Special Issues

Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Towards Personalized Medicine in Breast Cancer
edited by Eun Young Kim
submission deadline 31 Oct 2025 | Viewed by 88 | Submission Open
Keywords: personalized medicine; breast cancer; targeted therapy; immunotherapy; pharmacogenomics; biomarkers; treatment resistance; early detection
(This special issue belongs to the Section Mechanisms of Diseases)
Precision Medicine in Neurodevelopmental Disorders: Challenges and Opportunities
edited by Song-Yu Yang, Xue-Ying He and Manfred Philipp
submission deadline 31 Oct 2025 | Viewed by 74 | Submission Open
Keywords: intellectual disability; inborn metabolic disorders; X-linked disorders; retarded growth; mitochondrial diseases; genetic and genomic disorders
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Chronic Obstructive Pulmonary Disease (COPD): From Diagnosis and Comorbidities to Personalized Management and Palliative Care
edited by and Florin Mihaltan
submission deadline 10 Nov 2025 | 2 articles | Viewed by 9524 | Submission Open
Keywords: risk factors; systemic inflammation; phenotypes; cardio-pulmonary functional assessment; comorbidities; exacerbations; treatment; rehabilitation; prognosis tools; palliative care; management
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Chemotherapy and Hematopoietic Stem Cell Transplantation
edited by
submission deadline 15 Nov 2025 | Viewed by 77 | Submission Open
Keywords: hematopoietic stem cell transplantation; chemotherapy toxicity and conditioning regimens; graft-versus-host disease (GVHD) management; immunotherapy and cellular therapies
(This special issue belongs to the Section Regenerative Medicine and Therapeutics)
Ehealth, Telemedicine, and AI in the Precision Medicine Era
edited by
submission deadline 20 Nov 2025 | 3 articles | Viewed by 10978 | Submission Open
Keywords: digital health; artificial intelligence; telemedicine; telerehabilitation; E-health; precision medicine; remote monitoring; wearable devices; mobile health (mHealth); virtual health; health informatics; machine learning; predictive analytics; personalized medicine; health technology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Skin Pathophysiology and Management
edited by , Joanna Goldberg and Mahsa Babaei
submission deadline 20 Nov 2025 | 2 articles | Viewed by 5202 | Submission Open
Keywords: skin disease pathophysiology; skin disease diagnosis; skin disease treatment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Neurodegenerative Diseases: Molecular Pathology and Personalized Treatment submission deadline 20 Nov 2025 | 1 articles | Viewed by 501 | Submission Open
Keywords: neurodegeneration; molecular pathology; precision medicine; biomarkers; personalized therapeutics
(This special issue belongs to the Section Mechanisms of Diseases)
Mechanisms of Airway Inflammation in Asthma
edited by Kathleen Haley
submission deadline 20 Nov 2025 | Viewed by 365 | Submission Open
Keywords: asthma; inflammation in asthma; targeted therapies; acute respiratory distress syndrome; chronic lung diseases; critical care
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Liquid Biopsy in Lung Cancer: Innovations in Precision Oncology submission deadline 20 Nov 2025 | Viewed by 157 | Submission Open
Keywords: liquid biopsy; lung cancer; biomarkers; diagnosis; personalized treatment
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Medicine in Gynecology and Obstetrics submission deadline 25 Nov 2025 | 1 articles | Viewed by 1451 | Submission Open
Keywords: personalized medicine; genetic screening; risk assessment for pregnancy complications; fetal health monitoring; pharmacogenomics; hormone therapy; genetic testing for cancer risk fertility treatments; endometriosis; fibroid management; preventive care and screening
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Recent Advances in Bariatric Surgery
edited by and Andrea Peri
submission deadline 25 Nov 2025 | 1 articles | Viewed by 1338 | Submission Open
Keywords: bariatric surgery; morbid obesity; sleeve gastrectomy; gastric bypass; emerging procedures; early outcomes; long-term results
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Precision Medicine in Gynecological Endoscopy: From Personalized Diagnosis to Tailored Surgical Interventions
edited by and Dimitrios Zacharakis
submission deadline 25 Nov 2025 | 1 articles | Viewed by 686 | Submission Open
Keywords: gynecological endoscopy; minimally invasive and robotic surgeries; personalized gynecological care; gynecological healthcare; personalized diagnosis; genomic profiling; real-time imaging; AI algorithms; biomarker identification  
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Molecular Pathology in Cancer Research
edited by Maurizio Martini and Giuseppe Giuffré
submission deadline 25 Nov 2025 | 1 articles | Viewed by 477 | Submission Open
Keywords: molecular pathology; diagnostic pathology; cancer diagnosis; biomarkers; targeted therapy; genomics
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Clinical Management and Personalized Treatment in Digestive Surgery submission deadline 25 Nov 2025 | Viewed by 277 | Submission Open
Keywords: digestive disease; digestive cancers; gastrointestinal surgery; stomach; pancreas; liver
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Precision Medicine in Spine Surgery: Updates and Challenges
edited by Mark James Lambrechts
submission deadline 25 Nov 2025 | Viewed by 54 | Submission Open
Keywords: spine; orthopedic surgery; neurosurgery; precision; endoscopic spine; artificial disc replacement; spinal deformity; patient-specific alignment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Head and Neck Disease: Personalized Approaches to Screening and Diagnosis
edited by Heejin Kim
submission deadline 25 Nov 2025 | Viewed by 49 | Submission Open
Keywords: otolaryngology; head and neck; rhinosinusitis; thyroidectomy; tonsillectomy; personalized; screening; diagnosis
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Towards Precision Anesthesia and Pain Management
edited by , Joseph V. Pergolizzi and Filomena Puntillo
submission deadline 30 Nov 2025 | 3 articles | Viewed by 6742 | Submission Open
Keywords: precision medicine; anesthesia; pain medicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Computer-Assisted Diagnosis and Personalized Treatment of Fracture
edited by Juan Jiménez-Delgado
submission deadline 30 Nov 2025 | 2 articles | Viewed by 3088 | Submission Open
Keywords: fracture diagnosis; computer-assisted simulation; artificial intelligence in orthopedics; medical imaging advances; personalized fracture treatment; computational fracture analysis; surgical planning tools; virtual reality in orthopedics; forensic analysis of fractures; multiscale modeling of bone
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Clinical Advances and Innovations in Reconstructive and Plastic Surgery
edited by Laura Răducu
submission deadline 30 Nov 2025 | 2 articles | Viewed by 2258 | Submission Open
Keywords: plastic surgery; breast reconstruction; robotics; microsurgery; burns injury
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
New Insights into Personalized Medicine for Anesthesia and Pain
edited by and Guen Joo Choi
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1926 | Submission Open
Keywords: new insights; personalized medicine; anesthesia; pain management; perioperative analgesia; airway management; perioperative nausea; interventional pain care; critical care; minimally invasive surgery/robotic surgery; mechanical ventilation; chronic pain; acute pain; lumbar/cervical/thoracic/spinal pain; musculoskeletal pain
(This special issue belongs to the Section Personalized Critical Care)
Role of Genetic Tools in Diagnosis and Personalized Treatment for Neurological Diseases
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1585 | Submission Open
Keywords: neurological disorders; molecular modeling; bioinformatics; genetic tools; genetic variants; omic technologies; DNA sequencing; newborn screening; therapeutic procedure; mechanism of action
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Epigenetics in Precision Medicine: From Mechanism to Therapy submission deadline 30 Nov 2025 | 1 articles | Viewed by 856 | Submission Open
Keywords: epigenetics; precision medicine; methylation; histone modifications; non-coding RNA
(This special issue belongs to the Section Epigenetic Therapy)
Personalized Medicine in Gastrointestinal Surgical Oncology
edited by and Myoung-Won Son
submission deadline 30 Nov 2025 | 1 articles | Viewed by 521 | Submission Open
Keywords: personalized medicine; gastrointestinal surgical oncology; laparoscopic surgery; robotic surgery; AI in surgery; multimodal treatment; clinical trials; oncological outcomes
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Radiation Therapy for Cancers: Current Status and Future Perspectives
edited by Roberta Carbonara and
submission deadline 30 Nov 2025 | Viewed by 344 | Submission Open
Keywords: personalized radiotherapy; personalized oncology; adaptive radiotherapy; stereotactic radiotherapy; re-irradiation; immuno-radiotherapy; tumor microenvironment and radiotherapy
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Pain Medicine: Biomarkers and New Therapeutic Frontiers
edited by Gustavo Fabregat-Cid
submission deadline 30 Nov 2025 | Viewed by 92 | Submission Open
Keywords: pain medicine; biomarkers; omics; neuroimaging; pain phenotyping
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Precision Medicine in Obstetrics and Gynaecology
edited by
submission deadline 30 Nov 2025 | Viewed by 63 | Submission Open
Keywords: precision medicine; reproductive health; preeclampsia; gestational diabetes; ovarian cancer; targeted therapies; endometriosis
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Artificial Intelligence in Personalized Management of Cardiovascular Diseases submission deadline 30 Nov 2025 | Viewed by 56 | Submission Open
Keywords: artificial intelligence; cardiovascular disease; health determinants and outcomes; cost effectiveness; policy; ethics; and governance
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Otolaryngology in Clinical Practice: The Necessity of Personalized Medicine
edited by Jerome Rene Lechien
submission deadline 30 Nov 2025 | Viewed by 42 | Submission Open
Keywords: otolaryngology; otorhinolaryngology; artificial Intelligence; personalized Medicine; treatments
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Acute Myeloid Leukemia: Current Progress and Future Directions submission deadline 10 Dec 2025 | Viewed by 447 | Submission Open
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Complications in Vascular Surgery: Current Updates and Perspectives
edited by
submission deadline 10 Dec 2025 | Viewed by 113 | Submission Open
Keywords: endoleak; visceral ischaemia; lower limb ischaemia; graft infection; aneurysm shrinkage; sac growing; transient ischemic attack; stroke; deep vein thrombosis; vascular injuries; embolization
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advances in Oral Health: Innovative and Personalized Approaches
edited by , Heleni Vastardis and
submission deadline 15 Dec 2025 | Viewed by 50 | Submission Open
Keywords: artificial intelligence; machine learning; genetics; orthodontics; pediatric dentistry; preventive dentistry; periodontology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Medicine in Psychiatry: Challenges and Opportunities submission deadline 20 Dec 2025 | 5 articles | Viewed by 12156 | Submission Open
Keywords: psychiatry; personalized medicine; epidemiology; public health; addictions; schizophrenia; depression; mental health; precision psychiatry; treatment response; genetic factors; biomarkers; pharmacogenomics; behavioral interventions; comorbidity; substance abuse; neurobiology; psychiatric disorders; psychosocial factors; population health
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Advancements in Neurosurgical Oncology: Bridging Neurosurgery and Cancer Neuroscience submission deadline 20 Dec 2025 | 1 articles | Viewed by 5967 | Submission Open
Keywords: neuro-oncology; cancer progression; neural mechanisms in cancer; brain tumors; neurological implications of cancer; cancer-induced neuropathy; neural stem cells and cancer; neuroinflammation in cancer; neuroimaging in oncology; cancer therapeutics and neurological safety
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Plastic Surgery: New Perspectives and Innovative Techniques
edited by Joseph M. Escandón and
submission deadline 20 Dec 2025 | Viewed by 487 | Submission Open
Keywords: plastic surgery procedures; free tissue flaps; gender-affirmation surgery; reconstructive procedures; lymphedema; breast cancer; oncologic reconstruction; body contouring; regenerative medicine; stem cell therapy; aesthetic surgery
(This special issue belongs to the Section Regenerative Medicine and Therapeutics)
Integrating Mathematical Modeling and Data Analysis in Personalized Medical Research submission deadline 20 Dec 2025 | Viewed by 74 | Submission Open
Keywords: personalized medicine; health informatics; mathematical modeling; data analysis; bioinformatics; artificial intelligence; machine learning
(This special issue belongs to the Section Omics/Informatics)
Personalized Medicine in Dental and Oral Health submission deadline 25 Dec 2025 | 4 articles | Viewed by 8128 | Submission Open
Keywords: oral health; systemic context; personalized medicine; pharmacogenomics; caries pathology; diagnostics; clinical evaluation; paraclinical evaluation
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Laparoscopy, Perioperative Care and Complications in Surgery for Gastrointestinal Diseases
edited by Michał Kisielewski
submission deadline 25 Dec 2025 | 2 articles | Viewed by 3019 | Submission Open
Keywords: laparoscopy; perioperative care; colorectal surgery; minimally invasive surgery; upper digestive surgery; hepatobiliary surgery; postoperative complications
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Artificial Intelligence and Computational Approaches for Clinical Pharmacology and Drug Development
edited by Paraskevi F. Katsakiori and
submission deadline 25 Dec 2025 | 1 articles | Viewed by 1676 | Submission Open
Keywords: personalized medicine; artificial intelligence; optimized therapies; computational models; drug development; clinical pharmacology; machine learning; radiopharmaceuticals; prediction models; digital healthcare
(This special issue belongs to the Section Pharmacogenetics)
Targeted Therapy and Biomarkers for Solid Tumors
edited by Anca Zgură and
submission deadline 25 Dec 2025 | Viewed by 286 | Submission Open
Keywords: targeted therapy; biomarkers; solid tumors; oncology; cancer immunology; oncology radiotherapy; personalized medicine; molecular targets; drug resistance; translational research
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Diagnosis and Therapy in Renal Cell Carcinoma
edited by Antonio Nacchia
submission deadline 25 Dec 2025 | Viewed by 106 | Submission Open
Keywords: inflammation; kidney cancer; renal cell cancer; inflammatory markers
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Inflammatory Bowel Disease (IBD): Diagnosis and Personalized Treatment
edited by Abigail Raffner (formerly Basson)
submission deadline 25 Dec 2025 | Viewed by 97 | Submission Open
Keywords: inflammatory bowel disease; diagnostic tools; biomarkers; therapeutic strategies; molecular mechanisms; microbiome; genetic predispositions; environmental factors; personalized treatment
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Advancing Personalized Medicine: Targeting Oxidative Stress in Neurodegenerative Diseases
edited by Lucia Buccarello
submission deadline 25 Dec 2025 | Viewed by 74 | Submission Open
Keywords: oxidative stress; neurodegeneration; biomarkers; neuroprotection; protein oxidation; neuroinflammation; protein degradation; personalized medicine; intracellular signaling; neuronal death
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Medicine and Management of Gynecologic Cancer
edited by Hooman Soleymani majd and
submission deadline 25 Dec 2025 | Viewed by 68 | Submission Open
Keywords: proteomic; genomic; biomarkers; precision medicine; molecular profiling; immunotherapy; gynecologic cancer
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine in Otolaryngology: New Challenges and Future Perspectives
edited by Jerome Rene Lechien
submission deadline 25 Dec 2025 | Viewed by 60 | Submission Open
Keywords: otolaryngology; oral cancer; oncology; head and neck surgery; minimally invasive; laryngology; artificial intelligence; rhinology; ENT; personalized
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Plastic and Reconstructive Surgery: Challenges and Prospects
edited by Johnny Ionut Efanov and Alain Michel Danino
submission deadline 25 Dec 2025 | Viewed by 30 | Submission Open
Keywords: reconstructive surgery; plastic surgery; flaps reconstruction; breast reconstruction; 3D printing; personalized surgery; biomaterials; imaging-assisted surgery; robotics
(This special issue belongs to the Section Regenerative Medicine and Therapeutics)
Cancer Immunotherapy: Current Advancements and Future Perspectives submission deadline 31 Dec 2025 | 6 articles | Viewed by 12835 | Submission Open
Keywords: personalized immunotherapy; molecular pathways in cancer immunotherapy; precision medicine; molecular markers; molecular bases of abscopal effect; sustained therapeutic response
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Obstetrics and Gynecology and Women's Health—2nd Edition submission deadline 31 Dec 2025 | 2 articles | Viewed by 8240 | Submission Open
Keywords: uterine fibroids; uterine myoma; leiomyoma; uterine artery embolization; endometriosis; gynecological surgery; infertility; endocrinology; hysteroscopy; hormonal therapies; personalized medicine
(This special issue belongs to the Section Sex, Gender and Hormone Based Medicine)
Advancing Personalized Spine Surgery Through Minimally Invasive Techniques—Perspectives from Inter-American Society for Minimally Invasive Spine Surgery (SICCMI)
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 5155 | Submission Open
Keywords: spine surgery; minimally invasive techniques; personalized care; personalized medicine; precision imaging; 3D printing in orthopedics; biomarkers in spinal health; artificial intelligence in surgery; robotics in spine surgery; genomics and spinal disorders; pain management and rehabilitation; surgical navigation systems; biocompatible materials for implants; patient-specific surgical planning; regenerative medicine in spine health; future trends in spinal surgery
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Digital Pathology in Translational Medicine and Clinical Practice
edited by , and Filippo Fraggetta
submission deadline 31 Dec 2025 | 1 articles | Viewed by 2387 | Submission Open
Keywords: digital pathology; computational pathology; integrative pathology; computer-aided diagnosis; artificial intelligence; biomarker discovery
(This special issue belongs to the Section Mechanisms of Diseases)
Biomarkers and Pathogenesis of Infectious Diseases: From Research to Personalized Medicine
edited by César Henríquez-Camacho
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1666 | Submission Open
Keywords: biomarkers; infectious diseases; pathogenesis; personalized medicine
(This special issue belongs to the Section Disease Biomarker)
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