Clinical Outcomes in Lumbar Spinal Stenosis Treatment
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".
Deadline for manuscript submissions: 20 July 2026
Special Issue Editors
2. Department of Neurosurgery, 5th Military Clinical Hospital with the SP ZOZ Polyclinic in Krakow, 30-901 Krakow, Poland
3. Department of Neurosurgery, Faculty of Medicine in Zabrze, Academy of Silesia, 40-555 Katowice, Poland
Interests: lumbar spinal stenosis; clinical outcomes; decompression surgery; inflammation and fibrosis
Interests: gene expression; epigenetics; drug resistance; cancer; tumor microenvironmental
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Lumbar spinal stenosis (LSS) is a prevalent degenerative condition and a major source of pain, disability, and reduced quality of life in the aging population. Despite advances in diagnostic imaging and surgical techniques, optimal treatment selection and prediction of clinical outcomes remain challenging. This Special Issue invites original research, reviews, and meta-analyses addressing the full spectrum of LSS management—from conservative and pharmacological therapies to minimally invasive and open surgical approaches. We particularly encourage submissions that integrate molecular and cellular perspectives, including studies exploring inflammatory mediators, growth factors, neurotrophins, fibrosis-related pathways, and extracellular matrix remodeling in ligamentum flavum or intervertebral disk degeneration. Clinical research linking biomarkers, genetic or epigenetic factors, and molecular signaling pathways (e.g., TGF-β, MAPK, PI3K/AKT) with clinical or imaging outcomes is especially welcome. Additional topics of interest include rehabilitation strategies, long-term functional recovery, pain modulation, and quality-of-life assessment. Through a multidisciplinary lens bridging clinical and molecular sciences, this Special Issue aims to advance personalized approaches in lumbar spinal stenosis treatment.
Dr. Rafał Staszkiewicz
Prof. Dr. Beniamin Oskar Grabarek
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- lumbar spinal stenosis
- clinical outcomes
- decompression surgery
- conservative management
- molecular biomarkers
- inflammation and fibrosis
- neurotrophic factors
- personalized medicine
- siganling pathways
- quality of life
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
