Special Issues

Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Personalized Approaches in Neurosurgery
edited by Alessandro Boaro and Marco Mammi
submission deadline 25 Aug 2025 | 1 articles | Viewed by 941 | Submission Open
Keywords: neurosurgery; neuronavigation; neuro-imaging; clinical outcomes; machine learning
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Gynecological Oncology: Personalized Diagnosis and Therapy
edited by Stuart Rundle and Ali Kucukmetin
submission deadline 25 Aug 2025 | Viewed by 330 | Submission Open
Keywords: gynaecologic oncology; surgical oncology; medical oncology; radiation oncology; clinical oncology; palliative medicine; diagnosis; translational research; stratification; patient selection; genomics
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Therapeutic Strategies in Gastrointestinal Surgery
edited by Francesco Santullo
submission deadline 25 Aug 2025 | Viewed by 91 | Submission Open
Keywords: surgical oncology; cytoreductive surgery; laparoscopic surgery; colorectal surgery; gastric cancer; hipec; pipac; peritoneal metastases
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Diagnosis and Management of Stroke
edited by Rubens José Gagliardi
submission deadline 25 Aug 2025 | Viewed by 64 | Submission Open
Keywords: stroke; cerebrovascular disease; carotid disease; epidemiology
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Novel Therapeutic Approaches to Asthma in Clinical Medicine
edited by Howraman Meteran
submission deadline 25 Aug 2025 | Viewed by 62 | Submission Open
Keywords: asthma management; novel asthma therapies; biologic treatments for asthma; personalized medicine in asthma; monoclonal antibodies; severe asthma; precision medicine; immune-modulating therapies; gene therapy in asthma; innovative drug delivery systems; microbiome and asthma; inflammation control in asthma; asthma biomarkers; airway remodeling; corticosteroid alternatives
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Medicine in Orthopaedics, 2nd Edition submission deadline 30 Aug 2025 | 7 articles | Viewed by 10490 | Submission Open
Keywords: outcomes; orthopedic surgery; traumatology; radiography; complication
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Advances in Animal Models and Precision Medicine for Cancer Research
edited by and
submission deadline 30 Aug 2025 | Viewed by 351 | Submission Open
Keywords: animal models; cancer; precision medicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Prevention of Gallbladder Cancer submission deadline 31 Aug 2025 | 3 articles | Viewed by 25595 | Submission Open
Keywords: gallbladder cancer; personalized prevention; risk biomarker; primary prevention; secondary prevention/early detection; tertiary prevention/avoidance of gallbladder cancer progression
(This special issue belongs to the Section Mechanisms of Diseases)
New Perspectives, Challenges and Innovations in Modern Personalized Gynaecologic Oncology submission deadline 31 Aug 2025 | 2 articles | Viewed by 7567 | Submission Open
Keywords: gynecologic oncology; surgical oncology; medical oncology; radiation oncology; diagnosis; ethics; palliative treatment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Cold Perspectives: Advancements and Applications of Cryotherapy in Clinical Settings submission deadline 31 Aug 2025 | 4 articles | Viewed by 5915 | Submission Open
Keywords: cryotherapy; local cryotherapy; cryostimulation; partial/local/whole-body cryostimulation; par-tial/local/whole-body cryotherapy; personalized rehabilitation; multidisciplinary rehabilitation; cold therapy; cold exposure; adjuvant therapy
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Novel Challenges and Advances in Orthopaedic and Trauma Surgery submission deadline 31 Aug 2025 | 3 articles | Viewed by 5199 | Submission Open
Keywords: orthopaedic surgery; traumatology; musculoskeletal disorders; innovation in orthopaedics; individualised treatment; post-operative rehabilitation; clinical research
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Medicine in Otolaryngology: Special Topic Otology—2nd Edition submission deadline 31 Aug 2025 | 3 articles | Viewed by 5020 | Submission Open
Keywords: cochlear implants in children; adults; and older adults; active middle-ear implants in children; adults; and the elderly; new indications in otology; active transcutaneous bone conduction implants in children; adults; and the elderly; hearing loss and cholesteatoma; implantable and non-implantable solutions for malformations; age-related hearing loss; single-sided deafness; cochlear implantation; otitis media; tinnitus; quality of life; burden of hearing loss; genetics and epigenetics of hearing loss; robotic surgery; novel biomarkers for the diagnosis and prognosis of hearing loss; novel intra-operative objective measures for hearing implants; alternative treatment options to implantable devices; MRI
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Progress on Personalized Diagnosis and Treatment of Osteoarthritis submission deadline 31 Aug 2025 | 3 articles | Viewed by 4539 | Submission Open
Keywords: osteoarthritis; knee osteoarthritis; hip osteoarthritis; osteoarthritis diagnosis; osteoarthritis treatment; conservative osteoarthritis treatment; surgical osteoarthritis treatment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Biomedical Tools in Diagnosis and Personalized Therapy of Cardiovascular Disease
edited by Nikolaos Koumallos and Konstantinos A. Aznaouridis
submission deadline 31 Aug 2025 | 1 articles | Viewed by 2441 | Submission Open
Keywords: cardiovascular disease; diagnosis; personalized therapy; biomedical tools; cardiovascular imaging
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Clinical Advances in Diagnosis and Personalized Treatments of Chronic Kidney Diseases submission deadline 31 Aug 2025 | 1 articles | Viewed by 2211 | Submission Open
Keywords: biomarkers for early diagnosis; genetic testing; precision medicine approaches; novel therapies; telemedicine and remote monitoring; nutritional interventions; regenerative medicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Clinical Advances in Traumatic Brain Injury and Concussion
edited by Spencer W. Liebel
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1351 | Submission Open
Keywords: traumatic brain injury; concussion; personalized medicine; neuroimaging; cognitive functioning; depression; connectomics; brain injury treatment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Clinical Updates on Personalized Upper Gastrointestinal Endoscopy submission deadline 31 Aug 2025 | 1 articles | Viewed by 1123 | Submission Open
Keywords: operative endoscopy; post-surgical complications; achalasia; Zenker diverticulum; GERD; gastroparesis
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Precision Medicine in Chronic Kidney Disease: Diagnostics, Treatment, and Outcomes
edited by
submission deadline 31 Aug 2025 | Viewed by 131 | Submission Open
Keywords: chronic kidney disease; clinical research; basic research; epidemiology; prevention; public awareness; diagnostics; treatment; outcomes
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Medicine in the ICU—2nd Edition submission deadline 10 Sep 2025 | 1 articles | Viewed by 1625 | Submission Open
Keywords: ARDS; mechanical ventilation; respiratory mechanics; monitoring; ultrasonography; respiratory muscles; diaphragm; cardiomyopathy; arrhythmias; sepsis; blood stream infections; antimicrobial resistance; ventilator-associated pneumonia; neuromonitoring; MODS; COVID-19
(This special issue belongs to the Section Personalized Critical Care)
Colorectal Cancers: Clinical and Therapeutical Updates and Challenges
edited by , and Adrian Constantin
submission deadline 10 Sep 2025 | Viewed by 371 | Submission Open
Keywords: colorectal cancer; clinical research; translational research; cancer biomarker; targeted therapy; medical imaging; colorectal surgery
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
New Advances in Techniques and Personalized Medicine in Cardiology
edited by
submission deadline 10 Sep 2025 | Viewed by 106 | Submission Open
Keywords: cardiovascular precision therapy; cardiovascular pharmacological therapy; pharmacogenetics; cardio-imaging; epigenetics; personalized medicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Diagnosis and Treatment of Oligometastatic Disease
edited by
submission deadline 15 Sep 2025 | Viewed by 334 | Submission Open
Keywords: oligometastatic disease; oligorecurrence; oligoprogression; oligoconsolidation; metastasectomy; stereotactic body radiotherapy (SBRT); novel systemic agents; target therapies; chemotherapy; immunotherapy
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Trauma Surgery: Strategies, Challenges and Vision of the Future
edited by and Yaniv S. Warschawski
submission deadline 20 Sep 2025 | 2 articles | Viewed by 2899 | Submission Open
Keywords: orthopaedic surgery; fractures; injuries; upper limb; trauma
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advances of Precision Medicine in Oncology submission deadline 25 Sep 2025 | 2 articles | Viewed by 5251 | Submission Open
Keywords: precision medicine; personalized cancer care; circulating tumor cells; biomolecules; liquid biopsies; omics technologies; biomarkers
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Cutting-Edge Diagnostics: The Impact of Imaging on Precision Medicine
edited by
submission deadline 25 Sep 2025 | 1 articles | Viewed by 2373 | Submission Open
Keywords: advanced imaging techniques; AI-enhanced imaging; molecular imaging; imaging biomarkers; precision medicine; personalized diagnostics; early disease detection; imaging data integration; genomics and imaging; imaging-guided interventions; clinical imaging applications; comparative imaging effectiveness; innovative imaging technologies; medical imaging advances; diagnostic accuracy; patient-specific imaging; functional imaging; quantitative imaging; radiomics; theranostics
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Current Updates on Arrhythmia and Cardiac Electrophysiology
edited by Georgios Leventopoulos and
submission deadline 25 Sep 2025 | 1 articles | Viewed by 1458 | Submission Open
Keywords: ablation energy mode; conduction system pacing; pulsed field ablation; leadless pacing; resynchronization; myocardial work; atrial fibrillation
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Pathological Mechanism of Breast Cancer
edited by
submission deadline 25 Sep 2025 | Viewed by 279 | Submission Open
Keywords: breast cancer; metastatic breast cancer; biomarkers; molecular profiling; immune landscape; genomics; personalized treatment; targeted therapy
(This special issue belongs to the Section Mechanisms of Diseases)
Advances in Interventional Radiology in Oncology
edited by
submission deadline 25 Sep 2025 | Viewed by 275 | Submission Open
Keywords: artificial intelligence; oncological imaging; hybrid imaging; endovascular radiology; percutaneous procedures; radiomics; MRI; CT; PET/CT; photon-counting CT; cone-beam CT
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Orthopedic Diseases: Advances in Limb Reconstruction
edited by Taylor J. Reif and Jason Shih Hoellwarth
submission deadline 25 Sep 2025 | Viewed by 83 | Submission Open
Keywords: limb lengthening; limb deformity; malunion; nonunion; limb salvage; amputation reconstruction; osseointegration; osteomyelitis; patient-specific surgery; patient-specific instrumentation
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
The Applications of Non-Invasive Brain Stimulation in Neuropsychiatric Research and Treatment submission deadline 25 Sep 2025 | Viewed by 70 | Submission Open
Keywords: neuroscience; non-invasive brain stimulation; rehabilitation; neuropsychiatric; neurophysiology; neuropsychology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Medicine in Pathological Diagnosis submission deadline 25 Sep 2025 | Viewed by 58 | Submission Open
Keywords: personalized medicine; pathology; pathological; trauma; toxicology; informed consent
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Neuroimaging Biomarkers for Precision Medicine in Neuropsychiatry: A Multidisciplinary Update
edited by
submission deadline 25 Sep 2025 | Viewed by 55 | Submission Open
Keywords: neuroimaging; neuropsychiatry; psychiatry; psychology; neuroscience; biomarkers; precision medicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Precision Medicine in Neuro-Imaging: Advances and Challenges
edited by Onur Tanglay
submission deadline 25 Sep 2025 | Viewed by 32 | Submission Open
Keywords: neuroimaging; precision medicine; biomarkers; brain health; neurotechnology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
How to Undertake Personalized Assessments and Cures for Pain
edited by Barbara Rocca and
submission deadline 30 Sep 2025 | 5 articles | Viewed by 8968 | Submission Open
Keywords: pain; suffering; personalization; evaluation; treatment; outcome; medicine; surgery; rehabilitation; psychology
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Head and Neck Oncologic Surgery: Clinical Updates and New Perspectives in Precision Medicine Era
edited by Filippo Carta and Roberto Puxeddu
submission deadline 30 Sep 2025 | 3 articles | Viewed by 6190 | Submission Open
Keywords: head and neck cancer; squamous cell carcinoma; free flap; microsurgery; oral cancer; laryngeal cancer; pharyngeal cancer; skin cancer; salivary gland cancer; precision medicine; personalized medicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
United Airway Disease: Current Perspectives submission deadline 30 Sep 2025 | 1 articles | Viewed by 2180 | Submission Open
Keywords: chronic rhinosinusitis; asthma; personalized medicine; type-2 inflammation; united airway; obstructive sleep apnoea; monoclonal antibodies; endotype; rhinology
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Treatment of Neurological Diseases
edited by Theodora Afrantou, and
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1321 | Submission Open
Keywords: neurological diseases; neurodegenerative diseases; Alzheimer’ s disease; Parkinson’ s disease; neurodegeneration; dementia; epilepsy
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Updates on Heart Valve Diseases: Personalized Treatment and Management
edited by Chiara Tessari
submission deadline 30 Sep 2025 | 1 articles | Viewed by 937 | Submission Open
Keywords: heart valve disease; congenital heart valve disease; transcatheter valve implantation/replacement; surgical technique; device technology; tissue engineering; structural valve deterioration; device failure/success
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
New Progress in Prevention and Personalized Treatment for Cardiovascular Diseases submission deadline 30 Sep 2025 | Viewed by 286 | Submission Open
Keywords: vascular medicine; hypertension; heart failure; multimorbidity; lifestyle changes; venous thromboembolic disease (VTE); cardiovascular risk; chronic coronary artery disease; cardiovascular therapy; atherosclerosis; systemic inflammation
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine in Infectious Diseases submission deadline 30 Sep 2025 | Viewed by 114 | Submission Open
Keywords: infectious diseases; genetic predisposition; post-acute infection syndromes; long-COVID; response; potential adverse events; and duration of protection of vaccines; response to therapy and development of resistance; personalized medicine; precision diagnostics; treatment strategies
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Orthopedic Diseases: Surgical Treatments and Personalized Rehabilitation Strategies
edited by Eyal Yaacobi
submission deadline 30 Sep 2025 | Viewed by 82 | Submission Open
Keywords: orthopedic treatment; surgical technics; limb salvage; rehabilitation
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advance on Prenatal Diagnosis and Maternal Fetal Medicine
edited by Themistoklis I. Dagklis
submission deadline 30 Sep 2025 | Viewed by 66 | Submission Open
Keywords: prenatal diagnosis; maternal– fetal medicine; fetal anomalies; genetic screening; fetal imaging; non-invasive prenatal testing (NIPT); obstetric care; perinatal outcomes; diagnostic technologies; artificial intelligence
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Clinical Advances in Neurooncology and Personalized Neurosurgery
edited by Csaba Zsolt Oláh and László Sipos
submission deadline 30 Sep 2025 | Viewed by 38 | Submission Open
Keywords: neuro-oncology; brain surgery; spine surgery; surgical techniques; quality of life; patient outcomes; interdisciplinary treatment; artificial intelligence; cutting-edge oncological treatments; radiotherapy; radiosurgery; microbiome aneurysm; perimesencephalic subarachnoid hemorrhage; COVID; microbiome; brain abscess; bacterium; fungi
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Medicine in Reproduction and Fertility
edited by Nikos K. Nikolettos
submission deadline 10 Oct 2025 | Viewed by 82 | Submission Open
Keywords: personalized medicine; fertility; assisted reproduction; reproductive health
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine in Metabolism Disorders
edited by Mehrnaz Abbasi
submission deadline 10 Oct 2025 | Viewed by 29 | Submission Open
Keywords: metabolic syndrome; obesity; insulin resistance; hypertension; type 2 diabetes; energy metabolism; fatty acid oxida-tion; gut microbiota; brown adipose tissue (BAT); white adipose tissue (WAT); nutritional interventions; lifestyle modifications; pharmacological treatments; phytochemicals; vitamins and supplements; public health; epidemiology of obesity; preventive strategies; genetic factors; metabolic health research; adipose tissue function
(This special issue belongs to the Section Mechanisms of Diseases)
Dermatology: Molecular Mechanisms, Diagnosis and Therapeutic Targets submission deadline 15 Oct 2025 | 1 articles | Viewed by 1534 | Submission Open
Keywords: dermatologic diseases; atopic dermatitis; psoriasis; hidradenitis suppurativa; vitiligo; alopecia; melanoma; scleroderma
(This special issue belongs to the Section Molecular Targeted Therapy)
Exploiting Metabolic Weaknesses: A Novel Approach to Overcome Drug Resistance in Cancer Therapy
edited by
submission deadline 15 Oct 2025 | 1 articles | Viewed by 981 | Submission Open
Keywords: drug resistance; tumor metabolism; immunometabolism; metabolomics; metabolites; precision medicine
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Multiple Biomarkers for the Diagnosis and Precision Treatment of Depression
edited by
submission deadline 15 Oct 2025 | Viewed by 315 | Submission Open
Keywords: depression; biomarkers; inflammation; autoimmunity; genomics; physiology; radiography
(This special issue belongs to the Section Disease Biomarker)
Novel Applications of Artificial Intelligence in Personalized Medicine
edited by Aikaterini Sakagianni
submission deadline 15 Oct 2025 | Viewed by 45 | Submission Open
Keywords: artificial intelligence  ; personalized medicine  ; predictive modeling  ; genomics  ; proteomics  ; AI-driven diagnostics  ; patient-specific treatment  ; drug discovery  ; healthcare innovation  ; clinical applications of AI
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Gestational Diabetes: Challenges and Cutting-Edge Research submission deadline 15 Oct 2025 | Viewed by 40 | Submission Open
Keywords: gestational diabetes; continuous glucose monitor; fetal health; pregnancy; macrosomia; personalized management
(This special issue belongs to the Section Mechanisms of Diseases)
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