Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Innovations in Pathology and Viral Oncology
edited by Luca Roncati
submission deadline 17 Feb 2025 | Viewed by 197 | Submission Open
Keywords: pathology; viral oncology; gynecological oncology; hematological oncology; head and neck tumors; human papilloma virus (HPV); HPV-test; PAP-test; oncoviruses; cancer
(This special issue belongs to the Section Physiology and Pathology)
Research Update on Pancreaticobiliary Endotherapy
edited by Mateusz Jagielski
submission deadline 18 Feb 2025 | Viewed by 271 | Submission Open
Keywords: acute pancreatitis; chronic pancreatitis; pancreatic necrosis; pancreatic pseudocyst; endoscopic retrograde cholangiopancreatography (ERCP); endoscopic ultrasound (EUS); transpapillary drainage; transmural drainage; endoscopic necrosectomy
(This special issue belongs to the Section Medical Research)
Immuno-Pathogenesis Skin Diseases: Novel Molecular Targets and Biomarkers: 2nd Edition submission deadline 20 Feb 2025 | 2 articles | Viewed by 3846 | Submission Open
Keywords: chronic inflammatory skin diseases; immunopathogenesis; inflammatory pathways; molecular target; biomarkers; psoriasis; atopic dermatitis; hidradenitis suppurativa; urticaria; skin cancer
(This special issue belongs to the Section Physiology and Pathology)
Robot-Assisted Surgery: New Trends and Solutions
edited by and Felipe Boff Maegawa
submission deadline 20 Feb 2025 | 3 articles | Viewed by 3678 | Submission Open
Keywords: robotic surgery; minimally invasive abdominal surgery; minimally invasive liver surgery; minimally invasive pancreatic surgery
(This special issue belongs to the Section Medical Research)
Gynecological Endocrinology: From Physiological Mechanisms to Clinical Practice
edited by Ralitsa Robeva
submission deadline 20 Feb 2025 | 1 articles | Viewed by 1009 | Submission Open
Keywords: PCOS; hypothalamic amenorrhea; congenital adrenal hyperplasia; hypogonadotropic hypogonadism; premature ovarian insufficiency (POI)
(This special issue belongs to the Section Physiology and Pathology)
Vascular Disease: Etiologic, Diagnostic, Prognostic and Therapeutic Research—2nd Edition submission deadline 21 Feb 2025 | 12 articles | Viewed by 13847 | Submission Open
Keywords: vascular diseases; etiology; diagnosis; prognosis; therapy
(This special issue belongs to the Section Medical Research)
Effects of Physical Training on Youth Athletes' Physical Performance, Health and Well-Being
edited by , and Oliver Gonzalo-Skok
submission deadline 25 Feb 2025 | 6 articles | Viewed by 7882 | Submission Open
Keywords: biological maturation; strength; endurance; speed; sleep; psychosocial; physical activity; conditioning; long-term athlete development; body composition
(This special issue belongs to the Section Physiology and Pathology)
Therapeutic Effects of Natural Products on Human Diseases: 2nd Edition
edited by
submission deadline 25 Feb 2025 | 5 articles | Viewed by 6575 | Submission Open
Keywords: natural products; natural extracts; cancer; neurodegenerative diseases; immunological disorders; metabolic diseases; oriental medicine; microorganisms; algae; functional foods
(This special issue belongs to the Section Pharmaceutical Science)
Structural Biology of Pathogens and Drug Development
edited by
submission deadline 25 Feb 2025 | Viewed by 307 | Submission Open
Keywords: antiviral and antibacterial medications; emerging infectious diseases; drug-resistant pathogens; structural biology; drug discovery and design; medicinal chemistry; drug screening
(This special issue belongs to the Section Microbiology)
Pathophysiology, Diagnosis and Treatment of Immune Disease
edited by and Lucia Vietri
submission deadline 26 Feb 2025 | 3 articles | Viewed by 7716 | Submission Open
Keywords: immune disease treatment; autoimmunity; biomarkers; treatment; immunology
(This special issue belongs to the Section Physiology and Pathology)
Carbon and Nitrogen Cycles in Terrestrial Ecosystems
edited by
submission deadline 26 Feb 2025 | 2 articles | Viewed by 1900 | Submission Open
Keywords: process-based modeling and machine learning; field experiments and meta-analysis; terrestrial carbon and nitrogen cycles; role of living organisms in biogeochemical cycles
(This special issue belongs to the Section Diversity and Ecology)
Pathophysiology, Diagnosis, and Treatments of Intestinal Diseases
edited by Amosy Ephreim M’Koma
submission deadline 26 Feb 2025 | 1 articles | Viewed by 676 | Submission Open
Keywords: gastrointestinal disease/disorders; pathophysiology; diagnostics and treatment
(This special issue belongs to the Section Physiology and Pathology)
Optogenetics and Light-Induced Processes in Synthetic Biology
edited by
submission deadline 26 Feb 2025 | Viewed by 508 | Submission Open
(This special issue belongs to the Section Synthetic Biology and Systems Biology)
Helicobacter pylori
edited by and
submission deadline 28 Feb 2025 | 8 articles | Viewed by 36058 | Submission Open
Keywords: H. Pylori; cancers; antioxidative process; diagnostic methods
(This special issue belongs to the Section Microbiology)
Effects of Environmental Factors on Challenges of Plant Breeding submission deadline 28 Feb 2025 | 8 articles | Viewed by 13708 | Submission Open
Keywords: plant breeding; winter hardiness; sowing time; adaptation to cold/frost; physiology of cold/frost tolerance; snow cover
(This special issue belongs to the Section Plant Science)
Hemophilia
edited by
submission deadline 28 Feb 2025 | 9 articles | Viewed by 11600 | Submission Open
Keywords: hemophilia A-B; bleeding disorders; coagulation disorders; clotting factors; hemostasis; inherited bleeding disorders; hemorrhage; replacement therapy; gene therapy for hemophilia; hemophilia treatment centers; hemarthrosis; prophylactic treatment; joint bleeds; hemophilia genetics; hemophilia carriers
(This special issue belongs to the Section Medical Research)
Alzheimer’s Disease: Recent Developments in Pathogenesis, Diagnosis, and Therapy submission deadline 28 Feb 2025 | 5 articles | Viewed by 6557 | Submission Open
Keywords: Alzheimer’ s disease; biomarkers; epigenetics; genetics; genomics; immune mediators; neurodegeneration; neuroinflammation; proteomics; risk factors; therapy; transcriptomics
(This special issue belongs to the Section Physiology and Pathology)
Understanding Comorbidities in Gynecologic Diseases: A Holistic Approach to Women’s Health submission deadline 28 Feb 2025 | 3 articles | Viewed by 5596 | Submission Open
Keywords: women’ s health; women’ s disease; systemic diseases; comorbities; systemic approach; multi-organ
(This special issue belongs to the Section Reproductive and Developmental Biology)
Noninvasive Skin Imaging: The Present and the Future in General Dermatology
edited by and
submission deadline 28 Feb 2025 | 4 articles | Viewed by 5127 | Submission Open
Keywords: skin imaging; dermatoscopy; dermatology imaging; dermatosurgery; clinical dermatology
(This special issue belongs to the Section Medical Research)
Physical Activity in People with Cognitive Impairment submission deadline 28 Feb 2025 | 3 articles | Viewed by 4333 | Submission Open
Keywords: cognition; mild cognitive impairment; Alzheimer’ s disease; dementia; physical activity; sport; athletes with disabilities; para-athletes
(This special issue belongs to the Section Physiology and Pathology)
Management of Ischemia and Heart Failure—2nd Edition
edited by
submission deadline 28 Feb 2025 | 3 articles | Viewed by 3411 | Submission Open
Keywords: cardiac ischemia; heart failure; therapy; medical innovation; emerging technologies; care strategies; prognosis; treatment efficacy; clinical protocols; personalized therapies
(This special issue belongs to the Section Medical Research)
Clinical Research in Male Reproduction
edited by Andrea Crafa, and Richard Quinton
submission deadline 28 Feb 2025 | 2 articles | Viewed by 3409 | Submission Open
Keywords: male infertility; male fertility; male sub-fertility; idiopathic male infertility; male reproduction
(This special issue belongs to the Section Medical Research)
Fertility Preservation in Female and Male Benign and Malignant Conditions: 2nd Edition
edited by Arianna D’Angelo, Suman Dadhich and Ali Thwaini
submission deadline 28 Feb 2025 | 2 articles | Viewed by 3111 | Submission Open
Keywords: oncofertility; fertility preservation; cancer; oncology; fertility; egg freezing; embryo freezing; sperm freezing; freezing; IVF; premature ovarian failure; premature ovarian insufficiency; testicular failure; ovarian tissue freezing; PESA; TESE
(This special issue belongs to the Section Reproductive and Developmental Biology)
Latest Advances in Dermatology: From Molecular Insights into Clinical Applications
edited by and Alfonso Perez-Gonzalez
submission deadline 28 Feb 2025 | 2 articles | Viewed by 2451 | Submission Open
Keywords: dermatology; personalized medicine; molecular diagnostic techniques; targeted therapies; skin cancer; inflammatory skin diseases
(This special issue belongs to the Section Medical Research)
Unlocking New Biochemical Pathways: A Bridge for Drug Development in Human and Animal Diseases submission deadline 28 Feb 2025 | 1 articles | Viewed by 2170 | Submission Open
Keywords: drug discovery; omics sciences; veterinary sciences; oxidative stress; bioactive compounds; inflammation; cancer; neurodegeneration; cell death
(This special issue belongs to the Section Pharmaceutical Science)
Bone Remodeling
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1966 | Submission Open
Keywords: bone remodeling; osteoblast; osteoclast; osteocyte; osteoporosis
(This special issue belongs to the Section Cell Biology and Tissue Engineering)
Cardiac Arrhythmias: Physiological Mechanisms, Clinical Insights, and Epidemiological Research
edited by Thomas A. Agbaedeng
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1375 | Submission Open
Keywords: cardiac arrhythmias; atrial fibrillation; sudden cardiac death; ventricular arrhythmias; electrophysiological remodelling; structural remodelling; omics; risk factors; (epi)genetics; GWAS; PheWas; polygenic risk; machine learning models; natural language models
(This special issue belongs to the Section Medical Research)
Reconstruction of Bone Defects submission deadline 28 Feb 2025 | 1 articles | Viewed by 1301 | Submission Open
Keywords: bone and fracture biomechanics; bone healing; critical size bone defects; fracture non-union; inflammation; joint arthroplasty and fracture osteosynthesis; implant designs; materials proprieties; patient selection; primary and revision settings
(This special issue belongs to the Section Medical Research)
New Insights into Parkinson’s Disease: From Molecular Basis to Therapy submission deadline 28 Feb 2025 | 1 articles | Viewed by 1093 | Submission Open
Keywords: Parkinson’ s disease; neurodegeneration; genes; GWAs; polygenic risk score; therapy; precision medicine; pathways; pharmacogenetics; surgicogenomics
(This special issue belongs to the Section Medical Research)
Multi-Omics for Diagnosing Diseases: Bioinformatics Approaches and Integrative Data Analyses submission deadline 28 Feb 2025 | 1 articles | Viewed by 981 | Submission Open
Keywords: bioinformatics; computer hardware; software; and methods; first-/second-/third-generation sequencing; clinical genomics; mendelian diseases; whole-exome sequencing; evolutionary and comparative genomics; whole-genome sequencing; multi-omics; microbiome diseases
(This special issue belongs to the Section Genetics and Genomics)
Effects of Exercise on Susceptibility to Environmental and Disease Stressors
edited by Suzanne M. Schneider
submission deadline 28 Feb 2025 | 1 articles | Viewed by 805 | Submission Open
Keywords: aerobic exercise; physical activity; steps per day; cytokines; exerkines; hepatokines; myokines; adipokines; gut– brain axis; immune function; obesity; diabetes; cardiovascular disease; hypertension; osteoporosis; tumor growth; cognitive function; dementia; depression; sleep disorders; hyperthermia; asthma
(This special issue belongs to the Section Physiology and Pathology)
Human-Specific RNA Metabolism: Mechanisms, Dysregulation, and Disease Implications
edited by Xiangbo Ruan
submission deadline 28 Feb 2025 | Viewed by 356 | Submission Open
Keywords: human-specific RNA metabolism; mechanisms; dysregulation; disease implications
(This special issue belongs to the Section Physiology and Pathology)
Urinary Microbiome and Genitourinary System Disorders: 2nd Edition submission deadline 28 Feb 2025 | Viewed by 316 | Submission Open
Keywords: microbiome; microbiota; bacteria; 16s-RNA sequencing; bladder; urinary tract infection; urgency; incontinence; lower urinary tract symptoms (LUTS)
(This special issue belongs to the Section Microbiology)
Updates in Genetic Susceptibility to Cancers
edited by Chia-Wen Tsai
submission deadline 28 Feb 2025 | Viewed by 249 | Submission Open
Keywords: cancer genomics; genome-wide association study (GWAS); single nucleotide polymorphism (SNP); genotype-phenotype correlation; prognosis; diagnosis
(This special issue belongs to the Section Medical Research)
Epidemiology of Cancer
edited by Francesco Addabbo
submission deadline 28 Feb 2025 | Viewed by 228 | Submission Open
Keywords: cancer epidemiology; medical statistics; cancer risk factors; cancer health disparities; environmental impact; behavioural risk factors; biomarkers and systems biology; public health intervention research
(This special issue belongs to the Section Medical Research)
Laparoscopy and Treatment. An All-Encompassing Solution for Surgeons
edited by Niculae Iordache and Claudiu-Octavian Ungureanu
submission deadline 5 Mar 2025 | Viewed by 250 | Submission Open
Keywords: oncological; staging laparoscopy; tool; radical surgery; diagnostic
(This special issue belongs to the Section Medical Research)
Interdisciplinarity in Cardiovascular Pathology submission deadline 10 Mar 2025 | 1 articles | Viewed by 1493 | Submission Open
Keywords: cardiovascular disease; atherosclerosis; cardio-reno-metabolic syndrome; diabetes; obesity; obstructive pulmonary disease; sleep apnea syndrome; low-grade inflammation
(This special issue belongs to the Section Physiology and Pathology)
Etiology, Prediction and Prognosis of Ischemic Stroke
edited by , and Jiang Li
submission deadline 11 Mar 2025 | 2 articles | Viewed by 3761 | Submission Open
Keywords: ischemic stroke; recurrent stroke; etiology; machine learning; artificial intelligence; subtyping; prediction; prognosis; genetic risk factors; lifestyle factors; environmental factors; biomarkers; cerebrovascular diseases; prevention; treatment strategies
(This special issue belongs to the Section Physiology and Pathology)
Dermatology: Inflammatory Disorders and Future Perspectives
edited by
submission deadline 14 Mar 2025 | 5 articles | Viewed by 14056 | Submission Open
Keywords: psoriasis; atopic dermatitis; acne; rosacea; COVID-19; inflammatory skin diseases
(This special issue belongs to the Section Physiology and Pathology)
Soil–Plant–Microbe Interactions: The Role of Biostimulants and Agro-Environmental Implications
edited by Regina Gabilondo and
submission deadline 15 Mar 2025 | 3 articles | Viewed by 2511 | Submission Open
Keywords: soil– plant– microbe system; biostimulants; rhizosphere; fertilizers; availability of mineral nutrients; microfaunal grazing; protozoa; nematode; mycorrhizae; microbial loop
(This special issue belongs to the Section Plant Science)
Biomarkers and Prognostic Markers in Cardiovascular Diseases
edited by and Serge Sicouri
submission deadline 20 Mar 2025 | 2 articles | Viewed by 2818 | Submission Open
Keywords: biomarkers; cardiovascular disease; prognostic markers; prognostic tools; cardiac disease; aortic disease
(This special issue belongs to the Section Medical Research)
Management of Patients with Diabetes
edited by Paola Simeone
submission deadline 20 Mar 2025 | 2 articles | Viewed by 1787 | Submission Open
Keywords: prevention; diagnosis and therapies; type 2 diabetes (T2D); type 1 diabetes (T1D); diabetes mellitus; gestational diabetes mellitus (GDM)
(This special issue belongs to the Section Medical Research)
Mammalian Gametogenesis, Fertilization and Early Embryogenesis: 2nd Edition
edited by
submission deadline 20 Mar 2025 | 1 articles | Viewed by 1547 | Submission Open
Keywords: mammalian reproduction; mammalian gametogenesis; mammalian fertilization; zygote; embryogenesis; spermatogenesis; oogenesis; sperm– egg interaction; zygotic activation
(This special issue belongs to the Section Animal Science)
Environmental Exposure and Human Health: Morphological, Physiological and Clinical Consequences
edited by
submission deadline 21 Mar 2025 | 2 articles | Viewed by 2531 | Submission Open
Keywords: environmental risk; human health; morphological studies; physiological studies; molecular aspects; clinical implications; biomarkers; advanced imaging techniques; risk factors; mechanistic studies
(This special issue belongs to the Section Physiology and Pathology)
New Insights Into Leishmaniasis and Chagas Disease: Focus on Diagnosis and Genetic Characterization of Parasites: 2nd Edition
edited by and Cristina Ballart
submission deadline 21 Mar 2025 | 1 articles | Viewed by 1692 | Submission Open
Keywords: leishmania; leishmaniasis; chagas disease; American trypanosomiasis; Trypanosoma cruzi; diagnostics; genetic diversity; characterization; neglected tropical disease
(This special issue belongs to the Section Epidemiology)
Human Health Before, During, and After COVID-19
edited by Alessia Verduri
submission deadline 25 Mar 2025 | 18 articles | Viewed by 27727 | Submission Open
Keywords: COVID-19; telemedicine; pandemic-related anxiety; pandemic-related depression; long COVID; unvaccinated people; new SARS-CoV-2 variants
(This special issue belongs to the Section Epidemiology)
Diet and Vascular Disease submission deadline 25 Mar 2025 | 5 articles | Viewed by 7567 | Submission Open
Keywords: cardiovascular disease; cardiovascular risk; diet; dyslipidaemias; heart failure; human; hypertension; sodium; salt
(This special issue belongs to the Section Epidemiology)
Movement Analysis and Electrophysiology in Neurological Pathologies
edited by , Francesco Piccione and
submission deadline 25 Mar 2025 | 1 articles | Viewed by 1919 | Submission Open
Keywords: movement analysis; neurological disorders; electrophysiology
(This special issue belongs to the Section Physiology and Pathology)
Advances in Medical Imaging of Animal Models for Human Diseases
edited by and Tsai-Hsien Hung
submission deadline 25 Mar 2025 | Viewed by 180 | Submission Open
Keywords: medical imaging; animal models; preclinical research; human disease; oncology
(This special issue belongs to the Section Medical Research)
Musculoskeletal Medicine in Rheumatic Diseases
edited by and Emilio Filippucci
submission deadline 26 Mar 2025 | 3 articles | Viewed by 3485 | Submission Open
Keywords: rheumatic disease; rheumatoid arthritis; spondylarthritis; microcrystal arthritis; musculoskeletal ultrasonography; biologic treatment; disease-modifying antirheumatic drugs; imagining techniques
(This special issue belongs to the Section Medical Research)
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