Clinical Outcomes in Bipolar and Depressive Disorders
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Mental Health".
Deadline for manuscript submissions: 30 January 2026 | Viewed by 23
Special Issue Editors
Interests: bipolar disorder; lithium; psychopharmacology; sleep disturbance; high risk; mood disorders; psychological trauma
Special Issues, Collections and Topics in MDPI journals
2. European Biomedical Research Institute of Salerno (EBRIS), Salerno, Italy
Interests: schizophrenia; depression
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The Special Issue “Clinical Outcomes in Bipolar and Depressive Disorders” aims to gather high-quality contributions exploring the complex interplay between clinical pathophysiological mechanisms, clinical phenomenology, and treatment outcomes in mood disorders. Bipolar and depressive disorders represent a major global burden, with substantial personal, social, and economic consequences. Despite advances in diagnostic frameworks and therapeutic options, heterogeneity in clinical presentation and variability in treatment response remain critical challenges.
We welcome original research articles, systematic reviews, and meta-analyses that investigate clinical, biological, psychological, and social factors influencing the course and prognosis of mood disorders. Studies addressing clinical neurobiological underpinnings, including genetic, epigenetic, and neuroimaging findings, are encouraged, as are contributions exploring transdiagnostic features, early markers of vulnerability, and longitudinal outcomes.
Submissions may also focus on pharmacological, psychotherapeutic, and integrative interventions, evaluating real-world effectiveness, predictors of response, adverse effects, and long-term adherence.
Of particular interest are works examining gender differences, comorbidities (e.g., substance use, anxiety, personality disorders), and the impact of life events, trauma, and affective temperament on treatment trajectories.
Our goal is to foster an inclusive, interdisciplinary dialogue that bridges research and clinical practice, providing a platform for innovative approaches to understanding and improving outcomes in bipolar and depressive disorders.
Dr. Luca J. Steardo
Dr. Francesco Monaco
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- mood disorders
- clinical outcomes
- treatment response
- psychopathology
- pathophysiology
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