Skip to Content

36 Results Found

  • Article
  • Open Access
18 Citations
2,943 Views
15 Pages

Local Structure Awareness-Based Retinal Microaneurysm Detection with Multi-Feature Combination

  • Jiakun Deng,
  • Puying Tang,
  • Xuegong Zhao,
  • Tian Pu,
  • Chao Qu and
  • Zhenming Peng

Retinal microaneurysm (MA) is the initial symptom of diabetic retinopathy (DR). The automatic detection of MA is helpful to assist doctors in diagnosis and treatment. Previous algorithms focused on the features of the target itself; however, the loca...

  • Article
  • Open Access
18 Citations
8,076 Views
14 Pages

Deep Learning Approach for Automatic Microaneurysms Detection

  • Muhammad Mateen,
  • Tauqeer Safdar Malik,
  • Shaukat Hayat,
  • Musab Hameed,
  • Song Sun and
  • Junhao Wen

11 January 2022

In diabetic retinopathy (DR), the early signs that may lead the eyesight towards complete vision loss are considered as microaneurysms (MAs). The shape of these MAs is almost circular, and they have a darkish color and are tiny in size, which means t...

  • Article
  • Open Access
539 Views
19 Pages

An Improved Microaneurysms Detection for Diabetic Retinopathy Screening Using YOLO

  • Sarni Suhaila Rahim,
  • Ankur Deo,
  • Rafia Mumtaz and
  • Vasile Palade

Background/Objectives: Diabetic retinopathy (DR) is a chronic, progressive complication of diabetes mellitus and remains one of the leading causes of vision impairment worldwide, particularly when early pathological changes go undetected or untreated...

  • Article
  • Open Access
22 Citations
3,593 Views
16 Pages

An Improved Microaneurysm Detection Model Based on SwinIR and YOLOv8

  • Bowei Zhang,
  • Jing Li,
  • Yun Bai,
  • Qing Jiang,
  • Biao Yan and
  • Zhenhua Wang

Diabetic retinopathy (DR) is a microvascular complication of diabetes. Microaneurysms (MAs) are often observed in the retinal vessels of diabetic patients and represent one of the earliest signs of DR. Accurate and efficient detection of MAs is cruci...

  • Article
  • Open Access
1,832 Views
16 Pages

10 November 2021

The early diagnosis of retinopathy is crucial to the prevention and treatment of diabetic retinopathy. The low proportion of positive cases in the asymmetric microaneurysm detection problem causes preprocessing to treat microaneurysms as noise to be...

  • Article
  • Open Access
27 Citations
3,440 Views
10 Pages

20 February 2022

Diabetic retinopathy (DR) is one of the most important microvascular complications associated with diabetes mellitus. The early signs of DR are microaneurysms, which can lead to complete vision loss. The detection of DR at an early stage can help to...

  • Article
  • Open Access
29 Citations
4,462 Views
19 Pages

Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism

  • Lizong Zhang,
  • Shuxin Feng,
  • Guiduo Duan,
  • Ying Li and
  • Guisong Liu

17 October 2019

Microaneurysms (MAs) are the earliest detectable diabetic retinopathy (DR) lesions. Thus, the ability to automatically detect MAs is critical for the early diagnosis of DR. However, achieving the accurate and reliable detection of MAs remains a signi...

  • Article
  • Open Access
11 Citations
5,491 Views
14 Pages

Automatic Detection of Microaneurysms in Fundus Images Using an Ensemble-Based Segmentation Method

  • Vidas Raudonis,
  • Arturas Kairys,
  • Rasa Verkauskiene,
  • Jelizaveta Sokolovska,
  • Goran Petrovski,
  • Vilma Jurate Balciuniene and
  • Vallo Volke

24 March 2023

In this study, a novel method for automatic microaneurysm detection in color fundus images is presented. The proposed method is based on three main steps: (1) image breakdown to smaller image patches, (2) inference to segmentation models, and (3) rec...

  • Article
  • Open Access
4 Citations
3,610 Views
19 Pages

Algorithmic Analysis of Vesselness and Blobness for Detecting Retinopathies Based on Fractional Gaussian Filters

  • Maria de Jesus Estudillo-Ayala,
  • Hugo Aguirre-Ramos,
  • Juan Gabriel Avina-Cervantes,
  • Jorge Mario Cruz-Duarte,
  • Ivan Cruz-Aceves and
  • Jose Ruiz-Pinales

All around the world, partial or total blindness has become a direct consequence of diabetes and hypertension. Visual disorders related to these diseases require automatic and specialized methods to detect early malformations, artifacts, or irregular...

  • Article
  • Open Access
5 Citations
2,945 Views
11 Pages

Correlation between Ultra-Wide-Field Retinal Imaging Findings and Vascular Supra-Aortic Changes in Takayasu Arteritis

  • Barthelemy Poignet,
  • Philippe Bonnin,
  • Julien Gaudric,
  • Ismael Chehaibou,
  • Mathieu Vautier,
  • Ramin Tadayoni,
  • Alain Gaudric,
  • Michel Paques,
  • Bahram Bodaghi and
  • Sophie Bonnin
  • + 1 author

24 October 2021

(1) Background: Takayasu arteritis (TA) is a chronic inflammatory large-vessel vasculitis. Ultra-wide-field imaging allows describing the retinal lesions in these patients and correlating them with vascular supra-aortic stenosis. (2) Methods: In tota...

  • Article
  • Open Access
3 Citations
2,484 Views
10 Pages

Allergy Test Dosage of Fluorescein Detects Diabetic Retinopathy Changes in Fundus Fluorescein Angiography

  • Jian-Feng Yang,
  • Yun Wang,
  • Lingling Zhou,
  • Shaoying Tan,
  • Zhanchi Hu,
  • Tsz Kin Ng and
  • Ling-Ping Cen

23 November 2023

Background: The aims of this study were to evaluate the feasibility of allergy test dosage of fluorescein sodium (1%) for Diabetic Retinopathy (DR) detection in Fundus Fluorescein Angiography (FFA) examination as compared to the regular dosage (20%)....

  • Review
  • Open Access
23 Citations
7,001 Views
21 Pages

A Survey on Diabetic Retinopathy Lesion Detection and Segmentation

  • Anila Sebastian,
  • Omar Elharrouss,
  • Somaya Al-Maadeed and
  • Noor Almaadeed

19 April 2023

Diabetes is a global problem which impacts people of all ages. Diabetic retinopathy (DR) is a main ailment of the eyes resulting from diabetes which can result in loss of eyesight if not detected and treated on time. The current process of detecting...

  • Article
  • Open Access
8 Citations
2,588 Views
19 Pages

LezioSeg: Multi-Scale Attention Affine-Based CNN for Segmenting Diabetic Retinopathy Lesions in Images

  • Mohammed Yousef Salem Ali,
  • Mohammed Jabreel,
  • Aida Valls,
  • Marc Baget and
  • Mohamed Abdel-Nasser

8 December 2023

Diagnosing some eye pathologies, such as diabetic retinopathy (DR), depends on accurately detecting retinal eye lesions. Automatic lesion-segmentation methods based on deep learning involve heavy-weight models and have yet to produce the desired qual...

  • Article
  • Open Access
126 Citations
7,815 Views
17 Pages

Diabetic Retinopathy Detection from Fundus Images of the Eye Using Hybrid Deep Learning Features

  • Muhammad Mohsin Butt,
  • D. N. F. Awang Iskandar,
  • Sherif E. Abdelhamid,
  • Ghazanfar Latif and
  • Runna Alghazo

Diabetic Retinopathy (DR) is a medical condition present in patients suffering from long-term diabetes. If a diagnosis is not carried out at an early stage, it can lead to vision impairment. High blood sugar in diabetic patients is the main source of...

  • Article
  • Open Access
16 Citations
4,549 Views
17 Pages

Effective Fundus Image Decomposition for the Detection of Red Lesions and Hard Exudates to Aid in the Diagnosis of Diabetic Retinopathy

  • Roberto Romero-Oraá,
  • María García,
  • Javier Oraá-Pérez,
  • María I. López-Gálvez and
  • Roberto Hornero

16 November 2020

Diabetic retinopathy (DR) is characterized by the presence of red lesions (RLs), such as microaneurysms and hemorrhages, and bright lesions, such as exudates (EXs). Early DR diagnosis is paramount to prevent serious sight damage. Computer-assisted di...

  • Article
  • Open Access
20 Citations
5,112 Views
25 Pages

23 August 2024

Computer vision is a powerful tool in medical image analysis, supporting the early detection and classification of eye diseases. Diabetic retinopathy (DR), a severe eye disease secondary to diabetes, accompanies several early signs of eye-threatening...

  • Article
  • Open Access
98 Citations
7,174 Views
16 Pages

A Novel Approach for Diabetic Retinopathy Screening Using Asymmetric Deep Learning Features

  • Pradeep Kumar Jena,
  • Bonomali Khuntia,
  • Charulata Palai,
  • Manjushree Nayak,
  • Tapas Kumar Mishra and
  • Sachi Nandan Mohanty

Automatic screening of diabetic retinopathy (DR) is a well-identified area of research in the domain of computer vision. It is challenging due to structural complexity and a marginal contrast difference between the retinal vessels and the background...

  • Review
  • Open Access
97 Citations
11,097 Views
28 Pages

Optical Coherence Tomography Angiography in Diabetes and Diabetic Retinopathy

  • Jacqueline Chua,
  • Ralene Sim,
  • Bingyao Tan,
  • Damon Wong,
  • Xinwen Yao,
  • Xinyu Liu,
  • Daniel S. W. Ting,
  • Doreen Schmidl,
  • Marcus Ang and
  • Leopold Schmetterer
  • + 1 author

Diabetic retinopathy (DR) is a common complication of diabetes mellitus that disrupts the retinal microvasculature and is a leading cause of vision loss globally. Recently, optical coherence tomography angiography (OCTA) has been developed to image t...

  • Article
  • Open Access
15 Citations
6,026 Views
25 Pages

Entropy Rate Superpixel Classification for Automatic Red Lesion Detection in Fundus Images

  • Roberto Romero-Oraá,
  • Jorge Jiménez-García,
  • María García,
  • María I. López-Gálvez,
  • Javier Oraá-Pérez and
  • Roberto Hornero

19 April 2019

Diabetic retinopathy (DR) is the main cause of blindness in the working-age population in developed countries. Digital color fundus images can be analyzed to detect lesions for large-scale screening. Thereby, automated systems can be helpful in the d...

  • Article
  • Open Access
67 Citations
9,372 Views
37 Pages

26 August 2022

Diabetic Retinopathy is one of the main causes of vision loss, and in its initial stages, it presents with fundus lesions, such as microaneurysms, hard exudates, hemorrhages, and soft exudates. Computational models capable of detecting these lesions...

  • Review
  • Open Access
41 Citations
21,268 Views
41 Pages

Diabetic retinopathy occurs due to long-term diabetes with changing blood glucose levels and has become the most common cause of vision loss worldwide. It has become a severe problem among the working-age group that needs to be solved early to avoid...

  • Article
  • Open Access
969 Views
19 Pages

A Mask R-CNN-Based Approach for Brain Aneurysm Detection and Segmentation from TOF-MRA Data

  • Emre Aykaç,
  • Gürol Göksungur,
  • Güneş Seda Albayrak and
  • Mehmet Emin Yüksel

30 November 2025

Background: Accurate detection of intracranial aneurysms, especially those smaller than 3 mm, remains a critical challenge in neurovascular imaging due to their subtle morphology and low contrast in Time-of-Flight Magnetic Resonance Angiography (TOF-...

  • Article
  • Open Access
172 Citations
15,062 Views
19 Pages

12 July 2022

Artificial intelligence is widely applied to automate Diabetic retinopathy diagnosis. Diabetes-related retinal vascular disease is one of the world’s most common leading causes of blindness and vision impairment. Therefore, automated DR detecti...

  • Article
  • Open Access
4 Citations
3,348 Views
13 Pages

Direct Photocoagulation for Treating Microaneurysms with Hyperreflective Ring in Eyes with Refractory Macular Edema Associated with Branch Retinal Vein Occlusion

  • Hirofumi Sasajima,
  • Masahiro Zako,
  • Yoshiki Ueta,
  • Hideo Tate,
  • Chisato Otaki,
  • Kenta Murotani,
  • Takafumi Suzuki,
  • Hidetoshi Ishida,
  • Yoshihiro Hashimoto and
  • Naoko Tachi

3 February 2022

Microaneurysms (MAs) with hyperreflective rings are sometimes detected in eyes with refractory macular edema (ME) associated with branch retinal vein occlusion (BRVO) for more than 12 months after onset when examined using optical coherence tomograph...

  • Article
  • Open Access
8 Citations
2,303 Views
13 Pages

Cellular-Level Analysis of Retinal Blood Vessel Walls Based on Phase Gradient Images

  • Mircea Mujat,
  • Konstantina Sampani,
  • Ankit H. Patel,
  • Jennifer K. Sun and
  • Nicusor Iftimia

8 November 2023

Diseases such as diabetes affect the retinal vasculature and the health of the neural retina, leading to vision problems. We describe here an imaging method and analysis procedure that enables characterization of the retinal vessel walls with cellula...

  • Article
  • Open Access
9 Citations
2,745 Views
15 Pages

Phenotypic Differences in a PRPH2 Mutation in Members of the Same Family Assessed with OCT and OCTA

  • Henar Albertos-Arranz,
  • Xavier Sánchez-Sáez,
  • Natalia Martínez-Gil,
  • Isabel Pinilla,
  • Rosa M. Coco-Martin,
  • Jesús Delgado and
  • Nicolás Cuenca

Choroidal dystrophies comprise a group of chorioretinal degenerations. However, the different findings observed among these patients make it difficult to establish a correct clinical diagnosis. The objective of this study was to characterize new clin...

  • Review
  • Open Access
19 Citations
7,095 Views
11 Pages

22 February 2023

Background and Objectives: This study aims to elucidate the role of microaneurysms (MAs) in the pathogenesis and treatment of diabetic retinopathy (DR) and diabetic macular edema (DME), the major causes of acquired visual impairment. Materials and Me...

  • Data Descriptor
  • Open Access
663 Views
11 Pages

1 February 2026

The Indian Diabetic Retinopathy Image Dataset (IDRiD) has been widely adopted for DR lesion segmentation research. However, it contains annotation gaps for proliferative DR lesions and labeling errors that limit its utility for comprehensive automate...

  • Systematic Review
  • Open Access
35 Citations
5,206 Views
25 Pages

Optical Coherence Tomography Angiography in Diabetic Patients: A Systematic Review

  • Ana Boned-Murillo,
  • Henar Albertos-Arranz,
  • María Dolores Diaz-Barreda,
  • Elvira Orduna-Hospital,
  • Ana Sánchez-Cano,
  • Antonio Ferreras,
  • Nicolás Cuenca and
  • Isabel Pinilla

Background: Diabetic retinopathy (DR) is the leading cause of legal blindness in the working population in developed countries. Optical coherence tomography (OCT) angiography (OCTA) has risen as an essential tool in the diagnosis and control of diabe...

  • Article
  • Open Access
2 Citations
2,131 Views
15 Pages

Background: Diabetic retinopathy (DR) is the leading cause of blindness among working-age adults. Early detection is crucial to reducing DR-related vision loss risk but is fraught with challenges. Manual detection is labor-intensive and often misses...

  • Article
  • Open Access
2,004 Views
19 Pages

Background/Objectives: Diabetic macular edema (DME) is the primary cause of vision loss in people with diabetes, and if untreated, it can result in irreversible macular damage. Both fluorescein angiography (FA), the gold standard, and optical coheren...

  • Article
  • Open Access
2 Citations
1,776 Views
19 Pages

Objectives: To evaluate the short- and long-term effects of subthreshold micropulse laser (SMPL) treatment on the microvascular network in diabetic macular edema (DME). Methods: This 12-month prospective study included 67 eyes (67 patients) with mild...

  • Article
  • Open Access
52 Citations
8,613 Views
16 Pages

4 January 2019

Diabetic retinopathy (DR) is a complication of diabetes and is known as visual impairment, and is diagnosed in various ethnicities of the working-age population worldwide. Fundus angiography is a widely applicable modality used by ophthalmologists an...

  • Article
  • Open Access
11 Citations
8,366 Views
11 Pages

Serum Levels of Plasmalogens and Fatty Acid Metabolites Associate with Retinal Microangiopathy in Participants from the Finnish Diabetes Prevention Study

  • Vanessa Derenji de Mello,
  • Tuomas Selander,
  • Jaana Lindström,
  • Jaakko Tuomilehto,
  • Matti Uusitupa and
  • Kai Kaarniranta

14 December 2021

Diabetic retinopathy (DR) is the most common microvascular complication of diabetes, and retinal microaneurysms (MA) are one of the first detected abnormalities associated with DR. We recently showed elevated serum triglyceride levels to be associate...

  • Article
  • Open Access
1,281 Views
17 Pages

Objective: Retinal capillary dropout, characterized by acellular capillaries or “ghost vessels,” is an early pathological sign of diabetic retinopathy (DR) that remains undetectable through standard clinical imaging techniques until visib...

  • Article
  • Open Access
1 Citations
2,299 Views
11 Pages

Microvascular Metrics on Diabetic Retinopathy Severity: Analysis of Diabetic Eye Images from Real-World Data

  • Cristina Cuscó,
  • Pau Esteve-Bricullé,
  • Ana Almazán-Moga,
  • Jimena Fernández-Carneado and
  • Berta Ponsati

Objective: To quantify microvascular lesions in a large real-world data (RWD) set, based on single central retinal fundus images of diabetic eyes from different origins, with the aim of validating its use as a precision tool for classifying diabetic...