Special Issues

Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Clinical Practice and Future Trends of Oral and Maxillofacial Surgery
edited by Rocco Franco
submission deadline 31 Jan 2026 | Viewed by 79 | Submission Open
Keywords: oral and maxillofacial surgery; digital technology; regenerative medicine; artificial intelligence; personalized treatment.
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Precision Orthopedics: Evolving Shoulder, Hip, and Knee Surgery Through Intelligent Technology and Personalized Clinical Care
edited by Alessandra Berton
submission deadline 31 Jan 2026 | Viewed by 55 | Submission Open
Keywords: precision orthopedics; shoulder surgery; hip surgery; knee surgery; personalized medicine; artificial intelligence; robotic surgery; 3D printing; wearable sensors; patient outcomes
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Immunotherapy and Targeted Therapy in Gynecologic Cancer: Current Status and Challenges
edited by Brigida Anna Maiorano and
submission deadline 31 Jan 2026 | Viewed by 45 | Submission Open
Keywords: immunotherapy; targeted therapy; gynecologic cancer; vulvar cancer; biomarkers; immune checkpoint inhibitors; HPV-related tumors; personalized oncology
(This special issue belongs to the Section Molecular Targeted Therapy)
Personalized Medicine in Hematologic Malignancies: Advances and Prospects
edited by Khalil Saleh
submission deadline 31 Jan 2026 | Viewed by 39 | Submission Open
Keywords: CAR T-cells; bispecific antibodies; antibody– drug conjugates; bispecific T-cell engagers; artificial intelligence; mechanisms of resistance; biomarkers
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Complex and High-Risk Coronary Interventional Procedures
edited by , Toth-Gayor Gabor and
submission deadline 10 Feb 2026 | 1 articles | Viewed by 1592 | Submission Open
Keywords: complex high-risk intervention (CHIP); coronary bifurcation; coronary chronic total occlusion; severe coronary calcification; protected PCI; access site I during CHIP procedures
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Medicine in Endometriosis
edited by Christine Bekos
submission deadline 10 Feb 2026 | Viewed by 558 | Submission Open
Keywords: microbiome; epigenetics; fatigue; laparoscopic surgery; lifestyle changes; endometriosis
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Diagnosis and Treatment of Digestive System Disorders
edited by Gengqing Song
submission deadline 10 Feb 2026 | Viewed by 63 | Submission Open
Keywords: personalized medicine; gastrointestinal disorders; precision diagnostics; functional GI disorders; gastrointestinal motility; microbiome; pharmacogenomics; gastrointestinal oncology
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Application of Genetic Diagnosis in Pediatrics
edited by Avinash Veerappa
submission deadline 10 Feb 2026 | Viewed by 54 | Submission Open
Keywords: pediatric diagnosis; rare diseases; genome sequencing; exome sequencing; genetic diseases; mutations
(This special issue belongs to the Section Omics/Informatics)
The Development of Echocardiography in Heart Disease
edited by Jolanta Justina Vaskelyte, Egle Rumbinaite and Vaida Mizariene
submission deadline 20 Feb 2026 | 3 articles | Viewed by 6849 | Submission Open
Keywords: echocardiography; speckle tracking; CAD; valvular pathology; myocardial/pericardial diseases; congenital defects; rare cardiac diseases; interventional procedures
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Clinical Diagnosis and Treatment in Otorhinolaryngology
edited by Delia Hînganu and Marius Valeriu Hînganu
submission deadline 20 Feb 2026 | 2 articles | Viewed by 878 | Submission Open
Keywords: ENT surgery; multimodality imaging; prevention; voice formation; middle ear pathology; inner ear pathology
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Management and Treatment in Geriatrics submission deadline 20 Feb 2026 | Viewed by 123 | Submission Open
Keywords: geriatrics; personalized health care; artificial intelligence; comprehensive geriatric assessment; ageing; biomedical technology; health promotion; chronic disease management; rehabilitation; pharmacogenetics; neurodegenerative diseases
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine in Ophthalmology: Diagnosis, Prevention, and Treatment
edited by Antonio Di Zazzo and
submission deadline 25 Feb 2026 | 1 articles | Viewed by 3167 | Submission Open
Keywords: ocular surface; dry eye disease; scleral lenses; corneal disease; keratoconus
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine in Retinal Diseases
edited by Henrik Faatz
submission deadline 25 Feb 2026 | 3 articles | Viewed by 2989 | Submission Open
Keywords: retinal disease; age-related macular degeneration; diabetic retinopathy; gene therapy; retinal biomarker; personalized medicine; retinal imaging
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
New Insights into Personalized Care in Advance Care Planning submission deadline 25 Feb 2026 | 2 articles | Viewed by 1802 | Submission Open
Keywords: advance care planning; choices about future medical care; cultural differences; diversity; personalized care choices
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Novel Challenges and Advances in Pediatric Hematology and Hematologic Malignancies
edited by Katarzyna Pawińska-Wa̧sikowska
submission deadline 25 Feb 2026 | 1 articles | Viewed by 1779 | Submission Open
Keywords: pediatric hematology; hematology malignancies; therapies; diagnosis; immunotherapies; supportive care
(This special issue belongs to the Section Mechanisms of Diseases)
Precision Medicine in Gastrointestinal Neoplasms
edited by Juan Torres-Melero and
submission deadline 25 Feb 2026 | Viewed by 386 | Submission Open
Keywords: digestive cancers; molecular biology; gastrointestinal cancers; gynecological cancers
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advances in Precision Medicine of Oncology Radiotherapy
edited by and Silvana Parisi
submission deadline 25 Feb 2026 | Viewed by 168 | Submission Open
Keywords: novel radiotherapy approaches; novel drugs; novel diagnostic approaches; immunomodulation; omics; biomarkers; metabolic alterations; personalised medicine
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Breast Cancer: New Advances in Diagnosis and Personalized Therapies
edited by Pierluigi Maria Rinaldi and Sabatino D'Archi
submission deadline 25 Feb 2026 | Viewed by 87 | Submission Open
Keywords: breast cancer; Breast Imaging Reporting and Data System 3 (BI-RADS 3); imaging; radiomics; therapy; AI
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Multidisciplinary Management of Acute Trauma and Emergency Surgery
edited by Oluwafemi Patrick Owodunni
submission deadline 25 Feb 2026 | Viewed by 82 | Submission Open
Keywords: trauma; emergency surgery; acute care surgery; trauma systems; prehospital care; resuscitation; critical care; hem-orrhage control; damage control surgery; trauma outcomes
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Depression and Anxiety: Recent Advances in Personalized Treatment and Management
edited by
submission deadline 25 Feb 2026 | Viewed by 72 | Submission Open
Keywords: personalized treatment; mood disorders and anxiety; treatment; therapy; depression and anxiety
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Cancer Biomarker and Molecular Oncology
edited by
submission deadline 27 Feb 2026 | Viewed by 37 | Submission Open
Keywords: cancer biomarkers; molecular oncology; precision medicine; liquid biopsies; therapeutic resistance
(This special issue belongs to the Section Disease Biomarker)
Advances in Emerging Technologies for Rehabilitation: Personalized Perspective submission deadline 28 Feb 2026 | 5 articles | Viewed by 9835 | Submission Open
Keywords: virtual reality; mixed reality; augmented reality; robotic interventions; exoskeletons; eHealth; mHealth; wearable technology; telerehabilitation; remote support; barriers and challenges of new technologies in rehabilitation; psychosocial effects of new technology interventions; insights in novel approaches in technology-supported rehabilitation; biometric technology; personalized perspective
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Application of Artificial Intelligence in Personalized Medicine: Diagnosis and Treatment
edited by Abdulkader Helwan
submission deadline 28 Feb 2026 | 2 articles | Viewed by 5685 | Submission Open
Keywords: artificial intelligence (AI); personalized medicine; precision health; AI-driven diagnostics; machine learning; deep learning; predictive analytics; genomics; proteomics; biomarkers; patient-centric care; treatment personalization; healthcare data integration; drug discovery; real-time monitoring; ethical considerations in AI; individual variability; wearable technology; health informatics
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Breast Cancer: Current Trends and Future Challenges in Evaluation and Treatment
edited by Stefano Spinaci and Giulia Ferrarazzo
submission deadline 28 Feb 2026 | 3 articles | Viewed by 4808 | Submission Open
Keywords: breast cancer; breast surgery; conservative surgery; robotic breast techniques; male breast cancer
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Clinical Progress in Personalized Management of Cardiac Surgery
edited by Chiara Tessari and Augusto D'Onofrio
submission deadline 28 Feb 2026 | 2 articles | Viewed by 2355 | Submission Open
Keywords: clinical and hemodynamic evaluation of heart valve bioprostheses and tissue engineering; clinical and hemodynamic evaluation of heart valve repair techniques; advanced heart failure and surgical treatment options; immunological evaluation in heart transplant patients; cardiovascular regenerative medicine; telemedicine and artificial intelligence application in cardiac surgery
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advances in Atrial Fibrillation and Cardiac Arrhythmias: Mechanisms, Diagnosis, and Therapy
edited by Antonios P. Antoniadis and
submission deadline 28 Feb 2026 | 1 articles | Viewed by 519 | Submission Open
Keywords: atrial fibrillation; arrhythmias; pathophysiological mechanisms; electrophysiological; molecular mechanisms; novel approaches; diagnosis; risk prediction; therapeutic strategies; atrial fibrillation ablation; digital health; artificial intelligence; imaging; wearable devices
(This special issue belongs to the Section Mechanisms of Diseases)
Advances in Diagnostics and Management of Respiratory System Diseases
edited by and Chao-Tien Hsu
submission deadline 28 Feb 2026 | Viewed by 309 | Submission Open
Keywords: elderly; geriatric respiratory diseases; cardiovascular disease; metabolic disease; cancer
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Genomics and Precision Medicine
edited by and Louis Papageorgiou
submission deadline 28 Feb 2026 | Viewed by 113 | Submission Open
Keywords: genomics; precision medicine; diagnostics; treatment; genomic test; big data; genomic screening; genomic medicine; genomic biomarker; functional genomics
(This special issue belongs to the Section Omics/Informatics)
Personalized Innovations in Integrated Breast Cancer Management
edited by
submission deadline 28 Feb 2026 | Viewed by 102 | Submission Open
Keywords: personalized breast cancer treatment; breast surgery innovation; multidisciplinary cancer care; precision medicine; patient-centered oncology; minimally invasive breast surgery; advanced oncoplastic techniques; genomic-driven surgical planning
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Approaches in Bladder Cancer Treatment: A Clinical and Translational Research Perspective
edited by
submission deadline 28 Feb 2026 | Viewed by 53 | Submission Open
Keywords: bladder cancer (BC); systemic therapy; tailored therapy; immune checkpoint inhibitors; antibody– drug conjugates (ADCs); molecular targeted therapy
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Diagnosis and Treatment of Hematological Malignancies
edited by Adam S. Zayac
submission deadline 28 Feb 2026 | Viewed by 29 | Submission Open
Keywords: hematologic malignancies; targeted therapies; myeloid neoplasms; non-hodgkin lymphoma; plasma cell neoplasms; supportive care; immunotherapies; cellular therapies
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
The Ethnoracial Diversity of Diabetes: Insights into Epidemiology, Genetics, Disease Management, and Personalized Therapies
edited by
submission deadline 5 Mar 2026 | Viewed by 570 | Submission Open
Keywords: diabetes disparities; ethnoracial diversity; genetic epidemiology; personalized therapy; health equity
(This special issue belongs to the Section Epidemiology)
Novel and Personalized Treatment Concepts in Gynecologic Cancer—2nd Edition
edited by and
submission deadline 10 Mar 2026 | Viewed by 319 | Submission Open
Keywords: ovarian cancer; endometrial cancer; vulvar cancer; cervical cancer; homologous recombination; targeted therapy; DNA damage repair; biomarkers; imaging; individualized treatment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advanced Imaging and Artificial Intelligence in Personalized Medicine: Innovations and Future Directions submission deadline 10 Mar 2026 | Viewed by 75 | Submission Open
Keywords: precision imaging; personalized medicine; radiomics; molecular imaging; artificial intelligence; imaging biomarkers; theranostics; multi-omics integration; predictive modeling; translational research
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
From Biomarkers to Breakthroughs: Advancing Lung Cancer Research submission deadline 15 Mar 2026 | Viewed by 13 | Submission Open
Keywords: lung cancer; biomarkers; personalized medicine; molecular diagnostics; targeted therapy; non-small cell lung cancer; small cell lung cancer; resistance mechanisms; translational research; precision oncology
(This special issue belongs to the Section Disease Biomarker)
Personalized Medicine of Obesity and Metabolic Disorders
edited by , and Cătălina Poiană
submission deadline 20 Mar 2026 | 2 articles | Viewed by 1690 | Submission Open
Keywords: obesity; childhood obesity; metabolic disorders; leptin; adipogenesis; adipokines; dietary intake; physical activity; behavior; obesity-related diseases; metabolic dysfunction-associated steatotic liver disease (MASLD)
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Latest Advances and Challenges in Bariatric Surgery submission deadline 20 Mar 2026 | Viewed by 429 | Submission Open
Keywords: bariatric surgery; gut microbiota; inflammation; type 2 diabetes mellitus; metabolic syndrome; post-surgical comorbidities; obesity management; metabolic alterations; surgical outcomes; morbid obesity
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Urological Cancer: Clinical Advances in Personalized Therapy
edited by and Marco Paciotti
submission deadline 25 Mar 2026 | 2 articles | Viewed by 2363 | Submission Open
Keywords: minimally invasive surgery; robot-assisted surgery; immunotherapy; prostate cancer; renal cancer; urothelial cancer
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Clinical Updates on Personalized Upper Gastrointestinal Surgery
edited by Dimitrios Kehagias
submission deadline 25 Mar 2026 | Viewed by 799 | Submission Open
Keywords: upper gastrointestinal tract; minimally invasive surgery; anti-reflux surgery; hiatal hernia; achalasia; oesophagogastric resection; personalized treatment; fluorescence guided upper gastrointestinal surgery; anastomotic leakage and perforation of the upper gastrointestinal tract; benign and malignant esophageal diseases; benign and malignant gastric diseases
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Cardiothoracic Surgery: Treatment and Management
edited by
submission deadline 25 Mar 2026 | Viewed by 245 | Submission Open
Keywords: lung cancer; mediastinum; VATS; RATS; cardiothoracic surgery; new technologies; thoracic anesthesia; regional anesthesia
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Current Trends and Future Challenges in Hepatocellular Carcinoma
edited by
submission deadline 25 Mar 2026 | Viewed by 219 | Submission Open
Keywords: HCC; MASLD; viral hepatitis; HCC heterogenity; biomarker; therapeutic targeting; personalized medicine; immune therapy
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Emerging Trends in Diagnostic and Interventional Radiology: Towards Personalized Medicine
edited by
submission deadline 25 Mar 2026 | Viewed by 107 | Submission Open
Keywords: CT; MRI; interventional radiology; personalized medicine; artificial intelligence; radiomics
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
New Technologies and Personalized Medicine in Gastrointestinal Surgery
edited by
submission deadline 25 Mar 2026 | Viewed by 75 | Submission Open
Keywords: new technologies; robotic surgery; surgical innovation; AI in surgery; new materials in surgery; minimally invasive surgery; personalized medicine; theranostics in gastrointestinale cancer
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Diagnosis and Treatment of Heart Failure submission deadline 25 Mar 2026 | Viewed by 28 | Submission Open
Keywords: heart failure; acute heart failure; personalized medicine; comorbidities; cardiac electrophysiology; cardiology
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Tailored Strategies in Abdominal Surgery submission deadline 25 Mar 2026 | Viewed by 17 | Submission Open
Keywords: personalized surgery; abdominal surgery; pancreatic cancer; colorectal cancer; hepatobiliary surgery; laparoscopic and robotic surgery; surgical oncology; precision medicine
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Diabetes Mellitus: Current Research and Future Perspectives, 2nd Edition
edited by
submission deadline 30 Mar 2026 | 4 articles | Viewed by 8472 | Submission Open
Keywords: diabetes treatment; drug metabolism; disease complications; polymorphisms; epigenetics; metabolomics; proteomics
(This special issue belongs to the Section Mechanisms of Diseases)
New Insights into Personalized Medicine for Cardiac Surgery: Clinical Advances in Diagnosis, Treatment, and Prognosis
edited by and Anja Osswald
submission deadline 30 Mar 2026 | 1 articles | Viewed by 1241 | Submission Open
Keywords: cardiovascular disease; patient-centered care; personalized medicine; interdisciplinary approaches; artificial intelligence; prognostic tools; minimally invasive surgery; robotic surgery; bioengineering; cardiovascular genomics
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Diagnostics and Therapeutics in Ophthalmology—2nd Edition
edited by
submission deadline 31 Mar 2026 | 4 articles | Viewed by 4192 | Submission Open
Keywords: ophthalmology; retina; myopia; glaucoma; cataract; clinical studies; systematic reviews; meta-analyses
(This special issue belongs to the Section Evidence Based Medicine)
Personalized Management in Chronic Obstructive Pulmonary Disease (COPD)
edited by Paolo Ruggeri
submission deadline 31 Mar 2026 | Viewed by 215 | Submission Open
Keywords: COPD; lung function; comorbidities; cardiopulmonary risk; exacerbation; inhalation therapy; early diagnosis; phenotyping
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Treatment for Cardiac Surgery: Updates and Challenges
edited by Giacomo Bortolussi and
submission deadline 31 Mar 2026 | Viewed by 210 | Submission Open
Keywords: cardiac surgery; coronary artery bypass grafting; transcatheter aortic valve replacement; mitral valve repair; heart transplant; sternotomy; wound care; gender
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
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