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Int. J. Mol. Sci. 2018, 19(1), 104;

Effects of Plant Oil Interesterified Triacylglycerols on Lipemia and Human Health

Dipartimento di Scienze Motorie e del Benessere, Università degli Studi di Napoli “Parthenope”, via Medina 40, 80133 Napoli, Italy
Ceinge-Biotecnologie Avanzate S.c.a r.l., Via G. Salvatore 486, 80145 Napoli, Italy
IRCCS SDN, via E. Gianturco 113, 80142 Napoli, Italy
Dipartimento di Medicina e di Scienze della Salute “Vincenzo Tiberio”, Università degli Studi del Molise, 86100 Campobasso, Italy
Dipartimento di Scienze e Tecnologie Ambientali Biologiche Farmaceutiche, Università della Campania “Luigi Vanvitelli”, Via G. Vivaldi 42, 81100 Caserta, Italy
These authors contributed equally to this work.
Authors to whom correspondence should be addressed.
Received: 31 October 2017 / Revised: 22 December 2017 / Accepted: 26 December 2017 / Published: 30 December 2017
(This article belongs to the Special Issue The Beneficial Effects of Plant Oil on Human Health)
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The position of the fatty acids (sn-1, sn-2 and sn-3) (stereospecific numbering (sn)) in triacylglycerol (TAG) molecules produces a characteristic stereospecificity that defines the physical properties of the fats and influences their absorption, metabolism and uptake into tissues. Fat interesterification is a process that implies a positional distribution of fatty acids (FAs) within the TAG molecules, generating new TAG species, without affecting the FA cis-trans natural balance. The interesterified (IE) fats, frequently used in the food industry comprise fats that are rich in long-chain saturated FAs, such as palmitic acid (16:0) and stearic acid (18:0). Within the interesterified fats, a critical role is played by FA occupying the sn-2 position; in fact, the presence of an unsaturated FA in this specific position influences early metabolic processing and postprandial clearance that in turn could induce atherogenesis and thrombogenesis events. Here, we provide an overview on the role of TAG structures and interesterified palmitic and stearic acid-rich fats on fasting and postprandial lipemia, focusing our attention on their physical properties and their effects on human health. View Full-Text
Keywords: fatty acids (FAs); interesterified fats; human health; lipemia; stereospecificity; TAG structure fatty acids (FAs); interesterified fats; human health; lipemia; stereospecificity; TAG structure

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Alfieri, A.; Imperlini, E.; Nigro, E.; Vitucci, D.; Orrù, S.; Daniele, A.; Buono, P.; Mancini, A. Effects of Plant Oil Interesterified Triacylglycerols on Lipemia and Human Health. Int. J. Mol. Sci. 2018, 19, 104.

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