Special Issues

Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Precision Medicine in the Intensive Care Unit
edited by Carmen Orban and
submission deadline 10 May 2025 | 1 articles | Viewed by 1624 | Submission Open
Keywords: critical care; phenotypes in the intensive care unit; personalized medicine; patient-centered management; organ dysfunction; organ support; advanced monitoring; diagnostics
(This special issue belongs to the Section Personalized Critical Care)
Current Trends in Cataract Surgery
edited by Romina Fasciani and
submission deadline 15 May 2025 | 2 articles | Viewed by 2322 | Submission Open
Keywords: refractive cataract surgery; visual quality; dry eye; side effects; advanced technology intraocular lenses; AMD IOLs
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Diagnosis and Personalized Therapy in Chronic Upper Aerodigestive Tract Disorders
edited by Maria Raffaella Marchese
submission deadline 15 May 2025 | 1 articles | Viewed by 2294 | Submission Open
Keywords: upper aerodigestive tract; swallowing; voice; rhinitis; sinonasal diseases; dysphonia; tonsillitis; peritonsillar abscess; OSAS; laryngopharyngeal reflux
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
New Trends and Challenges in Digital Dentistry
edited by and Flares Baratto-Filho
submission deadline 15 May 2025 | Viewed by 258 | Submission Open
Keywords: dental research; tomography; radiograph; artificial inteligence; machine learning; digital dentistry
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Tailoring Treatment with Biomarkers: Advancements in Heart Failure Management submission deadline 16 May 2025 | 2 articles | Viewed by 3901 | Submission Open
Keywords: biomarkers; heart failure; precision cardiology; risk prediction; outcomes; treatment
(This special issue belongs to the Section Disease Biomarker)
Diabetes Mellitus: Current Research and Future Perspectives, 2nd Edition
edited by
submission deadline 20 May 2025 | 4 articles | Viewed by 7092 | Submission Open
Keywords: diabetes treatment; drug metabolism; disease complications; polymorphisms; epigenetics; metabolomics; proteomics
(This special issue belongs to the Section Mechanisms of Diseases)
Breast Cancer: Current Trends and Future Challenges in Evaluation and Treatment
edited by Stefano Spinaci and Giulia Ferrarazzo
submission deadline 20 May 2025 | 3 articles | Viewed by 3495 | Submission Open
Keywords: breast cancer; breast surgery; conservative surgery; robotic breast techniques; male breast cancer
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Therapeutics and Drug Development of Liver Disease submission deadline 20 May 2025 | Viewed by 193 | Submission Open
Keywords: precision medicine; hepatocellular carcinoma (hcc); non-alcoholic fatty liver disease (nafld); metabolic dysfunction-associated steatotic liver disease (masld); liver fibrosis; biomarkers; targeted therapy; drug development; pharmacogenomics; immunotherapy; molecular pathways; genomic profiling; personalized treatment; translational research; clinical trials; novel therapeutics; liver disease management; drug delivery systems
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Sex and Gender-Related Issues in the Era of Personalized Medicine
edited by , Anna Maria Moretti and Biagio Moretti
submission deadline 22 May 2025 | 7 articles | Viewed by 12928 | Submission Open
Keywords: gender; sex differences; sex factors; personalized medicine; cardiovascular disease; hypertension; obesity; diabetes; psychiatry and psychology; public health and epidemiology; women’ s health; sex; osteoporosis; osteoarthritis; musculoskeletal diseases
(This special issue belongs to the Section Sex, Gender and Hormone Based Medicine)
Innovations in Personalized Diagnosis and Treatment for Cystic Fibrosis
edited by
submission deadline 22 May 2025 | Viewed by 319 | Submission Open
Keywords: cystic fibrosis; CFTR mutations; modulators; biomarkers; treatment strategies; theratyping; genotype– phenotype correlation; pharmacogenomics; gene therapy; disease modeling; precision medicine; personalized diagnostics and therapies
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Emergency Medicine: Clinical Advances and Challenges in Diagnosis and Treatment, 2nd Edition submission deadline 25 May 2025 | 10 articles | Viewed by 19612 | Submission Open
Keywords: shock and resuscitation; sepsis; learning; critical patient approach; medical education; challenging diagnosis; treatment advances; use of simulation in medical training; emergency department digitalization; interesting cases in emergency medicine; diagnostic and therapeutic protocols in emergency medicine
(This special issue belongs to the Section Personalized Critical Care)
Personalized Medicine for Autism Spectrum Disorder
edited by
submission deadline 25 May 2025 | 1 articles | Viewed by 10071 | Submission Open
Keywords: autism spectrum disorder; comorbidity; personalized medicine; environmental factors; diagnosis; classification; treatment; management
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Precision Medicine in Vascular Disease
edited by Gaetano Lanza and Carlo Setacci
submission deadline 25 May 2025 | 4 articles | Viewed by 7058 | Submission Open
Keywords: precision medicine; vascular diseases; pathogenetics; diagnostics; genetics; omics; biomarkers; predictive factors; medical therapies; surgical indications
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Clinical Advances in Dermatology: Pathophysiology, Diagnosis and Treatment
edited by and Manuel Galán-Gutiérrez
submission deadline 25 May 2025 | 3 articles | Viewed by 5038 | Submission Open
Keywords: psoriasis; atopic dermatitis; laser therapy; urticaria; alopecia areata; treatment; biological treatment; JAK (Janus Kinase) inhibitors
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
The Gut Microbiome as a Target for the Treatment of Inflammatory Bowel Diseases
edited by and
submission deadline 25 May 2025 | 1 articles | Viewed by 4321 | Submission Open
Keywords: inflammatory bowel diseases (IBD); gut microbiome; microbial dysbiosis; Crohn's disease; ulcerative colitis; microbiota; microbiome– host interactions; immune response; microbial metabolites; fecal microbiota transplantation (FMT); probiotics; prebiotics; postbiotics; precision medicine; personalized therapy; microbial biomarkers; microbiome-based interventions; microbiome modulation; mucosal healing; gut– brain axis; microbiome analysis techniques; clinical trials; translational research; microbial engineering; therapeutic targets; metabolomics
(This special issue belongs to the Section Disease Biomarker)
Urological Cancer: Clinical Advances in Personalized Therapy
edited by and Marco Paciotti
submission deadline 25 May 2025 | 1 articles | Viewed by 1921 | Submission Open
Keywords: minimally invasive surgery; robot-assisted surgery; immunotherapy; prostate cancer; renal cancer; urothelial cancer
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Precision Medicine in Cardiovascular Disease
edited by
submission deadline 25 May 2025 | Viewed by 594 | Submission Open
Keywords: cardiovascular disease; personalized medicine  ; genomics; risk prediction  ; precision therapy  ; AI; telediagnostics  ; telemedicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Innovations in Cancer Immunology: Personalized Therapeutic Approaches
edited by
submission deadline 25 May 2025 | 1 articles | Viewed by 514 | Submission Open
Keywords: cancer immunology; personalized therapies; immunotherapy; CAR-T cell therapy; tumor microenvironment; biomarkers; patient selection; treatment resistance; combination therapies
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Pediatric Neurology: Current Trends, Rehabilitation and Future Challenges, 2nd Edition
edited by
submission deadline 25 May 2025 | Viewed by 501 | Submission Open
Keywords: neurodevelopmental disorders; cerebral palsy; autism; assessment; sleep
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Novel Biomarkers and Personalized Diagnosis in Neurodegenerative Disease
edited by Edoardo Gioele Spinelli
submission deadline 25 May 2025 | Viewed by 463 | Submission Open
Keywords: Alzheimer’ s disease; dementia; amyotrophic lateral sclerosis; Parkinson’ s disease; neurodegeneration; neuroimaging; MRI; biomarkers; artificial intelligence; machine learning
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Medicine of Obesity and Metabolic Disorders
edited by , and Cătălina Poiană
submission deadline 25 May 2025 | Viewed by 319 | Submission Open
Keywords: obesity; childhood obesity; metabolic disorders; leptin; adipogenesis; adipokines; dietary intake; physical activity; behavior; obesity-related diseases; metabolic dysfunction-associated steatotic liver disease (MASLD)
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Diagnostic and Interventional Radiology: Opportunities and Challenges of Advanced Imaging Techniques
edited by Leona S. Alizadeh and Boris Bodelle
submission deadline 25 May 2025 | Viewed by 275 | Submission Open
Keywords: advanced imaging techniques; diagnostic radiology; interventional radiology; personalized medicine; precision diagnosis; minimally invasive procedures; image-guided therapy; artificial intelligence in radiology; cardiovascular imaging; oncology imaging
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Cancer Immunology: New Advances in Personalized Therapies
edited by John Victor Napoleon
submission deadline 25 May 2025 | Viewed by 264 | Submission Open
Keywords: personalized therapy; immune system modulation; drugs and pharmaceutics; checkpoint inhibitor therapy; cancer immunotherapy; targeted drug delivery; tumor microenvironment; treatment resistance; combination therapy
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Novel Therapeutic Approaches in Oral and Maxillofacial Surgery
edited by Krzysztof Dowgierd
submission deadline 25 May 2025 | Viewed by 193 | Submission Open
Keywords: craniofacial deformities; craniofacial reconstruction; cleft lip and palate; craniofacial biology; maxillofacial surgery
(This special issue belongs to the Section Mechanisms of Diseases)
Brain Tumor Microenvironment and Host Role: Implications for Immunotherapy
edited by Susobhan Sarkar
submission deadline 25 May 2025 | Viewed by 157 | Submission Open
Keywords: brain metastasis; brain tumor; glioma; microenvironment; microglia; immunotherapy; tumor microenvironment
(This special issue belongs to the Section Mechanisms of Diseases)
Advancements in Cognitive Neurosciences for Personalized Medicine
edited by Antonio Gennaro Nicotera
submission deadline 30 May 2025 | 3 articles | Viewed by 5128 | Submission Open
Keywords: cognitive neuroscience; pediatric neurology; neuropsychology; neurogenetic; neurocomputation; autism; epilepsy
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Selected Papers From the pHealth 2024 Conference, Rende, Italy, 27–29 May 2024
edited by , and Pierangelo Veltri
submission deadline 30 May 2025 | 1 articles | Viewed by 1361 | Submission Open
Keywords: 5P medicine; transformed health ecosystems; systems integration and interoperability; knowledge representation and management
(This special issue belongs to the Section Omics/Informatics)
New Insights into Personalized Medicine for Cardiac Surgery: Clinical Advances in Diagnosis, Treatment, and Prognosis
edited by and Anja Osswald
submission deadline 30 May 2025 | 1 articles | Viewed by 928 | Submission Open
Keywords: cardiovascular disease; patient-centered care; personalized medicine; interdisciplinary approaches; artificial intelligence; prognostic tools; minimally invasive surgery; robotic surgery; bioengineering; cardiovascular genomics
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Machine Learning in Epidemiology
edited by Xingyu Zhang and
submission deadline 30 May 2025 | Viewed by 441 | Submission Open
Keywords: artificial intelligence; machine learning; epidemiology; predictive analytics; health data; public health; precision medicine; disease surveillance; big data analytics
(This special issue belongs to the Section Epidemiology)
Cardiology and Vascular Health: Pathophysiology, Therapeutics and Epidemiology submission deadline 31 May 2025 | 5 articles | Viewed by 13236 | Submission Open
Keywords: cardiovascular disease; peripheral arterial disease; coronary heart disease; heart failure; cerebrovascular diesease; diabetes mellitus; dyslipidemia; arterial hypertension; arterial stiffness; endothelial dysfunction
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Challenges and Opportunities in Personalized Management of Bone and Joint Infections submission deadline 31 May 2025 | 1 articles | Viewed by 2442 | Submission Open
Keywords: bone and joint infections; prosthetic joint infection; arthroplasty infection; definition of prosthetic joint infection; prosthetic joint infection prevention; diagnosis of prosthetic joint infection; prosthetic joint infection management; antimicrobial therapy of prosthetic joint infection; diagnostics and management of septic arthritis in native joints; future research directions for improved patient outcomes
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
New Advances in Metabolic Diseases Diagnostics and Treatment: From Basic Research to Clinical Practice submission deadline 31 May 2025 | 1 articles | Viewed by 2266 | Submission Open
Keywords: metabolic disease; inherited metabolic disease; mitochondrial metabolism; metabolomics; multi-omics; biomarkers
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Diagnostics and Therapeutics in Ophthalmology—2nd Edition
edited by
submission deadline 31 May 2025 | 4 articles | Viewed by 1587 | Submission Open
Keywords: ophthalmology; retina; myopia; glaucoma; cataract; clinical studies; systematic reviews; meta-analyses
(This special issue belongs to the Section Evidence Based Medicine)
Precision Medicine in Urologic Oncology
edited by Orsolya Martha and Calin Chibelean
submission deadline 31 May 2025 | Viewed by 563 | Submission Open
Keywords: urodynamics; urooncology; reconstruction; LUTS; functional urology
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Current Status and Future Research in Infectious Diseases’ Treatment and Prophylaxis submission deadline 31 May 2025 | Viewed by 522 | Submission Open
Keywords: infectious diseases; current status of infectious diseases; future research on infectious diseases; prophylaxis of infectious diseases; treatment of infectious diseases
(This special issue belongs to the Section Epidemiology)
Interventional Cardiology: Advances in Personalized Treatment and Management submission deadline 31 May 2025 | Viewed by 225 | Submission Open
Keywords: interventional cardiology; ischaemic disease; cardiovascular diseases; coronary artery disease; percutaneous coronary intervention; structural heart disease; transcatheter; minimally invasive; intravascular imaging; vascular access; pharmacological treatment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Management in Chronic Obstructive Pulmonary Disease (COPD)
edited by Paolo Ruggeri
submission deadline 31 May 2025 | Viewed by 184 | Submission Open
Keywords: COPD; lung function; comorbidities; cardiopulmonary risk; exacerbation; inhalation therapy; early diagnosis; phenotyping
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Treatment for Cardiac Surgery: Updates and Challenges
edited by Giacomo Bortolussi and
submission deadline 31 May 2025 | Viewed by 184 | Submission Open
Keywords: cardiac surgery; coronary artery bypass grafting; transcatheter aortic valve replacement; mitral valve repair; heart transplant; sternotomy; wound care; gender
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine in Otolaryngology—Head and Neck Surgery: Updates and Challenges
edited by Itzhak Braverman
submission deadline 31 May 2025 | Viewed by 160 | Submission Open
Keywords: OSA; rhinology; voice; oncology; personalized ENT surgery; facial palsy; head and neck oncology
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advances in Therapeutic Strategies for Gastrointestinal Diseases and Diabetes
edited by and Seeun Ha
submission deadline 31 May 2025 | Viewed by 147 | Submission Open
Keywords: diabetes; gastrointestinal disease; diabetic gastroparesis; diabetic enteropathy; diabetes medication; gastrointestinal medication
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Prospectives in Regenerative Medicine and Surgery: Stem Cells and Beyond
edited by Francesca Toia and Gabriele Storti
submission deadline 10 Jun 2025 | 1 articles | Viewed by 1941 | Submission Open
Keywords: regenerative medicine; regenerative surgery; adipose-derived stem cells (ASCs); mesenchymal stem cells (MSCs); tissue engineering; extracellular vesicles (EVs); microvesicles (MVs)
(This special issue belongs to the Section Regenerative Medicine and Therapeutics)
Current Trends and Future Challenges in Hepatocellular Carcinoma
edited by
submission deadline 10 Jun 2025 | Viewed by 183 | Submission Open
Keywords: HCC; MASLD; viral hepatitis; HCC heterogenity; biomarker; therapeutic targeting; personalized medicine; immune therapy
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Clinical Updates on Reproductive Medicine submission deadline 15 Jun 2025 | 1 articles | Viewed by 6838 | Submission Open
Keywords: reproductive medicine; assisted reproductive technology; infertility; embryology; immunology; reproductive surgery; artificial intelligence; reproductive surgery; fertility preservation; fertility counseling
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Novel Biomarkers in the Diagnostics of Cancer submission deadline 15 Jun 2025 | 3 articles | Viewed by 6633 | Submission Open
Keywords: cancer biomarkers; liquid biopsy; circulating tumor DNA; exosomes; cancer personalized medicine; biomarker validation; genomic biomarkers; epigenetic markers; proteomic signatures; metabolomic profiling
(This special issue belongs to the Section Disease Biomarker)
Personalized Diagnosis and Treatment for Obstructive Sleep Apnea
edited by Amro Daboul
submission deadline 15 Jun 2025 | 1 articles | Viewed by 2514 | Submission Open
Keywords: personalized sleep medicine; OSA phenotypic traits; patient-centered sleep diagnostics; customized diagnostic algorithms; genetic markers in OSA diagnosis; customized therapeutic approaches; emerging OSA therapies
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Congenital Heart Defects: Diagnosis and Personalized Treatment
edited by Bhaswati Roy
submission deadline 15 Jun 2025 | Viewed by 222 | Submission Open
Keywords: congenital heart defects; congenital heart disease; cardiology; heart failure
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Interventional Radiology: Towards Personalized Medicine
edited by
submission deadline 20 Jun 2025 | 7 articles | Viewed by 16093 | Submission Open
Keywords: interventional radiology; trauma management; interventional radiology tailored to patients; interventional oncology; diagnostic and interventional radiology; image-guided biopsy
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Medicine in Post-COVID-19 Era submission deadline 20 Jun 2025 | 3 articles | Viewed by 6883 | Submission Open
Keywords: long COVID management; vaccine development; risk assessment; rehabilitation; public health approach; laboratory diagnosis; drug development and repurposing; genetic factor; proteomics; genomics
(This special issue belongs to the Section Epidemiology)
The Development of Echocardiography in Heart Disease
edited by Jolanta Justina Vaskelyte, Egle Rumbinaite and Vaida Mizariene
submission deadline 20 Jun 2025 | 3 articles | Viewed by 6012 | Submission Open
Keywords: echocardiography; speckle tracking; CAD; valvular pathology; myocardial/pericardial diseases; congenital defects; rare cardiac diseases; interventional procedures
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Hormone Therapies for Women submission deadline 20 Jun 2025 | 2 articles | Viewed by 5696 | Submission Open
Keywords: reproductive medicine; hormone therapy; PCOS; gender medicine; contraception; medico-legal implications; inositol therapy; fertility preservation; psychological factors
(This special issue belongs to the Section Sex, Gender and Hormone Based Medicine)
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