Spinal Neuromodulation: From Basic and Translational Research to Clinical Practice
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: 25 July 2025 | Viewed by 1557
Special Issue Editor
2. Department of Neurological Surgery, University of Louisville, Louisville, KY 40202, USA
3. Department of Physiology, University of Louisville, Louisville, KY 40202, USA
Interests: spinal neuromodulation; respiratory-cardiovascular rehabilitation; locomotor rehabilitation
Special Issue Information
Dear Colleagues,
Spinal neuromodulation represents a rapidly evolving field that bridges basic neuroscience, translational research, and clinical practice. With advancements in understanding spinal cord physiology and the development of innovative technologies, neuromodulation has emerged as a promising approach for managing various neurological disorders, including chronic pain, spasticity, and motor impairments following spinal cord injury. However, significant gaps remain in elucidating the underlying mechanisms of neuromodulation, optimizing intervention protocols, and translating laboratory findings into effective clinical applications.
This Special Issue of Life aims to bring together groundbreaking research and comprehensive reviews that explore the full spectrum of spinal neuromodulation, from fundamental studies of spinal cord circuits to the latest clinical trials. We welcome submissions addressing the following topics:
- Mechanisms of action in spinal neuromodulation, including neural circuit dynamics and plasticity;
- Advances in neuromodulation technologies, including closed-loop systems, electrode design, and biofeedback integration;
- Preclinical and translational research that bridges the gap between basic neuroscience and clinical applications;
- Innovations in clinical applications of spinal neuromodulation, including interventions for spinal cord injury, neurodegenerative diseases, and chronic pain syndromes;
- Challenges and strategies for scaling neuromodulation therapies, including patient selection, long-term efficacy, and cost-effectiveness;
- Interdisciplinary approaches that integrate neuromodulation with physical rehabilitation, pharmacological treatments, and assistive technologies.
The Special Issue seeks to foster collaboration across disciplines, promoting knowledge exchange that advances the science and application of spinal neuromodulation. By highlighting state-of-the-art research and emerging trends, we aim to provide a platform for innovative studies that will shape the future of this transformative field.
Potential contributors are encouraged to submit original research articles, systematic reviews, or perspectives that align with the theme of this Special Issue. Together, let us advance the field of spinal neuromodulation and translate scientific discoveries into impactful clinical outcomes.
Dr. Alexander V. Ovechkin
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- spinal neuromodulation
- translational neuroscience
- spinal cord injury
- neural plasticity
- multi-disciplinary rehabilitation
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