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Medicina
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Surgical Approaches in Thyroid, Breast, and Other Endocrine Cancers: Advances...
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Surgical Approaches in Thyroid, Breast, and Other Endocrine Cancers: Advances and Challenges

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Surgery".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 1278

Special Issue Editors

Dr. Francesk Mulita

E-Mail Website
Guest Editor
1. Department of Surgery, General Hospital of Eastern Achaia-Unit of Aigio, Aigio, Greece
2. Department of Surgery, University Hospital of Patras, 26504 Patras, Greece
Interests: general surgery; laparoscopic surgery; endocrine surgery; colorectal cancer; breast cancer
Special Issues, Collections and Topics in MDPI journals
Dr. Levan Tchabashvili

E-Mail Website
Guest Editor
Department of Surgery, General Hospital of Eastern Achaia-Unit of Aigio, Aigio, Greece
Interests: breast cancer; general surgery; breast surgery

Special Issue Information

Dear Colleagues,

Thyroid and breast carcinomas are now one of the most frequently diagnosed forms of cancers. Cancer diagnoses have evolved greatly in the past few decades, with novel biomarkers and genetic sequencing all being part of everyday medical practice in cancer diagnosis. Despite advances in the field of oncology and systematic treatment, surgery remains the cornerstone of cancer treatment with curative intent. Novel surgical techniques have evolved over the years to include robotic surgery, endoscopic excisions, and intraoperative visualization techniques for tumor localization, lymph node mapping, and perfusion assessment.

The scope of this Special Issue is to gather and present novel data regarding the newest operative techniques in cancer management, including but not limited to, malignant diseases. The focus of the Special Issue is on targeted surgical treatments and novel minimally invasive techniques in treating cancer and other surgical diseases. We welcome original articles on basic, pre-clinical, clinical, and translational research.

Dr. Francesk Mulita
Dr. Levan Tchabashvili
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • endocrine surgery
  • breast cancer
  • thyroid diseases
  • surgical complications

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Published Papers (2 papers)

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Research

8 pages, 272 KiB  
Article
Evaluation of the Necessity of Repeat Biopsy in Patients with Thyroid Nodules Classified as Atypia of Undetermined Significance (AUS) Based on Fine-Needle Aspiration Biopsy Results
by Yiğit Türk, Bahadır Emre Baki, Özer Makay, Gökhan İçöz and Murat Özdemir
Medicina 2025, 61(7), 1196; https://doi.org/10.3390/medicina61071196 - 30 Jun 2025
Viewed by 253
Abstract
Background and Objectives: The necessity of repeat fine-needle aspiration biopsy (FNAB) in nodules diagnosed as atypia of undetermined significance (AUS) remains debated. This study evaluates the role of a second FNAB in surgical decision making. Materials and Methods: A retrospective analysis was conducted [...] Read more.
Background and Objectives: The necessity of repeat fine-needle aspiration biopsy (FNAB) in nodules diagnosed as atypia of undetermined significance (AUS) remains debated. This study evaluates the role of a second FNAB in surgical decision making. Materials and Methods: A retrospective analysis was conducted on 131 patients (105 females and 26 males) who underwent surgery following an AUS diagnosis between 2020 and 2024. Patients were grouped based on whether surgery was performed after the first or second FNAB. Demographics, pathology, and ultrasound findings were compared. Results: Of the patients, 66 (50.7%) underwent surgery after the first FNAB and 65 (50.3%) after a second AUS diagnosis. Malignancy was detected in 47 out of 66 (71.2%) patients in the single biopsy group and in 44 out of 65 (67.7%) patients in the repeat biopsy group (p = 0.804). T1a tumors were more frequent in the first FNAB group (63.8% vs. 37.2%, p = 0.021). The EU-TIRADS classifications showed no significant differences. Conclusions: The malignancy rate observed (71.2%) exceeds reported rates in the literature, suggesting regional variability. Early-stage cancers were more frequent in patients operated on after the first FNAB, questioning the necessity of repeat biopsy and indicating a potential need to revise current guidelines. Full article
(This article belongs to the Special Issue Surgical Approaches in Thyroid, Breast, and Other Endocrine Cancers: Advances and Challenges)
11 pages, 1449 KiB  
Article
Racquet Mammoplasty as an Oncoplastic Technique in the Management of Lateral Quadrant Breast Cancer: A Prospective Controlled Study of Oncologic and Cosmetic Outcomes
by Amr G. Mohamed, Emad M. Abdelrahman, Sherief M. Mohsen, Mostafa S. Abdeen, Mohamed A. Elsayed, Zizi M. Ibrahim, Osama R. Abdelraouf and Ebtesam N. D. Attia
Medicina 2025, 61(3), 539; https://doi.org/10.3390/medicina61030539 - 19 Mar 2025
Viewed by 800
Abstract
Background and Objectives: The incorporation of oncoplastic surgery techniques into the management of breast cancer has become more popular and offers both oncological safety and good cosmetic results. However, it is challenging for surgeons to obtain good oncological control and acceptable cosmetic [...] Read more.
Background and Objectives: The incorporation of oncoplastic surgery techniques into the management of breast cancer has become more popular and offers both oncological safety and good cosmetic results. However, it is challenging for surgeons to obtain good oncological control and acceptable cosmetic results. This study aims to evaluate racquet mammoplasty in patients managing lateral quadrant breast tumors. Materials and Methods: In total, 59 female patients with lesions in their lateral breast quadrants were operated upon using the racquet mammoplasty technique. Their intraoperative data and postoperative outcomes were assessed and analyzed. Follow-up was planned for at least 1 year later. Results: In the current study, 59 females were enrolled, with a mean age of 38.6 ± 4.3 years. Tumors were located in the lateral upper quadrant in most of the patients (74.4%). The mean size of the tumors was 2.7 ± 1.8. The surgical margins were free of malignancy in all cases. A total of 5.1% of cases reported a wound infection. A single patient developed loco-regional recurrence. Concerning the cosmetic outcomes, 89.8% of patients reported excellent outcomes and none reported poor or bad results. Conclusions: The racquet mammoplasty technique, when used as an oncoplastic technique, provides oncological safety as well as good cosmetic results for tumors in the lateral breast quadrants. Full article
(This article belongs to the Special Issue Surgical Approaches in Thyroid, Breast, and Other Endocrine Cancers: Advances and Challenges)
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