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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Safety in Spinal Surgery

edited by Simon B. Roberts and

Thanos Tsirikos

submission deadline 15 Jan 2026 | 1 articles | Viewed by 3905 | Submission Open

Keywords: spinal surgery; patients with spinal deformity; inherent risks; risk management; surgery safety

(This special issue belongs to the Section General Surgery)

Clinical Management and Treatment of Psoriasis

edited by

Luciano Ibba

submission deadline 15 Jan 2026 | 2 articles | Viewed by 3483 | Submission Open

Keywords: psoriasis; biological drugs; personalized medicine; comorbidities; real-world evidence

(This special issue belongs to the Section Dermatology)

Clinical Advances in the Diagnosis and Treatment of Cardiac Arrhythmias

edited by Fabrizio Guarracini and

Marisa Varrenti

submission deadline 15 Jan 2026 | 3 articles | Viewed by 3039 | Submission Open

Keywords: cardiac arrhythmias; antiarrhythmic agents; pacemakers; cardiac resynchronization; catheter ablation; electrophysiology

(This special issue belongs to the Section Cardiology)

Up-to-Date Research in Liver Transplantation

edited by

Pierluigi Toniutto

submission deadline 15 Jan 2026 | 1 articles | Viewed by 2396 | Submission Open

Keywords: liver transplantation; acute or chronic liver diseases; hepatitis C virus infection; hepatocellular carcinoma (HCC); cirrhosis; intrahepatic (ICCA); perihilar (PCCA) cholangiocarcinoma; unresectable liver metastases; acute or chronic liver failure (ACLF); acute alcoholic hepatitis (AAH)

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Diagnosis and Management of Aortic Diseases: Drafting from Theoretical Aspects to Clinical Practice—2nd Edition

edited by

Mario D’Oria

submission deadline 15 Jan 2026 | 2 articles | Viewed by 1869 | Submission Open

Keywords: aortic disease; aortic aneurysm; aortic dissection; aortic surgery; diagnosis and management

(This special issue belongs to the Section Cardiovascular Medicine)

Pediatric Nephrology: Advances in the Diagnosis and Management of Pediatric Kidney Disorders

edited by

Agnieszka Rybi-Szumińska

and

Anna Maria Wasilewska

submission deadline 15 Jan 2026 | 3 articles | Viewed by 1792 | Submission Open

Keywords: diagnosis; management; treatment; kidney disorders; chronic kidney disease; biomarkers; genetic testing; kidney; children; newborn

(This special issue belongs to the Section Nephrology & Urology)

Recent Clinical Advances in Percutaneous Coronary Intervention

edited by

Lampson Fan

and Luke Pickup

submission deadline 15 Jan 2026 | 2 articles | Viewed by 1651 | Submission Open

Keywords: complex PCI; calcium modification; left main stem; stent; coronary artery disease; atherectomy; mechanical circula-tory support device; Impella; DCB; intra-coronary imaging; IVUS; OCT

(This special issue belongs to the Section Cardiology)

Intracranial Hemorrhage: Advances in Diagnosis, Management and Treatment

edited by Hitoshi Fukuda

submission deadline 15 Jan 2026 | 1 articles | Viewed by 978 | Submission Open

Keywords: intracerebral hemorrhage; subarachnoid hemorrhage; traumatic hemorrhage; prehospital care; less invasive surgery; vascular malformation; antihypertensive drug; intracranial pressure elevation; decompressive craniectomy; neurocritical care; nursing care; rehabilitation

(This special issue belongs to the Section Clinical Neurology)

Pediatric Urology: How to Adapt Current Knowledge to the New Era

edited by Simona Gerocarni Nappo and

Elisa Cerchia

submission deadline 15 Jan 2026 | 1 articles | Viewed by 693 | Submission Open

Keywords: pediatric urology; telemedicine; telesurgery; artificial intelligence; 3D-models; congenital urinary diseases; pediatric oncology

(This special issue belongs to the Section Clinical Pediatrics)

Advances in Oculoplastic Surgery and Ocular Surface Diseases

edited by Michael T. Yen, Francesco Quaranta Leoni and

Balestrazzi Alessandra

submission deadline 15 Jan 2026 | Viewed by 215 | Submission Open

Keywords: ocular surface disease; corneal neurotization; neurotrophic keratopathy; eyelid malposition; facial nerve palsy; thyroid eye disease; oculoplastic surgery; hemocomponents; dry anophthalmic socket; corneal pathology; ocular surface reconstruction; exposure keratopathy

(This special issue belongs to the Section Ophthalmology)

Chronic Kidney Disease: Current Challenges and Adverse Outcomes

edited by

Diana Tania Luminița Moldovan

and Flaviu Bob

submission deadline 15 Jan 2026 | Viewed by 160 | Submission Open

Keywords: chronic kidney disease; CKD progression; hemodialysis; cardiovascular complications; vascular calcification; lifestyle; nutrition; bone and mineral disorders; CKD-associated osteoporosis; mortality

(This special issue belongs to the Section Nephrology & Urology)

Advances in Minimally Invasive Cardiothoracic Surgery: Current Techniques and Future Innovations

edited by

Akshay Kumar

and

Mohamed Rahouma

submission deadline 15 Jan 2026 | Viewed by 150 | Submission Open

Keywords: cardiothoracic surgery; lung cancer; cardiac imaging; minimally invasive surgery; thoracic oncology

(This special issue belongs to the Section Cardiovascular Medicine)

Pulmonary Critical Care: Diagnosis and Treatment of Respiratory System Diseases

edited by Yaron Bar-Lavie

submission deadline 15 Jan 2026 | Viewed by 144 | Submission Open

Keywords: acute respiratory distress syndrome (ARDS); mechanical ventilation; chronic obstructive pulmonary disease (COPD); sepsis-induced lung injury; pulmonary fibrosis; bronchoscopy in critical care

(This special issue belongs to the Section Intensive Care)

Insights into Acute Pancreatitis: Pathogenesis, Diagnosis, and Management

edited by Gil Nissim Bachar and Ram Dickman

submission deadline 15 Jan 2026 | Viewed by 137 | Submission Open

Keywords: acute pancreatitis; pancreatic inflammation; necrotizing pancreatitis; clinical outcomes; ultrasound examination

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Updates on Epilepsy Researches

edited by

Guillermo Estivill-Torrús

submission deadline 15 Jan 2026 | Viewed by 136 | Submission Open

Keywords: epilepsy; autoimmune epilepsy; neural autoantibodies; seizure disorders; experimental epilepsy models; animal studies; neuronal excitability; immunotherapy; predictive scoring systems; epilepsy biomarkers

(This special issue belongs to the Section Clinical Neurology)

Artificial Intelligence in Gastrointestinal Disorders: Current Updates from Theory to Clinical Practice

edited by

Maria Pina Dore

and

Elettra Merola

submission deadline 15 Jan 2026 | Viewed by 134 | Submission Open

Keywords: artificial intelligence; gastroenterology; medical imaging; endoscopy; prognostic modeling; ethical considerations

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Diagnosis and Management of Chronic Venous Diseases

edited by

Sigitas Urbonavičius

submission deadline 15 Jan 2026 | Viewed by 97 | Submission Open

Keywords: varicose veins; chronic venous insufficiency; pathogenesis; operative treatment; conservative treatment; profilaxis

(This special issue belongs to the Section Vascular Medicine)

Novel Sepsis and Post-Sepsis Care: The Heart and Beyond

edited by Alexander Liu and

Barbara J. Philips

submission deadline 16 Jan 2026 | Viewed by 246 | Submission Open

Keywords: sepsis; post sepsis; inflammation; cardiomyopathy; heart failure; cardiac imaging; biomarkers; novel therapies; prognosis; clinical outcomes

Innovations in Plastic and Reconstructive Research

edited by Damiano Tambasco and Roberta Albanese

submission deadline 18 Jan 2026 | 4 articles | Viewed by 6194 | Submission Open

Keywords: microvascular surgery; 3D printing; regenerative medicine; aesthetic surgery; minimally invasive techniques

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

New Advances in Hip and Knee Arthroplasty

edited by Jun-Dong Chang

submission deadline 18 Jan 2026 | 1 articles | Viewed by 989 | Submission Open

Keywords: hip arthroplasty; knee arthroplasty; joint replacement; revision surgery; orthopedic implants; robotic surgery; peri-operative care; functional outcomes; complication management; orthopedic innovation

(This special issue belongs to the Section Orthopedics)

New Technologies in Neurosurgery: An Insight into the Future

edited by Ismail Zaed

submission deadline 19 Jan 2026 | 1 articles | Viewed by 1649 | Submission Open

Keywords: neurosurgery; training; technology; augmented reality; virtual reality; robot

(This special issue belongs to the Section Clinical Neurology)

Rheumatoid Arthritis: Clinical Updates on Diagnosis and Treatment

edited by

Shunsuke Mori

submission deadline 20 Jan 2026 | 12 articles | Viewed by 38898 | Submission Open

Keywords: rheumatoid arthritis; disease-modifying antirheumatic drugs (DMARDs); biological therapies; Janus kinase inhibitors (JAK inhibitors); treatment strategies; joint destruction; comorbidity; drug safety

(This special issue belongs to the Section Immunology & Rheumatology)

Cataract and Refractive Surgery, and Intraocular Lens (IOL) Implantation: Recent Advances and Perspectives

edited by Ehud I. Assia

submission deadline 20 Jan 2026 | 14 articles | Viewed by 19696 | Submission Open

Keywords: premium IOLs (multifocal and toric); IOL power calculation; biometry and imaging; complications and management; laser vision correction; phakic IOLs; femtosecond-laser-assisted cataract surgery; AI (artificial intelligence) and cataract/refractive surgery; accommodative lenses

(This special issue belongs to the Section Ophthalmology)

Chronic Complications of Type 2 Diabetes: Prevalence, Prevention, and Management

edited by

Ilias Migdalis

submission deadline 20 Jan 2026 | 9 articles | Viewed by 18946 | Submission Open

Keywords: pathogenesis of diabetic complications; epidemiology of diabetic complications; diabetic retinopathy; diabetic chronic kidney disease; diabetes neuropathies; coronary heart disease; peripheral vascular disease; hypertension and dyslipidemia in diabetes

(This special issue belongs to the Section Endocrinology & Metabolism)

Hernia Surgery and Postoperative Management

edited by Jacob Rosenberg

submission deadline 20 Jan 2026 | 5 articles | Viewed by 15775 | Submission Open

Keywords: hernia surgery; hernia repair; abdominal hernia; preoperative; intraoperative; postoperative; management; complications

(This special issue belongs to the Section General Surgery)

New Insights into Infectious Skin and Mucosal Diseases

edited by

Giulia Ciccarese

Sebastiano Recalcati

and Astrid Herzum

submission deadline 20 Jan 2026 | 6 articles | Viewed by 15677 | Submission Open

Keywords: exanthem; latent viruses; infectious diseases; skin eruptions; sexually transmitted infections

(This special issue belongs to the Section Dermatology)

Advanced Strategies and Innovations to Enhance Outcomes in Cardiac Ablation

edited by

Nikolaos K. Fragakis

and

Paschalis Karakasis

submission deadline 20 Jan 2026 | 4 articles | Viewed by 12277 | Submission Open

Keywords: arrhythmias; cardiac ablation; catheter technology; imaging; anticoagulation optimization; post-procedure care

(This special issue belongs to the Section Cardiology)

POTS, ME/CFS and Long COVID: Recent Advances and Future Direction

edited by Svetlana Blitshteyn

submission deadline 20 Jan 2026 | 2 articles | Viewed by 12168 | Submission Open

Keywords: POTS; ME/CFS; long COVID; dysautonomia; orthostatic intolerance; autoimmunity

(This special issue belongs to the Section Immunology & Rheumatology)

Multidisciplinarity in Thoraco-Pulmonary Diseases: Every Generation Needs a New Revolution. Insights from the XXII SIET National Meeting

edited by Federico Raveglia,

Carmelina C. Zirafa

and

Mohsen Ibrahim

submission deadline 20 Jan 2026 | 8 articles | Viewed by 11932 | Submission Open

Keywords: lung cancer; interventional endoscopy; upper airway reconstruction; robotic diagnosis; robotic surgery

(This special issue belongs to the Section Respiratory Medicine)

Oral Health in Children: Clinical Management

edited by

Yolanda Martinez Beneyto

submission deadline 20 Jan 2026 | 7 articles | Viewed by 9975 | Submission Open

Keywords: pediatric oral health; early childhood caries; preventive strategies; comprehensive clinical approach; early detection; oral care; minimal intervention dentistry

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Traumatic Brain Injury: Current Treatment and Future Options

edited by

Ismail Zaed

submission deadline 20 Jan 2026 | 5 articles | Viewed by 9152 | Submission Open

Keywords: traumatic brain injury; trauma; biomarkers; post-traumatic outcome; epidemiology

(This special issue belongs to the Section Clinical Neurology)

Foot and Ankle Surgery: State of the Art and Future Perspectives

edited by Sung Jae Kim and Jaehwang Song

submission deadline 20 Jan 2026 | 5 articles | Viewed by 9089 | Submission Open

Keywords: foot and ankle surgery; hallux disorders; lesser toe problem; diabetic foot salvage; calcaneal fracture; pilon fracture; ligament disorder

(This special issue belongs to the Section Orthopedics)

Attention-Deficit/Hyperactivity Disorder (ADHD): Advances in Diagnosis and Treatment

edited by Yanli Zhang-James

submission deadline 20 Jan 2026 | 3 articles | Viewed by 8921 | Submission Open

Keywords: attention-deficit/hyperactivity disorder; neurodevelopmental disorder; hyperactivity; children; adolescents; adult

(This special issue belongs to the Section Clinical Neurology)

Plastic Surgery: Challenges and Future Directions

edited by Philip Brazio and Edward C. Ray

submission deadline 20 Jan 2026 | 5 articles | Viewed by 7762 | Submission Open

Keywords: plastic surgery; reconstructive surgery; esthetic surgery; innovation; challenges; technology

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Innovative Clinical Approaches in Oral Health Prevention and Management

edited by

Giulia Orilisi

Rossana Izzetti

and Flavia Vitiello

submission deadline 20 Jan 2026 | 6 articles | Viewed by 7571 | Submission Open

Keywords: oral health; oral prevention; teeth remineralization; oral pathology; oral health management; preventive dentistry; translational dentistry

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Cardiovascular Imaging: Opportunities and Challenges in Clinical Application: 3rd Edition

edited by

Kana Fujikura

and Panagiota Christia

submission deadline 20 Jan 2026 | 4 articles | Viewed by 6969 | Submission Open

Keywords: echocardiography; cardiovascular magnetic resonance imaging; cardiovascular computed tomography imaging; nuclear cardiology imaging; stress test with imaging; multimodality cardiovascular imaging; cardiomyopathy; coronary artery disease; microvascular disease; valvular heart disease

(This special issue belongs to the Section Cardiology)

Peripheral Nerves: Imaging, Electrophysiology and Surgical Techniques

edited by

Raffaele Natella

, Aniello Iovino and Vito Stifano

submission deadline 20 Jan 2026 | 4 articles | Viewed by 6259 | Submission Open

Keywords: MRI; MSK imaging; soft-tissue tumors; DTI; neuropathies; inflammatory neuropathies; nerve entrapment; motor neuron disease; neurophysiology; MSK ultrasound; peripheral nerve tumor; nerve entrapment; nerve reconstruction

(This special issue belongs to the Section Clinical Neurology)

Hip Fracture and Surgery: Clinical Updates and Challenges

edited by

Norio Imai

submission deadline 20 Jan 2026 | 5 articles | Viewed by 6244 | Submission Open

Keywords: antiosteoporosis medication; fracture liaison service; osteosynthesis; total hip arthroplasty; hemiarthroplasty

(This special issue belongs to the Section Orthopedics)

Advancing Psycho-Oncology: Multidimensional Approaches and Challenges to Cancer Care

edited by

Benedetta Muzii

Nelson Mauro Maldonato

and

Andrea Bovero

submission deadline 20 Jan 2026 | 3 articles | Viewed by 5997 | Submission Open

Keywords: psycho-oncology; cancer care; adaptation process; illness experience; risk and protective factors; mental health care; oncofertility; palliative care; critical experience; prevention; qualitative and quantitative methods; quality of life; health behaviors

(This special issue belongs to the Section Mental Health)

Clinical Challenges of Pelvic Floor Disorders Management

edited by

Matteo Frigerio

submission deadline 20 Jan 2026 | 4 articles | Viewed by 5419 | Submission Open

Keywords: pelvic floor disorders; pelvic organ prolapse; urinary incontinence; surgery; diagnostics; pelvic pain; vulvodynia; urinary tract symptoms; mesh-related complications

(This special issue belongs to the Section Obstetrics & Gynecology)

New Advances in Cardiovascular Diseases: The Cutting Edge

edited by

Fabiana Lucà

submission deadline 20 Jan 2026 | 4 articles | Viewed by 5287 | Submission Open

Keywords: cardiovascular disease (CVD); preventive cardiology; cardiac pharmacology; coronary artery disease (CAD); heart failure (HF); atrial fibrillation (AF); supraventricular and ventricular arrhythmias

(This special issue belongs to the Section Cardiovascular Medicine)

Advances in Diagnosis, Risk Stratification, and Personalized Management in Acute Coronary Syndromes

edited by

Efstratios Karagiannidis

, Barbara P. Fyntanidou and

Aikaterini Apostolopoulou

submission deadline 20 Jan 2026 | 5 articles | Viewed by 5263 | Submission Open

Keywords: acute coronary syndrome (ACS); cardiovascular disease (CVD); ischemic heart disease; emergency medicine; risk stratification; personalized treatment; antiplatelets; primary and secondary prevention

(This special issue belongs to the Section Cardiology)

Eating Disorders: Current Epidemiology and Advances in Diagnosis and Treatment—Second Edition

edited by

Arthur Eumann Mesas

submission deadline 20 Jan 2026 | 4 articles | Viewed by 4655 | Submission Open

Keywords: eating disorder; bulimia nervosa; anorexia nervosa; binge eating disorder; sociocultural context; epidemiology; di-agnosis; treatment; prevention

(This special issue belongs to the Section Mental Health)

Microsurgery: Current and Future Challenges

edited by

Matthias Aitzetmüller-Klietz

submission deadline 20 Jan 2026 | 5 articles | Viewed by 4509 | Submission Open

Keywords: microsurgery; reconstruction; reconstructive surgery; breast reconstruction; extremity reconstruction

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Endodontic Disease: Prevalence, Risk Factors, and Treatment Outcome

edited by

Razvan Ionut Ghinea

Ioana-Sofia Pop-Ciutrilă

and

Luminita-Maria Nica

submission deadline 20 Jan 2026 | 3 articles | Viewed by 4175 | Submission Open

Keywords: endodontics; apical periodontitis; pulpitis; root canal treatment; risk factors; treatment outcomes; regenerative endodontics

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Artificial Intelligence (AI) and Deep Learning (DL) in Medical Imaging

edited by

Francesco Pucciarelli

submission deadline 20 Jan 2026 | 2 articles | Viewed by 4154 | Submission Open

Keywords: artificial intelligence; deep learning; imaging; diagnosis; precision medicine; oncologic

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Clinical Insights into Pediatric Critical Care

edited by Katherine Biagas and Daniel E Sloniewsky

submission deadline 20 Jan 2026 | 3 articles | Viewed by 4126 | Submission Open

Keywords: PICU; anemia; blood transfusion; critically ill children; traumatic hemorrhage

(This special issue belongs to the Section Intensive Care)

Sustaining Success Through Innovation in Kidney Transplantation

edited by Junji Uchida

submission deadline 20 Jan 2026 | 4 articles | Viewed by 4001 | Submission Open

Keywords: kidney transplantation; long-term graft survival; immunosuppression; organ shortage; post-transplant complication

(This special issue belongs to the Section Nephrology & Urology)

Long COVID and Cardiovascular Health: Clinical Perspectives on Risk and Management

edited by Mariana Tudoran and

Cristina Tudoran

submission deadline 20 Jan 2026 | 3 articles | Viewed by 3760 | Submission Open

Keywords: long COVID; cardiovascular disease; long COVID therapy; management of long COVID; mechanisms of long COVID

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Management of Cardiogenic Shock and Cardiac Arrest: 2nd Edition

edited by Jaime A. Hernández-Montfort

submission deadline 20 Jan 2026 | 3 articles | Viewed by 3733 | Submission Open

Keywords: cardiogenic shock; cardiac arrest; temporary mechanical circulatory support; ECMO; transitions; heart recovery; heart replacement

(This special issue belongs to the Section Cardiology)

Displaying special issue 401-450 on page 9 of 32.

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