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Special Issues

Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Personalized Medicine in Reproduction and Fertility
edited by Nikos K. Nikolettos
submission deadline 25 Sep 2026 | Viewed by 390 | Submission Open
Keywords: personalized medicine; fertility; assisted reproduction; reproductive health
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Precision Medicine in Spine Surgery: Updates and Challenges
edited by Mark James Lambrechts
submission deadline 25 Sep 2026 | Viewed by 210 | Submission Open
Keywords: spine; orthopedic surgery; neurosurgery; precision; endoscopic spine; artificial disc replacement; spinal deformity; patient-specific alignment
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Head and Neck Disease: Personalized Approaches to Screening and Diagnosis
edited by Heejin Kim
submission deadline 25 Sep 2026 | Viewed by 147 | Submission Open
Keywords: otolaryngology; head and neck; rhinosinusitis; thyroidectomy; tonsillectomy; personalized; screening; diagnosis
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Clinical Diagnosis and Personalized Treatment in Otolaryngology
edited by
submission deadline 25 Sep 2026 | Viewed by 134 | Submission Open
Keywords: personalized medicine; precision diagnosis; otolaryngology; otorhinolaryngology; head and neck surgery; head and neck oncology; imaging and functional evaluation; artificial intelligence; audiology and vestibular testing; swallowing and voice assessment; olfactory and gustatory disorders
(This special issue belongs to the Section Diagnostics in Personalized Medicine)
Psychiatry: Clinical Research and Personalized Medicine
edited by Georgios Floros
submission deadline 25 Sep 2026 | Viewed by 126 | Submission Open
Keywords: personalized therapy; clinical psychiatry; pharmacogenomics; biomarker-driven therapies; machine learning; digital phenotyping; precision psychiatry; mental health; individualized treatment; neuroimaging
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Treatment and Rehabilitation for Colorectal Cancer
edited by Gabriella Teresa Capolupo
submission deadline 25 Sep 2026 | Viewed by 77 | Submission Open
Keywords: colorectal rehabilitation; ERAS; colorectal cancer; colorectal surgery; personalized treatment
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Artificial Intelligence in Cardiovascular Diseases: Toward Personalized Diagnosis and Treatment
edited by Diaa A. Hakim
submission deadline 25 Sep 2026 | Viewed by 68 | Submission Open
Keywords: artificial intelligence; machine learning; deep learning; cardiovascular diseases; personalized treatment
(This special issue belongs to the Section Diagnostics in Personalized Medicine)
Personalized Medicine in Obstetrics and Urogynaecology: Updates and Challenges
edited by and Dimos Sioutis
submission deadline 28 Sep 2026 | Viewed by 102 | Submission Open
Keywords: gynaecology; urogynaecology; obstetrics; pelvic floor disorders; personalized diagnosis; urinary tract infections; pelvic organ prolapse; pelvic pain; urinary and bowel incontinence; complication; women's health; pessary; conseravtive management
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
New Insights into Personalized Medicine for Anesthesia and Pain
edited by and Guen Joo Choi
submission deadline 30 Sep 2026 | 3 articles | Viewed by 5366 | Submission Open
Keywords: new insights; personalized medicine; anesthesia; pain management; perioperative analgesia; airway management; perioperative nausea; interventional pain care; critical care; minimally invasive surgery/robotic surgery; mechanical ventilation; chronic pain; acute pain; lumbar/cervical/thoracic/spinal pain; musculoskeletal pain
(This special issue belongs to the Section Personalized Medical Care)
Novel Challenges and Therapeutic Options for Digestive and Liver Diseases—2nd Edition submission deadline 30 Sep 2026 | 2 articles | Viewed by 3819 | Submission Open
Keywords: digestive disease; gastrointestinal disease; pancreas; gallbladder; liver disease; therapy; management; microbiota; drugs; diagnosis
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Innovations in Airway Diseases
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 3757 | Submission Open
Keywords: airway pathophysiology; respiratory therapeutics; novel diagnostic techniques; personalized medicine; clinical trials in airway diseases; innovative treatment strategies; molecular mechanisms; biotechnological advances; environmental impacts; advanced diagnostic tools
(This special issue belongs to the Section Mechanisms of Diseases)
Recent Developments in Cancer Biomarkers for Diagnosis and Prognosis
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1356 | Submission Open
Keywords: cancer biomarkers; diagnosis; prognosis; therapy response biomarkers; miRNA; RNA; DNA; and proteins; cell-free biomarkers; saliva; serum; and plasma; inflammation; metabolites
(This special issue belongs to the Section Disease Biomarkers)
Current Status and Future Prospects of Histopathology in Cancer Diagnosis
edited by Serena Ammendola and
submission deadline 30 Sep 2026 | Viewed by 610 | Submission Open
Keywords: histopathology; cancer diagnostics; cancer biology; prognostic markers; targeted therapy; immunohistochemistry; molecular biology; digital pathology; artificial intelligence
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Medicine in Neuropsychology
edited by Bruno Peixoto
submission deadline 30 Sep 2026 | Viewed by 188 | Submission Open
Keywords: precision neuroscience; advances in neuropsychology; neurocognitive profiling; neurorehabilitation; personalized medicine; biomarkers
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Approaches in Cardiothoracic Surgery submission deadline 30 Sep 2026 | Viewed by 69 | Submission Open
Keywords: minimal invasive cardiothoracic surgery; complex cardiothoracic procedures; redo surgery; robotic cardiothoracic surgery; AI in the treatment of cardiothoracic diseases; guidelines of the treatment of cardiothoracic diseases; education and training in cardiothoracic surgery; perioperative management; technical advancements; innovations; research
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Novel Challenges and Advances in Neuro-Oncology
edited by and José Pedro Lavrador
submission deadline 30 Sep 2026 | Viewed by 63 | Submission Open
Keywords: neuro-oncology; brain mapping; personalized surgical resections; radiotherapy; proton therapy; chemotherapy; immunotherapy; tumour-brain interaction; flourescence-guided surgery; intraoperative treatments; postoperative rehabilitation; engenieering and neuro-oncology
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Advancements in Neurosurgical Oncology: Bridging Neurosurgery and Cancer Neuroscience submission deadline 15 Oct 2026 | 1 articles | Viewed by 14705 | Submission Open
Keywords: neuro-oncology; cancer progression; neural mechanisms in cancer; brain tumors; neurological implications of cancer; cancer-induced neuropathy; neural stem cells and cancer; neuroinflammation in cancer; neuroimaging in oncology; cancer therapeutics and neurological safety
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Recent Advances in Bariatric Surgery
edited by and Andrea Peri
submission deadline 15 Oct 2026 | 4 articles | Viewed by 5743 | Submission Open
Keywords: bariatric surgery; morbid obesity; sleeve gastrectomy; gastric bypass; emerging procedures; early outcomes; long-term results
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Otolaryngology in Clinical Practice: The Necessity of Personalized Medicine
edited by Jerome Rene Lechien
submission deadline 15 Oct 2026 | 5 articles | Viewed by 3737 | Submission Open
Keywords: otolaryngology; otorhinolaryngology; artificial Intelligence; personalized Medicine; treatments
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Acute Myeloid Leukemia: Current Progress and Future Directions submission deadline 15 Oct 2026 | 1 articles | Viewed by 2920 | Submission Open
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Precision Care in Pediatric and Neonatal Intensive Care
edited by Tsz Yan Milly Lo, Laura Moss and
submission deadline 15 Oct 2026 | 1 articles | Viewed by 177 | Submission Open
Keywords: pediatric intensive care; neonatal intensive care; AI in intensive care; biomarkers; omics; genetics; precision medicine; personalised medicine; ARDS; mechanical ventilation; haemodynamics; neuromonitoring; sepsis; traumatic brain injury; acquired brain injury; hypoxic ischemic encephalopathy; prematurity; post-operative surgical care; renal replacement therapy; acute kidney injury; cardiomyopathies; congential cardiac disease; multi-modal monitoring; antimicrobial resistance
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Plastic Surgery: New Perspectives and Innovative Techniques
edited by Joseph M. Escandón and
submission deadline 20 Oct 2026 | 6 articles | Viewed by 7295 | Submission Open
Keywords: plastic surgery procedures; free tissue flaps; gender-affirmation surgery; reconstructive procedures; lymphedema; breast cancer; oncologic reconstruction; body contouring; regenerative medicine; stem cell therapy; aesthetic surgery
(This special issue belongs to the Section Regenerative Medicine and Therapeutics)
Personalized Medicine in Gynecology and Obstetrics submission deadline 20 Oct 2026 | 1 articles | Viewed by 2648 | Submission Open
Keywords: personalized medicine; genetic screening; risk assessment for pregnancy complications; fetal health monitoring; pharmacogenomics; hormone therapy; genetic testing for cancer risk fertility treatments; endometriosis; fibroid management; preventive care and screening
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Inflammatory Bowel Disease (IBD): Diagnosis and Personalized Treatment
edited by Abigail Raffner (formerly Basson)
submission deadline 20 Oct 2026 | Viewed by 376 | Submission Open
Keywords: inflammatory bowel disease; diagnostic tools; biomarkers; therapeutic strategies; molecular mechanisms; microbiome; genetic predispositions; environmental factors; personalized treatment
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Advances in Oral Health: Innovative and Personalized Approaches
edited by , Heleni Vastardis and
submission deadline 25 Oct 2026 | 3 articles | Viewed by 6217 | Submission Open
Keywords: artificial intelligence; machine learning; genetics; orthodontics; pediatric dentistry; preventive dentistry; periodontology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Advances in the Use of Machine Learning for Personalized Medicine
edited by
submission deadline 25 Oct 2026 | 1 articles | Viewed by 2935 | Submission Open
Keywords: LLMs in medicine; machine learning; deep learning; drug discovery; personalized medicine
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Plastic and Reconstructive Surgery: Challenges and Prospects
edited by Johnny Ionut Efanov and Alain Michel Danino
submission deadline 25 Oct 2026 | 1 articles | Viewed by 749 | Submission Open
Keywords: reconstructive surgery; plastic surgery; flaps reconstruction; breast reconstruction; 3D printing; personalized surgery; biomaterials; imaging-assisted surgery; robotics
(This special issue belongs to the Section Regenerative Medicine and Therapeutics)
Interventional Cardiology and Personalized Medicine
edited by Arnoud W. J. van 't Hof, Pieter A. Vriesendorp and Árpád Lux
submission deadline 25 Oct 2026 | Viewed by 508 | Submission Open
Keywords: coronary artery disease; diffuse CAD; aortic valve stenosis; TAVI; mitraclip; mitral regurgitation; acute coronary syndromes
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Medicine and Management of Gynecologic Cancer
edited by Hooman Soleymani majd and
submission deadline 25 Oct 2026 | Viewed by 273 | Submission Open
Keywords: proteomic; genomic; biomarkers; precision medicine; molecular profiling; immunotherapy; gynecologic cancer
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Bioinformatics and Data Analysis for Common Diseases: Advances in Precision Medicine
edited by
submission deadline 25 Oct 2026 | Viewed by 64 | Submission Open
Keywords: bioinformatics; statistical genetics; causal inference; meta-analysis; Mendelian randomization; machine learning
(This special issue belongs to the Section Omics/Informatics)
Precision Medicine in Myocardial Infarction: Diagnosis, Prevention, and Treatment
edited by
submission deadline 25 Oct 2026 | Viewed by 44 | Submission Open
Keywords: precision medicine; myocardial infarction; biomarkers; pharmacogenomics; cardiac imaging
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Approaches in Spinal Deformity: Innovations in Diagnosis and Treatment submission deadline 30 Oct 2026 | 1 articles | Viewed by 1682 | Submission Open
Keywords: adult spinal deformity; preoperative planning; minimally invasive spine surgery; sagittal malalignment; patient-specific hardware; precision medicine; personalized treatment
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Artificial Intelligence and Advanced Medical Imaging in Personalized Medicine
edited by Paul Andrei Ștefan and Diana Feier
submission deadline 30 Oct 2026 | Viewed by 203 | Submission Open
Keywords: artificial intelligence; medical imaging; personalized medicine; textural analysis; radiomics
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Challenges and Opportunities in Personalized Management of Rheumatic Diseases
edited by
submission deadline 30 Oct 2026 | Viewed by 43 | Submission Open
Keywords: rheumatic diseases; autoimmunity; osteoarthritis; psoriatic arthritis; personalized therapy; immune endotypes; machine learning; musculoskeletal ultrasound; patient preferences; treatment response biomarkers
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Recent Research on Personalized Approaches to Clinical Therapeutics and Medication Safety
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 6787 | Submission Open
Keywords: clinical therapeutics; medication safety; pharmacotherapy; personalized medicine; treatment optimization; polypharmacy
(This special issue belongs to the Section Epidemiology)
Clinical Advances and Innovations in Reconstructive and Plastic Surgery
edited by Laura Răducu
submission deadline 31 Oct 2026 | 4 articles | Viewed by 6598 | Submission Open
Keywords: plastic surgery; breast reconstruction; robotics; microsurgery; burns injury
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Advancing Personalized Medicine: Targeting Oxidative Stress in Neurodegenerative Diseases
edited by Lucia Buccarello
submission deadline 31 Oct 2026 | 1 articles | Viewed by 2150 | Submission Open
Keywords: oxidative stress; neurodegeneration; biomarkers; neuroprotection; protein oxidation; neuroinflammation; protein degradation; personalized medicine; intracellular signaling; neuronal death
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Pain Medicine: Biomarkers and New Therapeutic Frontiers
edited by Gustavo Fabregat-Cid
submission deadline 31 Oct 2026 | Viewed by 272 | Submission Open
Keywords: pain medicine; biomarkers; omics; neuroimaging; pain phenotyping
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Precision Medicine in Obstetrics and Gynaecology
edited by
submission deadline 31 Oct 2026 | Viewed by 263 | Submission Open
Keywords: precision medicine; reproductive health; preeclampsia; gestational diabetes; ovarian cancer; targeted therapies; endometriosis
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Artificial Intelligence in Personalized Management of Cardiovascular Diseases submission deadline 31 Oct 2026 | Viewed by 251 | Submission Open
Keywords: artificial intelligence; cardiovascular disease; health determinants and outcomes; cost effectiveness; policy; ethics; and governance
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Medicine in Maternal–Fetal Care: From Cervical Insufficiency to Preterm Birth and Beyond
edited by
submission deadline 31 Oct 2026 | Viewed by 112 | Submission Open
Keywords: cervical insufficiency; preterm birth; personalized medicine; emergent cerclage; infection-controlled cerclage; maternal– fetal medicine; AI-based prediction platforms
(This special issue belongs to the Section Personalized Medical Care)
Personalized Management for Perioperative Anesthesia
edited by Esther A.C. Bouman
submission deadline 31 Oct 2026 | Viewed by 61 | Submission Open
Keywords: personalized anesthesia; perioperative medicine; precision pain management; artificial intelligence in anesthesia; post-procedural pain; cancer surgery; individualized risk assessment
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Medicine in ENT and AI
edited by Cristóbal Langdon
submission deadline 20 Nov 2026 | Viewed by 44 | Submission Open
Keywords: personalized ENT care; precision phenotyping and stratification; clinical decision support (AI-assisted); predictive modeling and outcome forecasting; real-world validation and implementation
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Precision Medicine in Anesthesia and Pain
edited by Paramita Basu
submission deadline 25 Nov 2026 | Viewed by 465 | Submission Open
Keywords: Neuropeptide Y; chronic pain; NPY receptors; therapeutics; anesthesia; precision medicine
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
New Perspectives on Personalized Treatment Strategies of Obstetrics and Gynecology Oncology submission deadline 25 Nov 2026 | Viewed by 57 | Submission Open
Keywords: personalized medicine; gynecologic oncology; precision oncology; biomarkers; fertility preservation
(This special issue belongs to the Section Precision Oncology)
Personalized Medicine in Neurosurgery: Novel Prospectives and Challenges
edited by Deepti Diwan
submission deadline 25 Nov 2026 | Viewed by 28 | Submission Open
Keywords: neurological surgery; brain injury; personalized medicine; precision medicine; neuro-oncology; cerebrovascular surgery; epilepsy surgery; genomics; radiomics; artificial intelligence; image-guided neurosurgery; molecular biomarkers; translational neuroscience; neuroethics; patient-centered care
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Precision Medicine in Hematology–Oncology: Recent Progress and Challenges
edited by Anthony M. Hunter and Nikolaos Papadantonakis
submission deadline 25 Nov 2026 | Submission Open
Keywords: oncology; hematology; precision medicine; personalized medicine; targeted therapy; molecular targets; immunotherapy
(This special issue belongs to the Section Precision Oncology)
New Updates and Challenges in Personalized Orthopaedics
edited by Stephen M. Mcdonnell and Rahul Bhattacharyya
submission deadline 30 Nov 2026 | Viewed by 46 | Submission Open
Keywords: knee arthroscopy; knee replacement; partial knee replacement (sometimes called knee resurfacing); revision knee replacement; ACL reconstruction; hip replacement surgery; hip arthroscopy; knee replacement; knee arthroscopy
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Advancing Personalized Medicine in Inflammatory Disorders of the Gut
edited by Yukihiro Yamaguchi
submission deadline 30 Nov 2026 | Viewed by 33 | Submission Open
Keywords: pediatric; inflammatory bowel disease (IBD); ulcerative colitis; Crohn’ s disease; Hirschsprung's disease; epigenetic; personalized; precision; precision nutrition; gut microbiota; artificial intelligence (AI)
(This special issue belongs to the Section Personalized Medical Care)
Molecular and Technological Horizons in Ophthalmology: Precision Medicine from Artificial Intelligence to Optogenetic Vision Restoration submission deadline 30 Nov 2026 | Viewed by 32 | Submission Open
Keywords: ophthalmology; precision medicine; biomolecules; artificial intelligence; optogenetics; retinal degeneration; gene therapy; neuroprosthetics; nanocarriers; molecular diagnostics; vision restoration
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
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