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Extractions and Biological Activities of Medicinal Plants

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 30 November 2026 | Viewed by 486

Editor


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Guest Editor
Department of Biology, Josip Juraj Strossmayer University of Osijek, Ulica Cara Hadrijana 8/a, 31000 Osijek, Croatia
Interests: antioxidant activity of plant extracts; phytochemicals; oxidative stress; lipid peroxidation; antibacterial activity; bioactive heterocyclic compounds
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Medicinal plants represent an important source of biologically active compounds, with significant potential in pharmaceutical, nutraceutical, and biomedical applications. Advances in extraction techniques and analytical methods have enabled more efficient isolation and characterization of phytochemicals with antioxidant, antimicrobial, anti-inflammatory, and other beneficial biological activities. At the same time, there is increasing interest in sustainable and green extraction approaches that minimize environmental impact while maximizing the recovery of valuable bioactive compounds.

This Special Issue aims to highlight recent advances in the extraction, characterization, and biological evaluation of compounds derived from medicinal plants. Contributions focusing on innovative extraction technologies, phytochemical profiling, bioactivity assessment, and potential applications of plant-derived compounds in medicine, food science, and biotechnology are particularly welcome. Both experimental studies and comprehensive reviews addressing the biological potential of medicinal plants are encouraged.

Prof. Dr. Valentina Pavic
Guest Editor

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • medicinal plants
  • plant extracts
  • bioactive compounds
  • antioxidant activity
  • antimicrobial activity
  • phytochemicals

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Published Papers (1 paper)

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Research

19 pages, 3559 KB  
Article
Systematic Identification of Chemical Components and Analysis of Major Constituents of Verbena officinalis L. Based on UHPLC–Q–Exactive–Orbitrap MS Combined with Feature-Based Molecular Networking and SIRIUS Strategy
by Wenqing Xiao, Meng Li, Huibin Luo, Qiru Chen, Liangyin Shu, Liangjun Guan and Shunli Xiao
Molecules 2026, 31(13), 2244; https://doi.org/10.3390/molecules31132244 - 25 Jun 2026
Viewed by 138
Abstract
Verbena officinalis L., a classic medicinal plant of the Verbenaceae family with wide clinical applications, contains alkaloids and steroids with potent anti-inflammatory and anti-psoriatic activities. However, its whole-plant chemical composition and pharmacological material basis have not been systematically elucidated. Here, UHPLC–Q–Exactive–Orbitrap MS combined [...] Read more.
Verbena officinalis L., a classic medicinal plant of the Verbenaceae family with wide clinical applications, contains alkaloids and steroids with potent anti-inflammatory and anti-psoriatic activities. However, its whole-plant chemical composition and pharmacological material basis have not been systematically elucidated. Here, UHPLC–Q–Exactive–Orbitrap MS combined with FBMN and SIRIUS software was applied for comprehensive component analysis. A total of 126 constituents were annotated following MSI standards: 15 were unambiguously identified as MSI Level 1 using reference standards, 80 were tentatively assigned to MSI Level 2 via literature MS/MS data and GNPS spectral matching, and the remaining 31 were annotated as MSI Level 3 by in silico prediction with SIRIUS. Among them, 74 compounds were detected in this plant for the first time, and 15 were preliminarily regarded as putative novel candidate constituents. This integrated method shows better isomer resolution than traditional GNPS workflows, greatly improving the efficiency and accuracy of chemical profiling of medicinal plants. Full article
(This article belongs to the Special Issue Extractions and Biological Activities of Medicinal Plants)
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