Next Article in Journal
Fusarium Mycotoxins Stability during the Malting and Brewing Processes
Next Article in Special Issue
NMR-Based Metabolic Profiles of Intact Zebrafish Embryos Exposed to Aflatoxin B1 Recapitulates Hepatotoxicity and Supports Possible Neurotoxicity
Previous Article in Journal
Varanid Lizard Venoms Disrupt the Clotting Ability of Human Fibrinogen through Destructive Cleavage
Previous Article in Special Issue
Occurrence and Risk Assessment of Mycotoxins through Polish Beer Consumption
Open AccessArticle

Hydrophobized Reversed-Phase Adsorbent for Protection of Dairy Cattle against Lipophilic Toxins from Diet. Efficiensy In Vitro and In Vivo

Research and Production Center “Fox & Co” Ltd.; 117149, Simferopol Boulevard, 8, 117149 Moscow, Russia
*
Author to whom correspondence should be addressed.
Toxins 2019, 11(5), 256; https://doi.org/10.3390/toxins11050256
Received: 22 March 2019 / Revised: 29 April 2019 / Accepted: 30 April 2019 / Published: 7 May 2019
(This article belongs to the Special Issue Fungal Infestations in Humans, Animals, Crops)
The steady growth of inflammatory diseases of the udder in dairy cattle forces us to look for the causes of this phenomenon in the context of growing chemical pollution of the environment and feeds. Within the framework of this concept, an analysis was made of the polarity level of the three toxic impurity groups, which are commonly present in dairy cattle feeds. These impurities are presented by mycotoxins, polyaromatic hydrocarbons (PAH) and persistent organic pollutants (POP). It has been determined that 46% of studied mycotoxins (n = 1500) and 100% of studied polyaromatic hydrocarbons (n = 45) and persistent organic pollutants (n = 55) are lipophilic compounds, prone to bioaccumulation. A comparative evaluation of the sorption capacity of four adsorbents of a different nature and polarity with respect to the simplest PAH, naphthalene and lipophilic estrogenic mycotoxin, zearalenone in vitro has been carried out. The highest efficiency in these experiments was demonstrated by the reversed-phase polyoctylated polysilicate hydrogel (POPSH). The use of POPSH in a herd of lactating cows significantly reduced the transfer of aldrin, dieldrin and heptachlor, typical POPs from the “dirty dozen”, to the milk. The relevance of protecting the main functional systems of animals from the damaging effects of lipophilic toxins from feeds using non-polar adsorbents, and the concept of evaluating the effectiveness of various feed adsorbents for dairy cattle by their influence on the somatic cell count in the collected milk are discussed. View Full-Text
Keywords: mycotoxin; PAH; POP; lipophilicity; Log P; cattle; mastitis; ryegrass staggers; adsorbent; bioaccumulation mycotoxin; PAH; POP; lipophilicity; Log P; cattle; mastitis; ryegrass staggers; adsorbent; bioaccumulation
Show Figures

Figure 1

MDPI and ACS Style

Sotnichenko, A.; Pantsov, E.; Shinkarev, D.; Okhanov, V. Hydrophobized Reversed-Phase Adsorbent for Protection of Dairy Cattle against Lipophilic Toxins from Diet. Efficiensy In Vitro and In Vivo. Toxins 2019, 11, 256.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop