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Idiopathic Thrombocytopenic Purpura (ITP) and Thrombotic Thrombocytopenic Purpura (TTP): Pathophysiology, Clinical Practice and Future Developments

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Hematology".

Deadline for manuscript submissions: 25 September 2026 | Viewed by 19

Special Issue Editor


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Guest Editor
Hematology Department, Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla (IBIS/CSIC), 41013 Sevilla, Spain
Interests: acquired hemophilia; ITP; TTP; MAT; haemolitic anemia; hemovigilance; transfusion; coagulopathies; massive bleeding; apheresis

Special Issue Information

Dear Colleagues,

The Journal of Clinical Medicine (JCM) invites submissions to our Special Issue entitled “Idiopathic Thrombocytopenic Purpura (ITP) and Thrombotic Thrombocytopenic Purpura (TTP): Pathophysiology, Clinical Practice and Future Developments”.

We welcome contributions spanning basic and translational mechanisms to cutting-edge diagnostics, with explicit attention to the transformative role of artificial intelligence (AI) and emerging technological tools (e.g., advanced imaging, multi-omics and decision-support systems) in refining phenotyping, risk stratification, and clinical workflows.

From a therapeutic standpoint, we seek state-of-the-art reviews and original research addressing current standards of care as well as the evolving therapeutic pipeline, including novel agents, biomarkers of response, and strategies for refractory disease and relapse prevention.

At the heart of this Special Issue lies a deliberate focus on underexplored domains—long-term comorbidities, survivorship, and the real-world impact on quality of life (QoL). We encourage authors to connect the dots between technical innovation and comprehensive care, moving beyond platelet counts toward outcomes that matter to patients.

By publishing in JCM, authors will help shape a high-visibility, field-defining reference for specialized hematologists worldwide.

Dr. María Eva Mingot Castellano
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ITP
  • TTP
  • thrombocytopenia
  • autoimmune
  • bleeding
  • thrombosis
  • caplacizumab
  • steroids
  • plasma exchange
  • infections
  • thrombopoetin
  • thrombopoetin analogs
  • immunosuppressive
  • immunomodulation
  • quality of life
  • fatigue

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Published Papers

This special issue is now open for submission.
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