Novel Challenges and Advances in Neuro-Oncology

Dear Colleagues,

The neuro-oncology field has witnessed significant developments in recent years. New perioperative mapping techniques improved our understanding about the human brain. The advances in basic sciences further enlightened the tumour–brain interactions, providing rational tools to adapt personalized surgical resections. Intraoperative diagnostics empower surgical teams to establish risk-benefit decision flowcharts when tailoring patient-centred extent of resections. Emerging rehabilitation programs centred on patient-specific brain stimulation improve motor and cognitive outcomes, improving quality of life and reducing time-to-adjuvant treatment when required. Adjuvant treatments beyond surgery have diversified and significantly improved oncological and functional outcomes, being responsible for a true revolution in the field.

However, as we move on with diagnostics and treatments, new challenges arise that were previously unforeseen. Improving targeted sampling and focused treatments with fewer side effects for patients remains the target, and this is being pushed forward by the mentioned recent advances. Aiming for disease control and cure is probably not yet on the horizon for most of the conditions in neuro-oncology, but they remain goals to achieve, and small steps will lead the way.

This launches this necessary topic focused on “Novel Challenges and Advances in Neuro-Oncology”. We invite you to submit your work to this topic so we can contribute and summarize recent developments in the field and help to pave the way for future advances.

Prof. Dr. Keyoumars Ashkan
Dr. José Pedro Lavrador
Guest Editors

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