improves nutrient digestion and utilization. Our previous research showed that oxalic acid (OA) is a crucial metabolite in YC that enhances rumen function. This study...