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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Carotid Artery Disease: Current Hurdles and Future Perspectives
edited by Andrej Udelnow
submission deadline 20 Aug 2026 | 1 articles | Viewed by 610 | Submission Open
Keywords: carotid artery disease; carotid stenosis; endovascular technique; CEUS; elastography; high resolution CTA; atherosclerotic diseases; inflammatory diseases
(This special issue belongs to the Section Vascular Medicine)
New Insights into Gastrointestinal Surgery: Advances in Techniques and Treatment Approaches
edited by Gabriella Teresa Capolupo
submission deadline 20 Aug 2026 | Viewed by 497 | Submission Open
Keywords: gastroenterology; gastrointestinal surgery; colorectal surgery; robotic surgery; technologies; minimally invasive surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Updates on Reproductive Endocrinology in Children and Adolescents submission deadline 20 Aug 2026 | Viewed by 424 | Submission Open
Keywords: reproductive endocrinology; adolescents; male hypogonadism; female hypogonadism; reproductive metabolism; PCOS; POF; receptor abnormalities; menstrual cycle; transgender health; CAH; ovaries; gonads; hormones; sex development; amenorrhea; estrogen resistance; androgen resistance; teen pregnancy; oncology; preservation of fertility
(This special issue belongs to the Section Clinical Pediatrics)
Current Concepts and Technological Innovations in Hepato-Pancreato-Biliary Surgery and Transplantation
edited by Michele Finotti and Francesco D’Amico
submission deadline 20 Aug 2026 | Viewed by 372 | Submission Open
Keywords: hepato-pancreato-biliary surgery; hepato-pancreato-biliary transplantation; pancreatic cancer; hepatobiliary cancer; vascular reconstruction; minimally invasive in hepato-pancreato-biliary surgery; robotic techniques; organ-preservation strategies
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Orthopedic Infections: 2nd Edition
edited by
submission deadline 20 Aug 2026 | Viewed by 369 | Submission Open
Keywords: orthopedic surgery; orthopedic infections; periprosthetic joint infection; surgical site infection; infection management
(This special issue belongs to the Section Orthopedics)
Precision Neuroimaging in Mental and Behavioral Health Research
edited by Thomas Vanicek and Arkadiusz Komorowski
submission deadline 20 Aug 2026 | Viewed by 369 | Submission Open
Keywords: psychiatry; neuroimaging; addiction; substance use disorders (SUD); attention deficit hyperactivity disorder (ADHD); imaging genomics; imaging transcriptomics
(This special issue belongs to the Section Mental Health)
State of the Art in Bladder Cancer: Diagnostics and Treatment Strategies
edited by
submission deadline 20 Aug 2026 | Viewed by 360 | Submission Open
Keywords: bladder cancer; photodynamic diagnosis (PDD); bladder-sparing strategies; robotic-assisted surgery; single-port robotic cystectomy; older patients; immunotherapy; intravesical therapy; bladder preservation; minimally invasive urology; advanced bladder cancer; diagnostic innovation
(This special issue belongs to the Section Nephrology & Urology)
Optimizing Rehabilitation in Kidney Disease
edited by Henry H. L. Wu and Rajkumar Chinnadurai
submission deadline 20 Aug 2026 | Viewed by 339 | Submission Open
Keywords: chronic kidney disease; renal rehabilitation; exercise intervention; nutrition; multidisciplinary; frailty; physical conditioning
(This special issue belongs to the Section Clinical Rehabilitation)
Clinical Advances in Adult Deformities and Spinal Disorders: Surgical Treatment and Pre- and Post-Operative Re-Habilitation
edited by
submission deadline 20 Aug 2026 | Viewed by 338 | Submission Open
Keywords: scoliosis; spine; kyphosis; degenerative spine; spine surgery
(This special issue belongs to the Section Orthopedics)
Integrated Ozone Therapy and Physical Rehabilitation for Musculoskeletal Disorders: A Comprehensive Approach submission deadline 20 Aug 2026 | Viewed by 336 | Submission Open
Keywords: ozone therapy; physical rehabilitation; musculoskeletal disorders; integrative medicine; rehabilitation therapy; regenerative medicine; clinical outcomes
(This special issue belongs to the Section Clinical Rehabilitation)
Novel Approaches in Obsessive–Compulsive and Related Spectrum Disorders
edited by and Andrea D. Guastello
submission deadline 20 Aug 2026 | Viewed by 334 | Submission Open
Keywords: OCD; misophonia; hoarding; tic disorders; assessment; treatment
(This special issue belongs to the Section Mental Health)
The Liver–Kidney Axis in Metabolic Diseases: Biomarkers and Clinical Implications
edited by
submission deadline 20 Aug 2026 | Viewed by 333 | Submission Open
Keywords: liver; kidney; cross-organ crosstalk; mechanisms; biomarkers; metabolic diseases; clinical implications
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Updates on Embolization and Embolotherapy for Benign Prostatic Hyperplasia and Men’s Health
edited by Sandeep L. Bagla, Ari J. Isaacson and Abin Sajan
submission deadline 20 Aug 2026 | Viewed by 325 | Submission Open
Keywords: benign prostatic hyperplasia; prostatic artery embolization; men’s health; lower urinary tract symptoms; embolization therapy; radiation safety; prostate cancer and radiotherapy
(This special issue belongs to the Section Nephrology & Urology)
Clinical Advances and Perspectives in Neuro-Oncology
edited by Mariko Sato and
submission deadline 20 Aug 2026 | Viewed by 325 | Submission Open
Keywords: neuro-oncology; diagnosis; treatment; minimally invasive surgery; skull base surgery; brain tumor; radiosurgery; neuro endoscopy
(This special issue belongs to the Section Clinical Neurology)
Bleeding and Thrombotic Complications in Patients with Premalignant Hematologic Conditions: Diagnostic and Therapeutic Challenges
edited by Vasiliki Gkalea and Despina Fotiou
submission deadline 20 Aug 2026 | Viewed by 319 | Submission Open
Keywords: bleeding; thrombosis; hematologic malignancies; premalignant hematologic conditions; clonal hematopoiesis of indeterminate potential (CHIP); clonal cytopenias of undetermined significance (CCUS); monoclonal gammopathy of undetermined significance (MGUS); monoclonal B-cell lymphocytosis (MBL); monoclonal gammopathy of thrombotic significance (MGTS); VITT-like MGTS
(This special issue belongs to the Section Hematology)
Current Trends and Innovations in Coronary Artery Disease and Myocardial Ischemia: Second Edition
edited by
submission deadline 20 Aug 2026 | Viewed by 311 | Submission Open
Keywords: coronary artery disease; fractional flow reserve; invasive coronary angiography; cardiac CT; cardiac MRI
(This special issue belongs to the Section Cardiovascular Medicine)
Personalised and Precision Pharmacotherapy: Data-Driven Therapeutic Optimisation in Real-World Clinical Practice submission deadline 20 Aug 2026 | Viewed by 299 | Submission Open
Keywords: precision pharmacotherapy; personalised medicine ; pharmacokinetics and pharmacodynamics ; therapeutic drug ; monitoring real-world evidence ; multimorbidity ; medication appropriateness ; model-informed precision dosing; does individualisation; clinical decision support
(This special issue belongs to the Section Pharmacology)
Advances in Diagnosis, Monitoring, and Treatment of Myocardial Infarction
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 295 | Submission Open
Keywords: myocardial infarction (MI); occlusion myocardial infarction (OMI); myocardial infarction with non-obstructive coronary arteries (MINOCA); diagnosis; monitoring; treatment
(This special issue belongs to the Section Cardiovascular Medicine)
Managing Chronic Kidney Disease: Current Practices and Future Perspectives
edited by Maria L. Gonzalez-Suarez
submission deadline 20 Aug 2026 | Viewed by 289 | Submission Open
Keywords: chronic kidney disease; diabetic kidney disease; kidney failure; guideline-directed therapies; SLGT 2 inhibitors; GLP1 receptor agonists
(This special issue belongs to the Section Nephrology & Urology)
Clinical Approaches of Intracranial Aneurysm and Subarachnoid Hemorrhage
edited by Sylvia Bele
submission deadline 20 Aug 2026 | Viewed by 286 | Submission Open
Keywords: aSAH; clipping or coiling; extracranial complications; cerebral vasospasm; ICU treatment
(This special issue belongs to the Section Clinical Neurology)
From Histology to Clinical Immunology: Integrated Diagnosis in Oral and Maxillofacial Diseases
edited by Fabiana Nicita
submission deadline 20 Aug 2026 | Viewed by 281 | Submission Open
Keywords: clinical immunology; histology; immunopathology; immune-mediated oral disease; biomarkers
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Advances in Diagnosis and Treatment of Metastatic Spinal Tumor
edited by
submission deadline 20 Aug 2026 | Viewed by 278 | Submission Open
Keywords: metastatic spinal tumors; spine surgery; bone metastasis; imaging diagnosis; minimally invasive surgery; decompression surgery; fixation surgery; emergency surgery; prognosis prediction; elderly patients; nutrition; mental health
(This special issue belongs to the Section Oncology)
Recent Clinical Perspectives on Chronic Kidney Disease
edited by Luca Visconti
submission deadline 20 Aug 2026 | Viewed by 272 | Submission Open
Keywords: chronic kidney disease; nephrology; hemodialysis; renal impairment; renal replacement therapy; new therapeutic approaches in CKD; clinical trials; renal complications
(This special issue belongs to the Section Nephrology & Urology)
Targeting Extravalvular Burden Associated with Valvular Heart Disease
edited by
submission deadline 20 Aug 2026 | Viewed by 269 | Submission Open
Keywords: valvular heart disease; systemic disorder; extravalvular burden; valve dysfunction; valve intervention; multimodality imaging
(This special issue belongs to the Section Cardiology)
Therapeutic Advances and Emerging Treatments in Inflammatory Bowel Disease
edited by
submission deadline 20 Aug 2026 | Viewed by 269 | Submission Open
Keywords: inflammatory bowel disease; therapeutic advances emerging treatments; biologics and small molecules; precision medicine in IBD; pharmacokinetic model
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Recent Advances in Hypercholesterolemia
edited by Ana Catarina Alves
submission deadline 20 Aug 2026 | Viewed by 258 | Submission Open
Keywords: hypercholesterolemia; cardiovascular risk; molecular diagnostics; variants of uncertain significance (VUS); functional characterisation; precision medicine; lipid-lowering therapy
(This special issue belongs to the Section Endocrinology & Metabolism)
Pancreatic Cancer: Novel Strategies of Diagnosis and Treatment submission deadline 21 Aug 2026 | 3 articles | Viewed by 6723 | Submission Open
Keywords: pancreatic cancer; chronic pancreatitis; pancreatic intraepithelial neoplasia; gastroenterology; clinical innovative diagnostic; clinical treatment strategies
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Outcomes of Glaucoma Surgery: Visual Acuity, Effectiveness and Quality of Life submission deadline 21 Aug 2026 | 5 articles | Viewed by 3451 | Submission Open
Keywords: glaucoma surgery; visual acuity; intraocular pressure; surgical outcomes; trabeculectomy; microinvasive glaucoma surgery; postoperative complications; functional vision
(This special issue belongs to the Section Ophthalmology)
Personalized Modern Oncological Strategies for Breast Cancer Treatment
edited by Vlad Alexandru Gata, Maximilian Muntean and
submission deadline 22 Aug 2026 | 5 articles | Viewed by 4083 | Submission Open
Keywords: breast cancer; targeted and immune therapies; predictive biomarkers; surgical de-escalation; MRI of the breast; breast reconstruction
(This special issue belongs to the Section General Surgery)
Advances in Plastic and Reconstructive and Aesthetic Surgery of Face, Breast and Body
edited by
submission deadline 24 Aug 2026 | 6 articles | Viewed by 20178 | Submission Open
Keywords: reconstructive surgery; academic plastic surgery; research; social media in plastic surgery; breast surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Advancements in Cardiomyopathies: Diagnosis, Treatment and Management—2nd Edition submission deadline 24 Aug 2026 | 5 articles | Viewed by 11398 | Submission Open
Keywords: cardiomyopathies; multimodality imaging; cardiac magnetic resonance; genetic testing; cardiogenetics; genetic cardiovascular disease; rare cardiovascular diseases; risk stratification; genotype–phenotype correlations; rare variant interpretation; arrhythmias
(This special issue belongs to the Section Cardiology)
Clinical Advances in Head and Neck Cancer Diagnostics and Treatment
edited by and Alice L. Tang
submission deadline 24 Aug 2026 | 1 articles | Viewed by 1553 | Submission Open
Keywords: head and neck; reconstruction; free flap; surgical margin; biomarker; human papillomavirus (HPV); extranodal extension; immunotherapy; virtual surgical planning
(This special issue belongs to the Section Otolaryngology)
Interventional and Surgical Treatment of Acute and Chronic Pancreatitis
edited by Chirag Desai
submission deadline 25 Aug 2026 | 6 articles | Viewed by 22216 | Submission Open
Keywords: pancreatitis treatment; endoscopic treatment; pancreatic surgery; Whipple; distal pancreatectomy; islet cell auto trans-plant; total pancreatectomy; TPIAT; laparoscopic treatment of pancreatitis; robotic surgery for pancreatitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Alcohol-Related Liver Disease: Diagnosis, Treatment, and Management submission deadline 25 Aug 2026 | 5 articles | Viewed by 16181 | Submission Open
Keywords: alcohol-related liver disease; gut–liver axis; hepatic fibrosis; liver cirrhosis; micro-RNA; inflammatory pathways; liver transplantation; steatohepatitis; fecal microbiota transplantation in liver cirrhosis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Periodontal Diseases and Systemic Health: Pathogenesis, Prevention and Management
edited by
submission deadline 25 Aug 2026 | 8 articles | Viewed by 12713 | Submission Open
Keywords: periodontitis; dental implants; systemic inflammation; diabetes and periodontal disease; cardiovascular implications; pregnancy and oral health; host immune responses; preventive dentistry; implant-prosthetic rehabilitation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Advances in the Management of Cardiac Amyloidosis and Hypertrophic Cardiomyopathy
edited by Ahmed Abuzaid
submission deadline 25 Aug 2026 | 4 articles | Viewed by 10205 | Submission Open
Keywords: cardiac amyloidosis; hypertrophic cardiomyopathy; left ventricular hypertrophy; non-invasive cardiac imaging; heart failure; clinical manifestations
(This special issue belongs to the Section Cardiology)
New Insights into Cardiorenal Metabolic Syndrome
edited by
submission deadline 25 Aug 2026 | 4 articles | Viewed by 9531 | Submission Open
Keywords: cardiorenal medicine; diabetes; chronic renal failure; heart failure; cardiorenal syndrome; nephrocardiology
(This special issue belongs to the Section Cardiovascular Medicine)
Pain Management: Current Challenges and Future Prospects
edited by Gian Marco Petroni
submission deadline 25 Aug 2026 | 5 articles | Viewed by 8496 | Submission Open
Keywords: chronic joint pain; radio frequency ablation; adipose-derived mesenchimal stem cells (ADMScs); intrarticular injection; facet joint injection with ADMScs
(This special issue belongs to the Section Anesthesiology)
Up-to-Date Research in Liver Transplantation
edited by
submission deadline 25 Aug 2026 | 5 articles | Viewed by 6784 | Submission Open
Keywords: liver transplantation; acute or chronic liver diseases; hepatitis C virus infection; hepatocellular carcinoma (HCC); cirrhosis; intrahepatic (ICCA), perihilar (PCCA) cholangiocarcinoma; unresectable liver metastases; acute or chronic liver failure (ACLF); acute alcoholic hepatitis (AAH)
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Current Advances and Future Perspectives of Ischemic Stroke
edited by
submission deadline 25 Aug 2026 | 4 articles | Viewed by 6231 | Submission Open
Keywords: acute ischemic stroke care; neuroimaging in ischemic stroke; alteplase and tenecteplase; endovascular treatments; recanalization and reperfusion; prognostication in stroke patients; blood–brain barrier in ischemic stroke; bi-omarkers in ischemic stroke; omics in stroke
(This special issue belongs to the Section Clinical Neurology)
Recent Advances in Prevention, Management, and Rehabilitation of Head and Neck Injuries
edited by , Pier Enrico Gallenga and
submission deadline 25 Aug 2026 | 3 articles | Viewed by 5933 | Submission Open
Keywords: neck injuries; whiplash injuries; head injuries; concussion; neck pain; cervicalgia; post-concussive syndrome; post-concussive symptoms; vision disorders; hearing disorders; emergency care; emergency therapies; physical medicine and rehabilitation; musculoskeletal rehabilitation; sports medicine
(This special issue belongs to the Section Sports Medicine)
Advances and Updates in Migraine
edited by and Carl H. Göbel
submission deadline 25 Aug 2026 | 6 articles | Viewed by 5249 | Submission Open
Keywords: migraine; chronic migraine; headache disorders; CGRP antibodies; gepants; ditans; triptans; precision medicine; neuromodulation; comorbidities; disability burden; pediatric migraine; ICHD-3 classification; neurotransmitters; preventive therapy; translational headache research
(This special issue belongs to the Section Clinical Neurology)
Shoulder and Elbow Surgery: Clinical Updates and Perspectives
edited by Taku Hatta, Akihiko Hasegawa and Takuma Yuri
submission deadline 25 Aug 2026 | 4 articles | Viewed by 5220 | Submission Open
Keywords: rotator cuff injuries; shoulder arthroplasty; elbow surgery; shoulder surgery; shoulder and elbow disease; arthroscopic surgery; orthopedic surgery
(This special issue belongs to the Section Orthopedics)
New Insights in Cognitive Aging and Mild Cognitive Impairment submission deadline 25 Aug 2026 | 5 articles | Viewed by 4924 | Submission Open
Keywords: cognitive aging; mild cognitive impairment; normative aging; neuropsychological assessment; diagnosis; gerontology; prevention; intervention; multidisciplinary approach; measurement
(This special issue belongs to the Section Geriatric Medicine)
Clinical Diagnosis and Surgical Strategies Update on Ear Disorders: 2nd Edition submission deadline 25 Aug 2026 | 5 articles | Viewed by 4541 | Submission Open
Keywords: middle ear; inner ear; endoscopic ear surgery; cholesteatoma; Menière’s disease; hearing loss; robotic surgery; oto-sclerosis
(This special issue belongs to the Section Otolaryngology)
Helicobacter pylori-Associated Intestinal Diseases and Beyond submission deadline 25 Aug 2026 | 4 articles | Viewed by 4100 | Submission Open
Keywords: IBD; Hp; stomach; celiac disease; diverticulosis; diverticulitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Etiology, Diagnosis, and Management of Upper Gastrointestinal Disorders: 2nd Edition
edited by
submission deadline 25 Aug 2026 | 2 articles | Viewed by 3960 | Submission Open
Keywords: esophagus; stomach; duodenum; DGBI; FGIDs; helicobacter; eosinophilic esophagitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Hidradenitis Suppurativa: Clinical Diagnosis, Treatment, and Management
edited by Piotr K. Krajewski
submission deadline 25 Aug 2026 | 4 articles | Viewed by 3887 | Submission Open
Keywords: hidradenitis suppurativa; acne inversa; clinical diagnosis; disease severity assessment; biologic therapy; surgical management; comorbidities; quality of life; multidisciplinary care; real world evidence
(This special issue belongs to the Section Dermatology)
Hospital-Acquired Infections: Evolving Threats and Epidemiological Insights
edited by
submission deadline 25 Aug 2026 | 4 articles | Viewed by 3437 | Submission Open
Keywords: hospital-acquired infections; healthcare-associated infections; antimicrobial resistance; multidrug-resistant organisms (MDRO); infection prevention and control; outbreak investigation; patient safety; healthcare epidemiology
(This special issue belongs to the Section Infectious Diseases)
Current and Emerging Treatment Options in Chronic Liver Diseases
edited by Chandana B. Herath and Michael Praktiknjo
submission deadline 25 Aug 2026 | 2 articles | Viewed by 2839 | Submission Open
Keywords: liver disease; liver fibrosis; liver cirrhosis; portal hypertension; liver cancer; therapies; immunological therapies for liver cancer; diabetic liver; type 2 diabetes and obesity; spontaneous bacterial peritonitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
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