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41 Results Found

  • Article
  • Open Access
3 Citations
2,838 Views
12 Pages

Influence of Thermal and Mechanical Load Cycling on Fracture Resistance of Premolars Filled with Calcium Silicate Sealer

  • Ahlam Smran,
  • Mariam Abdullah,
  • Norasmatul Akma Ahmad,
  • Nassr AL-Maflehi and
  • Abdulaziz Samran

30 March 2023

The aim of this study was to evaluate the aging effect of thermomechanical cyclic load on fracture resistance of lower premolars obturated with AH Plus and BioRoot RCS root canal sealers. Forty-eight single-rooted premolars teeth were instrumented wi...

  • Article
  • Open Access
1 Citations
2,944 Views
15 Pages

5 November 2025

Successful endodontic treatment relies on effective shaping, disinfection and obturation. Calcium silicate sealers such as BioRoot™ RCS show promise due to their bioactivity and sealing properties, but more clinical evidence using standardized...

  • Feature Paper
  • Article
  • Open Access
35 Citations
4,336 Views
10 Pages

Debunking the Concept of Dentinal Tubule Penetration of Endodontic Sealers: Sealer Staining with Rhodamine B Fluorescent Dye Is an Inadequate Method

  • David Donnermeyer,
  • Sina Schmidt,
  • Arno Rohrbach,
  • Johannes Berlandi,
  • Sebastian Bürklein and
  • Edgar Schäfer

10 June 2021

The aim of this study was to investigate the suitability of rhodamine B dye staining of an epoxy resin sealer (AH Plus) and calcium-silicate-based sealers (Total Fill BC Sealer, BioRoot RCS) to represent the penetration depth of the sealers into dent...

  • Article
  • Open Access
14 Citations
2,736 Views
9 Pages

10 June 2021

The objective of this study was to assess the porosity distribution of BioRoot RCS/single gutta-percha point root-canal fillings performed by a general dental practitioner and endodontist. Fourteen plastic models of maxillary premolars with two roots...

  • Article
  • Open Access
7 Citations
3,302 Views
11 Pages

5 March 2021

The present study evaluated the obturation quality of root canals filled with BioRoot RCS sealer and single gutta-percha point by undergraduate student (US), postgraduate student (PS) and endodontist (ED). Twenty-one plastic models of upper premolars...

  • Article
  • Open Access
5 Citations
2,548 Views
8 Pages

Duration of Immersion and Type of Immersion Solution Distort the Outcome of Push-Out Bond Strength Testing Protocols

  • David Donnermeyer,
  • Lena Göbell,
  • Sebastian Bürklein,
  • Till Dammaschke and
  • Edgar Schäfer

5 September 2019

This study aimed to investigate the influence of immersion duration and the type of immersion solution on the outcome of push-out bond strength (POBS) tests. Root canals of 120 straight single-rooted teeth were instrumented to a diameter of 1.5 mm an...

  • Feature Paper
  • Article
  • Open Access
12 Citations
5,017 Views
9 Pages

28 May 2019

The present study evaluated the porosity distribution of BioRoot RCS/single gutta-percha point (BR/SC) and MTA flow (MF) fillings, which were used as plugs for the apical perforation repair in curved canals of extracted mandibular molars using micro-...

  • Article
  • Open Access
8 Citations
2,931 Views
11 Pages

27 October 2021

The present study evaluated the effect of ultrasonic agitation on the porosity distribution of BioRoot RCS/single gutta-percha cone (BR/SC) and MTA Flow (MF) root canals fillings used as apical plugs in moderately curved and apically perforated roots...

  • Article
  • Open Access
62 Citations
5,721 Views
7 Pages

Cytotoxicity of Different Concentrations of Three Root Canal Sealers on Human Mesenchymal Stem Cells

  • Sara A. Alsubait,
  • Reem Al Ajlan,
  • Hala Mitwalli,
  • Nour Aburaisi,
  • Amer Mahmood,
  • Manikandan Muthurangan,
  • Randa Almadhri,
  • Musaad Alfayez and
  • Sukumaran Anil

This study assessed the dose-dependent effect on the cytotoxicity of BioRoot RCS (BR) and Endosequence BC (BC) sealers in human bone marrow mesenchymal stem cells (hMSCs) compared to those of the AH Plus sealer. Cells were exposed to different diluti...

  • Article
  • Open Access
30 Citations
3,963 Views
11 Pages

Physico-Chemical Investigation of Endodontic Sealers Exposed to Simulated Intracanal Heat Application: Hydraulic Calcium Silicate-Based Sealers

  • David Donnermeyer,
  • Magdalena Ibing,
  • Sebastian Bürklein,
  • Iris Weber,
  • Maximilian P. Reitze and
  • Edgar Schäfer

4 February 2021

The aim of this study was to gain information about the effect of thermal treatment of calcium silicate-based sealers. BioRoot RCS (BR), Total Fill BC Sealer (TFBC), and Total Fill BC Sealer HiFlow (TFHF) were exposed to thermal treatment at 37 °C, 4...

  • Article
  • Open Access
2 Citations
4,859 Views
10 Pages

Antibiofilm Efficacy of Calcium Silicate-Based Endodontic Sealers

  • Matilde Ruiz-Linares,
  • Vsevolod Fedoseev,
  • Carmen Solana,
  • Cecilia Muñoz-Sandoval and
  • Carmen María Ferrer-Luque

8 August 2024

Background: Using endodontic sealers with long-term antimicrobial properties can increase the success of endodontic treatment. This study aimed to assess the antimicrobial activity over time of two calcium silicate (CS)-based sealers, AH Plus Biocera...

  • Article
  • Open Access
19 Citations
6,564 Views
15 Pages

Antimicrobial Effectiveness of Calcium Silicate Sealers against a Nutrient-Stressed Multispecies Biofilm

  • Rahul Bose,
  • Konstantinos Ioannidis,
  • Federico Foschi,
  • Abdulaziz Bakhsh,
  • Robert D. Kelly,
  • Sanjukta Deb,
  • Francesco Mannocci and
  • Sadia Ambreen Niazi

24 August 2020

Purpose: This study compared the antimicrobial efficacy of calcium silicate sealers (BioRoot RCS and Total Fill BC) and conventional sealers (AH Plus and Tubli-seal) against planktonic bacteria and a nutrient-stressed multispecies biofilm. Methods: A...

  • Article
  • Open Access
12 Citations
3,407 Views
15 Pages

22 April 2024

Introduction: We compared the effects of heat on the physicochemical properties of recently developed calcium silicate-based sealers (CSBSs), including BioRoot Flow, BioRoot RCS, and AH Plus Bioceramic sealer, with those of the epoxy-resin-based seal...

  • Article
  • Open Access
1,434 Views
18 Pages

Background: The primary objective of this study was to evaluate the cytotoxic and genotoxic effects of calcium silicate-based sealers (BioRoot RCS and MTA Fillapex) compared to an epoxy-based sealer (AH Plus). Materials and methods: The study was con...

  • Article
  • Open Access
17 Citations
4,017 Views
11 Pages

Impact of Immersion Media on Physical Properties and Bioactivity of Epoxy Resin-Based and Bioceramic Endodontic Sealers

  • Thais Gomes de Moraes,
  • Alan Silva de Menezes,
  • Renata Grazziotin-Soares,
  • Rafael Ubaldo Moreira e Moraes,
  • Paulo Vitor Campos Ferreira,
  • Ceci Nunes Carvalho,
  • Jose Bauer and
  • Edilausson Moreno Carvalho

14 February 2022

This study assessed the effects of immersion media [distilled water (dw), phosphate buffered saline (pbs) and simulated body fluid (sbf)] in the physical properties [fluid uptake/sorption/solubility and alkalinization activity (pH)] and bioactivity o...

  • Feature Paper
  • Article
  • Open Access
64 Citations
7,151 Views
12 Pages

5 August 2019

The purpose of this study was to compare the cytotoxic effects and mineralization activity of three calcium silicate-based root canal sealers to those of a conventional resin-based sealer. Experiments were performed using human dental pulp stem cells...

  • Article
  • Open Access
2,235 Views
13 Pages

Push-Out Bond Strength of Three Bioceramic Sealers to Root Canal Dentin After Different Irrigation Protocols

  • Zoran Urošević,
  • Violeta Petrović,
  • Ivana Milanović,
  • Vojislav Komlenić,
  • Tatjana Savić-Stanković and
  • Jugoslav Ilić

26 August 2025

The adhesion of endodontic sealers to dentin may be influenced both by the chemical composition of the sealer and the final irrigation protocol. The aim of this study was to examine the push-out bond strength of three differently formulated biocerami...

  • Article
  • Open Access
5 Citations
3,572 Views
13 Pages

Comparative Analysis of the Filling Capacity of Simulated Lateral Canals of Two Bioactive Root Canal Sealers Using Warm Gutta-Percha Technique

  • Jesús Mena-Álvarez,
  • Juliette Theophanie Sevrain,
  • Mario Zorita-García and
  • Cristina Rico-Romano

7 July 2021

The aim of this study was to evaluate ex vivo the sealing achieved at simulated lateral canals (SLC) and the quality of filling according to their position in the root canal after using the same filling technique. SLC were created at three levels in...

  • Article
  • Open Access
36 Citations
6,414 Views
11 Pages

11 February 2019

The purpose of this study was to compare the penetration ability of calcium silicate root canal sealers and conventional resin-based sealer using confocal laser scanning microscopy (CLSM). A total of 60 recently extracted single-rooted human premolar...

  • Article
  • Open Access
12 Citations
4,241 Views
14 Pages

A Micro-CT Analysis of Initial and Long-Term Pores Volume and Porosity of Bioactive Endodontic Sealers

  • Mateusz Radwanski,
  • Michal Leski,
  • Adam K. Puszkarz,
  • Jerzy Sokolowski,
  • Louis Hardan,
  • Rim Bourgi,
  • Salvatore Sauro and
  • Monika Lukomska-Szymanska

26 September 2022

The evaluation of the porosities within the interface of root canals obturated with endodontics materials is extremely important for the long-term success of endodontic treatments. The aim of this study was to compare initial and long-term volume of...

  • Article
  • Open Access
2 Citations
1,429 Views
14 Pages

Physico-Chemical Properties and Push-Out Bond Strength to Root Dentine of Calcium Silicate-Based Sealers

  • Ivana Milanovic,
  • Vesna Miletic,
  • Bojan Dzeletovic,
  • Djordje Antonijevic,
  • Tatjana Savic Stankovic,
  • Danilo Pavlovic,
  • Ana Despotovic and
  • Violeta Petrovic

The calcium silicate-based sealers currently available on the market have different compositions and formulations, which is why their physical and chemical properties may vary. (1) The aim of the study was to measure the physico-chemical properties o...

  • Article
  • Open Access
4 Citations
2,535 Views
19 Pages

Microstructural and Elemental Characterization of Calcium Silicate-Based Sealers

  • Mateusz Radwanski,
  • Ireneusz Piwonski,
  • Tomasz Szmechtyk,
  • Salvatore Sauro and
  • Monika Lukomska-Szymanska

Calcium silicate-based sealers (CSBS) vary in chemical composition, which can influence treatment outcomes. Therefore, the study aimed at comparing several commercially available CSBS regarding microstructure and elemental characterization. Four CSBS...

  • Article
  • Open Access
2 Citations
3,000 Views
14 Pages

Comparison of Apical Microleakage in Bioceramic and Resin-Based Endodontic Sealers with Conventional and Bioceramic Surface-Impregnated Gutta-Percha Points

  • Lucia Somolová,
  • Yuliya Morozova,
  • Iva Voborná,
  • Matej Rosa,
  • Barbora Novotná,
  • Pavel Holík and
  • Kateřina Langová

The aim of this study is to evaluate the apical sealing ability of novel bioceramic-based (BCB) and widely used resin-based (RB) root canal sealers in combination with traditional or bioceramic-coated gutta-percha points. A total of 92 human single-r...

  • Article
  • Open Access
5 Citations
2,926 Views
14 Pages

6 March 2023

The currently available bioceramic-based sealers still demonstrate low bond strength with a poor seal in root canal despite desirable biological properties. Hence, the present study aimed to determine the dislodgment resistance, adhesive pattern, and...

  • Article
  • Open Access
3 Citations
2,640 Views
12 Pages

Medium- and Long-Term Re-Treatment of Root Canals Filled with a Calcium Silicate-Based Sealer: An Experimental Ex Vivo Study

  • Giulia Bardini,
  • Elisabetta Cotti,
  • Terenzio Congiu,
  • Claudia Caria,
  • Davide Aru and
  • Montse Mercadè

13 May 2022

This study investigated the possibility of re-treating a calcium silicate-based sealer (CSBS), compared to an epoxy-resin sealer (RBS), using rotary instrumentation at different times from obturation (1 month/1 year). Thirty-six human mandibular prem...

  • Article
  • Open Access
19 Citations
5,199 Views
11 Pages

11 October 2021

The conditioning of the root canal wall during chemo-mechanical root canal treatment differentially affects the adhesion of root canal sealers. This investigation evaluated the impact of sodium hypochlorite (NaOCl) concentration as used in a root can...

  • Systematic Review
  • Open Access
5 Citations
2,563 Views
12 Pages

Effect of Plasma Treatment on Root Canal Sealers’ Adhesion to Intraradicular Dentin—A Systematic Review

  • Inês Ferreira,
  • Cláudia Lopes,
  • Armando Ferreira,
  • Filipe Vaz,
  • Irene Pina-Vaz and
  • Benjamín Martín-Biedma

27 July 2023

This investigation aimed to assess, through a systematic review, the effect of non-thermal plasma treatments on root canal sealers’ adhesion to dentin. This study followed the 2020 Preferred Reporting Items for Systematic Reviews and Meta-Analy...

  • Article
  • Open Access
22 Citations
3,839 Views
10 Pages

Could the Calcium Silicate-Based Sealer Presentation Form Influence Dentinal Sealing? An In Vitro Confocal Laser Study on Tubular Penetration

  • Paula Muedra,
  • Leopoldo Forner,
  • Adrián Lozano,
  • José L. Sanz,
  • Francisco J. Rodríguez-Lozano,
  • Julia Guerrero-Gironés,
  • Francesco Riccitiello,
  • Gianrico Spagnuolo and
  • Carmen Llena

31 January 2021

Dentinal tubule penetration influences root canal treatment sealing. The aim of this study was to compare dentinal penetration of two clinical presentations of silicate-based sealers using confocal laser. Sixty single-rooted human teeth from 50–70 ye...

  • Article
  • Open Access
1 Citations
1,173 Views
10 Pages

21 November 2025

Background/Objectives: The clinical outcome of root canal treatments using calcium silicate-based sealer (CSBS) remains unclear. This study aimed to evaluate the 1-year effect of CSBS in combination with a single-cone obturation technique on periapic...

  • Article
  • Open Access
11 Citations
2,780 Views
11 Pages

15 March 2024

Hydraulic calcium silicate-based (HCS) sealers have recently gained tremendous popularity due to their unique properties. However, their removal during endodontic retreatment is challenging. The solvent, which could chemically deteriorate the materia...

  • Article
  • Open Access
5 Citations
2,038 Views
11 Pages

Evaluation of Cytotoxicity, Cell Attachment, and Elemental Characterization of Three Calcium Silicate-Based Sealers

  • Anahi de Paula Melo,
  • Camila Maria Peres de Rosatto,
  • Danilo Cassiano Ferraz,
  • Gabriela Leite de Souza and
  • Camilla Christian Gomes Moura

16 October 2023

We investigated three calcium silicate-based sealers with respect to their chemical characterization, cytotoxicity, and attachment to RAW264.7 cells. BioRoot RCS (BR), Bio-C Sealer (BC), and Sealer Plus BC (SPBC) were assessed using Fourier transform...

  • Article
  • Open Access
10 Citations
2,984 Views
12 Pages

Immediate and Long-Term Radiopacity and Surface Morphology of Hydraulic Calcium Silicate-Based Materials

  • Goda Bilvinaite,
  • Saulius Drukteinis,
  • Vilma Brukiene and
  • Sivaprakash Rajasekharan

24 September 2022

The present study aimed to evaluate and compare the radiopacity and surface morphology of AH Plus Bioceramic Sealer (AHPB), Bio-C Sealer (BIOC), Biodentine (BD), BioRoot RCS (BR), Grey-MTAFlow (GMF), White-MTAFlow (WMF), TotalFill BC Sealer (TF), and...

  • Article
  • Open Access
212 Views
17 Pages

Effect of Different Chemo-Mechanical Shaping Protocols on the Intratubular Penetration of a Bioceramic Sealer

  • Luigi Generali,
  • Federica Veneri,
  • Carlo Gaeta,
  • Francesco Cavani,
  • Emanuele Ambu,
  • Sara Bertucci,
  • Giuseppina Vallotto,
  • Tommaso Filippini and
  • Eugenio Pedullà

1 February 2026

Background: This study aimed to evaluate the effect of two shaping systems combined with different irrigant activation methods on the tridimensional distribution of a bioceramic root canal sealer. Methods: Sixty single, round, straight root canals fr...

  • Article
  • Open Access
79 Citations
8,589 Views
9 Pages

13 March 2020

Background: The aim of this study was to compare the success rate of root canal treatments undertaken using a calcium silicate root canal sealer in combination with a single cone with non-calcium silicate cement and warm vertical condensation. Method...

  • Article
  • Open Access
6 Citations
4,320 Views
7 Pages

In Vitro Antibacterial Activity of Different Bioceramic Root Canal Sealers

  • Alberto Dagna,
  • Marco Colombo,
  • Claudio Poggio,
  • Gianluigi Russo,
  • Matteo Pellegrini,
  • Giampiero Pietrocola and
  • Riccardo Beltrami

1 November 2022

Bioceramic root canal sealers have been introduced in clinical dental use, but less is known about the antibacterial activity against Streptococcus mutans, Streptococcus salivarius, and Streptococcus sanguis. The purpose of the study is to compare ne...

  • Article
  • Open Access
19 Citations
4,106 Views
11 Pages

The Effect of Sealer Application Methods on Voids Volume after Aging of Three Calcium Silicate-Based Sealers: A Micro-Computed Tomography Study

  • Amre R. Atmeh,
  • Rakan Alharbi,
  • Ibrahim Aljamaan,
  • Abdulrahman Alahmari,
  • Ashwin C. Shetty,
  • Ahmed Jamleh and
  • Imran Farooq

14 March 2022

During obturation, air voids are undesirable as they may provide shelter for microorganisms or passage for fluids. This study aimed to compare the occurrence of voids between three calcium silicate-based sealers (CSBSs) (MTA-Fillapex, BioRoot-RCS, Bi...

  • Article
  • Open Access
16 Citations
4,049 Views
15 Pages

Evaluation of Bond Strength of Four Different Root Canal Sealers

  • Sanda Ileana Cimpean,
  • Adela Loredana Colceriu Burtea,
  • Radu Stefan Chiorean,
  • Mircea Cristian Dudescu,
  • Aurora Antoniac,
  • Alina Robu,
  • Radu Septimiu Campian and
  • Lucia Iacobina Timis

17 July 2022

The purposes of the study were to evaluate the influence of the sealer’s chemical composition on the interfacial strength between root canal dentin and root filling material, for two different classes of endodontic sealers, and to assess their...

  • Article
  • Open Access
20 Citations
2,984 Views
19 Pages

Enhancing Maize Productivity and Soil Health under Salt Stress through Physiological Adaptation and Metabolic Regulation Using Indigenous Biostimulants

  • Redouane Ouhaddou,
  • Abdelilah Meddich,
  • Chayma Ikan,
  • Rachid Lahlali,
  • Essaid Ait Barka,
  • Mohammad-Reza Hajirezaei,
  • Robin Duponnois and
  • Marouane Baslam

27 October 2023

Salinity poses a persistent threat to agricultural land, continuously jeopardizing global food security. This study aimed to enhance sweet corn (SC) fitness under varying levels of salinity using indigenous biostimulants (BioS) and to assess their im...

  • Article
  • Open Access
8 Citations
4,570 Views
15 Pages

Bio-Management of Root-Knot Nematodes on Cucumber Using Biocidal Effects of Some Brassicaceae Crops

  • Eman El-Remaly,
  • Ahmed A. Osman,
  • Hany G. Abd El-Gawad,
  • Fayez Althobaiti,
  • Sarah Albogami,
  • Eldessoky S. Dessoky and
  • Mohamed M. El-Mogy

Biofumigant and crop sequencing are effective and safe control system activators that maintain soil fertility and reduce pest populations. The study goals were to find new pesticide-free therapies for root-knot nematode management on cucumbers to mai...

  • Article
  • Open Access
126 Citations
9,709 Views
28 Pages

Evaluation of Six Algorithms to Monitor Wheat Leaf Nitrogen Concentration

  • Xia Yao,
  • Yu Huang,
  • Guiyan Shang,
  • Chen Zhou,
  • Tao Cheng,
  • Yongchao Tian,
  • Weixing Cao and
  • Yan Zhu

10 November 2015

The rapid and non-destructive monitoring of the canopy leaf nitrogen concentration (LNC) in crops is important for precise nitrogen (N) management. Nowadays, there is an urgent need to identify next-generation bio-physical variable retrieval algorith...

  • Article
  • Open Access
841 Views
15 Pages

The Effects of Different Crop Rotations on the Quality of Saline Soils in the Yinbei Plain

  • Jinmin Wu,
  • Bangyan Zhang,
  • Meiling Lin,
  • Rui Bu,
  • Xiaolong Bai,
  • Xiaoli Zhang,
  • Panting Liu and
  • Bin Wang

5 September 2025

Rice cultivation has the ability to ameliorate saline soils, but this monoculture pattern can lead to negative plant–soil feedback. In a previous study, we investigated the effects of long-term rice cultivation on saline soil chemistry, salt io...