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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Advances in Non-Trauma Emergency Critical and Resuscitation Medicine

edited by

Sebastian Bergrath

submission deadline 20 Jul 2026 | 1 articles | Viewed by 2314 | Submission Open

Keywords: resuscitation; non-trauma critically ill; emergency department; resuscitation room management; neuro-critical emergency care; emergency department critical care

(This special issue belongs to the Section Emergency Medicine)

Recent Management of Hip Fractures

edited by

Toshiyuki Kawai

submission deadline 20 Jul 2026 | 3 articles | Viewed by 2131 | Submission Open

Keywords: hip fracture; internal fixation; hemiarthroplasty; arthroplasty and fixation; osteoporosis management; fracture prevention; multidisciplinary care; surgical treatment; rehabilitation strategies

(This special issue belongs to the Section Orthopedics)

Clinical Management of Patients Before and After Kidney Transplantation

edited by

Izabela Zakrocka

submission deadline 20 Jul 2026 | 4 articles | Viewed by 2058 | Submission Open

Keywords: chronic kidney disease; kidney function; kidney replacement therapy; kidney transplantation; kidney graft survival; post-transplant complications

(This special issue belongs to the Section Nephrology & Urology)

Clinical Challenges in Heart Failure Management: 2nd Edition

edited by Paolo Severino, Gaetano M. Ruocco and

Andrea D'Amato

submission deadline 20 Jul 2026 | 2 articles | Viewed by 2037 | Submission Open

Keywords: acute heart failure; chronic heart failure; inotropic support; left ventricular assist device; cardiac contractility modulation; guanylate cyclase stimulators; quality of life; telemedicine; palliative care

(This special issue belongs to the Section Cardiology)

Recent Advances and Future Perspectives of Subarachnoid Hemorrhage

edited by Alexandros Doukas and Athanasios K. Petridis

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1980 | Submission Open

Keywords: subarachnoid hemorrhage; neuromonitoring; neurocritical care; neurointerventions; neurointensive care

(This special issue belongs to the Section Clinical Neurology)

Thoracic Surgery Today: Innovations, Challenges, and Future Perspectives

edited by Jeffrey B. Velotta and

Ory Wiesel

submission deadline 20 Jul 2026 | 3 articles | Viewed by 1925 | Submission Open

Keywords: thoracic surgery; minimally invasive thoracic surgery; innovation; esophageal surgery; robotic-assisted thoracic surgery; lung cancer; advanced techniques; thoracic surgical oncology; mediastinal surgery; mesothelioma surgery

(This special issue belongs to the Section General Surgery)

Spine Surgery: Clinical Advances and Practice Updates

edited by

Junho Song

submission deadline 20 Jul 2026 | 2 articles | Viewed by 1925 | Submission Open

Keywords: spine surgery; minimally invasive spine surgery; endoscopic spine surgery; robotics; artificial intelligence; spinal deformity; scoliosis; spinal trauma

(This special issue belongs to the Section Orthopedics)

Clinical Outcomes in Bipolar and Depressive Disorders

edited by

Luca J. Steardo

and Francesco Monaco

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1918 | Submission Open

Keywords: mood disorders; clinical outcomes; treatment response; psychopathology; pathophysiology

(This special issue belongs to the Section Mental Health)

Current Challenges in Adult Congenital Heart Diseases

edited by

Agata Bielecka-Dabrowa

submission deadline 20 Jul 2026 | 3 articles | Viewed by 1838 | Submission Open

Keywords: adult congenital heart disease; quality of life; pregnancy in congenital heart disease; heart failure; arrhythmia; septal defect; congenital valve stenosis; coarctation of the Aorta; Fontan circulation; Tetralogy of Fallot

(This special issue belongs to the Section Cardiology)

Pulmonary Disease and Comorbidities, Clinical and Epidemiological Studies: From Neonates to Adults

edited by

Roxana Maria Nemes

submission deadline 20 Jul 2026 | 3 articles | Viewed by 1775 | Submission Open

Keywords: pulmonary disorders; comorbidity; neonatal lung disease; pediatric pulmonology; adult respiratory disease; chronic respiratory conditions; clinical epidemiology; pulmonary function testing; diagnostic imaging; lung biomarkers; risk factors

(This special issue belongs to the Section Respiratory Medicine)

Early Diagnosis and Treatment of Hepatitis B and C: Bridging Innovation and Implementation

edited by

Rawi Hazzan

and

Fadi Abu Baker

submission deadline 20 Jul 2026 | 2 articles | Viewed by 1767 | Submission Open

Keywords: hepatitis B virus (HBV); hepatitis C virus (HCV); hepatitis delta virus (HDV); early diagnosis; viral hepatitis elimination; functional cure; direct-acting antivirals (DAAs); antiviral therapy; treatment adherence; care cascade; screening programs; health policy

(This special issue belongs to the Section Infectious Diseases)

Echocardiography in Clinical Cardiac Imaging: Advances and Emerging Applications

edited by

Marina Leitman

submission deadline 20 Jul 2026 | 2 articles | Viewed by 1756 | Submission Open

Keywords: echocardiography; cardiac Imaging; speckle-tracking echocardiography; artificial intelligence; myocardial function; valvular heart disease; precision cardiology

(This special issue belongs to the Section Cardiology)

Advances in Clinical Management of Temporomandibular Joint Diseases

edited by

João Luiz Monteiro

submission deadline 20 Jul 2026 | 2 articles | Viewed by 1633 | Submission Open

Keywords: minimally invasive surgical procedure; artificial intelligence; temporomandibular joint disorders; temporomandibular disorders; temporomandibular joint

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Cardiopulmonary Resuscitation in the Emergency Care Unit

edited by

Martín Otero-Agra

, Felipe Fernández-Méndez,

Myriam Santos-Folgar

and

María Fernández-Méndez

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1434 | Submission Open

Keywords: cardiopulmonary resuscitation; advanced life support; new technologies; special circumstances; emergency care unit

(This special issue belongs to the Section Emergency Medicine)

Current Updates on Pediatric Neurological Disorders and Neurorehabilitation

edited by

Lidia Perenc

and

Justyna Podgórska-Bednarz

submission deadline 20 Jul 2026 | 2 articles | Viewed by 1394 | Submission Open

Keywords: child neurological disorders; neurorehabilitation; neurogenetics; treatment; quality of life; rehabilitation teams; congenital brain disorders; trauma; movement disorders; cerebral palsy

(This special issue belongs to the Section Clinical Pediatrics)

The Wide World of Antinuclear Antibodies (ANA)-Associated Disorders: Patterns, Clinical Phenotypes, Comorbidities, and Impact

edited by

Daniela Opris-Belinski

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1389 | Submission Open

Keywords: antinuclear antibodies (ANA); ANA-associated disorders; clinical phenotypes; ANA patterns; lupus, Sjögren’s disease, systemic sclerosis, idiopathic inflammatory myopathies, comorbidities; connective tissue diseases; overlap syndromes; undifferentiated connective tissue disease; risk stratification; patient-centered management

(This special issue belongs to the Section Immunology & Rheumatology)

Novel Perspectives in Transcatheter Aortic Valve Implantation

edited by Nay Min Htun

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1376 | Submission Open

Keywords: TAVI; life-time management; TAVI-in-TAVI; bicuspid valve; pure aortic regurgitation; small annuli

(This special issue belongs to the Section Cardiology)

Beyond the Kidney: Managing Chronic Kidney Disease in the Era of Cardio-Metabolic-Kidney Syndrome

edited by

Maria Amicone

and

Antonio Pisani

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1375 | Submission Open

Keywords: chronic kidney disease; disease-modifying therapy; physical exercise; cardio-metabolic-kidney syndrome; SGLT2 in-hibitors; MRA; renal nutrition; innovative therapies; low protein diet

(This special issue belongs to the Section Nephrology & Urology)

Minimally Invasive Spine Surgery: Evidence, Advances and Controversies

edited by

Miltiadis Georgiopoulos

, Constantine Constantoyannis,

Mark A. MacLean

and Oliver Lasry

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1365 | Submission Open

Keywords: spine surgery; minimally invasive; MIS; MISS; endoscopic; tubular; fusion; laminectomy; discectomy; decompression; percutaneous; robotic; robotic-assisted; navigation; augmented-reality

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Lower Limb Trauma and Orthopedic Surgery: From Bench to Bedside

edited by

Se Won Lee

and

Jihyo Hwang

submission deadline 20 Jul 2026 | 3 articles | Viewed by 1354 | Submission Open

Keywords: lower limb trauma; fracture fixation; arthroplasty; biomechanics; orthopaedic surgery; clin-ical outcomes; minimally invasive techniques; rehabilitation

(This special issue belongs to the Section Orthopedics)

Current Measures for Diagnosis, Monitoring, and Outcome Assessment in Orthopedics, Traumatology, and Hand Surgery, 2nd Edition

edited by

Paweł Reichert

and

Piotr Morasiewicz

submission deadline 20 Jul 2026 | 2 articles | Viewed by 1319 | Submission Open

Keywords: clinical evaluation; hand surgery; orthopaedics; performance-based measures; physical examination; reliability; traumatology

(This special issue belongs to the Section Orthopedics)

Cardiac Imaging: Emerging Techniques and Clinical Applications

edited by

Athanasios Frydas

and

Daniel A. Morris

submission deadline 20 Jul 2026 | 2 articles | Viewed by 1282 | Submission Open

Keywords: 3D echocardiography; myocardial strain; artificial intelligence; automated quantification; cardiac MRI; cardiac CT; multimodality imaging; machine learning; image-based risk stratification; precision cardiology

(This special issue belongs to the Section Cardiology)

Current Status and Future of Urological Surgery

edited by

Filippo Marino

, Davide De Marchi and

Luca Di Gianfrancesco

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1221 | Submission Open

Keywords: urological surgery; robotic-assisted surgery; minimally invasive surgery; artificial intelligence; augmented reality; surgical navigation; endourology; laparoscopic urology; reconstructive urology; functional urology; bph treatment; urinary incontinence; prostate cancer surgery; bladder cancer surgery; surgical innovation; digital surgery

(This special issue belongs to the Section Nephrology & Urology)

Orthodontics: Current Management and Future Options

edited by Arūnas Vasiliauskas and Aistė Kavaliauskienė

submission deadline 20 Jul 2026 | 2 articles | Viewed by 1134 | Submission Open

Keywords: digital orthodontics; clear aligner therapy; accelerated tooth movement; micro-implants; artificial intelligence; patient-centred outcomes; treatment efficiency

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Misconceptions and Myths in Dermatology: From Clinic to Clarity

edited by Simon M. Mueller and Oliver Brandt

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1131 | Submission Open

Keywords: misconceptions; misunderstanding; myths; errors; mistakes; skin; dermatology

(This special issue belongs to the Section Dermatology)

Orthodontic Treatment in Clinical Practice: Strategies for Achieving Optimal Outcomes

edited by Adith Venugopal

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1120 | Submission Open

Keywords: orthodontics; biomechanics; tooth movement; bone remodeling; malocclusions; smile

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Application of Digital Transformation in Ophthalmology

edited by

Eisuke Shimizu

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1039 | Submission Open

Keywords: clinical application; ocular diseases; artificial intelligence (AI); machine learning/ deep learning; smart ophthalmology

(This special issue belongs to the Section Ophthalmology)

Challenges and Solutions in Geriatric Fracture

edited by Detlef Van der Velde and

Henk Jan Schuijt

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1002 | Submission Open

Keywords: geriatric; fracture; frailty; hip fracture; comorbidity; perioperative optimization; orthogeriatrics; rehabilitation; shared decision-making; postoperative outcomes; mortality and morbidity; functional recovery; multidisciplinary care; quality of life; recovery; mobility; palliative care

(This special issue belongs to the Section Geriatric Medicine)

Dental Care and Oral Health in Adolescents and Children

edited by

Karolina Gerreth

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1000 | Submission Open

Keywords: oral health; oral diseases; diagnosis; dental treatment; treatment methods; general health; pediatric dentistry; special care dentistry; immunodeficiency; pediatric dental surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Management of Diabetes-Related Cardiovascular Disease: Current Treatment and Future Options

edited by Antonio J. Amor and Tonet Serés-Noriega

submission deadline 20 Jul 2026 | 1 articles | Viewed by 974 | Submission Open

Keywords: type 1 diabetes; type 2 diabetes; cardiovascular disease; biomarkers; atherosclerosis; cardioprotective drugs; vascular ultrasound

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Outcomes in Lumbar Spinal Stenosis Treatment

edited by Rafał Staszkiewicz and

Beniamin Oskar Grabarek

submission deadline 20 Jul 2026 | 2 articles | Viewed by 970 | Submission Open

Keywords: lumbar spinal stenosis; clinical outcomes; decompression surgery; conservative management; molecular biomarkers; inflammation and fibrosis; neurotrophic factors; personalized medicine; siganling pathways; quality of life

(This special issue belongs to the Section Orthopedics)

Gynecologic Cancers: Current Clinical Management and Multidisciplinary Treatment Strategies

edited by

Iason Psilopatis

and

Christos Damaskos

submission deadline 20 Jul 2026 | 1 articles | Viewed by 959 | Submission Open

Keywords: gynecologic; cancer; uterus; ovarian; endometrial; cervical

(This special issue belongs to the Section Obstetrics & Gynecology)

Perspectives in Bionic Reconstruction and Post-Amputation Management

edited by

Alexander Gardetto

and Jennifer Ernst

submission deadline 20 Jul 2026 | 2 articles | Viewed by 955 | Submission Open

Keywords: bionic reconstruction; advanced prosthetics; neurorehabilitation; sensory feedback; motor control

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Clinical Implications of Artificial Intelligence in Patient Care

edited by

Safa Elkefi

and

Luigi Lavorgna

submission deadline 20 Jul 2026 | 1 articles | Viewed by 941 | Submission Open

Keywords: artificial intelligence; clinical decision support; human factors; digital health; patient care; implementation science; medical informatics; trust in AI

(This special issue belongs to the Section Clinical Research Methods)

Clinical Update on Aortic Valve Disease Treatments

edited by

Giovanni Concistre

submission deadline 20 Jul 2026 | 1 articles | Viewed by 935 | Submission Open

Keywords: aortic valve disease; minimally invasive surgery; transcatheter procedures; echocardiography; diagnosis; therapy; innovation

(This special issue belongs to the Section Cardiology)

Pulmonary Hypertension and Chronic Lung Disease: Diagnosis and Management

edited by

Josep Montserrat-Capdevila

and

Emmanuel E. Egom

submission deadline 20 Jul 2026 | 1 articles | Viewed by 882 | Submission Open

Keywords: pulmonary hypertension; chronic obstructive pulmonary disease (COPD); chronic lung disease; epidemiology; exacerbations; comorbidities; risk factors; diabetes; systemic inflammation; real-world data

(This special issue belongs to the Section Respiratory Medicine)

Novel Research in Cardiovascular Imaging

edited by Stanciu Silviu and

Lucia Agoston-Coldea

submission deadline 20 Jul 2026 | 1 articles | Viewed by 877 | Submission Open

Keywords: echocardiography; cardiac CT; CMR; nuclear medicine; artificial intelligence

(This special issue belongs to the Section Cardiovascular Medicine)

Optimizing Radiotherapy in Clinical Practice: Innovation and Outcomes

edited by

Sarah Han-Oh

, Senthamizhchelvan Srinivasan and Joseph Moore

submission deadline 20 Jul 2026 | 1 articles | Viewed by 863 | Submission Open

Keywords: AI-assisted automated contouring and planning; AI-assisted quality assurance; AI-assisted safety and quality improvement; radiotherapy automation; radiomics; radiotherapy error detection; personalized radiopharmaceutical therapy; theranostics; online adaptive radiotherapy; real-time treatment adaptation; image-guided radiotherapy (IGRT); AI-assisted online adaptation; personalized radiotherapy; cone-beam CT adaptation

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Therapeutic Advances in Hematological Malignancies: New Breakthroughs and Future Directions

edited by Seema Naik

submission deadline 20 Jul 2026 | 2 articles | Viewed by 848 | Submission Open

Keywords: leukemia; lymphoma; myeloma; cell therapy; targeted therapy

(This special issue belongs to the Section Hematology)

Hypertrophic Cardiomyopathy: New Insights into Complications and Treatment

edited by Ilaria Dentamaro and Ciro Santoro

submission deadline 20 Jul 2026 | 1 articles | Viewed by 844 | Submission Open

Keywords: hypertrophic cardiomyopathy; complications; risk stratification; multimodality imaging; myosin inhibitors; precision medicine

(This special issue belongs to the Section Cardiology)

Updates on Reconstructive Urology

edited by

Fabio Campodonico

submission deadline 20 Jul 2026 | 1 articles | Viewed by 830 | Submission Open

Keywords: reconstructive urology; urethral stenosis; urethroplasty; urethral diverticulum; ureteral stenosis; male incontinence; urinary diversion; hypospadias; microsurgery; experimental microsurgery; bladder diverticulum; neobladder

(This special issue belongs to the Section Nephrology & Urology)

Pneumonia: From Diagnosis to Treatment

edited by

Marie Carmen Valenza

Laura López-López

and

María Granados Santiago

submission deadline 20 Jul 2026 | 1 articles | Viewed by 812 | Submission Open

Keywords: pneumonia; diagnosis; treatment; multidisciplinary care; pulmonary rehabilitation

(This special issue belongs to the Section Respiratory Medicine)

Current Concepts in Melanoma: Innovations in Early Detection, Prognosis and Management

edited by Babar Khan Rao

submission deadline 20 Jul 2026 | 1 articles | Viewed by 785 | Submission Open

Keywords: melanoma; early detection; non-invasive diagnostic innovations; artificial intelligence-assisted diagnosis; melanoma management

(This special issue belongs to the Section Dermatology)

Exercise for Healthy Aging: Clinical Physiology, Functional Outcomes, and Implications for Clinical Practice

edited by

Jerónimo Aragón-Vela

and

Rafael A. Casuso

submission deadline 20 Jul 2026 | 1 articles | Viewed by 774 | Submission Open

Keywords: exercise; healthy aging; functional independence; mitochondrial adaptations; physical activity interventions; neuromuscular function; cardiorespiratory fitness; metabolic health; biomarkers of aging

(This special issue belongs to the Section Sports Medicine)

Clinical Updates and Current Challenges in Obstetrical Anesthesia

edited by Michael Froelich

submission deadline 20 Jul 2026 | Viewed by 758 | Submission Open

Keywords: obstetrical anesthesia; clinical innovation; practice guidelines; neuraxial techniques; enhanced recovery; risk stratification; maternal safety; multimodal analgesia; health systems innovation; global and low-resource care

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Advances, Opportunities, and Challenges in Digestive Diseases of the Foregut

edited by Valentin Mocanu and

Salvador Navarrete

submission deadline 20 Jul 2026 | 1 articles | Viewed by 755 | Submission Open

Keywords: obesity; achalasia; reflux; malrotation; therapeutic endoscopy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

New Insights in Trauma and Emergency Surgery

edited by Kai Oliver Jensen and Valentin Neuhaus

submission deadline 20 Jul 2026 | 1 articles | Viewed by 697 | Submission Open

Keywords: trauma and emergency surgery; multiple trauma; orthopedic trauma; surgery; concepts in trauma

(This special issue belongs to the Section Emergency Medicine)

Current Therapeutic Approaches to Addictive Disorders

edited by Linda Haddad

submission deadline 20 Jul 2026 | 1 articles | Viewed by 695 | Submission Open

Keywords: addiction treatment; dependence; withdrawal management; relapse prevention; recovery; rehabilitation and support

(This special issue belongs to the Section Mental Health)

What We See Through Cardiac Imaging: Second Edition

edited by

Valeria Pergola

and

Francesca Mantovani

submission deadline 20 Jul 2026 | 1 articles | Viewed by 689 | Submission Open

Keywords: cardiomyopathies; multimodality imaging; echocardiography; cardiac-computed tomography; cardiac magnetic resonance; prognosis; arrhythmias; heart failure

(This special issue belongs to the Section Cardiology)

Preventive Strategies and Novel Treatments for Rheumatoid Arthritis

edited by

Vincent Goeb

submission deadline 20 Jul 2026 | 1 articles | Viewed by 665 | Submission Open

Keywords: rheumatoid arthritis; antibodies; biologics; JAK; environment; susceptibility; therapeutic strategies

(This special issue belongs to the Section Immunology & Rheumatology)

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