Emerging Trends in the Neurosurgical Management of Neuroendocrine Tumors
A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Neurology".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 32
Special Issue Editors
Interests: neurosurgery; neurooncology; vascular neurosurgery; aneurysm; glioma, inovations
Interests: neurosurgery; neuro-oncology; cancer-predisposing syndrome; CMMRD
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neuroendocrine tumors (NETs) involving the central nervous system and skull base represent a rare but complex subset of cases in neurosurgical practice. While most NETs arise outside the CNS, advancements in systemic therapy and imaging have increased detection of intracranial metastases, paragangliomas, and primary neuroendocrine neoplasms of the pituitary and pineal region. Recent developments in functional imaging enable precise localization and surgical planning, particularly in cases where maximal safe resection is combined with stereotactic radiosurgery or peptide receptor radionuclide therapy (PRRT). Endoscopic endonasal approaches have revolutionized access to neuroendocrine tumors of the pituitary and skull base, improving outcomes and reducing morbidity. Similarly, microsurgical and neuromonitoring techniques have advanced the management of highly vascular paragangliomas in the foramen jugulare and spinal canal. Evolving WHO classifications underscore the neuroendocrine nature of certain CNS tumors, prompting new surgical strategies and multidisciplinary care models. This intersection of neurosurgery, neuro-oncology, and endocrine science presents a fertile ground for innovation.
We invite neurosurgeons, neuro-oncologists, and translational researchers to contribute original research and reviews to advance the understanding and surgical management of neuroendocrine tumors affecting the nervous system. Together, we can shape future standards of care in this challenging field.
Dr. Karol Wiśniewski
Dr. Bartosz Szmyd
Guest Editors
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Keywords
- neuroendocrine tumors
- central nervous system
- skull base surgery
- pituitary neuroendocrine tumors (PitNETs)
- paraganglioma
- brain metastases
- endoscopic endonasal approach
- microsurgery
- peptide receptor radionuclide therapy (PRRT)
- immunohistochemistry
- multidisciplinary management
- stereotactic radiosurgery
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