Special Issue "Diet, Lipid and Lipoprotein Metabolism and Human Health"
A special issue of Nutrients (ISSN 2072-6643).
Deadline for manuscript submissions: closed (31 August 2018).
Interests: human nutrition (macronutrients); plasma lipoproteins; cardio-metabolic risk
Interests: personalised nutrition; dietary fatty acids; polyphenols; vascular dysfunction
The strength of evidence for the relationship between diet and cardiovascular disease (CVD) relies heavily on the effects of dietary fat and carbohydrates on serum biomarkers of CVD risk. Serum cholesterol, triglyceride, and critically the concentration and composition of circulating serum lipoproteins that transport these lipids, are prime examples of such serum biomarkers. Serum lipoproteins are causally related to the formation and regression of atherosclerotic lesions in arteries, are highly responsive to changes in diet and food intake, and have major clinical utility in describing the impact of diet on CVD risk. Despite current debate over the role of saturated fat and CVD, the totality of evidence indicates that both serum LDL cholesterol and CVD mortality can be reduced by replacing saturated fatty acids with polyunsaturated fatty acids. On the other hand, a major priority in the dietary management of cardio-metabolic risk arising from insulin resistance and excess visceral and ectopic fat, is not to lower serum LDL cholesterol, but to reduce the atherogencity of lipoprotein remnants, small, dense LDL and dysfunctional HDL. Increasing the intake of dietary long chain n-3 polyunsaturated fatty acids and fibre, at the expense of reducing free sugars, are two ways in which the quality of dietary fat and carbohydrate can be altered to achieve this aim.
This Special Issue welcomes original research and reviews of literature concerning serum lipids, lipoproteins and health under the following topics:
- Human dietary intervention studies that provide evidence for the effects of dietary fatty acids and/or carbohydrates on serum lipids and lipoproteins
- Studies of human genotypes and/or metabolic phenotypes to help explain variation in lipid and lipoprotein responses to dietary macronutrients
- Studies that provide mechanistic insights into the inter-relationship between diet, body composition and serum lipids and lipoproteins and CVD risk
- Effects of dietary patterns and/or specific food groups on serum lipids and lipoproteins
Prof. Bruce A. Griffin
Prof. Julie A. Lovegrove
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Serum lipids
- Serum lipoproteins
- Cardiovascular disease
- Cardio-metabolic risk
- Metabolic syndrome
- Dietary saturated fatty acids
- Dietary polyunsaturated fatty acids
- Free sugars
- Dietary fibre
- Body fat
- Subcutaneous fat
- Visceral fat
- Ectopic fat