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Review

Cosmetic, Biomedical and Pharmaceutical Applications of Fish Gelatin/Hydrolysates

Department of Pharmaceutical Technology, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan
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Author to whom correspondence should be addressed.
Academic Editors: Chun-Yung Huang and Yong-Han Hong
Mar. Drugs 2021, 19(3), 145; https://doi.org/10.3390/md19030145
Received: 21 January 2021 / Revised: 27 February 2021 / Accepted: 1 March 2021 / Published: 8 March 2021
There are several reviews that separately cover different aspects of fish gelatin including its preparation, characteristics, modifications, and applications. Its packaging application in food industry is extensively covered but other applications are not covered or covered alongside with those of collagen. This review is comprehensive, specific to fish gelatin/hydrolysate and cites recent research. It covers cosmetic applications, intrinsic activities, and biomedical applications in wound dressing and wound healing, gene therapy, tissue engineering, implants, and bone substitutes. It also covers its pharmaceutical applications including manufacturing of capsules, coating of microparticles/oils, coating of tablets, stabilization of emulsions and drug delivery (microspheres, nanospheres, scaffolds, microneedles, and hydrogels). The main outcomes are that fish gelatin is immunologically safe, protects from the possibility of transmission of bovine spongiform encephalopathy and foot and mouth diseases, has an economic and environmental benefits, and may be suitable for those that practice religious-based food restrictions, i.e., people of Muslim, Jewish and Hindu faiths. It has unique rheological properties, making it more suitable for certain applications than mammalian gelatins. It can be easily modified to enhance its mechanical properties. However, extensive research is still needed to characterize gelatin hydrolysates, elucidate the Structure Activity Relationship (SAR), and formulate them into dosage forms. Additionally, expansion into cosmetic applications and drug delivery is needed. View Full-Text
Keywords: fish gelatin/hydrolysate; sources; extraction; properties; cosmetic applications; pharmaceutical applications; biomedical applications fish gelatin/hydrolysate; sources; extraction; properties; cosmetic applications; pharmaceutical applications; biomedical applications
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MDPI and ACS Style

Al-Nimry, S.; Dayah, A.A.; Hasan, I.; Daghmash, R. Cosmetic, Biomedical and Pharmaceutical Applications of Fish Gelatin/Hydrolysates. Mar. Drugs 2021, 19, 145. https://doi.org/10.3390/md19030145

AMA Style

Al-Nimry S, Dayah AA, Hasan I, Daghmash R. Cosmetic, Biomedical and Pharmaceutical Applications of Fish Gelatin/Hydrolysates. Marine Drugs. 2021; 19(3):145. https://doi.org/10.3390/md19030145

Chicago/Turabian Style

Al-Nimry, Suhair, Alaa A. Dayah, Inas Hasan, and Rawand Daghmash. 2021. "Cosmetic, Biomedical and Pharmaceutical Applications of Fish Gelatin/Hydrolysates" Marine Drugs 19, no. 3: 145. https://doi.org/10.3390/md19030145

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