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Advances in Plastic and Reconstructive and Aesthetic Surgery of Face, Breast and Body

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Dear Colleagues,

As the guest editor for this Special Issue of our esteemed journal, we invite contributions that explore the multifaceted landscape of plastic and reconstructive surgery. This issue aims to highlight advancements in reconstructive techniques, with a particular focus on reconstructive and breast surgery, which remain a pivotal area of innovation and clinical practice. We encourage submissions that present novel academic research, including clinical trials, systematic reviews, and meta-analyses that contribute to the evidence base in plastic surgery.

Additionally, we seek to examine the intersection of social media and plastic surgery, an increasingly relevant topic in contemporary practice. Articles that investigate the impact of social media on patient perceptions, decision-making, and the dissemination of information within the field are particularly welcome. We believe that this Special Issue will not only showcase cutting-edge research and innovations but also foster a dialogue on the evolving role of digital platforms in shaping the future of plastic and reconstructive surgery. We look forward to your valuable contributions that will enrich this important discourse.

Dr. Valentin Haug
Guest Editor

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21 pages, 12169 KiB

Open AccessArticle

“Ozempic Face”: An Emerging Drug-Related Aesthetic Concern and Its Treatment with Endotissutal Bipolar Radiofrequency (RF)—Our Experience

by Luciano Catalfamo, Francesco Saverio De Ponte and Danilo De Rinaldis

J. Clin. Med. 2025, 14(15), 5269; https://doi.org/10.3390/jcm14155269 - 25 Jul 2025

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Abstract

Background/Objectives: “Ozempic face” is an aesthetic side effect associated with the use of the antidiabetic agent Ozempic (semaglutide), characterized by a prematurely aged and fatigued facial appearance due to rapid weight loss. Currently, treatment options for this condition are limited. In this study, we present our clinical experience with the BodyTite device, provided by InMode Italy S.r.l. (Rome, Italy). Materials and Methods: We report a case series involving 24 patients (19 women and 5 men, aged 27–65 years), treated with subdermal bipolar radiofrequency (Endotissutal Bipolar Radiofrequency) between 2023 and 2024. All patients underwent a minimum follow-up of 12 months. At the end of the follow-up period, patients rated their satisfaction on a from 0 to 10 scale, and an independent expert assessed the stability of clinical outcomes. Results: The majority of patients reported high satisfaction levels (≥8), which correlated with the independent expert’s evaluation of treatment efficacy and result stability. The only observed adverse event was transient cutaneous erythema. Conclusions: “Ozempic face” is an increasingly common side effect associated with newer classes of antidiabetic medications. Although these drugs offer significant metabolic benefits, the accompanying facial volume loss and aging are often poorly tolerated by patients. Our findings suggest that subdermal bipolar radiofrequency represents a safe, low-risk, and cost-effective therapeutic option for the aesthetic management of Ozempic face. Full article

(This article belongs to the Special Issue Advances in Plastic and Reconstructive and Aesthetic Surgery of Face, Breast and Body)

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12 pages, 1234 KiB

Open AccessArticle

Establishment of Norms for Facial Discriminative Sensitivity in Healthy Women Aged 45–60 Years: A Reference Framework

by François-Régis Sarhan, Thomas Davergne, Christine Couturaud, Sylvie Testelin and Stéphanie Dakpé

J. Clin. Med. 2025, 14(14), 4884; https://doi.org/10.3390/jcm14144884 - 9 Jul 2025

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Abstract

Background/Objectives: In the context of facial surgery, particularly reconstructive procedures, sensory recovery is a critical yet often underexplored aspect of functional rehabilitation. Sensory-motor recovery can be considered a key marker of integration following reconstructive surgery. Among sensory modalities, discriminative sensitivity is typically the last to recover, making its evaluation particularly relevant. While established norms for hand sensitivity exist in the literature, there is a paucity of data regarding facial sensitivity. The objective of this study was to evaluate the discriminative sensitivity of the face in a population of healthy women aged 45–60 years. Methods: A total of 20 healthy women were included between January and March 2013. Participants had no history of facial pathologies or trauma. Discriminative sensitivity was measured using the Disk-Criminator™ device across eight facial zones. A detailed mapping of the tested areas was performed. Data obtained were compared with the existing literature. Statistical analyses included Shapiro–Wilk tests for normality, followed by Student’s t-tests for group comparisons. To account for small sample size and verify robustness, non-parametric Mann–Whitney U tests were also performed. Adjustment for multiple comparisons was applied using the Bonferroni correction (adjusted α = 0.0125). Results: The mean age of participants was 52.3 years (±4.0 years). Discrimination threshold values ranged from 2.9 to 14.3 mm. Comparison with existing studies showed no significant age-related differences in zone 2R (cheek) and zone 8 (lower lip), suggesting stable sensitivity in these regions across adulthood. However, a significant decline in sensitivity with age was observed only in zone 1R (forehead), with a p-value < 0.001 after Bonferroni correction. Conclusions: We established a reference framework for cutaneous discriminative sensitivity across eight facial zones. These norms can serve as a baseline for the assessment and monitoring of patients with facial pathologies. Furthermore, our findings contribute to a better understanding of age-related sensory changes. Full article

(This article belongs to the Special Issue Advances in Plastic and Reconstructive and Aesthetic Surgery of Face, Breast and Body)

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