Special Issues

Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Artificial Intelligence for Personalized Medicine: Bridging Innovative Technologies and Patient-Centric Care submission deadline 31 May 2026 | 2 articles | Viewed by 6869 | Submission Open
Keywords: artificial intelligence (AI); personalized medicine; AI-driven diagnostics and treatment; personalized treatment; AI applications; genomics; proteomics and other omics technologies; machine/deep learning algorithms; drug discovery and development for personalized therapy; complex genomic data and mutation patterns; wearables and ioT devices
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Surgical Innovation and Advancement in Limb Extremities submission deadline 31 May 2026 | 3 articles | Viewed by 5937 | Submission Open
Keywords: hand surgery; wrist surgery; ankle surgery; foot surgery; innovation; joint replacement; arthroscopy; flaps; microsurgery
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Orthodontics and Oral Surgery in Personalized Medicine: 2nd Edition submission deadline 31 May 2026 | 1 articles | Viewed by 2781 | Submission Open
Keywords: oral surgery; orthodontic; aligners; maxillo facial surgery; dental disease; dental materials; orthodontic diseases; periodontology; oral implantology; regenerative tissue; growth factor; stem cells; bone regeneration; tissue regeneration; engineering; intraoral scan; personalized medicine
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
New Trends and Challenges in Pharmacogenomics Research
edited by
submission deadline 31 May 2026 | 2 articles | Viewed by 2531 | Submission Open
Keywords: drug development; polygenic risk scores; diversity and inclusion; complex disease management; implementation science; genetic ancestry; special populations; rare variants
(This special issue belongs to the Section Pharmacogenetics)
New Advances in Metabolic Diseases Diagnostics and Treatment: From Basic Research to Clinical Practice submission deadline 31 May 2026 | 1 articles | Viewed by 2499 | Submission Open
Keywords: metabolic disease; inherited metabolic disease; mitochondrial metabolism; metabolomics; multi-omics; biomarkers
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Exploring Interventional Radiology: New Advances and Prospects
edited by
submission deadline 31 May 2026 | 2 articles | Viewed by 2462 | Submission Open
Keywords: interventional radiology; embolization; innovative techniques; minimally invasive procedures; long-term safety; prostate cancer; vascular anomalies; clinical outcomes; health economics; epidemiology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Traumatic Brain Injury: Complications and Outcomes of Precision Medicine submission deadline 31 May 2026 | 1 articles | Viewed by 1880 | Submission Open
Keywords: biomarkers; genetic polymorphisms; neuromonitoring; neuroradiology; microbiome
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Arthroplasty and Personalized Medicine: Updates and Challenges
edited by and Michela Saracco
submission deadline 31 May 2026 | Viewed by 1143 | Submission Open
Keywords: personalized medicine; personalized orthopedic surgery; primary and revision arthroplasties; personalized orthoplastic approach; personalized orthobiology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Precision Medicine in Thoracic Oncology: Targeted Therapies and Personalized Treatment Strategies
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 559 | Submission Open
Keywords: thoracic oncology; thoracic tumors; translational research; target therapies
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine for Breast Cancer: Update and New Challenge
edited by Arya Mariam Roy and Daniel Stover
submission deadline 31 May 2026 | Viewed by 80 | Submission Open
Keywords: personalized Medicine; tumor genomics; biomarker discovery; targeted therapy therapy resistance antibody-drug conjugates; genomic profiling; liquid biopsy; therapeutic sequencing
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine in Geriatrics and Gerontology: Prevention, Treatment and Multidisciplinary Research
edited by Dana Crisan, Valer Donca and
submission deadline 31 May 2026 | Viewed by 76 | Submission Open
Keywords: geriatrics; geriatric medicine; gerontology; personalized medicine; elderly; frailty; geriatric patients; aging process; cardiovascular diseases; renal system diseases; rheumatologic diseases; pharmacology; infectious diseases
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Medicine in Orthopedics and Traumatology: Progress and Challenges
edited by Federico Canavese, and
submission deadline 31 May 2026 | Viewed by 59 | Submission Open
Keywords: orthopedics; traumatology; personalized medicine; patient-specific treatments; custom implants; regenerative medicine; biomechanics; predictive modeling; personalized rehabilitation
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Diagnostics and Therapeutics in Otolaryngology
edited by Enrique Zapater-Latorre and
submission deadline 31 May 2026 | Viewed by 49 | Submission Open
Keywords: otology; head and neck cancer; personalized medicine; rhinology; laryngology; facial plastic surgery; sleep medicine; artificial intelligence; precision diagnosis
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Heart Failure: Personalized Diagnosis, Treatment and Management
edited by Edgardo J. Kaplinsky
submission deadline 31 May 2026 | Viewed by 38 | Submission Open
Keywords: heart failure; personalized diagnosis; heart disease; myocardial structure; myocardial function; cardiomyopathies; chronic heart failure; clinical cardiology
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Management of Abdominal Surgery and Complications
edited by Ioannis Mantzoros and
submission deadline 31 May 2026 | Viewed by 37 | Submission Open
Keywords: personalized medicine; abdominal surgery; complications; emergency; innovative surgery
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
New Advances in Cardiothoracic Surgery: Personalized Treatment and Management submission deadline 31 May 2026 | Viewed by 23 | Submission Open
Keywords: complex aortic surgery; valvular heart disease; endocarditis; individualized; open heart surgery; minimally invasive techniques; artificial intelligence
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Diagnosis and Treatment for Head and Neck Cancer
edited by
submission deadline 10 Jun 2026 | Viewed by 58 | Submission Open
Keywords: biomarker; precision diagnosis; head and neck cancer; oral cancer
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Diabetes and Its Complications: From Research to Clinical Practice submission deadline 20 Jun 2026 | 1 articles | Viewed by 2448 | Submission Open
Keywords: diabetes; cardiovascular diseases; kidney disorders; liver diseases; obesity; aging; diabetes medications
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Multiple Pregnancies: Optimal Follow-Up, Early Detection and Management of Complications, and Appropriate Mode and Time of Delivery submission deadline 20 Jun 2026 | 1 articles | Viewed by 1931 | Submission Open
Keywords: multiple pregnancy; twin pregnancy; triplet pregnancy; monochorionic pregnancy; monochorionic twins; monochorionic monoamniotic pregnancy; monochorionic diamniotic pregnancy; dichorionic diamniotic pregnancy; quadruplet pregnancy; chorionicity; amnionicity; conjoined twins; in vitro fertilization; assisted reproductive techniques; advanced maternal age; natural conception; pregnancy dating; aneuploidy screening; twin-to-twin transfusion syndrome (TTTS); fetal growth restriction (FGR); selective fetal growth restriction (sFGR); twin anemia-polycythemia sequence (TAPS); twin reversed arterial perfusion sequence (TRAP); fetoscopy; laser ablation; fetal laser therapy; laser therapy; bipolar cord coagulation; radiofrequency ablation; selective feticide; elective fetal reduction; elective termination of pregnancy; discordant fetal anomaly; structural abnormalities; single intrauterine fetal demise; cerclage; threatened preterm labor; preterm birth; preeclampsia; gestational hypertension; gestational diabetes; fetal ultrasound; fetal therapy; delivery; vaginal delivery; operative vaginal delivery; cesarean section; adverse perinatal outcomes
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
The Future of Personalized Orthodontics
edited by and Loredana Golovcencu
submission deadline 20 Jun 2026 | Viewed by 39 | Submission Open
Keywords: personalized orthodontics; clear aligner therapy; AI-driven orthodontics; digital orthodontic planning; skeletal anchorage systems; surgery-first approach; 3D imaging in orthodontics; customized biomechanics; interdisciplinary treatment in orthodontics; precision orthodontics
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advances in Physiologically Based Pharmacokinetics submission deadline 20 Jun 2026 | Viewed by 35 | Submission Open
Keywords: personalized medicine; precision dosing; mechanistic modeling and simulation; microphysiological systems; pharmacokinetics
(This special issue belongs to the Section Pharmacogenetics)
Gynecological Oncology: Personalized Diagnosis and Therapy
edited by Stuart Rundle and Ali Kucukmetin
submission deadline 25 Jun 2026 | 3 articles | Viewed by 3532 | Submission Open
Keywords: gynaecologic oncology; surgical oncology; medical oncology; radiation oncology; clinical oncology; palliative medicine; diagnosis; translational research; stratification; patient selection; genomics
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine for Rheumatic Diseases
edited by Rossella De Angelis, and Emilio Filippucci
submission deadline 25 Jun 2026 | 2 articles | Viewed by 2220 | Submission Open
Keywords: chronic arthritis; rheumatoid arthritis; seronegative arthritis; crystal arthropathies; connective tissue diseases; autoimmunity; laboratory medicine; ultrasound; nailfold capillaroscopy; clinimetric tools
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Child and Adolescent Psychiatry: Latest Research, Prevention and Treatment
edited by
submission deadline 25 Jun 2026 | Viewed by 90 | Submission Open
Keywords: child and adolescent psychiatry; mental health; sleep disturbances; depression; anxiety; eating disorders
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Diagnosis and Treatment in Sports Medicine
edited by Maria Ruberto and
submission deadline 25 Jun 2026 | Viewed by 27 | Submission Open
Keywords: personalized sports medicine; athlete-specific diagnostics; tailored treatment protocols; sports injury prevention; biomechanical analysis; digital health in athletics; wearable health technologies
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Approaches in Endocrine Surgical Innovation
edited by Leonardo Rossi
submission deadline 25 Jun 2026 | Viewed by 26 | Submission Open
Keywords: minimally invasive surgery; ablative treatments; robotic thyroidectomy; thyroid cancer; parathyroid disorders; adrenal tumors; active surveillance; medullary thyroid carcinoma; personalized endocrine care
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Precision Medicine in Dentistry and Oral Surgery
edited by Inês Francisco, and
submission deadline 25 Jun 2026 | Viewed by 16 | Submission Open
Keywords: precision medicine; dentistry; oral health; clinical research; personalized treatment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Genetic Counseling and Genome Sequencing in Pediatrics
edited by Monika Lejman
submission deadline 25 Jun 2026 | Viewed by 14 | Submission Open
Keywords: pediatric disease; genome sequencing; genetic counseling; personalized medicine; genetic diagnostics
(This special issue belongs to the Section Omics/Informatics)
Novel Insights in Diagnostics and Personalized Therapeutics in Obstetrics and Gynecology submission deadline 28 Jun 2026 | Viewed by 41 | Submission Open
Keywords: pregnancy complications; adverse pregnancy outcomes; preeclampsia; preterm labor; gynecologic oncology; minimal invasive endoscopic surgery
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Review Special Issue: Recent Advances in Personalized Medicine submission deadline 30 Jun 2026 | 3 articles | Viewed by 14335 | Submission Open
Keywords: personalized medicine; omics; informatics; pharmacogenetics; clinical medicine; cell; organism physiology; epidemiology; mechanisms of diseases; methodology; drug and device discovery; personalized therapy; drug delivery; evidence-based medicine; regenerative medicine and therapeutics; epigenetic therapy; sex-; gender- and hormone-based medicine; disease biomarker; personalized critical care; molecular targeted therapy
Precision Medicine for Digestive Diseases submission deadline 30 Jun 2026 | 3 articles | Viewed by 5543 | Submission Open
Keywords: colorectal cancer; esophageal cancer; gastric cancer; pancreatic cancer; liver and biliary tract cancer; biomarkers; tissue biopsy; liquid biopsy; precision medicine
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
New Perspectives and Current Challenges in Myocardial Infarction
edited by and Wojciech Wańha
submission deadline 30 Jun 2026 | 3 articles | Viewed by 5170 | Submission Open
Keywords: myocardial infarction  ; personalized medicine  ; artificial intelligence; genetics  ; targeted treatment; percutaneous coronary intervention
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advances in Personalized Diagnosis and Treatment in Dermatology
edited by Anna Belloni Fortina
submission deadline 30 Jun 2026 | 1 articles | Viewed by 3278 | Submission Open
Keywords: personalized dermatology; dermatological treatments; rare skin diseases; pediatric dermatology; dermatological care in organ transplant recipients; atopic dermatitis; contact sensitization; psoriasis; clinical and epidemiological studies in dermatology; immunological aspects of skin diseases; technological advancements in dermatology; tailored therapeutic strategies; pigmented lesions
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
AI and Precision Medicine: Innovations and Applications
edited by and Nima Pouladi
submission deadline 30 Jun 2026 | 1 articles | Viewed by 2599 | Submission Open
Keywords: artificial intelligence; precision medicine; personalized medicine; genomic medicine; personal genomics; deep learning; machine learning; generative AI; medical AI; health AI
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Prevention, Diagnosis and Treatment of Skin Disorders
edited by , Beata Bergler-Czop and Emanuele Cigna
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1536 | Submission Open
Keywords: skin disorders; skin diseases; dermatology; dermoscopy; reflectance confocal microscopy; optical coherence tomography— LC-OCT; non-melanoma skin cancer; melanoma; photodynamic therapy; raynaud phenomenon; scleroderma
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Novel Challenges and Advances in Respiratory Diseases submission deadline 30 Jun 2026 | 1 articles | Viewed by 1340 | Submission Open
Keywords: respiratory diseases; pulmonary disorders; lung health; novel therapies; diagnostic advancements; COVID-19 impact; immunotherapy; respiratory infections; airway diseases; precision medicine
(This special issue belongs to the Section Mechanisms of Diseases)
Advances in Robotic Neurorehabilitation
edited by
submission deadline 30 Jun 2026 | Viewed by 487 | Submission Open
Keywords: robotic neurorehabilitation; traumatic brain injury; neuroplasticity; stroke; neurodegenerative diseases
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Treatment and Management of Sleep Apnea
edited by
submission deadline 30 Jun 2026 | Viewed by 433 | Submission Open
Keywords: obstructive sleep apnea; positive airway pressure treatment; upper airway surgery; pharmacological treatment; behavioral therapy; oral appliance
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Risk Stratification with Diagnostic and Prognostic Relevance for Heart Failure: New Perspectives and Challenges submission deadline 30 Jun 2026 | Viewed by 327 | Submission Open
Keywords: heart failure; cardiovascular prevention; risk stratification; cardiovascular pathology; diagnostic modalities; treatment targets
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Minimally Invasive Thoracic Surgery: Risk Assessment and Personalized Perioperative Management
edited by and Vannucci Jacopo
submission deadline 30 Jun 2026 | Viewed by 290 | Submission Open
Keywords: VATS; ERAS; sublobar resection; risk assessment; minimally invasive thoracic surgery
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Precision Medicine in Chronic Kidney Disease: Diagnostics, Treatment, and Outcomes
edited by
submission deadline 30 Jun 2026 | Viewed by 227 | Submission Open
Keywords: chronic kidney disease; clinical research; basic research; epidemiology; prevention; public awareness; diagnostics; treatment; outcomes
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Anesthesiology and Pain Management in Clinical Medicine: 2nd Edition
edited by
submission deadline 30 Jun 2026 | Viewed by 28 | Submission Open
Keywords: anesthesiology; pain management; clinical medicine; pharmacology; innovative techniques; evidence-based practices
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Medicine in Orthopedics and Traumatology: Updates and Challenges
edited by Jan Reinhard and Melanie Ardelt
submission deadline 30 Jun 2026 | Viewed by 24 | Submission Open
Keywords: personalized lumbar spine surgery; patient-specific implants in endoprosthetics; targeted drug delivery in spine and joint surgery; precision medicine in degenerative lumbar disorders; computer-assisted surgical planning; risk-adapted strategies in endoprosthetics; individualized rehabilitation after joint replacement; functional optimization in lumbar fusion and arthroplasty
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Mental Health: Diagnosis, Therapeutic Intervention and Patient Management in the Era of Personalized Medicine submission deadline 30 Jun 2026 | Viewed by 23 | Submission Open
Keywords: therapeutic interventions; patient management; personalized medicine; digital psychiatry; multidisciplinary care teams; com-munity mental health; affective disorders; psychotic disorders
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Prevention and Treatment of Cardiovascular Diseases submission deadline 30 Jun 2026 | Viewed by 19 | Submission Open
Keywords: precision medicine in cardiology; cardiovascular risk stratification; personalized therapeutics; omics technologies in CVD; digital health and cardiovascular care; lifestyle interventions for CVD; arterial stiffness and hypertension; biomarkers for cardiovascular diseases
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Knee Injuries: Personalized Diagnosis, Treatment and Management
edited by Gavin Wood and Fernando Diaz Dilernia
submission deadline 30 Jun 2026 | Viewed by 19 | Submission Open
Keywords: knee osteoarthritis; personalized medicine; precision diagnosis; partial and total knee arthroplasty; periprosthetic frac-ture; complications; functional outcomes; instability; survivorship; periprosthetic joint infection
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
New Insight into Aging and Geriatric Syndromes: Clinical Updates and Perspectives submission deadline 10 Jul 2026 | 6 articles | Viewed by 16374 | Submission Open
Keywords: gerodontology; dementia; mild cognitive impairment (MCI); frontotemporal dementia; frailty; late-life depression; sarcopenia; sensorial impairments; multimorbidity; oral frailty; longevity; biological aging
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Treatment of Neurological Diseases submission deadline 20 Jul 2026 | 1 articles | Viewed by 3706 | Submission Open
Keywords: neurological diseases; neurodegenerative diseases; Alzheimer’ s disease; Parkinson’ s disease; neurodegeneration; dementia; epilepsy
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Orthopedic Diseases: Surgical Treatments and Personalized Rehabilitation Strategies
edited by Eyal Yaacobi
submission deadline 20 Jul 2026 | 1 articles | Viewed by 736 | Submission Open
Keywords: orthopedic treatment; surgical technics; limb salvage; rehabilitation
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Orthopedic Diseases: Advances in Limb Reconstruction
edited by Taylor J. Reif and Jason Shih Hoellwarth
submission deadline 20 Jul 2026 | 1 articles | Viewed by 667 | Submission Open
Keywords: limb lengthening; limb deformity; malunion; nonunion; limb salvage; amputation reconstruction; osseointegration; osteomyelitis; patient-specific surgery; patient-specific instrumentation
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
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