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Life
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Updates on Respiratory Pathologies
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Updates on Respiratory Pathologies

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 1246

Special Issue Editor

Prof. Dr. Mieczyslaw Pokorski

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Guest Editor
Institute of Health Sciences, Opole University, 45-040 Opole, Poland
Interests: respiratory disorders; chronic obstructive pulmonary disease; respiratory tract infection; pulmonary clinical treatment

Special Issue Information

Dear Colleagues,

The incidence of respiratory disorders continues to increase worldwide. This may be exemplified by chronic obstructive pulmonary disease, which has moved to the top five causes of mortality. Respiratory disorders constitute a heavy medical and socioeconomic burden, leading to chronic health-span handicaps and shortening of lifespan. This Special Issue focuses on current aspects of clinical and basic knowledge about respiratory pathologies and their sequelae, particularly concerning cardiovascular and brain functions. The underlying reason usually is hypoxia due to breathing insufficiency.

The articles presented here will seek to contribute to the diagnosis and therapy of a range of pulmonary disorders, underscoring the intertwined relationship between respiration and other neurobiological body systems. Prospective authors should focus on cutting-edge, evidence-based pathogenetic concepts, methodologies, and innovative treatments. The respiratory tract is one of a few that are open to direct contact with the environment and thus is vulnerable to disease-causing pathogens and sources of toxicity. It is also the first line of defense in combating health risks, which requires it to work most efficiently.

The contributions presented herein will aim at addressing the needs of professionals engaged in respiratory and related medical fields and be a source of inspiration for further advancements in pulmonary clinics.

Prof. Dr. Mieczyslaw Pokorski
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • respiratory disorders
  • chronic obstructive pulmonary disease
  • respiratory tract infection
  • pulmonary clinical treatment

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

16 pages, 896 KiB  
Article
Clinical and Paraclinical Peculiarities of SARS-CoV-2 and Influenza Infections in Children: A Comparative Study
by Maria Oana Săsăran, Carmen Viorica Muntean, Andreea Bianca Stoica, Carmen Schwesig, Anca Meda Văsieșiu, Anca Doina Pleșca and Cristina Oana Mărginean
Life 2025, 15(5), 784; https://doi.org/10.3390/life15050784 - 14 May 2025
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Abstract
Background: SARS-CoV-2 and influenza can present with similar clinical pictures in children, with symptoms and paraclinical particularities which might aid in the differentiation of the two entities and which can be suggestive of various complications. The present study aims to identify clinical and [...] Read more.
Background: SARS-CoV-2 and influenza can present with similar clinical pictures in children, with symptoms and paraclinical particularities which might aid in the differentiation of the two entities and which can be suggestive of various complications. The present study aims to identify clinical and paraclinical differences between pediatric SARS-CoV-2 and influenza infection and to assess the utility of hematological parameters for prediction of their related complications. Methods: In this study, 266 children were retrospectively enrolled, divided into two groups: 129 children diagnosed with SARS-CoV-2 infection and 137 children infected with influenza. In each case, particular symptoms were recorded, as well as hospitalization duration, pediatric intensive care unit (PICU) admission or O2 supplementation requirement. Parameters of the hemoleucogram and biochemistry parameters were also collected for comparative assessment. Results: SARS-CoV-2 infections were more commonly associated with digestive symptoms, whereas influenza infections implied longer hospital stays and higher likelihood of PICU admission necessity. Monocytes and lymphocyte/monocyte ratios (LMRs) were significantly higher in the SARS-CoV-2 group (p < 0.01, p = 0.02). Several hematological parameters, such as neutrophil/lymphocyte ratios, correlated with hospitalization duration in SARS-CoV-2 and influenza B infections (p < 0.01, p = 0.01), whereas LMR was predictive of respiratory distress (p = 0.02) in the same study groups. Conclusions: According to the study, monocyte levels and LMR can aid in the distinction of pediatric SARS-CoV-2 and influenza infections and LMR and NLR can be used particularly as predictors of complicated course of these infections. Full article
(This article belongs to the Special Issue Updates on Respiratory Pathologies)
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16 pages, 1646 KiB  
Article
Cardio-Respiratory, Functional and Antalgic Effects of the Integrated Thermal Care Protocol After Breast Cancer Surgery
by Giovanni Barassi, Stefania Spina, Francesco D’Alessandro, Loris Prosperi, Celeste Marinucci, Massimo Lombardi, Maurizio Panunzio and Andrea Santamato
Life 2025, 15(3), 374; https://doi.org/10.3390/life15030374 - 27 Feb 2025
Cited by 1 | Viewed by 715
Abstract
Background: In the cardio-respiratory rehabilitation field, thermal medicine represents an interesting complementary therapy approach. It can aid in complex medical contexts characterized by cardio-respiratory deficiency, functional limitation, and pain determined by the invasiveness of pharmacological and surgical treatments in combination with limited post-surgical [...] Read more.
Background: In the cardio-respiratory rehabilitation field, thermal medicine represents an interesting complementary therapy approach. It can aid in complex medical contexts characterized by cardio-respiratory deficiency, functional limitation, and pain determined by the invasiveness of pharmacological and surgical treatments in combination with limited post-surgical physical activity. Methods: We investigated the evolution of cardio-respiratory and functional performances following the application of the Integrated Thermal Care (ITC) protocol in 11 mastectomized/quadrantectomized women (mean age of 54 years). The ITC protocol consisted of hydroponic treatments, steam inhalations treatment, hydrokinesitherapy, and manual treatments. Patients were assessed before and after a cycle of 1 h long treatment sessions, which were performed 5 days a week for 4 weeks. The outcomes were measured through the following scales and tests: Piper Fatigue Scale (PIPER), 6-Minute Walking Test (6MWT), Five Times Sit-to-Stand (5STS), Range of Arm Motion (ROM), Disability of the Arm–Shoulder–Hand Scale (DASH), and Numeric Pain Rating Scale (NPRS). Results: We found appreciable improvements in cardio-respiratory efficiency and in pain perception exemplified by a reduction of PIPER, 5STS, DASH, and NPRS values together with an increase in 6MWT and ROM values. Conclusions: We conclude that ITC is a promising rehabilitative tool to enhance cardio-respiratory and functional performance and reduce pain after mastectomy/quadrantectomy. Full article
(This article belongs to the Special Issue Updates on Respiratory Pathologies)
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