You are currently on the new version of our website. Access the old version .

28 Results Found

  • Communication
  • Open Access
23 Citations
5,630 Views
13 Pages

Administration of Dietary Microalgae Ameliorates Intestinal Parameters, Improves Body Weight, and Reduces Thawing Loss of Fillets in Broiler Chickens: A Pilot Study

  • Miroslava Anna Šefcová,
  • Francisco Santacruz,
  • César Marcelo Larrea-Álvarez,
  • Christian Vinueza-Burgos,
  • David Ortega-Paredes,
  • Gabriel Molina-Cuasapaz,
  • Jessica Rodríguez,
  • William Calero-Cáceres,
  • Viera Revajová and
  • Marco Larrea-Álvarez
  • + 1 author

19 December 2021

This pilot investigation aimed at studying the feasibility of using a low dose (0.2%) of dietary microalgae as a means of improving intestinal morphometry, body weight, and selected meat quality parameters in broilers. A total of 72 one-day-old ROSS...

  • Article
  • Open Access
1 Citations
1,298 Views
17 Pages

Modulatory Effects of Tetraselmis chuii Gastrointestinal Digests on Human Colonic Microbiota

  • Marta Majchrzak,
  • Samuel Paterson,
  • Javier Gutiérrez-Corral,
  • Dulcenombre Gómez-Garre,
  • Adriana Ortega-Hernández,
  • Miguel Ángel de la Fuente,
  • Blanca Hernández-Ledesma and
  • Pilar Gómez-Cortés

16 June 2025

Tetraselmis chuii is a microalga commercialized because of its richness in health-beneficial molecules. Previous studies have profusely demonstrated the biological properties of compounds isolated from T. chuii, but data are not yet available on the...

  • Article
  • Open Access
746 Views
24 Pages

Tetraselmis chuii as Source of Bioactive Compounds Against Helicobacter pylori: An Integrated Proteomic and Bioactivity Approach

  • Marta Majchrzak,
  • Samuel Paterson,
  • Pilar Gómez-Cortés,
  • Jose Manuel Silvan,
  • Adolfo J. Martinez-Rodriguez and
  • Blanca Hernández-Ledesma

5 December 2025

Microalgae represent sustainable sources of bioactive compounds with potential health benefits. This study conducted a comprehensive proteomic analysis of Tetraselmis chuii (T. chuii) biomass to identify proteins capable of generating bioactive pepti...

  • Article
  • Open Access
11 Citations
5,099 Views
24 Pages

TetraSOD®, a Unique Marine Microalgae Ingredient, Promotes an Antioxidant and Anti-Inflammatory Status in a Metabolic Syndrome-Induced Model in Rats

  • Katherine Gil-Cardoso,
  • Josep M. Del Bas,
  • Antoni Caimari,
  • Carmen Lama,
  • Sonia Torres,
  • Lalia Mantecón and
  • Carlos Infante

28 September 2022

Increased oxidative stress has been linked to the pathogenic process of obesity and can trigger inflammation, which is often linked with the risk factors that make up metabolic syndrome (MetS), including obesity, insulin resistance, dyslipidaemia and...

  • Article
  • Open Access
18 Citations
4,908 Views
28 Pages

Tetraselmis chuii Edible Microalga as a New Source of Neuroprotective Compounds Obtained Using Fast Biosolvent Extraction

  • Melis Cokdinleyen,
  • Gerardo Alvarez-Rivera,
  • Jose Luis González Tejera,
  • José A. Mendiola,
  • Alberto Valdés,
  • Huseyin Kara,
  • Elena Ibáñez and
  • Alejandro Cifuentes

Tetraselmis chuii is an EFSA-approved novel food and dietary supplement with increasing use in nutraceutical production worldwide. This study investigated the neuroprotective potential of bioactive compounds extracted from T. chuii using green biobas...

  • Article
  • Open Access
11 Citations
4,770 Views
12 Pages

Effects of Tetraselmis chuii Microalgae Supplementation on Ergospirometric, Haematological and Biochemical Parameters in Amateur Soccer Players

  • Víctor Toro,
  • Jesús Siquier-Coll,
  • Ignacio Bartolomé,
  • María C. Robles-Gil,
  • Javier Rodrigo and
  • Marcos Maynar-Mariño

This study aimed to analyse the effects of Tetraselmis chuii (TC) microalgae supplementation during thirty days on ergospirometric, haematological and biochemical parameters in amateur soccer players. Thirty-two amateur soccer players divided into a...

  • Article
  • Open Access
13 Citations
4,054 Views
15 Pages

Effects of Tetraselmis chuii Microalgae Supplementation on Anthropometric, Hormonal and Hematological Parameters in Healthy Young Men: A Double-Blind Study

  • Ángel García,
  • Víctor Toro-Román,
  • Jesús Siquier-Coll,
  • Ignacio Bartolomé,
  • Diego Muñoz and
  • Marcos Maynar-Mariño

The aim of this study was to evaluate the effects of Tetraselmis chuii (TC) microalgae supplementation for sixty days on hematological, anthropometric and hormonal parameters in healthy young men. Forty-six men divided into a placebo group (PG; n = 1...

  • Communication
  • Open Access
4 Citations
3,155 Views
12 Pages

A PMAxxTM qPCR Assay Reveals That Dietary Administration of the Microalgae Tetraselmis chuii Does Not Affect Salmonella Infantis Caecal Content in Early-Treated Broiler Chickens

  • Joselyn Corrales-Martinez,
  • David Ortega-Paredes,
  • Miroslava Anna Šefcová,
  • César Marcelo Larrea-Álvarez,
  • Sofía de Janon,
  • José Medina-Santana,
  • Gabriel Molina-Cuasapaz,
  • Christian Vinueza-Burgos,
  • Viera Revajová and
  • William Calero-Cáceres
  • + 1 author

8 September 2022

Salmonella enterica serovars cause infections in humans. S. enterica subsp. enterica serovar Infantis is considered relevant and is commonly reported in poultry products. Evaluating innovative approaches for resisting colonization in animals could co...

  • Editorial
  • Open Access
3 Citations
4,193 Views
6 Pages

Special Issue: Rheology and Quality Research of Cereal-Based Food

  • Anabela Raymundo,
  • María Dolores Torres and
  • Isabel Sousa

22 October 2020

New trends in the cereal industry deal with a permanent need to develop new food products that are adjusted to consumer demands and, in the near future, the scarcity of food resources. Sustainable food products as health and wellness promoters can be...

  • Article
  • Open Access
52 Citations
5,617 Views
15 Pages

4 May 2020

The objective of this work is to increase the nutritional quality of gluten-free (GF) bread by addition of Tetraselmis chuii microalgal biomass, a sustainable source of protein and bioactive compounds. The impact of different levels of T. chuii (0%&m...

  • Article
  • Open Access
51 Citations
6,963 Views
17 Pages

Protein Enrichment of Wheat Bread with Microalgae: Microchloropsis gaditana, Tetraselmis chui and Chlorella vulgaris

  • Waqas Muhammad Qazi,
  • Simon Ballance,
  • Katerina Kousoulaki,
  • Anne Kjersti Uhlen,
  • Dorinde M. M. Kleinegris,
  • Kari Skjånes and
  • Anne Rieder

10 December 2021

Cell wall disrupted and dried Microchloropsis gaditana (Mg), Tetraselmis chui (Tc) and Chlorella vulgaris (Cv) microalgae biomasses, with or without ethanol pre-treatment, were added to wheat bread at a wheat flour substitution level of 12%, to enric...

  • Article
  • Open Access
735 Views
13 Pages

Effect Produced by a Mixture of Phenol, p-Cresol, and Acetophenone on Four Species of Microalgae: Tolerance, Biodegradation, and Metabolic Alterations

  • Juan Manuel Rastrojo-Velasco,
  • Rosa Leon,
  • Ana Sayago,
  • Angeles Fernandez-Recamales,
  • Javier Vigara and
  • Antonio Leon-Vaz

6 October 2025

Phenol-derived compounds are among the most hazardous organic pollutants for aquatic environments due to their relatively high aqueous solubility. Microalgae harbor metabolic pathways that enable the degradation of phenolic compounds into less toxic...

  • Article
  • Open Access
4 Citations
2,612 Views
14 Pages

Cultivation of Brackish Water Microalgae for Pig Manure Liquid Digestate Recycling

  • Yung-Cheng Chang,
  • Yen-Ju Pan,
  • Tzu-Hsuan Huang,
  • Ting-Hsun Hsiao,
  • Liang-Yu Wei and
  • Te-Hua Hsu

24 November 2023

Sustainability and recycling of agricultural and animal husbandry waste are important. Pig manure contains relatively high concentrations of organic matter, such as nitrate-nitrogen, ammonia nitrogen, and phosphate, and a direct discharge can cause e...

  • Feature Paper
  • Article
  • Open Access
64 Citations
6,761 Views
12 Pages

Improved Extraction Efficiency of Antioxidant Bioactive Compounds from Tetraselmis chuii and Phaedoactylum tricornutum Using Pulsed Electric Fields

  • Marialena Kokkali,
  • Francisco J. Martí-Quijal,
  • Mercedes Taroncher,
  • María-José Ruiz,
  • Katerina Kousoulaki and
  • Francisco J. Barba

27 August 2020

Pulsed electric fields (PEF) is a promising technology that allows the selective extraction of high-added value compounds by electroporation. Thus, PEF provides numerous opportunities for the energy efficient isolation of valuable microalgal bioactiv...

  • Article
  • Open Access
11 Citations
4,231 Views
18 Pages

15 March 2024

At present, the incorporation of microalgae into bread and related cereal products has attracted attention due to their potential for enhancing nutritional profiles and their impact on health. In this study, 4% of Chlorella vulgaris, Phaeodactylum tr...

  • Article
  • Open Access
7 Citations
5,414 Views
15 Pages

The Volatile Composition and the Potential Health Benefits of Different Microalgae Strains

  • Madalena Grácio,
  • Joana Ferreira,
  • Pia Steinrücken,
  • Dorinde M. M. Kleinegris,
  • Isabel Sousa,
  • M. Cristiana Nunes and
  • Anabela Raymundo

10 July 2024

The use of microalgae as a food ingredient has been gaining attention in recent years due to its nutritional benefits. The main goals of this study were to (i) assess the nutritional potential of Chlorella vulgaris, Tetraselmis chuii, Microchloropsis...

  • Review
  • Open Access
5 Citations
3,482 Views
29 Pages

The Potential of Superoxide Dismutase-Rich Tetraselmis chuii as a Promoter of Cellular Health

  • Stuart P. Cocksedge,
  • Lalia Mantecón,
  • Enrique Castaño,
  • Carlos Infante and
  • Stephen J. Bailey

16 February 2025

Tetraselmis chuii (T. chuii) is a green, marine, eukaryotic, microalgae that was authorized in the European Union (EU) as a novel food for human consumption in 2014, and as a food supplement in 2017. This narrative review will provide an overview of...

  • Article
  • Open Access
10 Citations
3,728 Views
22 Pages

Assessment of Small Cellular Particles from Four Different Natural Sources and Liposomes by Interferometric Light Microscopy

  • Anna Romolo,
  • Zala Jan,
  • Apolonija Bedina Zavec,
  • Matic Kisovec,
  • Vesna Arrigler,
  • Vesna Spasovski,
  • Marjetka Podobnik,
  • Aleš Iglič,
  • Gabriella Pocsfalvi and
  • Veronika Kralj-Iglič
  • + 1 author

13 December 2022

Small particles in natural sources are a subject of interest for their potential role in intercellular, inter-organism, and inter-species interactions, but their harvesting and assessment present a challenge due to their small size and transient iden...

  • Article
  • Open Access
25 Citations
5,427 Views
19 Pages

Characterization of Selected Microalgae Species as Potential Sources of Nutrients and Antioxidants

  • Natália Čmiková,
  • Przemysław Łukasz Kowalczewski,
  • Dominik Kmiecik,
  • Aneta Tomczak,
  • Agnieszka Drożdżyńska,
  • Mariusz Ślachciński,
  • Jakub Królak and
  • Miroslava Kačániová

8 July 2024

Microalgae are exceptional organisms from a nutritional perspective, boasting an array of bioactive compounds that have long justified their incorporation into human diets. In this study, we explored the potential of five microalgae species: Nannochl...

  • Article
  • Open Access
1 Citations
1,665 Views
22 Pages

Tetraselmis chuii Supplementation Increases Skeletal Muscle Nuclear Factor Erythroid 2-Related Factor 2 and Antioxidant Enzyme Gene Expression, and Peak Oxygen Uptake in Healthy Adults: A Randomised Crossover Trial

  • Stuart P. Cocksedge,
  • Carlos Infante,
  • Sonia Torres,
  • Carmen Lama,
  • Lalia Mantecón,
  • Manuel Manchado,
  • Jarred P. Acton,
  • Nehal S. Alsharif,
  • Tom Clifford and
  • Stephen J. Bailey
  • + 4 authors

Superoxide dismutase-rich Tetraselmis chuii (T. chuii) is derived from marine microalgae and has been reported to increase gene expression of nuclear factor erythroid 2-related factor 2 (NRF2) and related antioxidant enzymes in myoblast tissue cultur...

  • Article
  • Open Access
8 Citations
4,579 Views
13 Pages

28 April 2018

Due to the possible depletion of fossil fuels in the near future and the necessity of finding new food sources for a growing world population, marine microalgae constitutes a very promising alternative resource, which can also contribute to carbon di...

  • Article
  • Open Access
18 Citations
5,409 Views
10 Pages

First Apocarotenoids Profiling of Four Microalgae Strains

  • Mariosimone Zoccali,
  • Daniele Giuffrida,
  • Fabio Salafia,
  • Carmen Socaciu,
  • Kari Skjånes,
  • Paola Dugo and
  • Luigi Mondello

Both enzymatic or oxidative carotenoids cleavages can often occur in nature and produce a wide range of bioactive apocarotenoids. Considering that no detailed information is available in the literature regarding the occurrence of apocarotenoids in mi...

  • Article
  • Open Access
2 Citations
1,885 Views
21 Pages

Neuroprotective Potential of Tetraselmis chuii Compounds: Insights into Blood–Brain Barrier Permeability and Intestinal Transport

  • Melis Cokdinleyen,
  • Alberto Valdés,
  • Huseyin Kara,
  • Elena Ibáñez and
  • Alejandro Cifuentes

26 April 2025

Background/Objectives: Alzheimer’s disease (AD) is the most common type of dementia, characterized by complex processes such as neuro-inflammation, oxidative damage, synaptic loss, and neuronal death. Carotenoids are among the potential therape...

  • Article
  • Open Access
7 Citations
7,422 Views
23 Pages

24 June 2021

We found the euryhaline microalga, Tetraselmis jejuensis sp. nov., which was adapted to supralittoral tide pools with salinities varying from 0.3–3.1%. Fifteen strains of T. jejuensis were isolated from Daejeong (DJ) and Yongduam (YO), and clonal cul...

  • Article
  • Open Access
29 Citations
4,503 Views
14 Pages

12 February 2021

To develop greener extraction alternatives for microalgae biomass, ultrasound assisted extraction (UAE) and pressurized liquid extraction (PLE) with different biobased solvents were investigated, demonstrating that both techniques are useful alternat...

  • Article
  • Open Access
52 Citations
6,812 Views
23 Pages

Variability in Macro- and Micronutrients of 15 Commercially Available Microalgae Powders

  • Fabian Sandgruber,
  • Annekathrin Gielsdorf,
  • Anja C. Baur,
  • Benjamin Schenz,
  • Sandra Marie Müller,
  • Tanja Schwerdtle,
  • Gabriele I. Stangl,
  • Carola Griehl,
  • Stefan Lorkowski and
  • Christine Dawczynski

27 May 2021

The nutrient composition of 15 commercially available microalgae powders of Arthrospira platensis, Chlorella pyrenoidosa and vulgaris, Dunaliella salina, Haematococcus pluvialis, Tetraselmis chuii, and Aphanizomenon flos-aquae was analyzed. The Dunal...

  • Article
  • Open Access
5 Citations
2,541 Views
14 Pages

13 September 2024

DCOIT (4,5-Dichloro-2-octylisothiazol-3(2H)-one) is a widely used antifouling biocide that emerged after the ban on tributyltin. It has been immobilized in nanostructured silica (SiNC–DCOIT) to reduce its hazard in maritime coatings. This study...

  • Article
  • Open Access
50 Citations
6,860 Views
17 Pages

Improving the Nutritional, Structural, and Sensory Properties of Gluten-Free Bread with Different Species of Microalgae

  • Muhammad Waqas Qazi,
  • Inês Gonçalves de Sousa,
  • Maria Cristiana Nunes and
  • Anabela Raymundo

29 January 2022

Microalgae are an enormous source of nutrients that can be utilized to enrich common food of inherently low nutritional value, such as gluten-free (GF) bread. Addition of the algae species: Tetraselmis chuii (Tc), Chlorella vulgaris (Cv), and Nannoch...