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Marine Drugs, Volume 19, Issue 3

March 2021 - 58 articles

Cover Story: The use of innovative analytical methodology led to the discovery of a new marine-derived fungal natural product N-amino-L-proline methyl ester, which revealed an exquisite and unexpected molecular choreography between a cryptic natural product and media components and structurally unprecedented artifacts that hitherto successfully masqueraded as natural products. This revelation calls into question and prompts caution when attributing the natural product, artifact, media compounents, and/or contaminant status of compounds isolated from natural extracts. View this paper.
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Articles (58)

  • Article
  • Open Access
11 Citations
3,701 Views
21 Pages

Antiproliferative Properties of Scandium Exopolysaccharide Complexes on Several Cancer Cell Lines

  • Javier Muñoz-Garcia,
  • Mattia Mazza,
  • Cyrille Alliot,
  • Corinne Sinquin,
  • Sylvia Colliec-Jouault,
  • Dominique Heymann and
  • Sandrine Huclier-Markai

23 March 2021

Antimetastatic properties on both murine and human osteosarcoma cell lines (POS-1 and KHOS) have been evidenced using exopolysaccharide (EPS) derivatives, produced by Alteromonas infernus bacterium. These derivatives had no significant effect on the...

  • Article
  • Open Access
32 Citations
5,041 Views
21 Pages

23 March 2021

This study was aimed to evaluate the efficiency of Sargassumpolycystum and nucleotides- supplemented diets to improve immune response and cold-tolerance of juvenile Litopenaeus vannamei. Four treatments were evaluated: T1, the control, shrimp receive...

  • Article
  • Open Access
28 Citations
5,109 Views
15 Pages

23 March 2021

Crustin is a type of antimicrobial peptide and plays an important role in the innate immunity of arthropods. We report here the identification and characterization of a crustin (named Crus1) from the shrimp Rimicaris sp. inhabiting the deep-sea hydro...

  • Article
  • Open Access
26 Citations
4,636 Views
18 Pages

Affinity Purification of Angiotensin Converting Enzyme Inhibitory Peptides from Wakame (Undaria Pinnatifida) Using Immobilized ACE on Magnetic Metal Organic Frameworks

  • Xuezhen Feng,
  • Dankui Liao,
  • Lixia Sun,
  • Shanguang Wu,
  • Ping Lan,
  • Zefen Wang,
  • Chunzhi Li,
  • Qian Zhou,
  • Yuan Lu and
  • Xiongdiao Lan

23 March 2021

Angiotensin-I-converting enzyme (ACE) inhibitory peptides derived from marine organism have shown a blood pressure lowering effect with no side effects. A new affinity medium of Fe3O4@ZIF-90 immobilized ACE (Fe3O4@ZIF-90-ACE) was prepared and used in...

  • Article
  • Open Access
19 Citations
4,316 Views
15 Pages

A Metataxonomic Approach Reveals Diversified Bacterial Communities in Antarctic Sponges

  • Nadia Ruocco,
  • Roberta Esposito,
  • Marco Bertolino,
  • Gianluca Zazo,
  • Michele Sonnessa,
  • Federico Andreani,
  • Daniela Coppola,
  • Daniela Giordano,
  • Genoveffa Nuzzo and
  • Chiara Lauritano
  • + 4 authors

22 March 2021

Marine sponges commonly host a repertoire of bacterial-associated organisms, which significantly contribute to their health and survival by producing several anti-predatory molecules. Many of these compounds are produced by sponge-associated bacteria...

  • Article
  • Open Access
26 Citations
4,133 Views
9 Pages

New Polyketides from the Antarctic Fungus Pseudogymnoascus sp. HSX2#-11

  • Ting Shi,
  • Yan-Yan Yu,
  • Jia-Jia Dai,
  • Yi-Ting Zhang,
  • Wen-Peng Hu,
  • Li Zheng and
  • Da-Yong Shi

22 March 2021

The species Pseudogymnoascus is known as a psychrophilic pathogenic fungus with a ubiquitous distribution in Antarctica. Meanwhile, the study of its secondary metabolites is infrequent. Systematic research of the metabolites of the fungus Pseudogymno...

  • Article
  • Open Access
29 Citations
3,672 Views
12 Pages

22 March 2021

While electrospun chitosan membranes modified to retain nanofibrous morphology have shown promise for use in guided bone regeneration applications in in vitro and in vivo studies, their mechanical tear strengths are lower than commercial collagen mem...

  • Article
  • Open Access
8 Citations
3,441 Views
17 Pages

Stereochemical Determination of Fistularins Isolated from the Marine Sponge Ecionemia acervus and Their Regulatory Effect on Intestinal Inflammation

  • Yeong Kwang Ji,
  • Seon Min Lee,
  • Na-Hyun Kim,
  • Nguyen Van Tu,
  • Yun Na Kim,
  • Jeong Doo Heo,
  • Eun Ju Jeong and
  • Jung-Rae Rho

22 March 2021

By activity-guided fractionation based on inhibition of nitric oxide (NO) and prostaglandin E2 (PGE2), six fistularin compounds (1–6) were isolated from the marine sponge Ecionemia acervus (order Astrophorida). Based on stereochemical structure deter...

  • Article
  • Open Access
29 Citations
4,344 Views
17 Pages

EPS364, a Novel Deep-Sea Bacterial Exopolysaccharide, Inhibits Liver Cancer Cell Growth and Adhesion

  • Yun Wang,
  • Ge Liu,
  • Rui Liu,
  • Maosheng Wei,
  • Jinxiang Zhang and
  • Chaomin Sun

22 March 2021

The prognosis of liver cancer was inferior among tumors. New medicine treatments are urgently needed. In this study, a novel exopolysaccharide EPS364 was purified from Vibrio alginolyticus 364, which was isolated from a deep-sea cold seep of the Sout...

  • Review
  • Open Access
74 Citations
14,785 Views
28 Pages

Anti-Photoaging and Potential Skin Health Benefits of Seaweeds

  • Ratih Pangestuti,
  • Kyung-Hoon Shin and
  • Se-Kwon Kim

22 March 2021

The skin health benefits of seaweeds have been known since time immemorial. They are known as potential renewable sources of bioactive metabolites that have unique structural and functional features compared to their terrestrial counterparts. In addi...

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Mar. Drugs - ISSN 1660-3397