Special Issues

Medicina publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Ophthalmology, Environment, and Lifestyle: New Pathways in Diagnosis and Treatment
edited by Jesús Merayo-Lloves and Rodrigo Martin Torres
submission deadline 20 Sep 2025 | Viewed by 108 | Submission Open
Keywords: vision science; ophthalmology; environment; lifestyle; aging
(This special issue belongs to the Section Ophthalmology)
New Developments in Diagnosis and Management of Breast Cancer
edited by Daliborca Cristina Vlad and
submission deadline 25 Sep 2025 | 5 articles | Viewed by 4572 | Submission Open
Keywords: breast cancer; diagnosis; management; therapy; targeted therapy; triple-negative breast cancer; screening; overall survival; prognosis; immunotherapy; surgery; new techniques; staging
(This special issue belongs to the Section Oncology)
Research on Allergy, Asthma, and Clinical Immunology
edited by Constantinos Pitsios and Athanassios Sinaniotis
submission deadline 25 Sep 2025 | 3 articles | Viewed by 2302 | Submission Open
Keywords: atopy; anaphylaxis; allergic rhinitis; asthma; atopic dermatitis; food allergy; eosinophilic esophagitis; drug allergy; hymenoptera venom; angioedema; urticaria; physical urticaria; mastocytosis
(This special issue belongs to the Section Hematology and Immunology)
New Regenerative Medicine Strategies in Oral Surgery
edited by Francesco Spadari, and
submission deadline 25 Sep 2025 | 1 articles | Viewed by 523 | Submission Open
Keywords: oral surgery; oral pathology; laser surgery; photobiomodulation
(This special issue belongs to the Section Dentistry and Oral Health)
Cutting-Edge Research into Cancer Radiotherapy
edited by Geert O.R.J. Janssens and
submission deadline 25 Sep 2025 | Viewed by 197 | Submission Open
Keywords: FLASH radiotherapy; image-guided radiotherapy; proton therapy; real-time imaging; tumor tracking; AI linear accelerators
(This special issue belongs to the Section Oncology)
New Insights into Heart Failure submission deadline 30 Sep 2025 | 7 articles | Viewed by 13346 | Submission Open
Keywords: heart failure; risk factors; treatment; device therapy; biomarkers; aging; cardiovascular disease; coronary artery disease; valvular heart disease; arrythmias; stroke; COPD; cancers; liver cirrhosis
(This special issue belongs to the Section Cardiology)
Insights and Advances in Cancer Biomarkers
edited by
submission deadline 30 Sep 2025 | 6 articles | Viewed by 6412 | Submission Open
Keywords: liquid biopsies; cancer biomarkers; cellular immunotherapy; single-cell sequencing; immune biomarkers; epigenetic markers; microbiome and metabolomics; proteomics; multiomics; machine learning; generative AI
(This special issue belongs to the Section Oncology)
New Insights into Neurodevelopmental Biology and Disorders
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 5840 | Submission Open
Keywords: neurodevelopment; neurodevelopmental biology; neurodevelopmental disorders; autism spectrum disorders (ASDs); down syndrome; ADHD; cerebral palsy; learning disability
(This special issue belongs to the Section Neurology)
AI in Imaging—New Perspectives, 2nd Edition
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 3127 | Submission Open
Keywords: artificial intelligence; imaging; machine learning; radiology; ethics; big data
(This special issue belongs to the Section Surgery)
State-of-the-Art Therapeutics and Imaging in Knee Surgery submission deadline 30 Sep 2025 | 2 articles | Viewed by 2960 | Submission Open
Keywords: knee surgery; minimally invasive techniques; regenerative medicine; diagnostic imaging modalities; MRI in knee surgery; CT and ultrasound imaging; novel surgical approaches; pharmacological treatments; patient outcomes; precision surgery; state-of-the-art therapies; clinical advancements; surgical precision; efficacy of knee treatments; robotic knee surgery; surgery-related costs; 3D-printing in knee surgery; novel surgical biomaterials; anatomical landmarks; knee morphometry
(This special issue belongs to the Section Surgery)
Recent Breakthroughs in the Diagnosis and Treatment of Oral Inflammatory Diseases submission deadline 30 Sep 2025 | 2 articles | Viewed by 2879 | Submission Open
Keywords: oral inflammatory diseases; multidisciplinary; clinical manifestation; diagnosis; treatment; clinical outcome
(This special issue belongs to the Section Dentistry and Oral Health)
Towards Improved Cancer Diagnosis: New Developments in Histopathology submission deadline 30 Sep 2025 | 4 articles | Viewed by 2540 | Submission Open
Keywords: histopathology; cancer diagnosis; digital pathology; molecular pathology; dermatopathology
(This special issue belongs to the Section Oncology)
Updates on Prevention of Acute Heart Failure
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 2025 | Submission Open
Keywords: acute heart failure; treatment of acute heart failure; management of acute heart failure; prevention of acute heart failure; chronic decompensated heart failure
(This special issue belongs to the Section Cardiology)
Hepato-Biliary-Pancreatic Surgery: Clinical Updates and Future Perspectives submission deadline 30 Sep 2025 | 3 articles | Viewed by 1976 | Submission Open
Keywords: HPB surgery; liver cancer; pancreatic cancer; biliary tract cancer
(This special issue belongs to the Section Surgery)
Advances in Corneal Management
edited by Sanja Masnec and Rafael I. Barraquer
submission deadline 30 Sep 2025 | 2 articles | Viewed by 1914 | Submission Open
Keywords: cornea; corneal disease; corneal transplantation; keratoconus; keratoplasty; penetrating keratoplasty; descemet stripping automated endothelial keratoplasty; deep anterior lamellar keratoplasty; descemet membrane endothelial keratoplasty; cross-linking; corneal infections; refractive surgery; photorefractive keratectomy; laser-assisted in situ keratomileusis; kerato– lenticule extraction; corneal imaging
(This special issue belongs to the Section Ophthalmology)
Surgical Approaches in Thyroid, Breast, and Other Endocrine Cancers: Advances and Challenges
edited by and Levan Tchabashvili
submission deadline 30 Sep 2025 | 2 articles | Viewed by 1363 | Submission Open
Keywords: endocrine surgery; breast cancer; thyroid diseases; surgical complications
(This special issue belongs to the Section Surgery)
Advances in Imaging and Diagnostics in Lung Disease: A Multimodal Approach
edited by Diana Manolescu and
submission deadline 30 Sep 2025 | 2 articles | Viewed by 1028 | Submission Open
Keywords: lung imaging; multimodal diagnostics; MRI; HRCT; lung ultrasound; pulmonary biomarkers; hybrid imaging; interstitial lung disease; AI in imaging; pulmonary medicine
(This special issue belongs to the Section Pulmonology)
Magnetic Resonance in Various Diseases and Biomedical Applications submission deadline 30 Sep 2025 | 1 articles | Viewed by 948 | Submission Open
Keywords: magnetic resonance imaging; MRI; magnetic resonance imaging biomarkers; neuroimaging; cancer imaging; abdominal imaging; pelvic imaging; musculoskeletal imaging; cardiac imaging; medical imaging; diffusion imaging; tensor imaging; functional imaging; magnetic resonance angiography
(This special issue belongs to the Section Infectious Disease)
Emerging Therapies for Gastric Cancer submission deadline 30 Sep 2025 | Viewed by 434 | Submission Open
Keywords: gastric cancer; oncology; therapies; individualized therapy; immunotherapy
(This special issue belongs to the Section Gastroenterology & Hepatology)
Current Advances in Foot and Ankle Surgery
edited by Min Gyu Kyung and Dong-Oh Lee
submission deadline 30 Sep 2025 | Viewed by 329 | Submission Open
Keywords: orthopedics; foot and ankle; osteoarthritis; trauma; gait analysis; advances; diagnosis; treatment; prognosis
(This special issue belongs to the Section Orthopedics)
Clinical and Surgical Updates on Bariatric Surgery submission deadline 30 Sep 2025 | Viewed by 263 | Submission Open
Keywords: bariatric surgery; morbid obesity; sleeve gastrectomy; gastric bypass; surgical complications; diabetes remission; hypertension remission; hypercholesterolemia remission; GERD; de novo GERD
Atrial Fibrillation and Heart Failure Management
edited by Erika Bertella
submission deadline 30 Sep 2025 | Viewed by 191 | Submission Open
Keywords: heart failure; cardiac magnetic resonance; cardiac computed tomography; echocardiography; atrial fibrillation; electrophysiology; surgery
(This special issue belongs to the Section Cardiology)
Advances in Structural Heart Diseases
edited by , and Erwan Donal
submission deadline 30 Sep 2025 | Viewed by 175 | Submission Open
Keywords: valvular heart diseases; transcatheter interventions; TEER; LAA closure; ASD closure; interventional echocardiography; multimodality cardiac imaging; three-dimensional echocardiography
(This special issue belongs to the Section Cardiology)
Advances in the Prevention, Diagnosis and Management of Surgical Complications After Kidney Transplantation submission deadline 30 Sep 2025 | Viewed by 140 | Submission Open
Keywords: kidney transplantation; bleeding; surgical site infection; post operative pain; incisional hernia; vascular complications; ureteric complications; prevention; surgical technology
(This special issue belongs to the Section Urology & Nephrology)
Recent Advances in Digestive Endoscopy submission deadline 30 Sep 2025 | Viewed by 114 | Submission Open
Keywords: digestive endoscopy; cholangiopancreatography; advanced endoscopy
(This special issue belongs to the Section Gastroenterology & Hepatology)
Prostate Cancer in the Molecular Era submission deadline 30 Sep 2025 | Viewed by 112 | Submission Open
Keywords: prostate cancer; precision medicine; molecular target; molecular oncology; tumor microenvironment; prognostic biomarker; predictive biomarker; liquid biopsy; precision medicine
(This special issue belongs to the Section Oncology)
Coronary Artery Disease from Acute Manifestation to Long Term Consequences submission deadline 1 Oct 2025 | 1 articles | Viewed by 890 | Submission Open
Keywords: coronary artery disease; acute coronary syndrome; coronary revascularization; coronary angiography; CT angiography; antiplatelet therapy; inflammation
(This special issue belongs to the Section Cardiology)
Peripheral Artery Disease in Thromboinflammation Era: Pathophysiological, Clinical and Therapeutic Implications submission deadline 1 Oct 2025 | Viewed by 115 | Submission Open
Keywords: thromboinflammation; peripheral artery disease; atherosclerosis; acute limb ischemia
(This special issue belongs to the Section Cardiology)
Modern Diagnostics and Therapy for Vitreoretinal Diseases submission deadline 10 Oct 2025 | 1 articles | Viewed by 1640 | Submission Open
Keywords: retinal pharmacotherapy; artificial intelligence; image recognition; optical coherence tomography; remote retinal monitoring; exudative retinal disease; geographic atrophy
(This special issue belongs to the Section Ophthalmology)
Clinical Updates and Future Perspectives on the Chronic Pain Management submission deadline 15 Oct 2025 | 1 articles | Viewed by 777 | Submission Open
Keywords: chronic pain management; pain assessment; regenerative medicine in pain management; multidisciplinary pain treatment; wearable technology in pain monitoring; personalized pain therapy
(This special issue belongs to the Section Neurology)
Revolutionizing Cardiopulmonary Resuscitation: Contemporary Advances and Challenges
edited by Georgios Mavrovounis, and
submission deadline 20 Oct 2025 | 2 articles | Viewed by 3672 | Submission Open
Keywords: cardiopulmonary resuscitation; defibrillation; mechanical CPR; emergency medicine; automated external defibrillator; e-CPR; post-resuscitation period; neurological outcomes
(This special issue belongs to the Section Intensive Care/ Anesthesiology)
Gut Microbiota and Gastrointestinal Cancer: Pathways to Progression and Opportunities for Intervention
edited by Vikas Kumar Somani, and
submission deadline 20 Oct 2025 | 1 articles | Viewed by 1721 | Submission Open
Keywords: gut microbiota; gastrointestinal cancer; dysbiosis; colorectal cancer; gastric cancer; pancreatic cancer; esophageal cancer; cancer progression; tumor microenvironment; inflammation; immune modulation; metabolic alterations; probiotics; prebiotics; microbial therapies; fecal microbiota transplantation; cancer immunotherapy; tumor-associated microbiome; gut– brain axis; microbiome modulation
(This special issue belongs to the Section Oncology)
Epidemiology of Geriatric Syndromes: Life Course Risk or Protective Factors
edited by Carlos Alfonso Reyes-Ortiz
submission deadline 25 Oct 2025 | Viewed by 435 | Submission Open
Keywords: older adults; geriatric syndromes; chronic disease; early life adversity; adverse childhood experiences; risk factors; protective factors
Pulmonary Fibrosis: Current Understanding and Future Directions
edited by Satoshi Okamori and
submission deadline 25 Oct 2025 | 1 articles | Viewed by 435 | Submission Open
Keywords: pulmonary fibrosis; interstitial lung disease (ILD); idiopathic pulmonary fibrosis (IPF); hypersensitivity pneumonitis; bronchoscopy; cryobiopsy; fibrotic lung disease; acute exacerbations; pleuroparenchymal fibroelastosis; rehabilitation; nutrition
(This special issue belongs to the Section Pulmonology)
Development and Application of Digestive Endoscopy
edited by , Sara Nikolic and
submission deadline 25 Oct 2025 | Viewed by 133 | Submission Open
Keywords: endoscopy; endoscopic ultrasound; interventional endoscopy; robotic endoscopy; gastroenterology; advanced imaging
(This special issue belongs to the Section Gastroenterology & Hepatology)
Advances in Pathogenesis, Rehabilitation, and Treatment of Knee Osteoarthritis
edited by and Magdalena-Rodica Trăistaru
submission deadline 25 Oct 2025 | Viewed by 106 | Submission Open
Keywords: pathogenesis; evidence based KOA; rehabilitation KOA; treatment KOA; surgery KOA
(This special issue belongs to the Section Orthopedics)
Multimodal Imaging Techniques in Myocardial Ischemia: Current Applications and Future Prospects
edited by Fausto Pizzino and Giovanni Concistrè
submission deadline 30 Oct 2025 | 3 articles | Viewed by 4833 | Submission Open
Keywords: myocardial ischemia; cardiac magnetic resonance; coronary computed tomography angiography; intravascular imaging; myocardial infarction with non-obstructive coronary arteries; ischemia with non-obstructive coronary arteries; coronary artery disease
(This special issue belongs to the Section Cardiology)
Advances and Perspectives in Esophageal Cancer Treatment
edited by Koji Otsuka and
submission deadline 30 Oct 2025 | Viewed by 2274 | Submission Open
Keywords: minimally invasive esophagectomy; robotic esophagectomy; locally advanced esophageal cancer; immunotherapy for esophageal cancer; cervical esophageal cancer; multidisciplinary approach to esophageal cancer
(This special issue belongs to the Section Surgery)
The Challenges and Prospects in Clinical Cardiology and Angiology
edited by Vincenzo Zaccone and
submission deadline 31 Oct 2025 | 6 articles | Viewed by 15168 | Submission Open
Keywords: cardiology; angiology; cardiovascular diseases; vascular health; diagnostic techniques; treatment strategies; translational research
(This special issue belongs to the Section Cardiology)
Current Advancements in Menopause Treatment and Management
edited by Richa Sood
submission deadline 31 Oct 2025 | 3 articles | Viewed by 9885 | Submission Open
Keywords: menopause; vasomotor symptoms; hormone therapy; tele-medicine; drug innovation; machine learning; artificial intelligence; cardiovascular; osteoporosis
(This special issue belongs to the Section Obstetrics and Gynecology)
Innovations in Amputation Care submission deadline 31 Oct 2025 | 4 articles | Viewed by 8725 | Submission Open
Keywords: bone-anchored prosthesis; targeted muscle reinnervation; amputation medicine; targeted sensory reinnervation; artificial intelligence; motor imagery; digital transformation; patient-reported outcome measurement
(This special issue belongs to the Section Orthopedics)
Future Trends in Breast Cancer Management submission deadline 31 Oct 2025 | 5 articles | Viewed by 8450 | Submission Open
Keywords: breast cancer; breast reconstruction; artificial intelligence; machine learning; staging; treatment; targeted therapy; digital pathology; radiomics; oncoplastic surgery; prognosis; immunotherapy; liquid biopsy
(This special issue belongs to the Section Oncology)
Advanced Technologies in Pediatric Nephrology
edited by Kiran K. Upadhyay
submission deadline 31 Oct 2025 | 3 articles | Viewed by 5042 | Submission Open
Keywords: pediatrics; kidney transplantation; dialysis; hypertension; nephrotic syndrome; glomerulonephritis; lupus nephritis; chronic kidney disease; voiding dysfunction; renal tubular disease
(This special issue belongs to the Section Pediatrics)
Gastric Sleeve Surgery: Techniques, Outcomes, and Future Directions
edited by Anna Maria Różańska-Walędziak and
submission deadline 31 Oct 2025 | 3 articles | Viewed by 4499 | Submission Open
Keywords: laparoscopic sleeve gastrectomy; bariatric surgery; obesity
(This special issue belongs to the Section Surgery)
Addressing the Changes and Innovations in the Treatment of Gynecological Cancers
edited by
submission deadline 31 Oct 2025 | 3 articles | Viewed by 4389 | Submission Open
Keywords: ovarian cancer; endometrial cancer; cervical cancer; minimally invasive surgery; adjuvant treatment; targeted therapy; immunotherapy; endoscopy
(This special issue belongs to the Section Oncology)
Diagnosis and Treatment of Valvular Heart Diseases
edited by and Ilaria Franzese
submission deadline 31 Oct 2025 | 3 articles | Viewed by 3344 | Submission Open
Keywords: valvular heart disease; aortic valve disease; mitral valve disease; tricuspid valve disease; pulmonary valve disease; transcatheter intervention; surgery
(This special issue belongs to the Section Cardiology)
Current Management and Future Challenges of Severe Traumatic Brain Injury
edited by Nasim Ahmed
submission deadline 31 Oct 2025 | 1 articles | Viewed by 2208 | Submission Open
Keywords: severe traumatic brain injury; computed tomography; magnetic resonance imaging; decompressive craniectomy; neurosurgical; trauma surgery; Surgical critical care; acute care surgery
(This special issue belongs to the Section Intensive Care/ Anesthesiology)
Transcatheter Therapies for Valvular Heart Disease
edited by and Basel Ramlawi
submission deadline 31 Oct 2025 | 3 articles | Viewed by 2163 | Submission Open
Keywords: aortic valve transcatheter interventions; mitral valve transcatheter interventions; tricuspid valve transcatheter interventions; pulmonary valve transcatheter interventions; transcatheter aortic valve intervention/replacement; mitral transcatheter edge-to-edge repair; transcatheter mitral valve replacement; percutaneous annuloplasty; tricuspid transcatheter edge-to-edge repair; transcatheter pulmonary valve replacement
(This special issue belongs to the Section Cardiology)
Progress in Venous Thromboembolism Research
edited by Mihaela Hostiuc
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1118 | Submission Open
Keywords: venous thromboembolism; cardiovascular disease; post-thrombotic syndrome; chronic thromboembolic pulmonary disease; prevention
Advances and Challenges in Prehospital Emergency Care
edited by Hayley L. Letson
submission deadline 31 Oct 2025 | 1 articles | Viewed by 580 | Submission Open
Keywords: prehospital; trauma; injury; traumatic brain injury; burns; cardiac arrest; stroke; rural/remote; emergency; resuscitation
(This special issue belongs to the Section Intensive Care/ Anesthesiology)
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