Current Trends in Obstructive Sleep Apnea

Dear Colleagues,

This Special Issue focuses on Obstructive Sleep Apnea (OSA), a prevalent chronic disorder characterized by repetitive apneas and hypopneas during sleep. This disorder is associated with increased morbidity and mortality and is considered a potential etiological factor for cardiometabolic diseases such as hypertension, diabetes mellitus, stroke, insulin resistance, and atrial fibrillation. Diagnosing OSA is complex, requiring overnight sleep monitoring through polysomnography (PSG). However, PSG alone may not fully demonstrate individual susceptibility to systemic effects. Thus, the inclusion of biomarkers and vascular parameters can improve prognosis prediction and treatment response. Serum and salivary biomarkers offer promising tools for monitoring ongoing disease severity.

Various OSA treatment options, including continuous positive airway pressure (CPAP), mandibular advancement devices, upper airway (UA) surgery, and hypoglossal nerve stimulation, mainly focus on improving the impaired UA anatomy. While CPAP remains the "gold standard," its compliance rate is low, and knowledge gaps exist regarding targeted OSA therapy. Identifying clinical phenotypes and predictive factors is vital to enable personalized treatment for this complex condition.

This Special Issue aims to highlight recent advances and new perspectives in OSA diagnosis, personalized treatment strategies, and patient follow-up, enhancing our understanding of OSA and ultimately improving patient outcomes and quality of life. Authors are encouraged to contribute research on clinical phenotypes, predictive factors, and innovative treatments, striving to improve the management and outcomes of patients with OSA.

Prof. Dr. Kimberly A. Hardin
Guest Editor

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