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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Imaging and Therapeutic Strategies for Cardiomyopathy Care
edited by Fabio Vagnarelli and
submission deadline 20 Sep 2026 | Viewed by 275 | Submission Open
Keywords: cardiomyopathy; amyloidosis; cardiovascular magnetic resonance; cardiogenetics; multimodality imaging; therapeutic strategies
(This special issue belongs to the Section Cardiology)
Diagnosis and Treatment in Chronic Obstructive Pulmonary Disease
edited by Michael Kassirer
submission deadline 20 Sep 2026 | Viewed by 275 | Submission Open
Keywords: COPD phenotyping; biomarkers; precision medicine; symptom-centered care; comorbidities
(This special issue belongs to the Section Respiratory Medicine)
Advanced Technologies in Orthopedic Surgery: Progress, Challenges and Opportunities
edited by and Daniel Pérez-Prieto
submission deadline 20 Sep 2026 | Viewed by 272 | Submission Open
Keywords: orthopedic surgery; traumatology; orthopedic infections; osteomyelitis; prosthetic joint infections; robotic-assisted surgery; biomaterials; 3D printing surgical planning; AI in orthopedics
(This special issue belongs to the Section Orthopedics)
The Next Era of Breast Reconstruction: Advances and Ongoing Challenges
edited by
submission deadline 20 Sep 2026 | Viewed by 268 | Submission Open
Keywords: breast reconstruction; silicone implant; autologous tissue; acellular dermal matrix; seroma; outcome; complication
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Stroke Recovery and Neuroplasticity: Bridging Research to Rehabilitation submission deadline 20 Sep 2026 | Viewed by 263 | Submission Open
Keywords: stroke; neuroplasticity; artificial intelligence; EEG; neuromodulation; TMS; tDCS; tACS; functional recovery prediction
(This special issue belongs to the Section Clinical Neurology)
Comprehensive Management of Colonic Diverticulitis: Current Perspectives and Treatment Guidelines
edited by
submission deadline 20 Sep 2026 | Viewed by 259 | Submission Open
Keywords: acute diverticulitis; diverticular disease; complicated diverticulitis; Hinchey classification; colonic diverticulitis; non-operative management; antibiotic stewardship; laparoscopic colectomy; Hartmann’s procedure
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Supportive Care Across Proton and Photon Radiotherapy: Access, Challenges, and Solutions
edited by Safora Johansen
submission deadline 20 Sep 2026 | Viewed by 256 | Submission Open
Keywords: photon therapy; PBT; supportive care; cancer patients; caregivers; access to care
(This special issue belongs to the Section Oncology)
Management and Treatment Strategies for Diabetic Kidney Disease
edited by Luca Visconti
submission deadline 20 Sep 2026 | Viewed by 255 | Submission Open
Keywords: diabetic kidney disease; hemodialysis; cardiovascular; dialysis; diabetic nephropathy; diabetes
(This special issue belongs to the Section Nephrology & Urology)
Clinical Management of Thyroid Diseases
edited by Diana Loreta Pãun, Mihaela Stanciu and Mihaela Popescu
submission deadline 20 Sep 2026 | Viewed by 253 | Submission Open
Keywords: thyroid genetics; autoimmune thyroiditis; thyroid cancer; thyroid puncture techniques; radiofrequency ablation treatment
(This special issue belongs to the Section Endocrinology & Metabolism)
Emerging Therapeutic Interventions for Eating Disorders Through Psychology
edited by Anita Federici and
submission deadline 20 Sep 2026 | Viewed by 251 | Submission Open
Keywords: eating disorders; psychological interventions; emerging psychotherapies; dialectical behavior therapy (DBT); transdiagnostic approaches; emotion regulation; severe and enduring eating disorders; treatment development and adaptation; implementation and feasibility; integrated medical–psychological care
(This special issue belongs to the Section Mental Health)
Current Concepts in Prostate Cancer: From Early Detection to Therapeutic Innovations
edited by , and Igor Duquesne
submission deadline 20 Sep 2026 | Viewed by 242 | Submission Open
Keywords: prostate cancer; miRNA; PSMA PET/CT; radiomics; multiparametric MRI (mpMRI); active surveillance; robot-assisted radical prostatectomy (RARP); focal therapy; functional outcomes; Quality of Life (QoL)
(This special issue belongs to the Section Oncology)
Advances in Burn Management—2nd Edition
edited by Juan P. Barret
submission deadline 20 Sep 2026 | Viewed by 236 | Submission Open
Keywords: burns; wound healing; immune response; stem cells; burn surgery; rehabilitation; PROMs; PREMs
(This special issue belongs to the Section General Surgery)
Novel Diagnostic and Therapeutic Methods in Jaundice and Related Diseases
edited by and Angela C Cheung
submission deadline 20 Sep 2026 | Viewed by 233 | Submission Open
Keywords: primary biliary cholangitis; Alagille syndrome; cholestasis; familial intrahepatic cholestasis; ileal bile acid transporters inhibitors; pruritus
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Pancreato-Biliary Interventional Endoscopy: 3rd Edition
edited by
submission deadline 20 Sep 2026 | Viewed by 227 | Submission Open
Keywords: endotherapy; pancreatobiliary disease; pancreatobiliary endoscopy; interventional EUS; ERCP; biliary access; biliary cannulation; endoscopic stenting; biliary drainage; pancreatic drainage; EUS-guided biliary drainage (EUS-BD); EUS-guided pancreatic drainage (EUS-PD); cholangioscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Prevention and Treatment of Cancer-Associated Venous Thromboembolism
edited by
submission deadline 20 Sep 2026 | Viewed by 151 | Submission Open
Keywords: oncology; cancer-associated thrombosis; cancer-associated thromboembolism; venous thromboembolism; prevention; treatment; anticoagulation
(This special issue belongs to the Section Hematology)
Advances in the Clinical Management of Pregnancy-Related Complications submission deadline 22 Sep 2026 | 2 articles | Viewed by 1268 | Submission Open
Keywords: pregnancy; complications; hypertension; diabetes; placenta accreta; preterm labor; infections
(This special issue belongs to the Section Obstetrics & Gynecology)
New Insights into Pancreatic Surgery: 2nd Edition
edited by Mario Serradilla-Martín and José Manuel Ramia
submission deadline 22 Sep 2026 | Viewed by 281 | Submission Open
Keywords: pancreas; pancreatectomy; surgery; outcomes; cancer; fistula; minimally invasive surgery; IPMT
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
The Importance of Advances in Urological Surgery: From Open Surgery to Minimally Invasive Surgery submission deadline 23 Sep 2026 | 3 articles | Viewed by 2084 | Submission Open
Keywords: artificial intelligence; minimally invasive surgery; reconstructive surgical procedures; robotic surgical procedures; surgical oncology; telesurgery; virtual reality; results in urological surgery; laser in urology
(This special issue belongs to the Section Nephrology & Urology)
Improving Diagnosis and Treatment of Vestibular Disorder: Latest Advances and Challenges
edited by , and Athanasia Korda
submission deadline 24 Sep 2026 | 4 articles | Viewed by 10638 | Submission Open
Keywords: vestibular system; balance disorders; dizziness; vertigo; vestibular testing; videonystagmography; video head impulse test; vestibular evoked myogenic potentials; vestibular rehabilitation therapy
(This special issue belongs to the Section Otolaryngology)
Musculoskeletal Disorders: Clinical Diagnosis, Treatment and Rehabilitation submission deadline 25 Sep 2026 | 10 articles | Viewed by 53327 | Submission Open
Keywords: musculoskeletal disorders; therapeutic exercise; functional evaluation; rehabilitation protocols; musculoskeletal ultrasound; biomechanical análisis; quality of life; functional assessment of the musculoskeletal system; strength training; physical therapy; morphofunctional assessment; conservative treatments; range of motion evaluation; randomized controlled trials
(This special issue belongs to the Section Clinical Rehabilitation)
Gynecologic and Obstetric Pathologies: From Birth to Menopause (Third Edition) submission deadline 25 Sep 2026 | 12 articles | Viewed by 49764 | Submission Open
Keywords: obstetrics; gynecology; pathology; pediatric and adolescent gynecology; menopause; urinary disorders; infertility; gynecologic oncology; maternal–fetal medicine; incontinence; menstruation; reproduction; polycystic ovarian syndrome; endometriosis; dysmenorrhea; assisted reproduction; IVF; laparoscopy; hysteroscopy; gynecologic robotic surgery; high-risk pregnancy
(This special issue belongs to the Section Obstetrics & Gynecology)
Airway Management: From Basic Techniques to Innovative Technologies
edited by Kunal Karamchandani and Sheila Nainan Myatra
submission deadline 25 Sep 2026 | 10 articles | Viewed by 25881 | Submission Open
Keywords: airway management; physiologically difficult airway; videolaryngoscopy; esophageal intubation; artificial intelligence
(This special issue belongs to the Section Intensive Care)
Acute Care for Traumatic Injuries and Surgical Outcomes: 2nd Edition
edited by Matthias Fröhlich and Michael Caspers
submission deadline 25 Sep 2026 | 8 articles | Viewed by 14743 | Submission Open
Keywords: trauma injuries; orthopedics; polytrauma; emergency care; coagulation disorders; fractures; surgical outcomes; acute care; diagnostic imaging
(This special issue belongs to the Section Emergency Medicine)
Advances in Perioperative Care: Challenges and Perspectives in Enhanced Recovery After Surgery, Perioperative Optimization and Prehabilitation: 2nd Edition
edited by and María Rodríguez Pérez
submission deadline 25 Sep 2026 | 7 articles | Viewed by 10367 | Submission Open
Keywords: perioperative care; enhanced recovery after surgery; prehabilitation; minimally invasive surgery; patient-related outcome measures; colorectal surgery; general surgery; thoracic surgery; vascular surgery; optimal functional recovery
(This special issue belongs to the Section General Surgery)
Contemporary Trends in Cardiovascular Prevention
edited by Alessandro Durante and
submission deadline 25 Sep 2026 | 3 articles | Viewed by 8882 | Submission Open
Keywords: interventional cardiology; coronary artery disease; carotid artery disease; aortic valve disease; left atrial appendage closure; hypercholesterolemia
(This special issue belongs to the Section Cardiovascular Medicine)
Breast Cancer: Advances in Clinical and Personalized Practices
edited by Massimo Lodi and Sébastien Molière
submission deadline 25 Sep 2026 | 6 articles | Viewed by 8356 | Submission Open
Keywords: breast cancer; radiology; surgical oncology; breast reconstruction; personalized medicine; quality of life; multidisci-plinary approach; new technologies
(This special issue belongs to the Section Oncology)
Acute Trauma and Trauma Care in Orthopedics: 2nd Edition submission deadline 25 Sep 2026 | 11 articles | Viewed by 7565 | Submission Open
Keywords: orthopedics; trauma; injury; musculoskeletal; surgery; knee; osteoarthritis; spinal deformity; fracture; joint replacement; hip fractur; fragility fracture; minimally invasive surgery; post-traumatic care and rehabilitation; pain management; emergency assessment
(This special issue belongs to the Section Orthopedics)
Multidisciplinary Approach to the Diagnosis and Treatment of Temporomandibular Disorders: Patient Care Challenges—2nd Edition submission deadline 25 Sep 2026 | 4 articles | Viewed by 7500 | Submission Open
Keywords: multidisciplinary approach; mental health; bruxism; masticatory muscles; temporomandibular joint; orofacial pain; temporomandibular disorders
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Hepatobiliary and Pancreatic (HPB) Surgery: Current Status and Future Perspectives
edited by Andrea Benedetti Cacciaguerra and Paolo Vincenzi
submission deadline 25 Sep 2026 | 4 articles | Viewed by 7047 | Submission Open
Keywords: hepatobiliary and pancreatic surgery; laparoscopic surgery; robot-assisted surgery; artificial intelligence; augmented reality; indocyanine green; liver tumors; pancreatic tumors
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Insights and Advances in Structural Heart Disease
edited by
submission deadline 25 Sep 2026 | 6 articles | Viewed by 6947 | Submission Open
Keywords: TAVR; Mitra-Clip; Tri-Clip; Pascal; TricValve; PFO closure; LAAO closure; cardiac CT; cardiac MRI; transoesopha-geal echocardiography
(This special issue belongs to the Section Cardiology)
Recent Advances in Prenatal Diagnosis and Maternal Fetal Medicine submission deadline 25 Sep 2026 | 2 articles | Viewed by 6687 | Submission Open
Keywords: prenatal; obstetrics; fetal abnormalities; intrauterine treatments; genetic disorders; pregnancy
(This special issue belongs to the Section Obstetrics & Gynecology)
Multiple Sclerosis and Demyelinating Diseases: Diagnosis, Treatment and Prognosis
edited by Alberto Gajofatto
submission deadline 25 Sep 2026 | 3 articles | Viewed by 6656 | Submission Open
Keywords: multiple sclerosis; neuromyelitis optica; MOG-antibody disease; diagnosis; prognosis; treatment
(This special issue belongs to the Section Clinical Neurology)
Pregnancy and Delivery Complications: Bridging Research and Clinical Practice
edited by , Andrei Mihai Malutan and Răzvan Ciortea
submission deadline 25 Sep 2026 | 4 articles | Viewed by 5555 | Submission Open
Keywords: maternal–fetal medicine; obstetric complications; perinatal health; pelvic floor disorders; childbirth perineal trauma; risk stratification; patient-reported outcomes; patient-reported outcome measures
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Schizophrenia and Related Psychotic Disorders
edited by Giovanni Camardese and Michele Ribolsi
submission deadline 25 Sep 2026 | 4 articles | Viewed by 5219 | Submission Open
Keywords: psychosis; schizophrenia; severe mental illness; psychopharmacology; negative symptoms; antipsychotics
(This special issue belongs to the Section Mental Health)
Novel Developments in Dental and Oral Surgery submission deadline 25 Sep 2026 | 4 articles | Viewed by 5129 | Submission Open
Keywords: guided bone regeneration; dental implant osseointegration; laser dentistry; maxillofacial reconstruction; sinus lift techniques
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
New Insights into Acne Vulgaris Treatment and Management Strategies
edited by Jo Linda Maria Sinagra
submission deadline 25 Sep 2026 | 2 articles | Viewed by 4792 | Submission Open
Keywords: acne; hormonal treatments; isotretinoin; laser therapy; antibiotic
(This special issue belongs to the Section Dermatology)
Periodontitis and Systemic Health: Exploring the Oral-Systemic Connection
edited by and Phoebus Madianos
submission deadline 25 Sep 2026 | 3 articles | Viewed by 4447 | Submission Open
Keywords: periodontal disease; systemic diseases; cardiovascular disease; diabetes mellitus; adverse pregnancy outcomes; respiratory disease; neurodegenerative disorders; obesity; respiratory diseases; chronic kidney disease
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Advances in Treatment and Prognosis for Acute Type A and Type B Aortic Dissections
edited by
submission deadline 25 Sep 2026 | 4 articles | Viewed by 4393 | Submission Open
Keywords: acute aortic dissection; stent graft; false lumen expansion; thoracic endovascular aortic repair; initial surgery for Type A acute aortic dissection; frozen elephant trunk
(This special issue belongs to the Section Cardiovascular Medicine)
Meibomian Gland Dysfunction and Dry Eye Diseases
edited by and
submission deadline 25 Sep 2026 | 5 articles | Viewed by 3643 | Submission Open
Keywords: meibomian gland; meibomian gland dysfunction; dry eye disease; ocular surface; meibography; lipid layer; tear film; inflammation; therapy; diagnosis; epidemiology; clinical study
(This special issue belongs to the Section Ophthalmology)
Diagnosis and Treatment for Hearing Loss: Expert Views
edited by and John L. Dornhoffer
submission deadline 25 Sep 2026 | 2 articles | Viewed by 2686 | Submission Open
Keywords: hearing loss; cochlear implants; hearing aid technology; regenerative medicine; diagnostic audiology
(This special issue belongs to the Section Otolaryngology)
New Clinical Advances in Sudden Cardiac Arrest and Ventricular Arrhythmias: 2nd Edition
edited by
submission deadline 25 Sep 2026 | 1 articles | Viewed by 2624 | Submission Open
Keywords: cardiac arrest; defibrillation; ventricular tachycardia; ventricular fibrillation; catheter ablation; non-invasive ablation; neuromodulation; stellate ganglion block
(This special issue belongs to the Section Cardiology)
Current Advances and Future Perspectives of Sepsis and Septic Shock
edited by Filippo Mearelli and Gianni Biolo
submission deadline 25 Sep 2026 | 2 articles | Viewed by 2296 | Submission Open
Keywords: sepsis; epidemiology; biomarkers; diagnosis; predictive models; prognostication
(This special issue belongs to the Section Emergency Medicine)
Latest Advances in Ocular Surface Diseases
edited by Barbara Burgos-Blasco
submission deadline 25 Sep 2026 | 2 articles | Viewed by 2010 | Submission Open
Keywords: cornea; keratitis; ocular surface disease; dry eye; corneal ulcer; keratoplasty; conjunctival disease
(This special issue belongs to the Section Ophthalmology)
Latest Advances in Minimally Invasive Spine Surgery
edited by Fabian Sommer and
submission deadline 25 Sep 2026 | 2 articles | Viewed by 1849 | Submission Open
Keywords: minimally invasive spine surgery (MISS); advances in spine surgery; future directions of MISS; navigation and orientation; intramedullary/extramedullary tumor resections; emerging technologies in MISS (robotics, augmented reality, artificial intelligence, etc.); degenerative spine; patient safety in MISS
(This special issue belongs to the Section Clinical Neurology)
Clinical Updates and Perspectives in Atrial Fibrillation
edited by Riyaz Somani and
submission deadline 25 Sep 2026 | 1 articles | Viewed by 1538 | Submission Open
Keywords: atrial fibrillation; catheter ablation; risk prediction; stroke prevention; digital health and artificial intelligence
(This special issue belongs to the Section Cardiology)
Idiopathic Thrombocytopenic Purpura (ITP) and Thrombotic Thrombocytopenic Purpura (TTP): Pathophysiology, Clinical Practice and Future Developments
edited by María Eva Mingot Castellano
submission deadline 25 Sep 2026 | 2 articles | Viewed by 1507 | Submission Open
Keywords: ITP; TTP; thrombocytopenia; autoimmune; bleeding; thrombosis; caplacizumab; steroids; plasma exchange; infections; thrombopoetin; thrombopoetin analogs; immunosuppressive; immunomodulation; quality of life; fatigue
(This special issue belongs to the Section Hematology)
Corneal Surgery: From Innovation to Clinical Practice
edited by Joanna Wasielica-Poslednik
submission deadline 25 Sep 2026 | 1 articles | Viewed by 1488 | Submission Open
Keywords: keratoplasty; penetrating keratoplasty; DMEK; eye banking; corneal surgery
(This special issue belongs to the Section Ophthalmology)
Emergency Surgery: Recent Advances and Practical Strategies
edited by Avi Benov
submission deadline 25 Sep 2026 | 2 articles | Viewed by 1283 | Submission Open
Keywords: emergency surgery; acute care surgery; trauma; prehospital care; early decision-making; clinical outcomes; risk stratification; real-world evidence; registries
(This special issue belongs to the Section Emergency Medicine)
Tendon and Ligament Injury and Current Strategies for Tendon and Ligament Regeneration
edited by Andrej Čretnik, Bore Bakota and Dejan Blažević
submission deadline 25 Sep 2026 | 1 articles | Viewed by 1074 | Submission Open
Keywords: tendons; ligaments; injuries; tendinopathies; minimally invasive surgery; functional treatment; tissue engineering; novelties
(This special issue belongs to the Section Orthopedics)
Clinical Advances in General and Regional Anesthesia
edited by Luciano Frassanito
submission deadline 25 Sep 2026 | 1 articles | Viewed by 1065 | Submission Open
Keywords: oncoanesthesia; perinatal anesthesia; ventilatory support; hemodynamic monitoring; regional anesthesia
(This special issue belongs to the Section Anesthesiology)
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