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Inflammatory Bowel Disease: Clinical Pathogenesis and Management Strategies

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: 28 February 2026

Special Issue Editor


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Guest Editor
Department of General Surgery, Department of Biomedical and Clinical Sciences “L. Sacco”, University of Milan, ASST Fatebenefratelli Sacco, 20157 Milan, Italy
Interests: inflammatory bowel diseases (IBDs); colorectal tumors; diverticular disease; intestinal obstruction conditions; functional gastrointestinal disorders; intestinal motility disorders; intestinal hemorrhage; minimally invasive colorectal surgery techniques

Special Issue Information

Dear Colleagues,

Inflammatory bowel diseases (IBDs), comprising Crohn’s disease and ulcerative colitis, are chronic, relapsing conditions of the gastrointestinal tract with rising global incidence. The primary aim of current research and clinical care is to elucidate the complex pathogenesis of IBDs and to optimize individualized, long-term management strategies. IBD pathogenesis involves a multifactorial interplay of genetic susceptibility, environmental factors, epithelial barrier dysfunction, and dysregulated mucosal immune responses.

Despite therapeutic advances, key challenges remain: identifying predictive biomarkers, preventing disease progression, and calibrating surgical interventions.

This Special Issue of the Journal of Clinical Medicine, entitled “Inflammatory Bowel Disease: Clinical Pathogenesis and Management Strategies”, is devoted to articles that focus on the optimization of IBD care, particularly considering treat-to-target strategies, individualized surgical risk stratification, and tailored surgical as well as medical techniques. Importantly, articles that address unmet challenges and opportunities to improve outcomes are welcome.

Dr. Francesco Colombo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • epithelial barrier dysfunction
  • intestinal microbiota dysbiosis
  • minimally invasive surgery in IBDs
  • disease monitoring
  • perianal disease treatment
  • surgical complications in IBD
  • prehabilitation
  • stoma formation and management
  • timing of surgery in IBDs
  • risk stratification for IBD surgery
  • patient-reported outcomes post-surgery

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Published Papers

This special issue is now open for submission.
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