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Micromachines, Volume 9, Issue 3 (March 2018)
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Cover Story (view full-size image) Circulating tumor cells (CTCs) are regarded as a strong biomarker which includes clinically [...] Read more. Circulating tumor cells (CTCs) are regarded as a strong biomarker which includes clinically valuable information. However, CTCs are very rare and require precise separation and detection for effective clinical applications. In this paper, we report a flow-restricted microfluidic trap array capable of deterministic single-cell capture of CTCs. The single-CTC capturing ability not only showed cell enumerating ability but also high prospects for application in future automated downstream analysis. View this paper