Special Issues

Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Advances in Diagnosis and Personalized Treatments of Chronic Kidney Diseases submission deadline 31 Aug 2026 | 5 articles | Viewed by 8797 | Submission Open
Keywords: biomarkers for early diagnosis; genetic testing; precision medicine approaches; novel therapies; telemedicine and remote monitoring; nutritional interventions; regenerative medicine
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Advances in Prenatal Diagnosis and Maternal Fetal Medicine submission deadline 31 Aug 2026 | 3 articles | Viewed by 8085 | Submission Open
Keywords: prenatal diagnosis; maternal– fetal medicine; fetal anomalies; genetic screening; fetal imaging; non-invasive prenatal testing (NIPT); obstetric care; perinatal outcomes; diagnostic technologies; artificial intelligence
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Updates on Heart Valve Diseases: Personalized Treatment and Management
edited by Chiara Tessari
submission deadline 31 Aug 2026 | 4 articles | Viewed by 7569 | Submission Open
Keywords: heart valve disease; congenital heart valve disease; transcatheter valve implantation/replacement; surgical technique; device technology; tissue engineering; structural valve deterioration; device failure/success
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Integrating Mathematical Modeling and Data Analysis in Personalized Medical Research submission deadline 31 Aug 2026 | 4 articles | Viewed by 6629 | Submission Open
Keywords: personalized medicine; health informatics; mathematical modeling; data analysis; bioinformatics; artificial intelligence; machine learning
(This special issue belongs to the Section Omics/Informatics)
Personalized Medicine in Infectious Diseases submission deadline 31 Aug 2026 | 1 articles | Viewed by 6206 | Submission Open
Keywords: infectious diseases; genetic predisposition; post-acute infection syndromes; long-COVID; response; potential adverse events; and duration of protection of vaccines; response to therapy and development of resistance; personalized medicine; precision diagnostics; treatment strategies
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Novel Applications of Artificial Intelligence in Personalized Medicine
edited by Aikaterini Sakagianni
submission deadline 31 Aug 2026 | 3 articles | Viewed by 4738 | Submission Open
Keywords: artificial intelligence  ; personalized medicine  ; predictive modeling  ; genomics  ; proteomics  ; AI-driven diagnostics  ; patient-specific treatment  ; drug discovery  ; healthcare innovation  ; clinical applications of AI
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Medicine in the ICU—2nd Edition submission deadline 31 Aug 2026 | 2 articles | Viewed by 3387 | Submission Open
Keywords: ARDS; mechanical ventilation; respiratory mechanics; monitoring; ultrasonography; respiratory muscles; diaphragm; cardiomyopathy; arrhythmias; sepsis; blood stream infections; antimicrobial resistance; ventilator-associated pneumonia; neuromonitoring; MODS; COVID-19
(This special issue belongs to the Section Personalized Medical Care)
Personalized Medicine in Gynecological Oncology: Update and Challenge
edited by
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1074 | Submission Open
Keywords: gynecologic oncology; personalized medicine; imaging and biomarkers; fertility-sparing surgery
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
New Insights into the Diagnosis and Treatment of Gastroenterological Diseases
edited by Ebubekir Dağlılar and Harleen Chela
submission deadline 31 Aug 2026 | Viewed by 261 | Submission Open
Keywords: gastroenterology; precision medicine; multi-omics integration; pharmacogenomics; liquid biopsy; gastrointestinal biomarkers; inflammatory bowel disease (IBD); individualized treatment strategies
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Cell-Free Nucleic Acids as Precision Biomarkers for Therapeutic Decision-Making Across Diseases
edited by and Francis Barany
submission deadline 31 Aug 2026 | Viewed by 229 | Submission Open
Keywords: liquid biopsy; cell-free nucleic acids; cancer; therapeutic decision; cell-free DNA
(This special issue belongs to the Section Disease Biomarkers)
Sex- and Gender-Related Issues in the Era of Personalized Medicine, 2nd Edition
edited by , Biagio Moretti and Anna Maria Moretti
submission deadline 31 Aug 2026 | Viewed by 224 | Submission Open
Keywords: gender; sex differences; sex factors; personalized medicine; cardiovascular disease; hypertension; obesity; diabetes; psychiatry and psychology; public health and epidemiology; women’ s health; sex; osteoporosis; osteoarthritis; musculoskeletal diseases
(This special issue belongs to the Section Personalized Preventive Medicine)
Personalized Medicine Based on Pharmacoepidemiology
edited by
submission deadline 31 Aug 2026 | Viewed by 216 | Submission Open
Keywords: personalized medicine; pharmacoepidemiology; pharmacovigilance; real-world evidence (RWE); adverse drug reactions; pharmacogenomics; predictive modeling; big data in healthcare; patient stratification
(This special issue belongs to the Section Personalized Medical Care)
Pathophysiology and Personalized Therapy of Allergic Diseases
edited by Florin-Dan Popescu and
submission deadline 31 Aug 2026 | Viewed by 199 | Submission Open
Keywords: allergic diseases; pathophysiology; molecular allergology; biomarkers; precision medicine
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Medicine for Clinical Psychology submission deadline 10 Sep 2026 | 3 articles | Viewed by 3298 | Submission Open
Keywords: personalized medicine; clinical psychology; integrated care; psychosomatic medicine; patient-centered care; digital health; individualized intervention; psycho-oncology
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Assisted Reproduction: Clinical Updates and Personalized Strategies submission deadline 15 Sep 2026 | Viewed by 278 | Submission Open
Keywords: female infertility; male infertility; assisted reproduction; in vitro fertilization (IVF); personalized treatment; fertility treatment; ovarian stimulation; embryo selection; cryopreservation; reproductive genetics
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Pharmacogenetics and Synaptic Plasticity in Neurological Disorders: From Mechanisms to Therapies
edited by Hector Vargas-Perez and América Vanoye-Carlo
submission deadline 15 Sep 2026 | Viewed by 183 | Submission Open
Keywords: pharmacogenetics; precision neurotherapeutics; mitochondrial bioenergetics; epigenetic regulation; gene– drug interactions; synaptic plasticity; neuropsychiatric and neurodegenerative disorders
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Medicine in Reproductive Medicine
edited by and Carla Ettore
submission deadline 20 Sep 2026 | 1 articles | Viewed by 1720 | Submission Open
Keywords: personalized medicine; reproductive medicine; assisted reproductive technologies (ART); infertility; implantation failure; recurrent pregnancy loss; ovarian stimulation; endometrial receptivity
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Medicine in Epidemiology and Infectious Diseases
edited by Takalani Grace Tshitangano and Daniel Ter Goon
submission deadline 20 Sep 2026 | Viewed by 287 | Submission Open
Keywords: personalized medicine; infectious disease; epidemiology; precision public health; pharmacogenomics; AI in epidemiology; pathogen genomics; digital health; risk prediction models; multi-omics integration; machine learning; personalized treatment
(This special issue belongs to the Section Diagnostics in Personalized Medicine)
Clinical Child Psychology: New Advances in Personalized Treatment and Management
edited by Giulia Zucchetti
submission deadline 24 Sep 2026 | Viewed by 217 | Submission Open
Keywords: personalized therapy; clinical child psychology; chronic and neuropsychiatric conditions in children; child maltreatment and trauma; family-centered care
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Laparoscopy, Perioperative Care and Complications in Surgery for Gastrointestinal Diseases
edited by Michał Kisielewski
submission deadline 25 Sep 2026 | 3 articles | Viewed by 6575 | Submission Open
Keywords: laparoscopy; perioperative care; colorectal surgery; minimally invasive surgery; upper digestive surgery; hepatobiliary surgery; postoperative complications
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Radiation Therapy for Cancers: Current Status and Future Perspectives
edited by Roberta Carbonara and
submission deadline 25 Sep 2026 | 4 articles | Viewed by 5110 | Submission Open
Keywords: personalized radiotherapy; personalized oncology; adaptive radiotherapy; stereotactic radiotherapy; re-irradiation; immuno-radiotherapy; tumor microenvironment and radiotherapy
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Medicine in Otolaryngology: New Challenges and Future Perspectives
edited by Jerome Rene Lechien
submission deadline 25 Sep 2026 | 1 articles | Viewed by 1921 | Submission Open
Keywords: otolaryngology; oral cancer; oncology; head and neck surgery; minimally invasive; laryngology; artificial intelligence; rhinology; ENT; personalized
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Clinical Management and Personalized Treatment in Digestive Surgery submission deadline 25 Sep 2026 | Viewed by 630 | Submission Open
Keywords: digestive disease; digestive cancers; gastrointestinal surgery; stomach; pancreas; liver
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Medicine in Reproduction and Fertility
edited by Nikos K. Nikolettos
submission deadline 25 Sep 2026 | Viewed by 557 | Submission Open
Keywords: personalized medicine; fertility; assisted reproduction; reproductive health
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Artificial Intelligence in Cardiovascular Diseases: Toward Personalized Diagnosis and Treatment
edited by Diaa A. Hakim
submission deadline 25 Sep 2026 | 1 articles | Viewed by 368 | Submission Open
Keywords: artificial intelligence; machine learning; deep learning; cardiovascular diseases; personalized treatment
(This special issue belongs to the Section Diagnostics in Personalized Medicine)
Precision Medicine in Spine Surgery: Updates and Challenges
edited by Mark James Lambrechts
submission deadline 25 Sep 2026 | Viewed by 348 | Submission Open
Keywords: spine; orthopedic surgery; neurosurgery; precision; endoscopic spine; artificial disc replacement; spinal deformity; patient-specific alignment
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Psychiatry: Clinical Research and Personalized Medicine
edited by Georgios Floros
submission deadline 25 Sep 2026 | Viewed by 301 | Submission Open
Keywords: personalized therapy; clinical psychiatry; pharmacogenomics; biomarker-driven therapies; machine learning; digital phenotyping; precision psychiatry; mental health; individualized treatment; neuroimaging
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Clinical Diagnosis and Personalized Treatment in Otolaryngology
edited by
submission deadline 25 Sep 2026 | Viewed by 247 | Submission Open
Keywords: personalized medicine; precision diagnosis; otolaryngology; otorhinolaryngology; head and neck surgery; head and neck oncology; imaging and functional evaluation; artificial intelligence; audiology and vestibular testing; swallowing and voice assessment; olfactory and gustatory disorders
(This special issue belongs to the Section Diagnostics in Personalized Medicine)
Head and Neck Disease: Personalized Approaches to Screening and Diagnosis
edited by Heejin Kim
submission deadline 25 Sep 2026 | Viewed by 241 | Submission Open
Keywords: otolaryngology; head and neck; rhinosinusitis; thyroidectomy; tonsillectomy; personalized; screening; diagnosis
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Treatment and Rehabilitation for Colorectal Cancer
edited by Gabriella Teresa Capolupo
submission deadline 25 Sep 2026 | Viewed by 200 | Submission Open
Keywords: colorectal rehabilitation; ERAS; colorectal cancer; colorectal surgery; personalized treatment
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Medicine in Obstetrics and Urogynaecology: Updates and Challenges
edited by and Dimos Sioutis
submission deadline 28 Sep 2026 | Viewed by 235 | Submission Open
Keywords: gynaecology; urogynaecology; obstetrics; pelvic floor disorders; personalized diagnosis; urinary tract infections; pelvic organ prolapse; pelvic pain; urinary and bowel incontinence; complication; women's health; pessary; conseravtive management
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
New Insights into Personalized Medicine for Anesthesia and Pain
edited by and Guen Joo Choi
submission deadline 30 Sep 2026 | 6 articles | Viewed by 9372 | Submission Open
Keywords: new insights; personalized medicine; anesthesia; pain management; perioperative analgesia; airway management; perioperative nausea; interventional pain care; critical care; minimally invasive surgery/robotic surgery; mechanical ventilation; chronic pain; acute pain; lumbar/cervical/thoracic/spinal pain; musculoskeletal pain
(This special issue belongs to the Section Personalized Medical Care)
Novel Challenges and Therapeutic Options for Digestive and Liver Diseases—2nd Edition submission deadline 30 Sep 2026 | 3 articles | Viewed by 6310 | Submission Open
Keywords: digestive disease; gastrointestinal disease; pancreas; gallbladder; liver disease; therapy; management; microbiota; drugs; diagnosis
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Innovations in Airway Diseases
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 4239 | Submission Open
Keywords: airway pathophysiology; respiratory therapeutics; novel diagnostic techniques; personalized medicine; clinical trials in airway diseases; innovative treatment strategies; molecular mechanisms; biotechnological advances; environmental impacts; advanced diagnostic tools
(This special issue belongs to the Section Mechanisms of Diseases)
Recent Developments in Cancer Biomarkers for Diagnosis and Prognosis
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 2452 | Submission Open
Keywords: cancer biomarkers; diagnosis; prognosis; therapy response biomarkers; miRNA; RNA; DNA; and proteins; cell-free biomarkers; saliva; serum; and plasma; inflammation; metabolites
(This special issue belongs to the Section Disease Biomarkers)
Current Status and Future Prospects of Histopathology in Cancer Diagnosis
edited by Serena Ammendola and
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1497 | Submission Open
Keywords: histopathology; cancer diagnostics; cancer biology; prognostic markers; targeted therapy; immunohistochemistry; molecular biology; digital pathology; artificial intelligence
(This special issue belongs to the Section Mechanisms of Diseases)
Novel Challenges and Advances in Neuro-Oncology
edited by and José Pedro Lavrador
submission deadline 30 Sep 2026 | 1 articles | Viewed by 989 | Submission Open
Keywords: neuro-oncology; brain mapping; personalized surgical resections; radiotherapy; proton therapy; chemotherapy; immunotherapy; tumour-brain interaction; flourescence-guided surgery; intraoperative treatments; postoperative rehabilitation; engenieering and neuro-oncology
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Medicine in Neuropsychology
edited by Bruno Peixoto
submission deadline 30 Sep 2026 | Viewed by 375 | Submission Open
Keywords: precision neuroscience; advances in neuropsychology; neurocognitive profiling; neurorehabilitation; personalized medicine; biomarkers
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Approaches in Cardiothoracic Surgery submission deadline 30 Sep 2026 | Viewed by 261 | Submission Open
Keywords: minimal invasive cardiothoracic surgery; complex cardiothoracic procedures; redo surgery; robotic cardiothoracic surgery; AI in the treatment of cardiothoracic diseases; guidelines of the treatment of cardiothoracic diseases; education and training in cardiothoracic surgery; perioperative management; technical advancements; innovations; research
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Advancements in Neurosurgical Oncology: Bridging Neurosurgery and Cancer Neuroscience submission deadline 15 Oct 2026 | 1 articles | Viewed by 17003 | Submission Open
Keywords: neuro-oncology; cancer progression; neural mechanisms in cancer; brain tumors; neurological implications of cancer; cancer-induced neuropathy; neural stem cells and cancer; neuroinflammation in cancer; neuroimaging in oncology; cancer therapeutics and neurological safety
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Otolaryngology in Clinical Practice: The Necessity of Personalized Medicine
edited by Jerome Rene Lechien
submission deadline 15 Oct 2026 | 8 articles | Viewed by 9264 | Submission Open
Keywords: otolaryngology; otorhinolaryngology; artificial Intelligence; personalized Medicine; treatments
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Recent Advances in Bariatric Surgery
edited by and Andrea Peri
submission deadline 15 Oct 2026 | 4 articles | Viewed by 7417 | Submission Open
Keywords: bariatric surgery; morbid obesity; sleeve gastrectomy; gastric bypass; emerging procedures; early outcomes; long-term results
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Acute Myeloid Leukemia: Current Progress and Future Directions submission deadline 15 Oct 2026 | 4 articles | Viewed by 5678 | Submission Open
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Precision Care in Pediatric and Neonatal Intensive Care
edited by Tsz Yan Milly Lo, Laura Moss and
submission deadline 15 Oct 2026 | 1 articles | Viewed by 1834 | Submission Open
Keywords: pediatric intensive care; neonatal intensive care; AI in intensive care; biomarkers; omics; genetics; precision medicine; personalised medicine; ARDS; mechanical ventilation; haemodynamics; neuromonitoring; sepsis; traumatic brain injury; acquired brain injury; hypoxic ischemic encephalopathy; prematurity; post-operative surgical care; renal replacement therapy; acute kidney injury; cardiomyopathies; congential cardiac disease; multi-modal monitoring; antimicrobial resistance
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Plastic Surgery: New Perspectives and Innovative Techniques
edited by Joseph M. Escandón and
submission deadline 20 Oct 2026 | 6 articles | Viewed by 10999 | Submission Open
Keywords: plastic surgery procedures; free tissue flaps; gender-affirmation surgery; reconstructive procedures; lymphedema; breast cancer; oncologic reconstruction; body contouring; regenerative medicine; stem cell therapy; aesthetic surgery
(This special issue belongs to the Section Regenerative Medicine and Therapeutics)
Inflammatory Bowel Disease (IBD): Diagnosis and Personalized Treatment submission deadline 20 Oct 2026 | 5 articles | Viewed by 5896 | Submission Open
Keywords: inflammatory bowel disease; diagnostic tools; biomarkers; therapeutic strategies; molecular mechanisms; microbiome; genetic predispositions; environmental factors; personalized treatment
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine in Gynecology and Obstetrics submission deadline 20 Oct 2026 | 2 articles | Viewed by 3865 | Submission Open
Keywords: personalized medicine; genetic screening; risk assessment for pregnancy complications; fetal health monitoring; pharmacogenomics; hormone therapy; genetic testing for cancer risk fertility treatments; endometriosis; fibroid management; preventive care and screening
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Advances in Oral Health: Innovative and Personalized Approaches
edited by , Heleni Vastardis and
submission deadline 25 Oct 2026 | 6 articles | Viewed by 11320 | Submission Open
Keywords: artificial intelligence; machine learning; genetics; orthodontics; pediatric dentistry; preventive dentistry; periodontology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Advances in the Use of Machine Learning for Personalized Medicine
edited by
submission deadline 25 Oct 2026 | 1 articles | Viewed by 3848 | Submission Open
Keywords: LLMs in medicine; machine learning; deep learning; drug discovery; personalized medicine
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Plastic and Reconstructive Surgery: Challenges and Prospects
edited by Johnny Ionut Efanov and Alain Michel Danino
submission deadline 25 Oct 2026 | 2 articles | Viewed by 1762 | Submission Open
Keywords: reconstructive surgery; plastic surgery; flaps reconstruction; breast reconstruction; 3D printing; personalized surgery; biomaterials; imaging-assisted surgery; robotics
(This special issue belongs to the Section Regenerative Medicine and Therapeutics)
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