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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Advances and Challenges in Vascular and Endovascular Medicine

edited by Luca Bertoglio

submission deadline 31 Jul 2025 | 7 articles | Viewed by 9857 | Submission Open

Keywords: vascular and endovascular medicine; minimally invasive cardiovascular surgery; vascular diseases; endovascular technologies; endovascular surgery; aortic dissection

(This special issue belongs to the Section Vascular Medicine)

Vascular Surgery: Current Status and Future Perspectives

edited by Murray L. Shames and Adam Tanious

submission deadline 31 Jul 2025 | 4 articles | Viewed by 9597 | Submission Open

Keywords: vascular history; peripheral arterial disease; aortic aneurysm; aortic dissection; carotid disease

(This special issue belongs to the Section Vascular Medicine)

Clinical Advances in Endoscopic Ultrasound-Guided Diagnosis and Treatment

edited by Nicola Muscatiello

submission deadline 31 Jul 2025 | 5 articles | Viewed by 8743 | Submission Open

Keywords: endoscopic ultrasound (EUS); pancreas; cancer; lumen apposing metal stent (LAMS); stent

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Orthopedic Surgery: Latest Advances and Future Prospects

edited by Andrea Marinozzi and

Biagio Zampogna

submission deadline 31 Jul 2025 | 5 articles | Viewed by 8303 | Submission Open

Keywords: custom-made; regenerative; prosthetic; noninvasive surgery; robotic surgery; percutaneous surgery; minimally invasive surgery

(This special issue belongs to the Section Orthopedics)

Oral and Maxillofacial Surgery: Current Updates and Perspectives

edited by

Alessandro Antonelli

submission deadline 31 Jul 2025 | 5 articles | Viewed by 8029 | Submission Open

Keywords: current updates in oral and maxillofacial surgery; new insights in oral medicine; advances in dental implantology; 3D pre-surgical evaluation in oral and maxillofacial surgery; regenerative dentistry

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Endoscopic Techniques in Digestive and Gynecological Diseases

edited by

Miguel Mascarenhas

, Teresa Mascarenhas and

Guilherme Macedo

submission deadline 31 Jul 2025 | 3 articles | Viewed by 7814 | Submission Open

Keywords: endoscopy; gastroenterology; gynecology; colonoscopy; colposcopy; artificial intelligence; capsule endoscopy; upper endoscopy; hysteroscopy; pancreatobiliary endoscopy

(This special issue belongs to the Section General Surgery)

Female Infertility: Clinical Diagnosis and Treatment

edited by

Laurie Henry

submission deadline 31 Jul 2025 | 7 articles | Viewed by 6658 | Submission Open

Keywords: infertility; assisted reproductive techniques; diagnosis; implantation; gametes

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Challenges in Clinical Dentistry: 2nd Edition

edited by

Eiji Tanaka

and

Susumu Abe

submission deadline 31 Jul 2025 | 4 articles | Viewed by 6142 | Submission Open

Keywords: AI; clinical dentistry; epidemiology; geriatric dentistry; dental technology; dental material; challenging hypothesis; preventive dentistry; sleep medicine; digital dentistry; smart dentistry; stomatognathic function

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Advances in Cardiothoracic Anesthesia

edited by Eleni Arnaoutoglou and Metaxia V. Bareka

submission deadline 31 Jul 2025 | 5 articles | Viewed by 5925 | Submission Open

Keywords: cardiac anesthesia; perioperative medicine; outcome; regional anesthesia; novel pharmacological agents; minimally invasive surgical methods; enhanced recovery; patient safety

(This special issue belongs to the Section Anesthesiology)

Clinical Advances in Reconstructive Surgery: Innovations and Outcomes for Improved Patient Care

edited by Rami S. Kantar

submission deadline 31 Jul 2025 | 5 articles | Viewed by 5743 | Submission Open

Keywords: reconstructive surgery; clinical advances; innovations; surgical outcomes; patient care; cleft lip repair; breast reconstruction; facial reconstruction; hand surgery; burn reconstruction; minimally invasive procedures; patient-specific treatment planning; anesthesia and pain management; regenerative medicine

(This special issue belongs to the Section General Surgery)

Emerging Treatment Options for Skull Base Tumors and Related Diseases

edited by

Matteo Zoli

submission deadline 31 Jul 2025 | 4 articles | Viewed by 5441 | Submission Open

Keywords: neurosurgery; skull base tumors; minimally invasive approaches; neuro-oncology; endoscopic endonasal surgery

(This special issue belongs to the Section Oncology)

Advanced Strategies and Innovations to Enhance Outcomes in Cardiac Ablation

edited by

Nikolaos K. Fragakis

and

Paschalis Karakasis

submission deadline 31 Jul 2025 | 3 articles | Viewed by 5345 | Submission Open

Keywords: arrhythmias; cardiac ablation; catheter technology; imaging; anticoagulation optimization; post-procedure care

(This special issue belongs to the Section Cardiology)

Advances in the Diagnosis, Treatment, and Prognosis of Aortic Stenosis

edited by Rita Milewski

submission deadline 31 Jul 2025 | 4 articles | Viewed by 4722 | Submission Open

Keywords: aortic valve stenosis; aortic valve replacement; surgical aortic valve replacement; transfemoral aortic valve replacement; risk stratification for aortic stenosis

(This special issue belongs to the Section Cardiology)

Personalized Medicine for the Management of Non-Communicable Disease (NCDs)

edited by

Alessandro Mattina

, Giulio Geraci and

Vincenzina Lo Re

submission deadline 31 Jul 2025 | 5 articles | Viewed by 4014 | Submission Open

Keywords: personalized medicine; precision medicine; non-communicable disease; cardiovascular disease; cancer; diabetes; chronic obstructive pulmonary disease; cognitive impairment; atherosclerosis; lipids; inflammation; immunity; therapy

(This special issue belongs to the Section Epidemiology & Public Health)

Hernia Surgery and Postoperative Management

edited by Jacob Rosenberg

submission deadline 31 Jul 2025 | 3 articles | Viewed by 3907 | Submission Open

Keywords: hernia surgery; hernia repair; abdominal hernia; preoperative; intraoperative; postoperative; management; complications

(This special issue belongs to the Section General Surgery)

Clinical Updates on Perioperative Pain Management: 2nd Edition

edited by

Felice Eugenio Agro

Giuseppe Pascarella

and

Fabio Costa

submission deadline 31 Jul 2025 | 5 articles | Viewed by 3860 | Submission Open

Keywords: anesthesia and intensive care; pain management; spinal anesthesia; postoperative pain; breast surgery; fascial plane blocks; abdominal surgery; cardiac surgery; thoracotomy; knee surgery; orthopedic surgery; hip surgery; ultrasound

(This special issue belongs to the Section Anesthesiology)

Recent Advances in Minimally Invasive Gynecologic Surgery (MIGS)

edited by Laurenţiu Cornel Pirtea,

Dominic Iliescu

and Răzvan Ciortea

submission deadline 31 Jul 2025 | 3 articles | Viewed by 3472 | Submission Open

Keywords: laparoscopy; urogynecology; oncologic surgery; minimally invasive surgery

(This special issue belongs to the Section Obstetrics & Gynecology)

Oral and Maxillofacial Surgery—Current Advances and Future Directions

edited by

Sung-Woon On

and

Byoung-Eun Yang

submission deadline 31 Jul 2025 | 4 articles | Viewed by 3452 | Submission Open

Keywords: oral surgery; artificial intelligence; computer-assisted surgery; robotic surgical procedures; printing; three-dimensional; dental implants; orthognathic surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Attention-Deficit/Hyperactivity Disorder (ADHD): Advances in Diagnosis and Treatment

edited by Yanli Zhang-James

submission deadline 31 Jul 2025 | 3 articles | Viewed by 3033 | Submission Open

Keywords: attention-deficit/hyperactivity disorder; neurodevelopmental disorder; hyperactivity; children; adolescents; adult

(This special issue belongs to the Section Clinical Neurology)

Acute Myocardial Infarction: Clinical Advances in Prognostic Stratification, Diagnosis, and Treatment

edited by

Matteo Armillotta

Luca Bergamaschi

and

Carmine Pizzi

submission deadline 31 Jul 2025 | 4 articles | Viewed by 2971 | Submission Open

Keywords: acute myocardial infarction (AMI); atherosclerosis; ST segment elevation myocardial infarction (STEMI); non-ST elevation myocardial infarction (NSTEMI); acute coronary syndrome (ACS); prognosis; coronary CT angiography (CCTA); cardiac magnetic resonance (CMR); reperfusion therapy; antiplatelet therapy

(This special issue belongs to the Section Cardiology)

Innovative Systemic Treatments for Atopic Dermatitis

edited by

Luigi Gargiulo

submission deadline 31 Jul 2025 | 3 articles | Viewed by 2857 | Submission Open

Keywords: atopic dermatitis; atopic eczema; JAK inhibitors; anti-IL-4; anti-IL-13; dupilumab; tralokinumab; lebrikizumab; abrocitinib; upadacitinib; baricitinib

(This special issue belongs to the Section Dermatology)

Cardiac Sarcoidosis: Diagnosis and Emerging Therapeutic Strategies

edited by Raheel Ahmed and Muhammad Rashid

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2688 | Submission Open

Keywords: cardiac sarcoidosis; outcomes; imaging; devices; steroids; immunosuppressants; isolated cardiac sarcoidosis; systemic cardiac sarcoidosis; endomyocardial biopsy; heterogeneity

(This special issue belongs to the Section Cardiovascular Medicine)

Rare Respiratory Diseases: A Personal and a Public Health Problem: 3rd Edition

edited by

Francisco Dasí

submission deadline 31 Jul 2025 | 3 articles | Viewed by 2682 | Submission Open

Keywords: rare diseases; rare respiratory diseases; alpha-1 antitrypsin deficiency; primary ciliary dyskinesia; cystic fibrosis; idiopathic pulmonary fibrosis; lymphangioleiomyomatosis; interstitial lung diseases; pulmonary arterial hypertension

(This special issue belongs to the Section Respiratory Medicine)

Advancements in Optical Diagnostics for Head and Neck: Current Trends and Future Directions

edited by

Waseem Jerjes

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2542 | Submission Open

Keywords: head and neck cancer; head and neck surgery; fluorescence imaging; Raman spectroscopy; optical coherence tomography; photoacoustic imaging; photodiagnosis; photodynamic therapy

(This special issue belongs to the Section Otolaryngology)

Challenges in Minimally Invasive Colorectal and Abdominal Wall Surgery

edited by Francesco Ferrara and

Roberto Peltrini

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2514 | Submission Open

Keywords: colorectal surgery; laparoscopy; abdominal wall surgery; hernia; diastasis recti; surgical oncology; rectal tumor; colon tumor; colorectal neoplasia

(This special issue belongs to the Section General Surgery)

Prevention, Diagnosis and Treatment of Oral Mucosal Diseases

edited by

Masanobu Abe

submission deadline 31 Jul 2025 | 3 articles | Viewed by 2390 | Submission Open

Keywords: oral mucosal diseases; oral mucositis; oral precancerous lesions; oral cancer; oral potentially malignant disorders; OPMDs; oral leukoplakia

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Male Fertility in the Modern Age: Challenges and Opportunities

edited by Angelo Marino

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2345 | Submission Open

Keywords: male infertility; semen parameters; sperm selection; IVF/ICSI

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Advances in Diagnosis, Risk Stratification, and Personalized Management in Acute Coronary Syndromes

edited by Efstratios Karagiannidis, Barbara P. Fyntanidou and Aikaterini Apostolopoulou

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2213 | Submission Open

Keywords: acute coronary syndrome (ACS); cardiovascular disease (CVD); ischemic heart disease; emergency medicine; risk stratification; personalized treatment; antiplatelets; primary and secondary prevention

(This special issue belongs to the Section Cardiology)

Knee Arthroplasty Surgery: Management and Future Opportunities: 2nd Edition

edited by

Joaquín Moya-Angeler

and

Francisco Forriol

submission deadline 31 Jul 2025 | 3 articles | Viewed by 2014 | Submission Open

Keywords: knee; knee replacement; knee arthroplasty; knee alignment technique; robotic knee arthroplasty

(This special issue belongs to the Section Orthopedics)

Clinical Advances in Assessment Measures and Theoretical Models of Caregivers' Sensitivity and Contingency: 2nd Edition

edited by

Silvia Cimino

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1910 | Submission Open

Keywords: clinical caregiving; sensitivity assessment; contingency modeling; caregiver– patient interactions; mental health outcomes; novel assessment measures; therapeutic responsiveness; caregiver interventions; clinical well-being; care recipient support

(This special issue belongs to the Section Intensive Care)

Artificial Intelligence and Machine Learning in Clinical Practice: Advancing Medical Imaging Analysis

edited by Guillaume Herpe

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1702 | Submission Open

Keywords: artificial intelligence; effectiveness; transformative impact; patient-centered radiology; workflows

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Recent Clinical Research on Nonalcoholic Fatty Liver Disease: 2nd Edition

edited by Gerond V. Lake-Bakaar

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1586 | Submission Open

Keywords: NAFLD; NASH; cirrhosis; hepatocellular carcinoma; hepatitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Sustaining Success Through Innovation in Kidney Transplantation

edited by Junji Uchida

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1369 | Submission Open

Keywords: kidney transplantation; long-term graft survival; immunosuppression; organ shortage; post-transplant complication

(This special issue belongs to the Section Nephrology & Urology)

Diagnostic and Therapeutic Pathways in Cardiac Heart Failure

edited by

Vincenzo Ezio Santobuono

and

Andrea Igoren Guaricci

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1290 | Submission Open

Keywords: heart failure; cardiomyopathies; pharmacologic therapies; device therapies; biomarkers; genetic testing; sudden cardiac death; cardiac MRI

(This special issue belongs to the Section Cardiology)

Sports Injuries: Recent Advances in Prevention and Rehabilitation, 2nd Edition

edited by

Stasinopoulos Dimitrios

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1287 | Submission Open

Keywords: sports injuries; treatment; musculoskeletal disorders; rehabilitation; physical rehabilitation; exercise science; sports science; injury prevention

(This special issue belongs to the Section Sports Medicine)

Diagnosis and Treatment of Salivary Gland Tumors: Current Advances and Future Options

edited by

Masaaki Higashino

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1163 | Submission Open

Keywords: salivary gland tumor; facial nerve; functional preservation; preoperative diagnosis; ultrasonography; intraoperative nerve monitoring; extracapsular dissection; endoscopic surgery; neck dissection; facial nerve reconstruction; anticancer therapy; postoperative radiation therapy; frey syndrome; first bite syndrome; rehabilitation

(This special issue belongs to the Section General Surgery)

Clinical Advances in Minimally Invasive Urologic Surgery

edited by

Umberto Carbonara

, Fabio Crocerossa and

Savio Domenico Pandolfo

submission deadline 31 Jul 2025 | 1 articles | Viewed by 820 | Submission Open

Keywords: urology; uro-oncology; uro-gynecology; robotic surgery; laparoscopy; robot-assisted; artificial intelligence

(This special issue belongs to the Section Nephrology & Urology)

Clinical Advances in Autoimmune Disorders

edited by

Chiara Pellicano

and

Edoardo Rosato

submission deadline 31 Jul 2025 | 1 articles | Viewed by 816 | Submission Open

Keywords: systemic sclerosis; Raynaud’ s phenomenon; digital ulcers; scleroderma renal crisis; pulmonary arterial hypertension; interstitial lung disease; fibrosis

(This special issue belongs to the Section Immunology)

Application of Artificial Intelligence in Cardiology

edited by

Matthias Unterhuber

submission deadline 31 Jul 2025 | 1 articles | Viewed by 692 | Submission Open

Keywords: artificial intelligence; cardiology; clinical practice; valvular heart disease; arrhythmias; device therapy; machine learning

(This special issue belongs to the Section Cardiology)

Foot and Ankle Surgery: Current Advances and Prospects

edited by

Jaeho Cho

submission deadline 31 Jul 2025 | 1 articles | Viewed by 687 | Submission Open

Keywords: foot and ankle surgery; foot pathologies; ankle disease and trauma; diabetic foot; epidemiology; clinical anatomy; foot orthoses; weight-bearing CT

(This special issue belongs to the Section Orthopedics)

Clinical Investigations into Diagnosing and Managing Strabismus

edited by Mario Cantó Cerdán and Pilar Cacho-Martínez

submission deadline 31 Jul 2025 | 1 articles | Viewed by 592 | Submission Open

Keywords: oculomotricity; binocular vision; strabismus; ocular motility disorders; exotropia; esotropia; video oculography; eye tracker; ocular deviation

(This special issue belongs to the Section Ophthalmology)

Clinical Insights into Pediatric Critical Care

edited by Katherine Biagas and Daniel E Sloniewsky

submission deadline 31 Jul 2025 | 1 articles | Viewed by 512 | Submission Open

Keywords: PICU; anemia; blood transfusion; critically ill children; traumatic hemorrhage

(This special issue belongs to the Section Intensive Care)

Hip Fracture and Surgery: Clinical Updates and Challenges

edited by

Norio Imai

submission deadline 31 Jul 2025 | 2 articles | Viewed by 406 | Submission Open

Keywords: antiosteoporosis medication; fracture liaison service; osteosynthesis; total hip arthroplasty; hemiarthroplasty

(This special issue belongs to the Section Orthopedics)

Novel Developments on Diagnosis and Treatment of Atrial Fibrillation

edited by

Elena Bobescu

and Mihaela-Viviana Ivan

submission deadline 31 Jul 2025 | 1 articles | Viewed by 326 | Submission Open

Keywords: atrial fibrillation; supraventricular arrhythmia; cardiovascular risk; oxidative stress; inflammation

(This special issue belongs to the Section Cardiovascular Medicine)

Machine Learning and Artificial Intelligence in Neurosurgery

edited by Jan Oliver Neumann and

Paul Naser

submission deadline 31 Jul 2025 | Viewed by 323 | Submission Open

Keywords: artificial intelligence; neurosurgery; neuro-oncology; spinal neurosurgery; neuro-ICU; stereotactic neurosurgery; pre-operative planning

(This special issue belongs to the Section Clinical Neurology)

Kidney Transplantation: Challenges, Advances and Lessons Learnt

edited by Karim Soliman and

Tibor Fülöp

submission deadline 31 Jul 2025 | Viewed by 244 | Submission Open

Keywords: kidney transplantation; nephrology; transplant medicine; patient selection criteria; immunosuppressive treatment; long-term outcomes; graft survival; complication; multi-organ transplant consideration; innovation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Heart Failure and Its Complications: Advances in Clinical Diagnosis and Management, 2nd Edition

edited by

Michael J. Bonios

submission deadline 31 Jul 2025 | Viewed by 216 | Submission Open

Keywords: heart failure; complications; arrhythmias; pharmacological therapy; devices; mechanical circulatory support

(This special issue belongs to the Section Cardiology)

Hand Surgery Clinical Advances and Practice Updates

edited by Guy Rubin

submission deadline 31 Jul 2025 | Viewed by 213 | Submission Open

Keywords: trauma; mallet; burn; nerve; tendon

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Clinical Advances in Treatment for Venous Thromboembolism

edited by

Elisavet Grouzi

and Georgia Kaiafa

submission deadline 31 Jul 2025 | Viewed by 210 | Submission Open

Keywords: venous thromboembolism; anticoagulation; cancer-associated thrombosis; thrombosis in MPNs; thrombosis in multiple myeloma; antiphospholipidic syndrome; thrombosis in PNH; thrombosis in hemoglobinopathies; thrombophilia; pregnancy and thrombophilia; reversal of anticoagulants; thromboprophylaxis

(This special issue belongs to the Section Hematology)

Clinical Management and Treatment of Psoriasis

edited by

Luciano Ibba

submission deadline 31 Jul 2025 | 1 articles | Viewed by 198 | Submission Open

Keywords: psoriasis; biological drugs; personalized medicine; comorbidities; real-world evidence

(This special issue belongs to the Section Dermatology)

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