Current and Emerging Treatment Options in Chronic Liver Diseases
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 23
Special Issue Editor
2. Department of Surgery, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Heidelberg, VIC 3084, Australia
Interests: liver diseases; liver fibrosis; liver cirrhosis; portal hypertension; liver cancer; diabetic liver diseases
Special Issue Information
Dear Colleagues,
Liver fibrosis is initiated as a part of the wound healing response to tissue injury. The most common injurious agents for chronic liver disease (CLD) include chronic viral infections (e.g., hepatitis B and C), excessive alcohol consumption, metabolic dysfunction-associated steatotic liver disease (MASLD), and cholestatic diseases such as primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC). The end result of chronic injury to the liver is cirrhosis, in which there is extensive scar formation, distortion of the liver parenchyma by septae and nodule formation, and alterations in blood flow. Cirrhosis can be associated with the development of liver cancer, leading to liver failure and death. Thus, cirrhosis, and its major life-threatening complications of portal hypertension (PHT) and variceal bleeding, as well as liver cancer are responsible for a large number of deaths worldwide annually. However, the treatment options for CLD and liver cancer are limited. Therefore, there is a major unmet need for the development of more effective and better-tolerated treatments for CLD, including liver cancer. To address these areas, the Journal of Clinical Medicine has set up this Special Issue for potential authors to highlight recent advances in the diagnosis and treatment of CLD, including liver cancer, through clinical research. We therefore invite authors to contribute with highly innovative original papers or critical reviews in this field.
Dr. Chandana B. Herath
Guest Editor
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Keywords
- liver disease
- liver fibrosis
- liver cirrhosis
- portal hypertension
- liver cancer
- therapies
- immunological therapies for liver cancer
- diabetic liver
- type 2 diabetes and obesity
- spontaneous bacterial peritonitis
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