Toxins, Volume 11, Issue 5 (May 2019) – 66 articles
Cover Story (view full-size image): The cover depicts the mode of interaction (highlighted in red color) of ricin A chain (RTA) (green color) with eukaryotic large ribosomal subunit (cryo-EM structure, blue color) to access the conserved sarcin/ricin loop (SRL) and remove a single adenine base, which blocks GTP hydrolysis and impedes the function of the translational machinery. This model demonstrates the evolutionary success of the plant toxin in winning the battle to access the GTPase-associated center—the energetic heart of the ribosome—and hijacking the ribosome P-stalk, which is regarded as a landing platform for translational GTPases. View this paper.
- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
- You may sign up for e-mail alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.