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26 Results Found

  • Article
  • Open Access
31 Citations
8,613 Views
7 Pages

Two New Iridoids from Verbena officinalis L.

  • Jicheng Shu,
  • Guixin Chou and
  • Zhengtao Wang

18 July 2014

Two new iridoids, 3-(5-(methoxycarbonyl)-2-oxo-2H-pyran-3-yl)butanoic acid, named verbeofflin I (1), and 7-hydroxydehydrohastatoside (2), were isolated from the aerial part of Verbena officinalis L, along with three known iridoids, verbenalin (3), 3...

(This article belongs to the Section Natural Products Chemistry)
  • Communication
  • Open Access
8 Citations
3,238 Views
8 Pages

In Vitro Antimelanoma Properties of Verbena officinalis Fractions

  • Rabia Nisar,
  • Sanjay Adhikary,
  • Saeed Ahmad and
  • Mohammad Abrar Alam

26 September 2022

Verbena officinalis is commonly used in traditional medicine to treat many ailments. Extracts of this plant are therapeutic agents for the potential treatment of different diseases, including colorectal and liver cancers, but have not been explored f...

(This article belongs to the Special Issue Sustainable Approaches to Natural Product-Inspired Drug Discovery and Development)
  • Article
  • Open Access
10 Citations
4,373 Views
16 Pages

The Essential Oil Composition in Commercial Samples of Verbena officinalis L. Herb from Different Origins

  • Ain Raal,
  • Getter Dolgošev,
  • Tetiana Ilina,
  • Alla Kovalyova and ,
  • Martin Lepiku,
  • Andriy Grytsyk and
  • Oleh Koshovyi
  • + 2 authors+ 0 author

2 April 2025

The key objective of this study was to determine the yield and chemical composition of eight commercial samples and one collected sample of common vervain (Verbena officinalis L.) herb essential oil (EO) originating from seven different countries, an...

  • Article
  • Open Access
3 Citations
3,789 Views
20 Pages

Verbena officinalis L. Herb Extract, Its Amino Acid Preparations and 3D-Printed Dosage Forms: Phytochemical, Technological and Pharmacological Research

  • Oleh Koshovyi,
  • Getter Dolgošev,
  • Udhan Wimukthi Meegama,
  • Koit Herodes and ,
  • Yurii Hrytsyk,
  • Lyubov Grytsyk,
  • Andriy Grytsyk,
  • Igor Kireyev,
  • Jyrki Heinämäki and
  • Ain Raal
  • + 5 authors+ 0 author

26 August 2025

Vervain (Verbena officinalis L., Verbenaceae family) is a perennial plant which grows widely in Europe. It is rich in iridoids, phenolic acids, phenylpropanoid glycosides, flavonoids and terpenoids. Verbena has traditionally been used in folk medicin...

(This article belongs to the Section Phytochemistry)
  • Article
  • Open Access
18 Citations
5,647 Views
15 Pages

Bioactive Constituents of Verbena officinalis Alleviate Inflammation and Enhance Killing Efficiency of Natural Killer Cells

  • Xiangdong Dai,
  • Xiangda Zhou,
  • Rui Shao,
  • Renping Zhao and ,
  • Archana K. Yanamandra,
  • Zhimei Xing,
  • Mingyu Ding,
  • Junhong Wang,
  • Tao Liu and
  • Yu Wang
  • + 10 authors+ 5 authors

Natural killer (NK) cells play key roles in eliminating pathogen-infected cells. Verbena officinalis (V. officinalis) has been used as a medical plant in traditional and modern medicine for its anti-tumor and anti-inflammatory activities, but its eff...

(This article belongs to the Collection Feature Papers in Bioactives and Nutraceuticals)
  • Article
  • Open Access
514 Views
29 Pages

Electrospun Nanofibers Loaded with Verbena officinalis Extract as Multifunctional Bioactive Wound Dressings

  • Nikoleta Đorđevski,
  • Ana Ćirić,
  • Uroš Gašić,
  • Marija Ivanov and ,
  • Alexia Delnatte,
  • Mikhael Bechelany,
  • Dina Tucović,
  • Jelena Kulaš,
  • Maja Čakić-Milošević and
  • Dejan Stojković
  • + 5 authors+ 0 author

13 August 2026

Background/Objectives: Verbena officinalis has long been used in traditional medicine for treating skin disorders, yet its potential in advanced wound-dressing systems remains insufficiently explored. This study aimed to characterize V. officinalis e...

(This article belongs to the Special Issue Natural Pharmacons: Biologically Active Plant-Based Pharmaceuticals—4th Edition)
  • Article
  • Open Access
15 Citations
5,034 Views
20 Pages

Metabolic Profiling by GC-MS, In Vitro Biological Potential, and In Silico Molecular Docking Studies of Verbena officinalis

  • Rabia Nisar,
  • Saeed Ahmad,
  • Kashif-ur-Rehman Khan,
  • Asmaa E. Sherif and ,
  • Fawaz Alasmari,
  • Afaf F. Almuqati,
  • Chitchamai Ovatlarnporn,
  • Mohsin Abbas Khan,
  • Muhammad Umair and
  • Sameh A. Korma
  • + 10 authors+ 5 authors

8 October 2022

Verbena officinalis L. is a traditionally important medicinal herb that has a rich source of bioactive phytoconstituents with biological benefits. The objective of this study was to assess the metabolic profile and in vitro biological potential of V....

(This article belongs to the Special Issue Natural Products and Their Synthetic Scaffolds for Chronic Diseases: A Ray of Hope)
  • Article
  • Open Access
6 Citations
4,843 Views
23 Pages

Exercise Training and Verbena officinalis L. Affect Pre-Clinical and Histological Parameters

  • Sonia M. Rodrigues Oliveira,
  • Elsa Dias,
  • Ana Paula Girol,
  • Helena Silva and
  • Maria de Lourdes Pereira

15 November 2022

Verbena officinalis L. or vervain is an herbal medicine and dietary supplement used worldwide. It is used for antidepressant and anticonvulsant purposes, as well as to treat inflammatory disorders, skin burns, abrasions, and gastric diseases, among o...

(This article belongs to the Special Issue New Insights in the Research of Bioactive Compounds from Plant Origin with Nutraceutical and Pharmaceutical Potential II)
  • Abstract
  • Open Access
1,763 Views
1 Page

Verbena officinalis or vervain is globally used as an herbal medicine and dietary supplement for anti-depressive and anti-convulsive purposes, as well as to treat inflammatory disorders, skin burns, abrasions and gastric problems. In our exploratory...

(This article belongs to the Proceedings of The 1st International e-Conference on Antioxidants in Health and Disease)
  • Article
  • Open Access
7 Citations
2,180 Views
23 Pages

Investigation of Bioactive Compounds Extracted from Verbena officinalis and Their Biological Effects in the Extraction by Four Butanol/Ethanol Solvent Combinations

  • Dejan Stojković,
  • Nikoleta Đorđevski,
  • Mladen Rajaković,
  • Biljana Filipović and ,
  • Jelena Božunović,
  • Stefani Bolevich,
  • Gokhan Zengin,
  • Sergey Bolevich,
  • Uroš Gašić and
  • Marina Soković
  • + 5 authors+ 0 author

Background/Objectives: Verbena officinalis L. (common vervain) is a medicinal plant traditionally used and investigated in phytotherapy for its neuroprotective, antioxidant, and anti-inflammatory properties. This study aims to investigate the phytoch...

(This article belongs to the Section Natural Products)
  • Article
  • Open Access
1 Citations
565 Views
19 Pages

25 June 2026

Verbena officinalis L., a classic medicinal plant of the Verbenaceae family with wide clinical applications, contains alkaloids and steroids with potent anti-inflammatory and anti-psoriatic activities. However, its whole-plant chemical composition an...

(This article belongs to the Special Issue Extractions and Biological Activities of Medicinal Plants)
  • Feature Paper
  • Article
  • Open Access
57 Citations
6,017 Views
22 Pages

Poly(vinyl alcohol)/Plant Extracts Films: Preparation, Surface Characterization and Antibacterial Studies against Gram Positive and Gram Negative Bacteria

  • Mihaela Barbălată-Mândru,
  • Diana Serbezeanu,
  • Maria Butnaru,
  • Cristina Mihaela Rîmbu and ,
  • Alexandru Alin Enache and
  • Magdalena Aflori
  • + 1 author+ 0 author

28 March 2022

In this study, we aim to obtain biomaterials with antibacterial properties by combining poly(vinyl alcohol) with the extracts obtained from various selected plants from Romania. Natural herbal extracts of freshly picked flowers of the lavender plant...

(This article belongs to the Section Biomaterials)
  • Article
  • Open Access
41 Citations
7,016 Views
27 Pages

Production of Verbascoside, Isoverbascoside and Phenolic Acids in Callus, Suspension, and Bioreactor Cultures of Verbena officinalis and Biological Properties of Biomass Extracts

  • Paweł Kubica,
  • Agnieszka Szopa,
  • Adam Kokotkiewicz,
  • Natalizia Miceli and ,
  • Maria Fernanda Taviano,
  • Alessandro Maugeri,
  • Santa Cirmi,
  • Alicja Synowiec,
  • Małgorzata Gniewosz and
  • Halina Ekiert
  • + 10 authors+ 5 authors

28 November 2020

Callus, suspension and bioreactor cultures of Verbena officinalis were established, and optimized for biomass growth and production of phenylpropanoid glycosides, phenolic acids, flavonoids and iridoids. All types of cultures were maintained on/in th...

(This article belongs to the Special Issue Plant Secondary Metabolites Isolation, Interaction and Biological Activities)
  • Article
  • Open Access
17 Citations
5,926 Views
18 Pages

Phenylpropanoid Glycoside and Phenolic Acid Profiles and Biological Activities of Biomass Extracts from Different Types of Verbena officinalis Microshoot Cultures and Soil-Grown Plant

  • Paweł Kubica,
  • Adam Kokotkiewicz,
  • Magdalena Anna Malinowska,
  • Alicja Synowiec and ,
  • Małgorzata Gniewosz,
  • Shah Hussain,
  • Muhammad Yaqoob,
  • Günther K. Bonn,
  • Thomas Jakschitz and
  • Agnieszka Szopa
  • + 10 authors+ 5 authors

17 February 2022

Different types of microshoot cultures (agar, stationary liquid, agitated, and bioreactors) of Verbena officinalis were optimized for biomass growth and the production of phenylpropanoid glycosides and phenolic acids. Using ultra-high performance liq...

  • Article
  • Open Access
21 Citations
4,917 Views
10 Pages

In Vitro Cultures of Some Medicinal Plant Species (Cistus × incanus, Verbena officinalis, Scutellaria lateriflora, and Scutellaria baicalensis) as a Rich Potential Source of Antioxidants—Evaluation by CUPRAC and QUENCHER-CUPRAC Assays

  • Michał Dziurka,
  • Paweł Kubica,
  • Inga Kwiecień,
  • Jolanta Biesaga-Kościelniak and ,
  • Halina Ekiert,
  • Shaimaa A. M. Abdelmohsen,
  • Fatemah F. Al-Harbi,
  • Diaa O. El-Ansary,
  • Hosam O. Elansary and
  • Agnieszka Szopa
  • + 5 authors+ 0 author

27 February 2021

Comparative estimations of the antioxidant activity of methanolic extracts from biomasses of different types of in vitro cultures of Cistus × incanus, Verbena officinalis, Scutellaria lateriflora, and S. baicalensis and also from plant raw materials...

(This article belongs to the Special Issue Phenolic Composition and Antioxidant Activity of Plant Extracts)
  • Article
  • Open Access
6 Citations
2,767 Views
25 Pages

New Antimicrobial Gels Based on Clove Essential Oil–Cyclodextrin Complex and Plant Extracts for Topical Use

  • Alina Ionela Stancu,
  • Lia Mara Dițu,
  • Eliza Oprea,
  • Anton Ficai and ,
  • Irinel Adriana Badea,
  • Mihaela Buleandră,
  • Oana Brîncoveanu,
  • Anca Gabriela Mirea,
  • Sorina Nicoleta Voicu and
  • Magdalena Mititelu
  • + 8 authors+ 3 authors

18 August 2025

This study aimed to develop and characterise novel hydrogels based on natural bioactive compounds for topical antimicrobial applications. Four gel systems were formulated using different polymers, namely polyacrylic acid (Carbopol 940, CBP-G), chitos...

(This article belongs to the Special Issue Hydrogels, Microgels, and Nanogels: From Fundamentals to Applications (3rd Edition))
  • Article
  • Open Access
20 Citations
6,661 Views
17 Pages

Chemical Composition and Antioxidant Properties of Common and Lemon Verbena

  • Milena Polumackanycz,
  • Spyridon Alexandros Petropoulos,
  • Mikel Añibarro-Ortega,
  • José Pinela and ,
  • Lillian Barros,
  • Alina Plenis and
  • Agnieszka Viapiana
  • + 2 authors+ 0 author

15 November 2022

The nutritional profiles of common and lemon verbena leaves were analyzed (proximate constituents, free sugars, organic acids, tocopherols, and fatty acids) and the leaves were prepared in hydromethanolic and aqueous (decoctions and infusions) extrac...

  • Article
  • Open Access
171 Citations
15,965 Views
15 Pages

Phytotoxic Activities of Mediterranean Essential Oils

  • Luiz Fernando Rolim De Almeida,
  • Fernando Frei,
  • Emilia Mancini,
  • Laura De Martino and
  • Vincenzo De Feo

14 June 2010

Twelve essential oils from Mediterranean aromatic plants were tested for their phytotoxic activity, at different doses, against the germination and the initial radicle growth of seeds of Raphanus sativus, Lactuca sativa and Lepidium sativum. The esse...

  • Article
  • Open Access
40 Citations
6,451 Views
14 Pages

Citral-Containing Essential Oils as Potential Tyrosinase Inhibitors: A Bio-Guided Fractionation Approach

  • Francesca Capetti,
  • Massimo Tacchini,
  • Arianna Marengo,
  • Cecilia Cagliero and ,
  • Carlo Bicchi,
  • Patrizia Rubiolo and
  • Barbara Sgorbini
  • + 2 authors+ 0 author

13 May 2021

Excessive melanin production causes serious dermatological conditions as well as minor aesthetic problems (i.e., freckles and solar lentigo). The downregulation of tyrosinase is a widespread approach for the treatment of such disorders, and plant ext...

(This article belongs to the Special Issue Chemical Profiling and Biological Activity of Plant Natural Compounds)
  • Article
  • Open Access
3 Citations
1,417 Views
17 Pages

Bioactive Aromatic Plant Extracts Modulate Metabolism and Inflammation in HeLa Cells

  • Sara Silva,
  • Manuela Machado,
  • Manuela Pintado and
  • Eduardo M. Costa

14 November 2025

Aromatic plants are rich sources of bioactive compounds with recognized therapeutic potential. This study investigated the phytochemical composition and biological activities of ethanolic extracts from four aromatic species—Thymus vulgaris L. (...

(This article belongs to the Special Issue Advances and Opportunities of Natural Products in Drug Discovery)
  • Article
  • Open Access
311 Views
24 Pages

Metabolomic Fingerprinting and UHPLC-ESI-HRMS/MS Profiling of Five Medicinal Plants Associated with Wound Care

  • Iskra Davkova Stojanovski,
  • Uroš Gašić,
  • Danijela Mišić,
  • Ana Trajkovska Matevska and ,
  • Veronika Stoilkovska Gjorgievska,
  • Filip Todorov,
  • Ivana Cvetkovikj Karanfilova,
  • Gjoshe Stefkov and
  • Marija Karapandzova
  • + 4 authors+ 0 author

15 October 2026

Chronic wounds remain a challenging medical problem due to the involvement of multiple biological processes that can delay normal tissue repair. Medicinal plants may contain diverse bioactive compounds with potential relevance for wound management. H...

(This article belongs to the Special Issue Bioactive Natural Products from Plants: Extraction, Characterization and Application)
  • Review
  • Open Access
198 Citations
45,014 Views
36 Pages

22 October 2023

Natural ingredients have been used for centuries for skin treatment and care. Interest in the health effects of plants has recently increased due to their safety and applicability in the formulation of pharmaceuticals and cosmetics. Long-known plant...

(This article belongs to the Section Molecular Plant Sciences)
  • Article
  • Open Access
5 Citations
3,003 Views
9 Pages

Verbenalin Reduces Amyloid-Beta Peptide Generation in Cellular and Animal Models of Alzheimer’s Disease

  • Juhee Lim,
  • Seokhee Kim,
  • Changhyun Lee,
  • Jeongwoo Park and ,
  • Gabsik Yang and
  • Taehan Yook
  • + 1 author+ 0 author

8 December 2022

Verbenalin, among the major constituents of Verbena officinalis, has been reported to exhibit sleep-promoting and antioxidant activities. This study demonstrates the effects of verbenalin on amyloid-beta (Aβ) peptide generation in Swedish mutant...

(This article belongs to the Special Issue Natural Compounds for Disease and Health)
  • Article
  • Open Access
92 Citations
12,218 Views
11 Pages

In Vitro Control of Post-Harvest Fruit Rot Fungi by Some Plant Essential Oil Components

  • Ippolito Camele,
  • Luciana Altieri,
  • Laura De Martino,
  • Vincenzo De Feo and ,
  • Emilia Mancini and
  • Gian Luigi Rana
  • + 1 author+ 0 author

21 February 2012

Eight substances that are main components of the essential oils from three Mediterranean aromatic plants (Verbena officinalis, Thymus vulgaris and Origanum vulgare), previously found active against some phytopathogenic Fungi and Stramenopila, have be...

  • Article
  • Open Access
4 Citations
3,136 Views
14 Pages

Organic Medicinal and Aromatic Plants: Consumption Profile of a Portuguese Consumer Sample

  • Ana Mendes,
  • André Oliveira,
  • Jorge Lameiras,
  • Pedro Mendes-Moreira and
  • Goreti Botelho

16 November 2023

The production and consumption of organic products have been increasing in Portugal, as well as in the European Union as a whole. The main objective of this work is to understand the consumption habits of organic medicinal and aromatic plants (OMAPs)...

(This article belongs to the Section Plant Foods)
  • Article
  • Open Access
37 Citations
7,824 Views
16 Pages

Antimicrobial Activity of Essential Oils against Staphylococcus and Malassezia Strains Isolated from Canine Dermatitis

  • Valentina Virginia Ebani,
  • Fabrizio Bertelloni,
  • Basma Najar,
  • Simona Nardoni and ,
  • Luisa Pistelli and
  • Francesca Mancianti
  • + 1 author+ 0 author

Staphylococcus spp. bacteria are the most frequently involved agents in canine cutaneous infections. Treatment of these infections is based on antibiotic therapy, that often is not effective because of the antibiotic-resistance of the bacterial strai...

(This article belongs to the Special Issue Biology and Pathogenesis of Staphylococcus Infection)