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19 Results Found

  • Article
  • Open Access
17 Citations
3,619 Views
15 Pages

Effects of sn-2 Palmitic Triacylglycerols and the Ratio of OPL to OPO in Human Milk Fat Substitute on Metabolic Regulation in Sprague-Dawley Rats

  • Lin Zhu,
  • Shuaizhen Fang,
  • Yaqiong Zhang,
  • Xiangjun Sun and ,
  • Puyu Yang,
  • Weiying Lu and
  • Liangli Yu
  • + 2 authors+ 0 author

26 April 2024

In this study, the influence of total sn-2 palmitic triacylglycerols (TAGs) and ratio of 1-oleoyl-2-palmitoyl-3-linoleoylglycerol (OPL) to 1,3-dioleoyl-2-palmitoylglycerol (OPO) in human milk fat substitute (HMFS) on the metabolic changes were invest...

(This article belongs to the Section Phytochemicals and Human Health)
  • Article
  • Open Access
14 Citations
5,886 Views
14 Pages

A Novel Infant Formula with Medium- and Long-Chain Triacylglycerols and sn-2 Palmitate Supports Adequate Growth and Lipid Absorption in Healthy Term Infants

  • Xiaoyan Chen,
  • Mengtao Yang,
  • Wei Wei,
  • Siyu Huang and ,
  • Yingzhen Qiu,
  • Zhen Li,
  • Qiuye Lan,
  • Bixia Huang,
  • Tong Wu and
  • Huilian Zhu
  • + 7 authors+ 2 authors

22 April 2025

Background: Medium- and long-chain triacylglycerols (MLCTs) and sn-2 palmitate constitute approximately 70~80% of total breast milk fat. The structured lipid MLCTs and sn-2 palmitate, mimicking human milk, have demonstrated improvement in lipid absor...

(This article belongs to the Special Issue Maternal Nutrition during Preconception, Pregnancy, and Lactation and Its Impact on Offspring Health)
  • Article
  • Open Access
19 Citations
3,815 Views
15 Pages

Total Sn-2 Palmitic Triacylglycerols and the Ratio of OPL to OPO in Human Milk Fat Substitute Modulated Bile Acid Metabolism and Intestinal Microbiota Composition in Rats

  • Lin Zhu,
  • Shuaizhen Fang,
  • Hong Zhang,
  • Xiangjun Sun and ,
  • Puyu Yang,
  • Jianchun Wan,
  • Yaqiong Zhang,
  • Weiying Lu and
  • Liangli Yu
  • + 4 authors+ 0 author

26 November 2023

In this study, the impact of sn-2 palmitic triacyclglycerols (TAGs) in combination with their ratio of two major TAGs (1-oleoyl-2-palmitoyl-3-linoleoylglycerol (OPL) to 1,3-dioleoyl-2-palmitoylglycerol (OPO)) in human milk fat substitute (HMFS) on bi...

(This article belongs to the Section Pediatric Nutrition)
  • Article
  • Open Access
14 Citations
4,996 Views
12 Pages

Infant Formula with 50% or More of Palmitic Acid Bound to the sn-2 Position of Triacylglycerols Eliminate the Association between Formula-Feeding and the Increase of Fecal Palmitic Acid Levels in Newborns: An Exploratory Study

  • Hiromichi Shoji,
  • Hiroko Arai,
  • Satsuki Kakiuchi,
  • Atsushi Ito and ,
  • Keigo Sato,
  • Shinji Jinno,
  • Naoto Takahashi,
  • Kenichi Masumoto,
  • Hitoshi Yoda and
  • Toshiaki Shimizu
  • + 5 authors+ 0 author

21 May 2024

The binding ratio of palmitic acid (PA) at the sn-2 position of triacylglycerols in infant formulas is lower than that in breast milk, resulting in higher levels of fecal PA. Even if the ratio is increased to 40–50%, fecal PA levels in formula-...

(This article belongs to the Section Pediatric Nutrition)
  • Article
  • Open Access
29 Citations
6,935 Views
12 Pages

Quantification of 1,3-olein-2-palmitin (OPO) and Palmitic Acid in sn-2 Position of Triacylglycerols in Human Milk by Liquid Chromatography Coupled with Mass Spectrometry

  • Francesca Giuffrida,
  • Cynthia Marmet,
  • Isabelle Tavazzi,
  • Patric Fontannaz and ,
  • Julien Sauser,
  • Le Ye Lee and
  • Frédéric Destaillats
  • + 2 authors+ 0 author

21 December 2018

This study describes the identification and quantification of fatty acids in the sn-2 position of triacylglycerols (TAG) and of the most abundant TAG regioisomers in human milk by liquid chromatography coupled with high-resolution mass spectrometry (...

(This article belongs to the Special Issue Biological Sample Analysis by Liquid Chromatography)
  • Article
  • Open Access
7 Citations
4,077 Views
16 Pages

28 December 2022

Total fatty acid and sn-2 fatty acid compositions, and triacylglycerol (TAG) species in 130 sow colostrum, 100 sow milk, and 22 piglet formula samples were analyzed in the present study. Significant differences were found in concentrations of medium...

(This article belongs to the Topic New Insights into the Milk 2.0)
  • Article
  • Open Access
51 Citations
5,930 Views
15 Pages

Biological processes of legumes may change their nutritional value of lipids, but there is no research on the fatty acid profile and their position distribution in fermented beverages obtained from germinated bean seeds. The present study aimed to de...

(This article belongs to the Special Issue Microbial Populations of Fermented Foods)
  • Review
  • Open Access
59 Citations
14,285 Views
11 Pages

Effects of Plant Oil Interesterified Triacylglycerols on Lipemia and Human Health

  • Andreina Alfieri,
  • Esther Imperlini,
  • Ersilia Nigro,
  • Daniela Vitucci and ,
  • Stefania Orrù,
  • Aurora Daniele,
  • Pasqualina Buono and
  • Annamaria Mancini
  • + 3 authors+ 0 author

30 December 2017

The position of the fatty acids (sn-1, sn-2 and sn-3) (stereospecific numbering (sn)) in triacylglycerol (TAG) molecules produces a characteristic stereospecificity that defines the physical properties of the fats and influences their absorption, met...

(This article belongs to the Special Issue The Beneficial Effects of Plant Oil on Human Health)
  • Article
  • Open Access
6 Views
16 Pages

“Unequal Twins”: The Unique Structural Composition of Triacylglycerols in Oleaginous Ochrophytes from the IPPAS Collection

  • Roman Sidorov,
  • Anastasia Krapivina,
  • Giorgi Kazakov,
  • Alexander Starikov and ,
  • David Gabrielyan and
  • Maria Sinetova
  • + 1 author+ 0 author

1 November 2026

Microalgae are widely regarded as promising sustainable sources of edible oils and nutraceuticals. However, the evaluation of their biotechnological potential is often limited to the fatty acid (FA) composition of total lipids (TL), overlooking the r...

(This article belongs to the Special Issue Chemical Ecology Meets Pharmacognosy: Searching Algal (Chemio)diversity)
  • Article
  • Open Access
13 Citations
4,095 Views
7 Pages

Simultaneous Quantification of Mixed-Acid Triacylglycerol Positional Isomers and Enantiomers in Palm Oil and Lard by Chiral High-Performance Liquid Chromatography Coupled with Mass Spectrometry

  • Toshiharu Nagai,
  • Tetsuaki Kinoshita,
  • Erika Kasamatsu,
  • Kazuaki Yoshinaga and ,
  • Hoyo Mizobe,
  • Akihiko Yoshida,
  • Yutaka Itabashi and
  • Naohiro Gotoh
  • + 3 authors+ 0 author

19 August 2020

Palm oil and lard are edible fats which are rich in palmitic (P) and oleic acids (O). In this study, triacylglycerol (TAG) positional isomers (symmetric and asymmetric isomers) and enantiomers (asymmetric isomers) in palm oil and lard were quantified...

(This article belongs to the Special Issue Recent Advances in the Analysis, Distribution and Functions of Enantiomers and Regioisomers of Biomolecules)
  • Article
  • Open Access
14 Citations
5,564 Views
17 Pages

Lipase-Catalyzed Synthesis of Structured Fatty Acids Enriched with Medium and Long-Chain n-3 Fatty Acids via Solvent-Free Transesterification of Skipjack Tuna Eyeball Oil and Commercial Butterfat

  • Khurshid Ahmed Baloch,
  • Umesh Patil,
  • Khamtorn Pudtikajorn,
  • Ebtihal Khojah and ,
  • Mohammad Fikry and
  • Soottawat Benjakul
  • + 1 author+ 0 author

22 January 2024

Human milk lipids generally have the maximum long-chain fatty acids at the sn-2 position of the glycerol backbone. This positioning makes them more digestible than long-chain fatty acids located at the sn-1, 3 positions. These unique fatty acid distr...

(This article belongs to the Section Foods of Marine Origin)
  • Article
  • Open Access
1,198 Views
17 Pages

Comparative Analysis of Signature Lipid Structures in Canine and Feline Milk Compared with Bovine and Caprine Milk

  • Ying Chen,
  • Jinyue Yang,
  • Chengcheng Wang,
  • Yuming Wang and ,
  • Hongwei Zhang,
  • Xiaomei Zhang,
  • Min Wen and
  • Tiantian Zhang
  • + 3 authors+ 0 author

25 February 2026

This study systematically compared the lipidomes of canine, feline, bovine, and caprine milk. Feline milk contained the highest total lipid content (110.83 mg/mL), significantly exceeding that of canine (81.52 mg/mL), caprine (40.27 mg/mL), and bovin...

(This article belongs to the Section Animal Products)
  • Article
  • Open Access
5 Citations
2,958 Views
13 Pages

Evaluation of the Thermal Behavior of Commercial Cold-Pressed Oils Obtained from Apricot and Peach By-Products

  • Magdalena Wirkowska-Wojdyła,
  • Ewa Ostrowska-Ligęza,
  • Agata Górska,
  • Rita Brzezińska and
  • Iga Piasecka

25 November 2024

Fruit kernels are bio-waste in the food industry and can be managed as oil raw materials. The aim of the study was to investigate the stability, oxidation resistance, profile of fatty acids, and their distribution at the triacylglycerol positions of...

(This article belongs to the Special Issue Emerging Analytical Techniques in Food Industry and Agricultural Products)
  • Article
  • Open Access
21 Citations
5,148 Views
21 Pages

30 June 2021

Tripalmitin-(PPP, 81.2%), 1,3-dipalmitoyl-2-oleoylglycerol-(POP, 64.4%), 1,2-dipalmitoyl-3-oleoylglycerol-(PPO, 86.5%), and 1,3-dioleoyl-2-palmitoylglycerol-(OPO, 50.2%)-rich lipids with different regiospecific positions of palmitic acid (P) were syn...

(This article belongs to the Section Natural Products Chemistry)
  • Article
  • Open Access
10 Citations
5,723 Views
23 Pages

After being harvested, cacao beans are usually subjected to very complex processes in order to improve their chemical and physical characteristics, like tastefulness with chocolate characteristic flavors. The traditional process consists of three maj...

(This article belongs to the Special Issue Volatile Compounds in Food Chemistry)
  • Feature Paper
  • Article
  • Open Access
13 Citations
4,034 Views
16 Pages

Production of Human Milk Fat Substitutes by Lipase-Catalyzed Acidolysis: Immobilization, Synthesis, Molecular Docking and Optimization Studies

  • Cleide M. F. Soares,
  • Milson S. Barbosa,
  • Samuel B. Santos,
  • Silvana Mattedi and ,
  • Álvaro S. Lima,
  • Matheus M. Pereira,
  • Carla Tecelão and
  • Suzana Ferreira-Dias
  • + 3 authors+ 0 author

29 April 2023

Human milk fat (HMF) triacylglycerols (TAGs) mainly contain palmitic acid esterified at the sn-2 position while oleic and other unsaturated fatty acids are located at positions sn-1,3. This study aimed at the production of HMF substitutes (HMFS) by l...

(This article belongs to the Special Issue Enzyme Engineering for Improving the Enzymatic Catalysis, Stability and Substrate Specificity and Application)
  • Article
  • Open Access
30 Citations
8,411 Views
12 Pages

2 December 2015

The triacylglycerol (TAG) structure and the regio-stereospecific distribution of fatty acids (FA) of seed oils from most of the Apiaceae family are not well documented. The TAG structure ultimately determines the final physical properties of the oils...

(This article belongs to the Section Natural Products Chemistry)
  • Article
  • Open Access
10 Citations
7,960 Views
16 Pages

Interesterified Palm Olein (IEPalm) and Interesterified Stearic Acid-Rich Fat Blend (IEStear) Have No Adverse Effects on Insulin Resistance: A Randomized Control Trial

  • Yen Teng Ng,
  • Phooi Tee Voon,
  • Tony Kock Wai Ng,
  • Verna Kar Mun Lee and ,
  • Miskandar Mat Sahri,
  • Norhaizan Mohd Esa,
  • Seng Huat Ong and
  • Augustine Soon Hock Ong
  • + 3 authors+ 0 author

17 August 2018

Chemically-interesterified (CIE) fats are trans-fat free and are increasingly being used as an alternative to hydrogenated oils for food manufacturing industries to optimize their products’ characteristics and nutrient compositions. The metabol...

(This article belongs to the Special Issue Diet, Lipid and Lipoprotein Metabolism and Human Health)
  • Article
  • Open Access
9 Citations
3,439 Views
15 Pages

Effects of the Novel LaPLa-Enriched Medium- and Long-Chain Triacylglycerols on Body Weight, Glycolipid Metabolism, and Gut Microbiota Composition in High Fat Diet-Fed C57BL/6J Mice

  • Jinyuan Shi,
  • Qianqian Wang,
  • Chuang Li,
  • Mengyu Yang and ,
  • Muhammad Hussain,
  • Junhui Zhang,
  • Fengqin Feng and
  • Hao Zhong
  • + 3 authors+ 0 author

11 January 2023

The roles of medium- and long-chain triacylglycerols (MLCT) on health benefits under high fat diet (HFD) conditions remain in dispute. This study was conducted to investigate the effects of novel LaPLa-rich MLCT on the glycolipid metabolism and gut m...

(This article belongs to the Special Issue The Processing and Function of Natural Compounds and Nutraceuticals from Foods)