Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
6.0
Journals
JPM
Special Issues
Personalized Radiation Therapy for Cancers: Current Status and Future Perspectives
share announcement

Personalized Radiation Therapy for Cancers: Current Status and Future Perspectives

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Methodology, Drug and Device Discovery".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 969

Special Issue Editors

Dr. Roberta Carbonara

E-Mail Website
Guest Editor
Radiation Oncology Department, General Regional Hospital F. Miulli, Strada Provinciale 127, Acquaviva delle Fonti, 70021 Bari, Italy
Interests: radiation oncology; personalized oncology; radiomics; stereotactic radiotherapy; breast cancer; prostate cancer; head and neck cancer
Dr. Alba Fiorentino

E-Mail Website
Guest Editor
1. Department of Radiation Oncology, Miulli General Regional Hospital, 70021 Bari, Italy
2. Department of Medicine and Surgery, LUM University, 70010 Bari, Italy
Interests: radiation oncology; personalized oncology; stereotactic radiotherapy; reirradiation; neuro-oncology; breast cancer; prostate cancer
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In the era of personalized oncology, a significant improvement in patient outcomes has been achieved thanks to a favorable combination of modern knowledge on cancer (i.e., cancer-related genomic and immunological profiles, tumor microenvironment of the primary and metastatic sites, clinicopathological and imaging features predictive of clinical outcomes), technological advances in the diagnostic and radiation oncology fields, as well as recent insights in radiobiology.

Nowadays, a multidisciplinary, integrated approach to cancer patients leads to selecting treatments according to disease-specific proliferating pathways and obtaining synergistic effects between radiotherapy and immunotherapy or targeted therapies.

Furthermore, modern radiation oncology allows higher conformity treatments, adaptive approaches, and salvage/ablative re-irradiation of recurrences, with a significant impact on disease control and patients' quality of life.

This Special Issue will address the current advances and future perspectives in the field of personalized radiation oncology, underscoring the relevance of multidisciplinary evaluations to improve tailored treatments and enhance cancer patients’ outcomes.

Dr. Roberta Carbonara
Dr. Alba Fiorentino
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • personalized radiotherapy
  • personalized oncology
  • adaptive radiotherapy
  • stereotactic radiotherapy
  • re-irradiation
  • immuno-radiotherapy
  • tumor microenvironment and radiotherapy

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Review

14 pages, 1002 KiB  
Review
3D-Printed Devices in Interventional Radiotherapy (Brachytherapy) Applications: A Literature Review
by Enrico Rosa, Sofia Raponi, Bruno Fionda, Maria Vaccaro, Valentina Lancellotta, Antonio Napolitano, Gabriele Ciasca, Leonardo Bannoni, Patrizia Cornacchione, Luca Tagliaferri, Marco De Spirito and Elisa Placidi
J. Pers. Med. 2025, 15(6), 262; https://doi.org/10.3390/jpm15060262 - 19 Jun 2025
Viewed by 519
Abstract
Introduction: Interventional radiotherapy (brachytherapy, IRT, BT) has evolved with technological advancements, improving dose precision while minimizing exposure to healthy tissues. The integration of 3D-printing technology in IRT has enabled the development of patient-specific devices, optimizing treatment personalization and dosimetric accuracy. Methods: [...] Read more.
Introduction: Interventional radiotherapy (brachytherapy, IRT, BT) has evolved with technological advancements, improving dose precision while minimizing exposure to healthy tissues. The integration of 3D-printing technology in IRT has enabled the development of patient-specific devices, optimizing treatment personalization and dosimetric accuracy. Methods: A systematic literature search was conducted in PubMed, Scopus, and Google Scholar to identify studies published between 2020 and 2024 on 3D-printing applications in IRT. The selection process resulted in 74 peer-reviewed articles categorized by radioactive source, brachytherapy technique, endpoint of the 3D-printed product, and study type. Results: The analysis highlights the growing implementation of 3D-printed devices in brachytherapy, particularly in gynecological, prostate, and skin cancers. Most studies focus on technique, including intracavitary, interstitial, and contact applications, with custom applicators and templates emerging as predominant endpoints. The majority of studies involved in vivo clinical applications, followed by in silico computational modeling and in vitro experiments. Conclusions: The upward trend in scientific publications underscores the growing attention on 3D printing for enhancing personalized brachytherapy. The increasing use of 3D-printed templates and applicators highlights their role in optimizing dose delivery and expanding personalized treatment strategies. The current research trend is shifting toward real-world data and in vivo studies to assess clinical applications, ensuring these innovations translate effectively into routine practice. The integration of 3D printing represents a major advancement in radiation oncology, with the potential to enhance treatment efficacy and patient outcomes. Future research should focus on standardizing manufacturing processes and expanding clinical validation to facilitate broader adoption. Full article
(This article belongs to the Special Issue Personalized Radiation Therapy for Cancers: Current Status and Future Perspectives)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop