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Micromachines, Volume 9, Issue 3

March 2018 - 47 articles

Cover Story: Circulating tumor cells (CTCs) are regarded as a strong biomarker which includes clinically valuable information. However, CTCs are very rare and require precise separation and detection for effective clinical applications. In this paper, we report a flow-restricted microfluidic trap array capable of deterministic single-cell capture of CTCs. The single-CTC capturing ability not only showed cell enumerating ability but also high prospects for application in future automated downstream analysis. View this paper
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Articles (47)

  • Article
  • Open Access
17 Citations
6,611 Views
11 Pages

Dielectrophoretic Microfluidic Device for in Vitro Fertilization

  • Hong-Yuan Huang,
  • Yun-Li Lai and
  • Da-Jeng Yao

20 March 2018

The aim of this work was to create a microfluidic platform that uses in vitro fertilization (IVF) and avoids unnecessary damage to oocytes due to the dielectrophoretic force manipulation of the sperms and oocytes that occurs in a traditional IVF oper...

  • Review
  • Open Access
24 Citations
6,560 Views
10 Pages

Optofluidics Refractometers

  • Cheng Li,
  • Gang Bai,
  • Yunxiao Zhang,
  • Min Zhang and
  • Aoqun Jian

20 March 2018

Refractometry is a classic analytical method in analytical chemistry and biosensing. By integrating advanced micro- and nano-optical systems with well-developed microfluidics technology, optofluidics are shown to be a powerful, smart and universal pl...

  • Article
  • Open Access
14 Citations
4,703 Views
15 Pages

20 March 2018

This paper presents an optimization-based design method of passive micromixers for immiscible fluids, which means that the Peclet number infinitely large. Based on topology optimization method, an optimization model is constructed to find the optimal...

  • Feature Paper
  • Article
  • Open Access
8 Citations
5,924 Views
9 Pages

20 March 2018

Through via holes in fused silica are a key infrastructure element of microwave and millimeter-wave circuits and 3D integration. In this work, etching through via holes in ultra-thin fused silica wafers using deep reactive-ion etching (DRIE) and lase...

  • Article
  • Open Access
27 Citations
7,401 Views
10 Pages

Single-Wall Carbon Nanotube-Coated Cotton Yarn for Electrocardiography Transmission

  • Yuliang Zhao,
  • Yuying Cao,
  • Junshan Liu,
  • Zhikun Zhan,
  • Xiaoli Li and
  • Wen Jung Li

19 March 2018

We fabricated a type of conductive fabric, specifically single-wall carbon nanotube-coated cotton yarns (SWNT-CYs), for electrocardiography (ECG) signal transmission utilizing a “dipping and drying” method. The conductive cotton yarns were prepared b...

  • Article
  • Open Access
12 Citations
4,689 Views
9 Pages

Fabrication and Study of Micro Monolithic Tungsten Ball Tips for Micro/Nano-CMM Probes

  • Ruijun Li,
  • Chen Chen,
  • Kuangchao Fan,
  • Zhiwei Wang,
  • Fangfang Liu and
  • Qiangxian Huang

19 March 2018

Micro ball tips with high precision, small diameter, and high stiffness stems are required to measure microstructures with high aspect ratio. Existing ball tips cannot meet such demands because of their weak qualities. This study used an arc-discharg...

  • Article
  • Open Access
5 Citations
4,804 Views
13 Pages

Modeling and Analysis of an Opto-Fluidic Sensor for Lab-on-a-Chip Applications

  • Venkatesha Muniswamy,
  • Chaya Bangalore Muniraju,
  • Prasant Kumar Pattnaik and
  • Narayan Krishnaswamy

19 March 2018

In this work modeling and analysis of an integrated opto-fluidic sensor, with a focus on achievement of single mode optical confinement and continuous flow of microparticles in the microfluidic channel for lab-on-a-chip (LOC) sensing application is p...

  • Article
  • Open Access
15 Citations
8,197 Views
14 Pages

16 March 2018

Bidirectional neural interfaces for multi-channel, high-density recording and electrical stimulation of neural activity in the central nervous system are fundamental tools for neuroscience and medical applications. Especially for clinical use, these...

  • Article
  • Open Access
20 Citations
5,114 Views
15 Pages

A Label Free Disposable Device for Rapid Isolation of Rare Tumor Cells from Blood by Ultrasounds

  • Itziar González,
  • Julie Earl,
  • Luis J. Fernández,
  • Bruno Sainz,
  • Alberto Pinto,
  • Rosa Monge,
  • Sonia Alcalá,
  • Adela Castillejo,
  • Jose L. Soto and
  • Alfredo Carrato

15 March 2018

The use of blood samples as liquid biopsy is a label-free method for cancer diagnosis that offers benefits over traditional invasive biopsy techniques. Cell sorting by acoustic waves offers a means to separate rare cells from blood samples based on t...

  • Article
  • Open Access
15 Citations
5,218 Views
8 Pages

15 March 2018

For the MEMS capacitive accelerometer, parasitic capacitance is a serious problem. Its mismatch will deteriorate the performance of accelerometer. Obtaining the mismatch of the parasitic capacitance precisely is helpful for improving the performance...

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Micromachines - ISSN 2072-666XCreative Common CC BY license