Blood Rheology: Insights & Innovations
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: 28 July 2025 | Viewed by 1966
Special Issue Editor
Special Issue Information
Dear Colleagues,
Hemorheology is the science of the rheology of blood and its constituents under stress during blood flow in the cardiovascular system, causing it to strain and activate under physiological conditions. Erythrocytes, leukocytes, and platelets are subjected to mechanical stresses in the cardiovascular system during flow that cause their deformation and chemical activation within physiological limits and beyond these limits in pathological conditions. There are many methods for studying the rheological properties of blood and its constituents. Methods based on atomic force microscopy (AFM) have been introduced and applied to study the mechanical properties of the blood cell membrane and PLT activation. The introduction of AFM technologies into biomedical research opens up opportunities to develop fundamentally new approaches to study the mechanical properties of blood cell membranes at different stages of ontogenesis. Microfluidics has become a prominent field for the study of blood microrheology and the mechanical properties of blood cells—erythrocytes, leukocytes, and platelets. Many experimental and clinical studies are aimed at the changes in the rheological properties of blood in patients with various pathologies such as cerebrovascular disease of ischemic origins, stroke, in patients with type 2 diabetes mellitus, patients with COVID and post-COVID, during physical exercise, etc. Experimental and clinical studies have shown the influence of blood viscosity and its determinants on blood flow. On the other hand, abnormal hemorheological changes are considered risk factors in these diseases.
This Special Issue aims to showcase research articles and review articles focusing on all aspects of clinical, applied, and basic chemorheological, micromechanical, and mechanobiological research, promising new therapeutic developments and focusing research on the effects of mechanical forces on cells, tissues, and the development of biological systems and tools.
Prof. Dr. Nadia Antonova
Guest Editor
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Keywords
- hemorheology
- microfluidics
- blood viscosity
- mechanobiology
- cellular mechanics
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