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  • Review
  • Open Access
50 Citations
7,340 Views
24 Pages

Lipases as Effective Green Biocatalysts for Phytosterol Esters’ Production: A Review

  • Adejanildo da S. Pereira,
  • Aline Habibe de Souza,
  • Jully L. Fraga,
  • Pierre Villeneuve,
  • Alexandre G. Torres and
  • Priscilla F. F. Amaral

13 January 2022

Lipases are versatile enzymes widely used in the pharmaceutical, cosmetic, and food industries. They are green biocatalysts with a high potential for industrial use compared to traditional chemical methods. In recent years, lipases have been used to...

  • Article
  • Open Access
4 Citations
3,569 Views
22 Pages

Phase Behavior and Polymorphism of Saturated and Unsaturated Phytosterol Esters

  • Eva Daels,
  • Imogen Foubert,
  • Zheng Guo,
  • Wim Thielemans and
  • Bart Goderis

4 December 2020

This study investigated how the physicochemical characteristics of phytosterol esters are influenced by the chain length and degree of unsaturation of the fatty acid ester moiety. Saturated and unsaturated phytosterol esters (PEs) were synthesized by...

  • Article
  • Open Access
305 Views
15 Pages

Phytosterol Oleate Ester Replacing Cholesterol to Enhance Lutein Liposome Stability: A Mechanistic Study

  • Zimeng Zhao,
  • Pengtao Xu,
  • Zhenchen Luo,
  • Wei Chen,
  • Duoxia Xu,
  • Yanbo Wang and
  • Shaojia Wang

3 February 2026

Hydrophobic bioactive compounds such as lutein exhibit poor water solubility and are prone to degradation. Liposomal delivery systems can enhance the solubility and physicochemical stability of lutein (LUT). Liposomes are primarily composed of phosph...

  • Article
  • Open Access
5 Citations
2,217 Views
13 Pages

1 February 2024

The conjugation of phytosterols (PSs) with fatty acids results in producing phytosterol esters (PSEs) characterized by enhanced lipophilicity and improved functional properties of major interest in food and nutraceutical applications. The use of immo...

  • Article
  • Open Access
3 Citations
2,414 Views
21 Pages

Consumption of phytosterols is a nutritional strategy employed to reduce cholesterol absorption, but recent research shows that their biological activity might go beyond cholesterol reduction for the treatment of metabolic dysfunction-associated fatt...

  • Review
  • Open Access
9 Citations
4,022 Views
13 Pages

14 April 2022

Phytosterols are functional ingredients with known efficacy and safety. Phytosterols are found as free sterols or as their esters with fatty acids. Although phytosterol esters are soluble in oil and have been used in many commercial foods, it has bee...

  • Article
  • Open Access
4 Citations
2,039 Views
8 Pages

14 November 2022

Concerns have been raised about the safety and tolerability of phytosterol esters due to their vulnerability to oxidation. Herein, oxidation of the unsaturated fatty acid-phytosterol ester, namely β-sitosteryl oleate, was observed in comparison...

  • Feature Paper
  • Review
  • Open Access
4 Citations
2,560 Views
17 Pages

Advancements in the Esterification of Phytosterols Catalyzed by Immobilized Lipase

  • Yuyang Zhang,
  • Yan Yan,
  • Zhiyuan Lin,
  • Fanzhuo Kong,
  • Xing Ni,
  • Xue Zhang,
  • Yani Zhao,
  • Qiongya Lu and
  • Bin Zou

27 February 2025

Phytosterol exhibits cholesterol-lowering, cardiovascular-protecting, anti-inflammatory, and anticancer efficacies but has low bioavailability due to its high melting point and poor solubility. Esterification with fatty acids enhances liposolubility,...

  • Article
  • Open Access
9 Citations
3,115 Views
25 Pages

The aim of this experiment was to investigate the effects of dietary Phytosterol Ester (PSE) supplementation on egg characteristics, eggshell ultrastructure, antioxidant capacity, liver function, hepatic metabolites, and its mechanism of action in Hy...

  • Article
  • Open Access
1 Citations
1,843 Views
15 Pages

Selection of Yarrowia lipolytica Lipases for Efficient Ester Synthesis or Hydrolysis

  • Aline Habibe de Souza,
  • Mylla F. C. de Moura,
  • Rafaelle C. B. Franson,
  • Tamires Carvalho,
  • Marcel G. Martins,
  • Adejanildo da Silva Pereira,
  • Alexandre G. Torres and
  • Priscilla F. F. Amaral

2 December 2024

The species Yarrowia lipolytica is an aerobic yeast that produces different lipase isoforms, including extracellular, intracellular, and membrane-bound ones. The immobilization of lipases, such as those from Y. lipolytica, increases enzyme stability...

  • Article
  • Open Access
37 Citations
5,498 Views
15 Pages

22 January 2019

In this study, Candida rugosa lipase (CRL) was immobilized into modified hollow mesoporous silica (HMSS) materials with different hydrophobicity. Among propyl-(C3), phenyl-(C6), octyl-(C8), and octadecyl-(C18) modified HMSS as well as native HMSS, ta...

  • Article
  • Open Access
724 Views
20 Pages

28 September 2025

Plantsterol esters (PSEs) exert beneficial effects on animal product quality, indicating their potential as a nutritional intervention strategy. This study investigated the effects of dietary PSE supplementation on lactation performance and lipid met...

  • Article
  • Open Access
5 Citations
2,740 Views
16 Pages

β-Sitosterol Oleate Synthesis by Candida rugosa Lipase in a Solvent-Free Mini Reactor System: Free and Immobilized on Chitosan-Alginate Beads

  • Adejanildo da S. Pereira,
  • Jully L. Fraga,
  • Camila P. L. Souza,
  • Alexandre G. Torres and
  • Priscilla F. F. Amaral

21 April 2023

Candida rugosa lipase (CRL) was immobilized by the ionic gelling technique using alginate and chitosan as encapsulating agents. An immobilization yield of 99% and an immobilization efficiency of 51% were obtained. Maximum hydrolytic activity for free...

  • Article
  • Open Access
6 Citations
4,406 Views
13 Pages

9 November 2024

Chocolate, particularly dark chocolate, is recognized for its antioxidant properties attributed to the presence of flavonoids that promote cardiovascular health. Enriching chocolate with phytosterols, naturally occurring plant compounds known to be e...

  • Article
  • Open Access
5 Citations
3,459 Views
17 Pages

Selective and Efficient Synthesis of Pine Sterol Esters Catalyzed by Deep Eutectic Solvent

  • Honggang Shi,
  • Zeping Lu,
  • Huajin Xu,
  • Shushu Wang,
  • Binbin Nian and
  • Yi Hu

19 January 2023

Phytosterol esters have attracted widespread academic and industrial interests due to their advantages in lowering cholesterol, as antioxidants, and in preventing or treating cancer. However, the generation of by-products limits the application of ph...

  • Article
  • Open Access
10 Citations
3,827 Views
15 Pages

Phytochemical Characterization and In Vitro Anti-Inflammatory Evaluation in RAW 264.7 Cells of Jatropha cordata Bark Extracts

  • Yazmín B. Jiménez-Nevárez,
  • Miguel Angel Angulo-Escalante,
  • Julio Montes-Avila,
  • Araceli Guerrero-Alonso,
  • Judith González Christen,
  • Israel Hurtado-Díaz,
  • J. Basilio Heredia,
  • Eber Addí Quintana-Obregón and
  • Laura Alvarez

26 January 2023

The inflammatory process, although beneficial, can produce tissue damage and systemic damage when uncontrolled. Effective therapeutic alternatives with little or no side effects are of great therapeutic interest. This study aimed to determine the phy...

  • Article
  • Open Access
17 Citations
4,611 Views
21 Pages

Quantitative Profiling of Carotenoids, Tocopherols, Phytosterols, and Fatty Acids in the Flower Petals of Ten Marigold (Tagetes spp. L.) Cultivars

  • Ramesh Kumar Saini,
  • Hui-Yeon Ahn,
  • Geon-Woo Park,
  • Ji-Won Shin,
  • Jung-Hoon Lee,
  • Ji-Woo Yu,
  • Min-Ho Song,
  • Young-Soo Keum and
  • Ji-Ho Lee

24 September 2023

Marigold (Tagetes spp.) flower petals are the most vital sources of carotenoids, especially lutein esters, for the production of natural lutein to use for food, feed, and pharmaceutical industries. Several marigold cultivars are cultivated globally;...

  • Article
  • Open Access
1 Citations
628 Views
25 Pages

Changes in Resveratrol Containing Phytosterol Liposomes During Model Heating

  • Joanna Igielska-Kalwat,
  • Magdalena Rudzińska,
  • Anna Grygier,
  • Dominik Kmiecik,
  • Katarzyna Cieślik-Boczula and
  • Jolanta Tomaszewska-Gras

3 December 2025

Background: Phytosterols are bioactive lipids susceptible to oxidation, particularly under thermal stress. Incorporation into liposomes may enhance their stability, while resveratrol—a natural antioxidant—could further limit thermal degra...

  • Article
  • Open Access
109 Citations
7,379 Views
22 Pages

16 November 2019

Phytosterols, found in many commonly consumed foods, exhibit a broad range of physiological activities including anti-inflammatory effects. In this study, the anti-inflammatory effects of ergosterol, β-sitosterol, stigmasterol, campesterol, and...

  • Review
  • Open Access
57 Views
17 Pages

Phytosterol Profiling as a Tool for Edible Oil Authentication: Challenges and Prospects

  • Kaili Cheng,
  • Tong Zhou,
  • Wei Wang,
  • Jiuliang Zhang,
  • Xiaoting Zhou,
  • Bing Hu and
  • Tao Zhang

20 March 2026

The global edible oil market is consistently at risk of economically motivated adulteration, underscoring the necessity of robust analytical methods essential for authentication. Among various phytochemicals, phytosterols have emerged as powerful dia...

  • Feature Paper
  • Article
  • Open Access
11 Citations
3,253 Views
14 Pages

Distigmasterol-Modified Acylglycerols as New Structured Lipids—Synthesis, Identification and Cytotoxicity

  • Magdalena Rudzińska,
  • Aleksandra Grudniewska,
  • Anna Chojnacka,
  • Witold Gładkowski,
  • Gabriela Maciejewska,
  • Anna Olejnik and
  • Katarzyna Kowalska

12 November 2021

Plant sterols, also referred as phytosterols, have been known as bioactive compounds which have cholesterol-lowering properties in human blood. It has been established that a diet rich in plant sterols or their esters alleviates cardiovascular diseas...

  • Article
  • Open Access
1 Citations
2,361 Views
12 Pages

Phytosterol Depletion in Soybean Oil Using a Synthetic Silica Adsorbent

  • Birgit Steiner-Zitzenbacher,
  • Joaquín Velasco,
  • Crispulo Gallegos and
  • Maria-Victoria Ruiz-Méndez

6 October 2024

Phytosterols in vegetable oils have gained attention for their nutritional benefits in foods and food supplements. However, the use of vegetable oils in emulsions for infant formulas and parenteral nutrition has raised some concerns, as phytosterols...

  • Review
  • Open Access
70 Citations
11,703 Views
17 Pages

A Comprehensive Review on Therapeutic Perspectives of Phytosterols in Insulin Resistance: A Mechanistic Approach

  • Monisha Prasad,
  • Selvaraj Jayaraman,
  • Mohamed Ahmed Eladl,
  • Mohamed El-Sherbiny,
  • Mosaab Abdella Ebrahim Abdelrahman,
  • Vishnu Priya Veeraraghavan,
  • Srinivasan Vengadassalapathy,
  • Vidhya Rekha Umapathy,
  • Shazia Fathima Jaffer Hussain and
  • Ponnulakshmi Rajagopal
  • + 4 authors

28 February 2022

Natural products in the form of functional foods have become increasingly popular due to their protective effects against life-threatening diseases, low risk of adverse effects, affordability, and accessibility. Plant components such as phytosterol,...

  • Review
  • Open Access
6 Citations
2,495 Views
12 Pages

Atomic Force Microscopy of Phytosterol Based Edible Oleogels

  • Andrew B. Matheson,
  • Vasileios Koutsos,
  • Stephen R. Euston and
  • Paul S. Clegg

15 September 2023

This work reviews the use of atomic force microscopy (AFM) as a tool to investigate oleogels of edible triglyceride oils. Specific attention is given to those oleogels based on phytosterols and their esters, a class of material the authors have studi...

  • Review
  • Open Access
9 Citations
7,604 Views
18 Pages

Bioactive Sugarcane Lipids in a Circular Economy Context

  • Francisca S. Teixeira,
  • Susana S. M. P. Vidigal,
  • Lígia L. Pimentel,
  • Paula T. Costa,
  • Manuela E. Pintado and
  • Luís M. Rodríguez-Alcalá

19 May 2021

Most of the global sugar and ethanol supply trade comes from the harvesting of Saccharum officinarum (i.e., sugarcane). Its industrial processing results in numerous by-products and waste streams, such as tops, straw, filter cake, molasses and bagass...

  • Article
  • Open Access
1,689 Views
18 Pages

Chemical and Biological Investigation of Ceiba chodatii Hassl. Flowers

  • Engy Saadalah Ibrahem,
  • John Refaat Fahim,
  • Mamdouh Nabil Samy,
  • Ahmed G. Darwish,
  • Samar Yehia Desoukey,
  • Mohamed Salah Kamel and
  • Samir A. Ross

12 February 2025

Ceiba (syn. Chorisia) trees have attracted multifaceted attention not only due to their ornamental and economic value but also for their remarkable metabolic diversity and therapeutic properties. In view of that, this work explores the chemical compo...

  • Article
  • Open Access
9 Citations
3,155 Views
13 Pages

Cholesterol Metabolic Profiling of HDL in Women with Late-Onset Preeclampsia

  • Tamara Antonić,
  • Daniela Ardalić,
  • Sandra Vladimirov,
  • Aleksandra Zeljković,
  • Jelena Vekić,
  • Marija Mitrović,
  • Jasmina Ivanišević,
  • Tamara Gojković,
  • Jelena Munjas and
  • Aleksandra Stefanović
  • + 2 authors

A specific feature of dyslipidemia in pregnancy is increased high-density lipoprotein (HDL) cholesterol concentration, which is probably associated with maternal endothelium protection. However, preeclampsia is most often associated with low HDL chol...

  • Article
  • Open Access
1 Citations
2,413 Views
16 Pages

A GC-MS Metabolic Study on Lipophilic Compounds in the Leaves of Common Wheat Triticum aestivum L.

  • Asya R. Vasilieva,
  • Nikolay M. Slynko,
  • Nikolay P. Goncharov,
  • Ljudmila E. Tatarova,
  • Leonid V. Kuibida and
  • Sergey E. Peltek

1 August 2024

Common wheat (Triticum aestivum L.) is one of the most valuable cereal crops worldwide. This study examined leaf extracts of 30 accessions of T. aestivum and its subspecies using 48 h maceration with methanol by GC-MS and GCxGC-MS. The plants were gr...

  • Article
  • Open Access
16 Citations
4,126 Views
16 Pages

Lipid Profiles in Preliminary Germinated Brown Rice Beverages Compared to Non-Germinated Brown and White Rice Beverages

  • John C. Beaulieu,
  • Robert A. Moreau,
  • Michael J. Powell and
  • Javier M. Obando-Ulloa

14 January 2022

Brown rice is nutritionally superior to white rice, yet oil rancidity can be problematic during processing and storage regarding sensory attributes. Germinating brown rice is known to generally increase some health-promoting compounds. In response to...

  • Article
  • Open Access
3 Citations
2,915 Views
19 Pages

The Anti-Acne Potential and Chemical Composition of Knautia drymeia Heuff. and Knautia macedonica Griseb Extracts

  • Małgorzata Chrząszcz,
  • Małgorzata Miazga-Karska,
  • Katarzyna Klimek,
  • Michał P. Dybowski,
  • Rafał Typek,
  • Dorota Tchórzewska and
  • Katarzyna Dos Santos Szewczyk

The treatment of acne and other seborrheic diseases has arisen as a significant clinical challenge due to the increasing appearance of multi-drug resistant pathogens and a high frequency of recurrent lesions. Taking into consideration the fact that s...

  • Article
  • Open Access
8 Citations
2,656 Views
25 Pages

Nitrated Fatty-Acids Distribution in Storage Biomolecules during Arabidopsis thaliana Development

  • Lorena Aranda-Caño,
  • Raquel Valderrama,
  • Mounira Chaki,
  • Juan C. Begara-Morales,
  • Manuel Melguizo and
  • Juan B. Barroso

21 September 2022

The non-enzymatic interaction of polyunsaturated fatty acids with nitric oxide (NO) and derived species results in the formation of nitrated fatty acids (NO2-FAs). These signaling molecules can release NO, reversibly esterify with complex lipids, and...

  • Article
  • Open Access
41 Citations
7,848 Views
16 Pages

5 May 2020

The outer-most layer of plant surface, the cuticle, consists of epi- and intra-cuticular wax. It protects the plant from dehydration, extreme temperatures and UV radiation, as well as attacks from pests such as molds and bacteria. Berry cuticular wax...

  • Article
  • Open Access
35 Citations
5,128 Views
22 Pages

Chemical Profiling, Formulation Development, In Vitro Evaluation and Molecular Docking of Piper nigrum Seeds Extract Loaded Emulgel for Anti-Aging

  • Muhammad Yousuf,
  • Haji Muhammad Shoaib Khan,
  • Fatima Rasool,
  • Kashif ur Rehman Khan,
  • Faisal Usman,
  • Bilal Ahmad Ghalloo,
  • Muhammad Umair,
  • Ahmad O. Babalghith,
  • Muhammad Kamran and
  • Carlos Adam Conte-Junior
  • + 4 authors

14 September 2022

Emulgel is a new innovatory technique for drug development permitting controlled release of active ingredients for topical administration. We report a stable emulgel of 4% Piper nigrum extract (PNE) prepared using 80% ethanol. The PNE-loaded formulat...

  • Article
  • Open Access
13 Citations
5,974 Views
27 Pages

The Anti-Acne Potential and Chemical Composition of Two Cultivated Cotoneaster Species

  • Barbara Krzemińska,
  • Michał P. Dybowski,
  • Katarzyna Klimek,
  • Rafał Typek,
  • Małgorzata Miazga-Karska and
  • Katarzyna Dos Santos Szewczyk

21 January 2022

In light of current knowledge on the role of reactive oxygen species and other oxidants in skin diseases, it is clear that oxidative stress facilitates inflammation and is an important factor involved in skin diseases, i.e., acne. Taking into conside...

  • Review
  • Open Access
8 Citations
6,866 Views
18 Pages

Biochemical, Biological, and Clinical Properties of γ-Oryzanol

  • Helena Juricic,
  • Massimiliano Cuccioloni,
  • Laura Bonfili,
  • Mauro Angeletti,
  • Daniela Uberti,
  • Anna Maria Eleuteri,
  • Giulia Abate and
  • Valentina Cecarini

9 September 2025

γ-Oryzanol is a complex mixture of ferulic acid esters of phytosterols and triterpene alcohols predominantly found in rice bran. It exhibits a wide range of biological activities, including antioxidant, anti-inflammatory, and lipid-lowering eff...

  • Feature Paper
  • Review
  • Open Access
14 Citations
4,214 Views
21 Pages

15 December 2022

The genus Lycium belongs to the Solanaceae family and comprises more than 90 species distributed by diverse continents. Lycium barbarum is by far the most studied and has been advertised as a “superfood” with healthy properties. In contra...

  • Article
  • Open Access
10 Citations
2,727 Views
17 Pages

Dietary ω3 Fatty Acids and Phytosterols in the Modulation of the HDL Lipidome: A Longitudinal Crossover Clinical Study

  • Teresa Padro,
  • Anallely López-Yerena,
  • Antonio Pérez,
  • Gemma Vilahur and
  • Lina Badimon

18 August 2023

High-density lipoproteins (HDLs) are complex particles composed of a wide range of lipids, proteins, hormones and vitamins that confer to the HDL particles multiple cardiovascular protective properties, mainly against the development of atheroscleros...

  • Article
  • Open Access
18 Citations
5,322 Views
16 Pages

Lobularia maritima (L.) Desv. Aerial Parts Methanolic Extract: In Vitro Screening of Biological Activity

  • Mariangela Marrelli,
  • Maria Pia Argentieri,
  • Pinarosa Avato and
  • Filomena Conforti

10 January 2020

Lobularia maritima (L.) Desv. is a perennial herb growing wild in the Mediterranean basin. The aim of this work was to assess the fatty acid, terpene, phytosterol, and phenolic composition of the methanolic extract and its sub-fractions using Gas Chr...

  • Article
  • Open Access
1 Citations
2,803 Views
13 Pages

Antimicrobial, Cytotoxic, and Anti-Inflammatory Activities of Tigridia vanhouttei Extracts

  • Jorge L. Mejía-Méndez,
  • Ana C. Lorenzo-Leal,
  • Horacio Bach,
  • Edgar R. López-Mena,
  • Diego E. Navarro-López,
  • Luis R. Hernández,
  • Zaida N. Juárez and
  • Eugenio Sánchez-Arreola

31 August 2023

In this work, bulb extracts of Tigridia vanhouttei were obtained by maceration with solvents of increasing polarity. The extracts were evaluated against a panel of pathogenic bacterial and fungal strains using the minimal inhibitory concentration (MI...

  • Article
  • Open Access
13 Citations
3,645 Views
19 Pages

6 October 2023

Antioxidant and anti-inflammatory mechanisms counteract the pathogenesis of chronic diseases, such as diabetes, aging, and cancer. Therefore, enhancing antioxidant and anti-inflammatory functions may help manage these pathological conditions. This st...

  • Article
  • Open Access
2 Citations
1,658 Views
22 Pages

Modern Comprehensive Metabolomic Profiling of Pollen Using Various Analytical Techniques

  • Petra Krejčí,
  • Zbyněk Žingor,
  • Jana Balarynová,
  • Andrea Čevelová,
  • Matěj Tesárek,
  • Petr Smýkal and
  • Petr Bednář

Pollen is a cornerstone of life for plants. Its durability, adaptability, and complex design are the key factors to successful plant reproduction, genetic diversity, and the maintenance of ecosystems. A detailed study of its chemical composition is i...

  • Article
  • Open Access
39 Citations
8,881 Views
11 Pages

γ-Oryzanol Enhances Adipocyte Differentiation and Glucose Uptake

  • Chang Hwa Jung,
  • Da-Hye Lee,
  • Jiyun Ahn,
  • Hyunjung Lee,
  • Won Hee Choi,
  • Young Jin Jang and
  • Tae-Youl Ha

15 June 2015

Recent studies show that brown rice improves glucose intolerance and potentially the risk of diabetes, although the underlying molecular mechanisms remain unclear. One of the phytochemicals found in high concentration in brown rice is γ-oryzanol (Or...

  • Article
  • Open Access
407 Views
18 Pages

15 January 2026

Rice bran oil (RBO) is increasingly valued for its bioactive constituents and associated health benefits. This study presents a comprehensive comparative analysis of RBOs derived from purple (PRBO), red (RRBO), and white (WRBO) rice bran, focusing on...

  • Article
  • Open Access
22 Citations
7,284 Views
13 Pages

5 September 2019

Elevated blood concentration of low-density lipoprotein cholesterol (LDLc) is a primary risk factor for developing cardiovascular disease. Lifestyle interventions including an increase in dietary phytosterols as well as medications have proven effect...

  • Article
  • Open Access
18 Citations
4,022 Views
16 Pages

Investigation of Potential In Vitro Anticancer and Antimicrobial Activities of Balanites aegyptiaca (L.) Delile Fruit Extract and Its Phytochemical Components

  • Omer H. M. Ibrahim,
  • Adel D. Al-Qurashi,
  • Khalid A. Asiry,
  • Magdi A. A. Mousa,
  • Nabil A. Alhakamy and
  • Kamal A. M. Abo-Elyousr

5 October 2022

The therapeutic importance of Balanites aegyptiaca in folk medicine for the treatment of several common human diseases has led researchers to conduct phytochemical and pharmacological studies on extracts from various parts of the plant. In the curren...

  • Article
  • Open Access
4 Citations
5,355 Views
23 Pages

A Bidens pilosa L. Non-Polar Extract Modulates the Polarization of Human Macrophages and Dendritic Cells into an Anti-Inflammatory Phenotype

  • Xandy Melissa Rodríguez Mesa,
  • Leonardo Andres Contreras Bolaños,
  • Geison Modesti Costa,
  • Antonio Luis Mejia and
  • Sandra Paola Santander González

14 October 2023

Different communities around the world traditionally use Bidens pilosa L. for medicinal purposes, mainly for its anti-inflammatory, antinociceptive, and antioxidant properties; it is used as an ingredient in teas or herbal medicines for the treatment...

  • Feature Paper
  • Article
  • Open Access
28 Citations
9,238 Views
11 Pages

NMR-Based Chemical Profiling, Isolation and Evaluation of the Cytotoxic Potential of the Diterpenoid Siderol from Cultivated Sideritis euboea Heldr.

  • Ekaterina-Michaela Tomou,
  • Maria V. Chatziathanasiadou,
  • Paschalina Chatzopoulou,
  • Andreas G. Tzakos and
  • Helen Skaltsa

Diterpenes are characteristic compounds from the genus Sideritis L., possessing an array of biological activities. Siderol is the main constituent of the ent-kaurene diterpenes in Sideritis species. In order to isolate the specific compound and evalu...

  • Review
  • Open Access
28 Citations
16,569 Views
27 Pages

4 December 2008

Different plant products have been subjected to detailed investigations due to their increasing importance for improving human health. Plants are sources of many groups of natural products, of which large number of new compounds has already displayed...

  • Article
  • Open Access
6 Citations
3,353 Views
11 Pages

14 December 2022

The study was performed to assess and rationalize the traditional utilization of the fruit part of Grewia tenax (G. tenax). The phytoconstituents present in the methanolic extract were analyzed using Gas-Chromatography-Mass Spectroscopy (GC-MS), whil...