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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Plastic and Reconstructive and Aesthetic Surgery of Face, Breast and Body

edited by

Valentin Haug

submission deadline 24 Aug 2026 | 6 articles | Viewed by 20759

Keywords: reconstructive surgery; academic plastic surgery; research; social media in plastic surgery; breast surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Advancements in Cardiomyopathies: Diagnosis, Treatment and Management—2nd Edition

edited by

Cinzia Forleo

and

Maria Cristina Carella

submission deadline 24 Aug 2026 | 5 articles | Viewed by 11805

Keywords: cardiomyopathies; multimodality imaging; cardiac magnetic resonance; genetic testing; cardiogenetics; genetic cardiovascular disease; rare cardiovascular diseases; risk stratification; genotype–phenotype correlations; rare variant interpretation; arrhythmias

(This special issue belongs to the Section Cardiology)

Clinical Advances in Head and Neck Cancer Diagnostics and Treatment

edited by

Dustin A. Silverman

and Alice L. Tang

submission deadline 24 Aug 2026 | 1 articles | Viewed by 1653

Keywords: head and neck; reconstruction; free flap; surgical margin; biomarker; human papillomavirus (HPV); extranodal extension; immunotherapy; virtual surgical planning

(This special issue belongs to the Section Otolaryngology)

Interventional and Surgical Treatment of Acute and Chronic Pancreatitis

edited by Chirag Desai

submission deadline 25 Aug 2026 | 6 articles | Viewed by 22700 | Submission Open

Keywords: pancreatitis treatment; endoscopic treatment; pancreatic surgery; Whipple; distal pancreatectomy; islet cell auto trans-plant; total pancreatectomy; TPIAT; laparoscopic treatment of pancreatitis; robotic surgery for pancreatitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Alcohol-Related Liver Disease: Diagnosis, Treatment, and Management

edited by

Adrian Boicean

and

Cristian Ichim

submission deadline 25 Aug 2026 | 5 articles | Viewed by 16851 | Submission Open

Keywords: alcohol-related liver disease; gut–liver axis; hepatic fibrosis; liver cirrhosis; micro-RNA; inflammatory pathways; liver transplantation; steatohepatitis; fecal microbiota transplantation in liver cirrhosis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Periodontal Diseases and Systemic Health: Pathogenesis, Prevention and Management

edited by

Saverio Cosola

submission deadline 25 Aug 2026 | 8 articles | Viewed by 13011 | Submission Open

Keywords: periodontitis; dental implants; systemic inflammation; diabetes and periodontal disease; cardiovascular implications; pregnancy and oral health; host immune responses; preventive dentistry; implant-prosthetic rehabilitation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in the Management of Cardiac Amyloidosis and Hypertrophic Cardiomyopathy

edited by Ahmed Abuzaid

submission deadline 25 Aug 2026 | 5 articles | Viewed by 10619 | Submission Open

Keywords: cardiac amyloidosis; hypertrophic cardiomyopathy; left ventricular hypertrophy; non-invasive cardiac imaging; heart failure; clinical manifestations

(This special issue belongs to the Section Cardiology)

New Insights into Cardiorenal Metabolic Syndrome

edited by

Caterina Carollo

submission deadline 25 Aug 2026 | 4 articles | Viewed by 9659 | Submission Open

Keywords: cardiorenal medicine; diabetes; chronic renal failure; heart failure; cardiorenal syndrome; nephrocardiology

(This special issue belongs to the Section Cardiovascular Medicine)

Pain Management: Current Challenges and Future Prospects

edited by Gian Marco Petroni

submission deadline 25 Aug 2026 | 5 articles | Viewed by 8733 | Submission Open

Keywords: chronic joint pain; radio frequency ablation; adipose-derived mesenchimal stem cells (ADMScs); intrarticular injection; facet joint injection with ADMScs

(This special issue belongs to the Section Anesthesiology)

Up-to-Date Research in Liver Transplantation

edited by

Pierluigi Toniutto

submission deadline 25 Aug 2026 | 5 articles | Viewed by 6925 | Submission Open

Keywords: liver transplantation; acute or chronic liver diseases; hepatitis C virus infection; hepatocellular carcinoma (HCC); cirrhosis; intrahepatic (ICCA), perihilar (PCCA) cholangiocarcinoma; unresectable liver metastases; acute or chronic liver failure (ACLF); acute alcoholic hepatitis (AAH)

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Recent Advances in Prevention, Management, and Rehabilitation of Head and Neck Injuries

edited by

Giovanni Barassi

, Pier Enrico Gallenga and

Roberta Di Pietro

submission deadline 25 Aug 2026 | 3 articles | Viewed by 6044 | Submission Open

Keywords: neck injuries; whiplash injuries; head injuries; concussion; neck pain; cervicalgia; post-concussive syndrome; post-concussive symptoms; vision disorders; hearing disorders; emergency care; emergency therapies; physical medicine and rehabilitation; musculoskeletal rehabilitation; sports medicine

(This special issue belongs to the Section Sports Medicine)

Shoulder and Elbow Surgery: Clinical Updates and Perspectives

edited by Taku Hatta, Akihiko Hasegawa and Takuma Yuri

submission deadline 25 Aug 2026 | 5 articles | Viewed by 5663 | Submission Open

Keywords: rotator cuff injuries; shoulder arthroplasty; elbow surgery; shoulder surgery; shoulder and elbow disease; arthroscopic surgery; orthopedic surgery

(This special issue belongs to the Section Orthopedics)

Clinical Diagnosis and Surgical Strategies Update on Ear Disorders: 2nd Edition

edited by

Eleonora M.C. Trecca

and

Andrea Albera

submission deadline 25 Aug 2026 | 5 articles | Viewed by 4905 | Submission Open

Keywords: middle ear; inner ear; endoscopic ear surgery; cholesteatoma; Menière’s disease; hearing loss; robotic surgery; oto-sclerosis

(This special issue belongs to the Section Otolaryngology)

Helicobacter pylori-Associated Intestinal Diseases and Beyond

edited by

Antonio Facciorusso

submission deadline 25 Aug 2026 | 4 articles | Viewed by 4265 | Submission Open

Keywords: IBD; Hp; stomach; celiac disease; diverticulosis; diverticulitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Etiology, Diagnosis, and Management of Upper Gastrointestinal Disorders: 2nd Edition

edited by

Hidekazu Suzuki

submission deadline 25 Aug 2026 | 2 articles | Viewed by 4076 | Submission Open

Keywords: esophagus; stomach; duodenum; DGBI; FGIDs; helicobacter; eosinophilic esophagitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current and Emerging Treatment Options in Chronic Liver Diseases

edited by Chandana B. Herath and Michael Praktiknjo

submission deadline 25 Aug 2026 | 2 articles | Viewed by 2884 | Submission Open

Keywords: liver disease; liver fibrosis; liver cirrhosis; portal hypertension; liver cancer; therapies; immunological therapies for liver cancer; diabetic liver; type 2 diabetes and obesity; spontaneous bacterial peritonitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Inflammatory Bowel Disease: Clinical Pathogenesis and Management Strategies

edited by

Francesco Colombo

submission deadline 25 Aug 2026 | 3 articles | Viewed by 2867 | Submission Open

Keywords: epithelial barrier dysfunction; intestinal microbiota dysbiosis; minimally invasive surgery in IBDs; disease monitoring; perianal disease treatment; surgical complications in IBD; prehabilitation; stoma formation and management; timing of surgery in IBDs; risk stratification for IBD surgery; patient-reported outcomes post-surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Recent Advances in Clinical Pharmacology Based on Pharmacokinetics

edited by

Magdalena Cuciureanu

Cristina Ghiciuc

and

Nina Filip

submission deadline 25 Aug 2026 | 1 articles | Viewed by 2540 | Submission Open

Keywords: PK/PD modeling; dose optimization; clinical decision-making tools; therapeutic drug monitoring; personalized medicine

(This special issue belongs to the Section Pharmacology)

Clinical Updates of Diagnosis and Treatment in Chronic Kidney Disease (CKD)

edited by

Juan F. Navarro-González

, Carmen Mora-Fernández and

Javier Donate-Correa

submission deadline 25 Aug 2026 | 1 articles | Viewed by 2431 | Submission Open

Keywords: CKD; CKD progression; biomarkers; disease-modifying treatments; diabetic kidney disease; cardiorenal disease; glomerunephritis; genetic kidney diseases

(This special issue belongs to the Section Nephrology & Urology)

Current and Emerging Strategies in Ischemic Stroke: Diagnosis, Treatment, and Prevention

edited by

Dougho Park

Hyoung Seop Kim

and

Jong Hun Kim

submission deadline 25 Aug 2026 | 2 articles | Viewed by 1797 | Submission Open

Keywords: diagnosis; digital medicine; epidemiology; ischemic stroke; machine learning; neurorehabilitation; prevention; stroke imaging; treatment

(This special issue belongs to the Section Clinical Neurology)

Gastrointestinal Cancer: Outcomes and Therapeutic Management—2nd Edition

edited by Maximos Frountzas

submission deadline 25 Aug 2026 | 2 articles | Viewed by 1515 | Submission Open

Keywords: surgical oncology; gastrointestinal cancer; esophageal; gastric; hepatic; biliary; pancreatic; colon; rectal; neoplasm

(This special issue belongs to the Section Oncology)

Complications of Laparoscopic Cholecystectomy: Surgical Outcomes and Clinical Challenges

edited by

Roberto Cirocchi

submission deadline 25 Aug 2026 | 1 articles | Viewed by 1268 | Submission Open

Keywords: laparoscopic cholecystectomy; bile duct injury; management of intraoperative injuries; surgical outcomes; postoperative infections

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Otologic Disorders and Hearing Impairment: From Diagnosis to Rehabilitation

edited by Andrea Albera and Andrea Canale

submission deadline 25 Aug 2026 | 1 articles | Viewed by 1104 | Submission Open

Keywords: otology; hearing loss; cochlear implants; middle ear surgery; otitis media; otosclerosis; auditory rehabilitation; ves-tibular disorders; hearing aid; bone-conduction implants

(This special issue belongs to the Section Otolaryngology)

Motor Activity and Cognitive Development in Early Childhood: Clinical Implications

edited by

Michele Roccella

and

Daniela Smirni

submission deadline 25 Aug 2026 | Viewed by 499 | Submission Open

Keywords: motor activity; cognitive development; early childhood; neurodevelopmental disorders; autism spectrum disorder; attention-deficit/hyperactivity disorder; developmental coordination disorder; preterm birth

(This special issue belongs to the Section Clinical Neurology)

Hand Surgery in Practice: Current Evidence and Emerging Techniques

edited by Guy Rubin

submission deadline 25 Aug 2026 | Viewed by 379 | Submission Open

Keywords: trauma; mallet; burn; nerve; tendon

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Spinal Surgery: Recent Advances and Future Perspectives

edited by

Yoshiharu Kawaguchi

submission deadline 25 Aug 2026 | Viewed by 373 | Submission Open

Keywords: spine surgery; diagnostic technology; AI; images; biomarkers; genetics; robotic surgery; minimum invasive surgery; pain control; VR

(This special issue belongs to the Section Orthopedics)

Novel Approaches to the Treatment and Rehabilitation of Traumatic Brain Injury

edited by

Mario Ganau

submission deadline 25 Aug 2026 | Viewed by 314 | Submission Open

Keywords: traumatic brain injury; rehabilitation; neurotrauma

(This special issue belongs to the Section Brain Injury)

Contemporary Insights in Pulmonary Hypertension: Moving from Algorithms to Phenotypes

edited by Rahul Gupta Argula

submission deadline 25 Aug 2026 | Viewed by 256 | Submission Open

Keywords: pulmonary hypertension; pulmonary arterial hypertension; pulmonary vascular disease; chronic thromboembolic pulmonary hypertension; hypoxic conditions; respiratory therapy

(This special issue belongs to the Section Respiratory Medicine)

Recent Advances and Future Perspective of Subarachnoid Hemorrhage

edited by

Tihamer Molnar

submission deadline 26 Aug 2026 | Viewed by 379 | Submission Open

Keywords: subarachnoid bleeding; neuromonitoring; neuroimaging; delayed cerebral infarction; biomarkers; personalized medicine; AI-guided decision support; outcome

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Musculoskeletal Physiotherapy

edited by

George Georgoudis

submission deadline 26 Aug 2026 | Viewed by 275 | Submission Open

Keywords: telerehabilitation in musculoskeletal medicine; wearable sensors; therapeutic exercise; alternative exercise tech-niques; pain management; musculoskeletal assessment tools

(This special issue belongs to the Section Clinical Rehabilitation)

Orthodontics: State of the Art and Perspectives

edited by

Camelia Szuhanek

and

Irina Nicoleta Zetu

submission deadline 28 Aug 2026 | 17 articles | Viewed by 34113 | Submission Open

Keywords: orthodontics; digital orthodontics; intraoral scanners; facial scanners; treatment planning; interdisciplinary treatment; orthodontic implants

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Neuromuscular Diseases and Musculoskeletal Disorders

edited by

Anna Christakou

submission deadline 28 Aug 2026 | 5 articles | Viewed by 7503 | Submission Open

Keywords: neuromuscular diseases; osteoporosis; fractures; muscle weakness; muscle intolerance; shoulder dysfunction; myopathy; physiotherapy; rehabilitation

(This special issue belongs to the Section Clinical Neurology)

Movement Analysis in Rehabilitation

edited by Paola Contessa

submission deadline 28 Aug 2026 | 4 articles | Viewed by 6228 | Submission Open

Keywords: clinical biomechanics; engineering methods; human movement; motor control; muscle force; musculoskeletal disorders; neuromuscular diseases; posture and balance; rehabilitation

(This special issue belongs to the Section Orthopedics)

Clinical Updates in Heart Failure: Innovations in Diagnosis, Therapy and Management

edited by Paolo Severino

submission deadline 28 Aug 2026 | 8 articles | Viewed by 5339 | Submission Open

Keywords: heart failure; HFrEF therapy; HFpEF phenotyping; right ventricular dysfunction; renal congestion assessment; diuretic resistance; NT-proBNP dynamics; cardiac imaging; post-discharge management

(This special issue belongs to the Section Cardiology)

Clinical Updates in Stem Cell Transplants

edited by Daniele Avenoso and Michele Malagola

submission deadline 28 Aug 2026 | 3 articles | Viewed by 4121 | Submission Open

Keywords: AML; CML; lymphoma; allo-HSCT; GVHD; MDS; AA

(This special issue belongs to the Section Hematology)

Tumor Microenvironment—Current Status and Therapeutic Targets

edited by

Rashi Kalra

submission deadline 28 Aug 2026 | 2 articles | Viewed by 3855 | Submission Open

Keywords: tumor microenvironment (TME); cancer immunology; immune checkpoint inhibitors; cancer biology; targeted therapies

(This special issue belongs to the Section Oncology)

Towards a New Paradigm: Opioid-Free and Opioid-Sparing Strategies in Modern Anesthesia

edited by

Kassiani Theodoraki

submission deadline 28 Aug 2026 | 2 articles | Viewed by 3694 | Submission Open

Keywords: opioid-free anesthesia; opioid-sparing strategies; multimodal analgesia; regional anesthesia; non-opioid analgesics; enhanced recovery after surgery (ERAS); perioperative pain management; postoperative analgesia; anesthesia innovation; chronic pain prevention; patient-centered anesthesia; clinical outcomes in anesthesia

(This special issue belongs to the Section Anesthesiology)

Emerging Therapies: Clinical Trials and Insights in Psoriasis

edited by

Beata Kowalewska

and Elżbieta Krajewska-Kułak

submission deadline 28 Aug 2026 | 3 articles | Viewed by 2685 | Submission Open

Keywords: psoriasis; clinical trials; biomarkers; psychodermatology; treatment; modern therapy; individualized therapy

(This special issue belongs to the Section Dermatology)

Epidemiology Associated Risks and Intervention Strategies of Childhood Obesity

edited by

María M. Morales Suárez-Varela

Antonio Castillo-Paredes

and Eduardo Guzmán-Muñoz

submission deadline 28 Aug 2026 | Viewed by 646 | Submission Open

Keywords: childhood obesity; overweight; eating disorders; nutritional programs; psychological interventions; physical activity exercise; sport; physical well-being; mental well-being; quality of life

(This special issue belongs to the Section Clinical Pediatrics)

Drug-Related Problems: Clinical Pharmacy and Safety of Pharmacotherapy

edited by

Mariola Drozd

and

Jakub Pawlikowski

submission deadline 30 Aug 2026 | 3 articles | Viewed by 5893 | Submission Open

Keywords: adverse drug reaction; drug-related problems; drug formulation technology; safety of pharmacotherapy; clinical pharmacy; pharmaceutical care; pharmacology

(This special issue belongs to the Section Pharmacology)

Clinical Updates in Trauma and Emergency Medicine

edited by Yong-Soo Cho and Hyun Ho Ryu

submission deadline 31 Aug 2026 | 6 articles | Viewed by 9020 | Submission Open

Keywords: emergency medicine; epidemiology; cardiovascular disease

(This special issue belongs to the Section Emergency Medicine)

Infectious Diseases and Host Responses: Clinical, Immunological, and Outcome-Orientated Perspectives

edited by

Nicoleta Negruț

submission deadline 31 Aug 2026 | 3 articles | Viewed by 3468 | Submission Open

Keywords: microbiology; infection; resistance; epidemiology; microbiome; prevention; therapy

(This special issue belongs to the Section Infectious Diseases)

Chronic Obstructive Pulmonary Disease (COPD): Treatment and Management—Second Edition

edited by

Maurizio Marvisi

and Alfredo Antonio Chetta

submission deadline 31 Aug 2026 | 3 articles | Viewed by 2461 | Submission Open

Keywords: chronic obstructive pulmonary disease (COPD); treatable traits; precision medicine; COPD comorbidities; COPD mortality

(This special issue belongs to the Section Respiratory Medicine)

The New Perspective in Transcatheter Aortic Valve Implantation (TAVI)

edited by Salvatore Giordano, Arturo Giordano and Nicola Corcione

submission deadline 31 Aug 2026 | 3 articles | Viewed by 1912 | Submission Open

Keywords: transcatheter aortic valve implantation (TAVI); structural heart intervention; aortic stenosis; valve technology and durability; imaging and procedural optimization

(This special issue belongs to the Section Cardiovascular Medicine)

Interventional Cardiology: Emerging Insights into Therapeutic Advancements

edited by Dong-Hyeok Kim

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1786 | Submission Open

Keywords: conduction system pacing (CSP); left bundle branch area pacing (LBBAP); interventional electrophysiology; advanced pacing strategies; heart failure device therapy

(This special issue belongs to the Section Cardiology)

Recent Advances and Future Perspectives on Spinal Surgeries

edited by

Sung-kyu Kim

submission deadline 31 Aug 2026 | 1 articles | Viewed by 941 | Submission Open

Keywords: minimally invasive spine procedures; robotic-assisted spine surgery; image-guided navigation; spinal implants and biomaterials; artificial intelligence in spinal care; regenerative spine therapies; clinical outcomes in spine surgery; future trends in spinal interventions

(This special issue belongs to the Section Orthopedics)

Management of Complex Orthopaedic Trauma and Bone Infection

edited by

Georg Mattiassich

submission deadline 31 Aug 2026 | 1 articles | Viewed by 510 | Submission Open

Keywords: complex orthopaedic trauma; fracture-related infection (FRI); bone and implant-associated infection; chronic osteomyelitis; post-traumatic infection; biofilm-associated infection; advanced fracture management; limb reconstruction; nonunion and delayed union; multidisciplinary trauma care

(This special issue belongs to the Section Orthopedics)

Clinical Management of Type 1 Diabetes: 2nd Edition

edited by Carmen Quirós

submission deadline 31 Aug 2026 | Viewed by 309 | Submission Open

Keywords: type 1 diabetes; continuous glucose monitoring; hybrid closed loop; hypoglycemia; physical activity; new onset type 1 diabetes; pre-stage 3 type 1 diabetes; smart insulin pens

(This special issue belongs to the Section Endocrinology & Metabolism)

Molecular Mechanisms and Therapeutic Strategies in Pediatric Immune Dysregulation

edited by Rita Consolini and

Giorgio Costagliola

submission deadline 31 Aug 2026 | Viewed by 189 | Submission Open

Keywords: immune dysregulation; autoimmunity; inborn errors of immunity; targeted therapies; immunomodulatory treatments; genetics; gene therapy; hematopoietic stem cell transplantation

(This special issue belongs to the Section Immunology & Rheumatology)

Advances in Maxillofacial Surgery—Historical and Future Perspectives and Controversies

edited by

Kamil Nelke

Maciej Dobrzyński

and

Michał Gontarz

submission deadline 1 Sep 2026 | 8 articles | Viewed by 11728 | Submission Open

Keywords: oral oncology; facial skeleton; oral cavity; surgical approaches; head and neck; parotid tumors; jaw cysts and tumors; bone healing; patient-specific solutions; surgery planning; artificial intelligence; soft tissues; cancers and tumors of the oral cavity; microsurgery perspectives; open surgery; endoscopic surgery; trauma surgery; facial traumatology; bone and soft tissues healing after trauma; jaw deformities; orthognathic surgery today and tomorrow

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

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