Inflammatory Bowel Disease: Clinical Pathogenesis and Management Strategies
This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".
Special Issue Information
Dear Colleagues,
Inflammatory bowel diseases (IBDs), comprising Crohn’s disease and ulcerative colitis, are chronic, relapsing conditions of the gastrointestinal tract with rising global incidence. The primary aim of current research and clinical care is to elucidate the complex pathogenesis of IBDs and to optimize individualized, long-term management strategies. IBD pathogenesis involves a multifactorial interplay of genetic susceptibility, environmental factors, epithelial barrier dysfunction, and dysregulated mucosal immune responses.
Despite therapeutic advances, key challenges remain: identifying predictive biomarkers, preventing disease progression, and calibrating surgical interventions.
This Special Issue of the Journal of Clinical Medicine, entitled “Inflammatory Bowel Disease: Clinical Pathogenesis and Management Strategies”, is devoted to articles that focus on the optimization of IBD care, particularly considering treat-to-target strategies, individualized surgical risk stratification, and tailored surgical as well as medical techniques. Importantly, articles that address unmet challenges and opportunities to improve outcomes are welcome.
Dr. Francesco Colombo
Guest Editor
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Keywords
- epithelial barrier dysfunction
- intestinal microbiota dysbiosis
- minimally invasive surgery in IBDs
- disease monitoring
- perianal disease treatment
- surgical complications in IBD
- prehabilitation
- stoma formation and management
- timing of surgery in IBDs
- risk stratification for IBD surgery
- patient-reported outcomes post-surgery
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Published Papers
J. Clin. Med. - ISSN 2077-0383