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Hepatobiliary–Pancreatic Surgery in the Era of Interventional Radiology
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Hepatobiliary–Pancreatic Surgery in the Era of Interventional Radiology

A Special Issue of Journal of Clinical Medicine (ISSN 2077-0383) belonging to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: 20 April 2027 | Viewed by 750

Editor

Dr. Dimitrios Giannis

E-Mail Website
Guest Editor
Department of Surgery, Flushing Hospital Medical Center, MediSys Health Network, Flushing, Queens, NY 11355, USA
Interests: interventional radiology; percutaneous cholecystostomy; minimally invasive hepatobiliary surgery; cryoablation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Hepatobiliary–pancreatic (HBP) surgery continues to face challenges in managing complex biliary and pancreatic disease, including high-risk malignancies, strictures, severe cholecystitis, cholangitis, and associated postoperative complications. Despite advances in operative techniques, perioperative morbidity and treatment limitations remain significant. Interventional radiology (IR) has emerged as a critical adjunct, offering minimally invasive solutions such as percutaneous biliary and pancreatic drainage, portal vein embolization, tumor ablation, and endovascular interventions. These techniques optimize surgical candidacy, reduce operative risk, and expand treatment options for high-risk surgical candidates.

This Special Issue aims to highlight innovations in HBP surgery supported by interventional radiology, addressing key clinical and technical challenges, improving perioperative outcomes, and advancing multidisciplinary care. We welcome authors to submit original research and review articles that demonstrate IR-driven strategies to enhance surgical planning, outcomes, and patient safety.

By focusing on IR integration, this Special Issue seeks to advance knowledge, refine surgical practice, and shape the future of hepatobiliary–pancreatic care.

Dr. Dimitrios Giannis
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hepato-biliary–pancreatic surgery
  • interventional radiology
  • percutaneous biliary drainage
  • percutaneous pancre-atic drainage
  • portal vein embolization
  • tumor ablation
  • minimally invasive surgery
  • cryoablation
  • thermoablation

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Published Papers (1 paper)

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Review

15 pages, 612 KB  
Review
Interventional Radiology in Acute Cholecystitis: A Review of Contemporary Percutaneous Strategies and Emerging Techniques
by Dimitrios Giannis and Panagiota Gianni
J. Clin. Med. 2026, 15(13), 5106; https://doi.org/10.3390/jcm15135106 - 30 Jun 2026
Viewed by 383
Abstract
Background/Objectives: Acute cholecystitis is a common surgical emergency associated with significant morbidity in elderly, frail, and critically ill poor surgical candidates. Early laparoscopic cholecystectomy remains the standard of care for low-risk patients, but interventional radiology (IR) modalities have been increasingly used in [...] Read more.
Background/Objectives: Acute cholecystitis is a common surgical emergency associated with significant morbidity in elderly, frail, and critically ill poor surgical candidates. Early laparoscopic cholecystectomy remains the standard of care for low-risk patients, but interventional radiology (IR) modalities have been increasingly used in high-risk patients for gallbladder decompression, source control, and/or definitive non-operative treatment. Methods: A narrative review of the literature was performed to investigate current percutaneous IR options in acute cholecystitis. Evidence from international guidelines, randomized trials, systematic reviews, meta-analyses, and experimental novel techniques were reviewed. The patient selection approaches, timing of intervention, efficacy, complications, and risk of recurrence were summarized. Results: Percutaneous cholecystostomy remains the most commonly performed IR procedure for acute cholecystitis, offering decompression and source control in patients unfit for surgery. Percutaneous gallstone extraction and gallbladder chemical ablation, or cryoablation, have been used to reduce recurrence and long-term catheter dependence with promising results, but are still limited by complications and insufficient evidence. The variability in practice patterns and the absence of standardized treatment algorithms contribute to mixed results, ranging from long-term/definitive symptom control to the prolonged dependence on indwelling catheters and readmissions for catheter-related complications. Conclusions: IR plays an important role in the management of high-risk patients with acute cholecystitis. The careful selection of patients based on disease severity, physiologic reserve, frailty, and patient-centered goals is frequently limited by institutional resources. A structured clinical decision framework to guide IR-based interventions in acute cholecystitis is of the utmost importance to achieve optimal outcomes. Future studies should focus on standardized algorithms, patient-centered outcomes, recurrence, tube-free survival, and quality of life. Full article
(This article belongs to the Special Issue Hepatobiliary–Pancreatic Surgery in the Era of Interventional Radiology)
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