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Novel Perspectives in Transcatheter Aortic Valve Implantation

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 20 July 2026 | Viewed by 898

Special Issue Editor


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Guest Editor
1. Department of Cardiology, The Alfred Hospital, Melbourne, VIC 30034, Australia
2. Department of Cardiology, Peninsula University Hospital, Melbourne, VIC 3199, Australia
Interests: structural heart interventions; TAVI; transcatheter valve therapies; mitral and tricuspid valve interventions; left atrial appendage closure; complex coronary interventions

Special Issue Information

Dear Colleagues,

Transcatheter Aortic Valve Implantation (TAVI) has revolutionized the way we managed severe aortic stenosis in the last decade. Recently there has been significant progress in various aspects of TAVI, such as valve durability (for example, PARTNER-3 7-year data), intervention timing (for example, the EARLY TAVR trial), etc. The European Society of Cardiology has just updated its guidelines on the management of valvular heart disease.

This Special Issue aims to address remaining challenges in the field of TAVI, focusing on lifetime management of patients with severe aortic stenosis, TAVI in bicuspid aortic valve disease, TAVI in small annuli, TAVI-in-TAVI, and transcatheter valve therapy in pure aortic regurgitation.

Dr. Nay Min Htun
Guest Editor

Manuscript Submission Information

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Keywords

  • TAVI
  • life-time management
  • TAVI-in-TAVI
  • bicuspid valve
  • pure aortic regurgitation
  • small annuli

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Published Papers (1 paper)

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Review

23 pages, 1333 KB  
Review
Lifetime Management of Transcatheter Aortic Valve Replacement: A Guide to Decision-Making and Future Reinterventions
by Malanka Lankaputhra, Dion Stub, Riley J. Batchelor, Vishal Goel and Nay Min Htun
J. Clin. Med. 2026, 15(5), 1917; https://doi.org/10.3390/jcm15051917 - 3 Mar 2026
Viewed by 691
Abstract
Transcatheter aortic valve replacement (TAVR) has revolutionized the treatment of severe aortic stenosis, evolving from a therapy reserved for inoperable patients to a first-line option across all surgical risk categories. As TAVR expands to younger patients with longer life expectancies, lifetime management strategies [...] Read more.
Transcatheter aortic valve replacement (TAVR) has revolutionized the treatment of severe aortic stenosis, evolving from a therapy reserved for inoperable patients to a first-line option across all surgical risk categories. As TAVR expands to younger patients with longer life expectancies, lifetime management strategies become paramount. This comprehensive review examines the important role of computed tomography (CT) planning in optimizing initial valve selection and predicting future reintervention feasibility. We discuss the decision framework between TAVR and surgical aortic valve replacement (SAVR) as initial therapy, strategies to optimize the index TAVR procedure, including minimizing patient-prosthesis mismatch, reducing paravalvular regurgitation, preventing conduction abnormalities and coronary obstruction, and facilitating future reinterventions. For patients requiring redo procedures, we analyse TAVR-in-TAVR considerations, including risk plane assessment, coronary access preservation, and leaflet modification techniques. Future directions include advances in valve design, artificial intelligence integration in procedural planning, and development of personalized risk assessment tools. Successful lifetime management requires multidisciplinary collaboration and individualized treatment planning to optimize outcomes throughout a patient’s lifetime journey with aortic valve disease. Full article
(This article belongs to the Special Issue Novel Perspectives in Transcatheter Aortic Valve Implantation)
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